FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7265, 352 aa 1>>>pF1KB7265 352 - 352 aa - 352 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7069+/-0.000289; mu= 15.0955+/- 0.018 mean_var=71.9688+/-14.406, 0's: 0 Z-trim(118.8): 64 B-trim: 1298 in 1/56 Lambda= 0.151183 statistics sampled from 32029 (32101) to 32029 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.376), width: 16 Scan time: 8.490 The best scores are: opt bits E(85289) NP_085096 (OMIM: 604480) NAD-dependent protein dea ( 352) 2387 529.2 5.2e-150 XP_006723174 (OMIM: 604480) PREDICTED: NAD-depende ( 352) 2387 529.2 5.2e-150 XP_011524956 (OMIM: 604480) PREDICTED: NAD-depende ( 352) 2387 529.2 5.2e-150 NP_036369 (OMIM: 604480) NAD-dependent protein dea ( 389) 2387 529.2 5.7e-150 XP_011524957 (OMIM: 604480) PREDICTED: NAD-depende ( 319) 2138 474.9 1.1e-133 XP_016881989 (OMIM: 604480) PREDICTED: NAD-depende ( 266) 1674 373.6 2.7e-103 NP_001180215 (OMIM: 604480) NAD-dependent protein ( 234) 1551 346.8 2.9e-95 NP_036371 (OMIM: 604481) NAD-dependent protein dea ( 399) 882 201.0 3.8e-51 XP_005252892 (OMIM: 604481) PREDICTED: NAD-depende ( 417) 882 201.0 4e-51 XP_016872919 (OMIM: 604481) PREDICTED: NAD-depende ( 257) 827 188.9 1.1e-47 NP_001017524 (OMIM: 604481) NAD-dependent protein ( 257) 827 188.9 1.1e-47 XP_011518259 (OMIM: 604481) PREDICTED: NAD-depende ( 275) 827 188.9 1.1e-47 XP_011518258 (OMIM: 604481) PREDICTED: NAD-depende ( 275) 827 188.9 1.1e-47 XP_016872917 (OMIM: 604481) PREDICTED: NAD-depende ( 275) 827 188.9 1.1e-47 XP_016872920 (OMIM: 604481) PREDICTED: NAD-depende ( 275) 827 188.9 1.1e-47 XP_016872918 (OMIM: 604481) PREDICTED: NAD-depende ( 275) 827 188.9 1.1e-47 NP_036370 (OMIM: 604479) NAD-dependent protein dea ( 747) 721 166.0 2.4e-40 NP_001135970 (OMIM: 604479) NAD-dependent protein ( 452) 572 133.4 9.6e-31 NP_001300978 (OMIM: 604479) NAD-dependent protein ( 444) 485 114.4 4.9e-25 NP_001180196 (OMIM: 604483) NAD-dependent protein ( 292) 266 66.6 8.1e-11 XP_006719372 (OMIM: 604482) PREDICTED: NAD-depende ( 314) 204 53.0 1e-06 XP_006719371 (OMIM: 604482) PREDICTED: NAD-depende ( 314) 204 53.0 1e-06 NP_036372 (OMIM: 604482) NAD-dependent protein lip ( 314) 204 53.0 1e-06 NP_001307987 (OMIM: 606211) NAD-dependent protein ( 283) 178 47.4 4.7e-05 NP_057623 (OMIM: 606211) NAD-dependent protein dea ( 355) 178 47.4 5.8e-05 XP_016866114 (OMIM: 604483) PREDICTED: NAD-depende ( 246) 162 43.8 0.00047 XP_016866113 (OMIM: 604483) PREDICTED: NAD-depende ( 255) 162 43.8 0.00049 XP_016866110 (OMIM: 604483) PREDICTED: NAD-depende ( 283) 162 43.9 0.00053 XP_006722347 (OMIM: 606212) PREDICTED: NAD-depende ( 318) 147 40.6 0.0057 XP_011521883 (OMIM: 606212) PREDICTED: NAD-depende ( 329) 147 40.6 0.0058 XP_011521882 (OMIM: 606212) PREDICTED: NAD-depende ( 365) 147 40.6 0.0064 NP_057622 (OMIM: 606212) NAD-dependent protein dea ( 400) 147 40.7 0.0069 >>NP_085096 (OMIM: 604480) NAD-dependent protein deacety (352 aa) initn: 2387 init1: 2387 opt: 2387 Z-score: 2814.1 bits: 529.2 E(85289): 5.2e-150 Smith-Waterman score: 2387; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352) 10 20 30 40 50 60 pF1KB7 MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 SPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 KGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 KGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 TPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 TPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 LSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGW 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 KKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_085 KKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ 310 320 330 340 350 >>XP_006723174 (OMIM: 604480) PREDICTED: NAD-dependent p (352 aa) initn: 2387 init1: 2387 opt: 2387 Z-score: 2814.1 bits: 529.2 E(85289): 5.2e-150 Smith-Waterman score: 2387; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352) 10 20 30 40 50 60 pF1KB7 MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 KGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 TPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGW 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 KKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ 310 320 330 340 350 >>XP_011524956 (OMIM: 604480) PREDICTED: NAD-dependent p (352 aa) initn: 2387 init1: 2387 opt: 2387 Z-score: 2814.1 bits: 529.2 E(85289): 5.2e-150 Smith-Waterman score: 2387; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352) 10 20 30 40 50 60 pF1KB7 MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 KGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 TPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGW 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 KKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ 310 320 330 340 350 >>NP_036369 (OMIM: 604480) NAD-dependent protein deacety (389 aa) initn: 2387 init1: 2387 opt: 2387 Z-score: 2813.4 bits: 529.2 E(85289): 5.7e-150 Smith-Waterman score: 2387; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:38-389) 10 20 30 pF1KB7 MDFLRNLFSQTLSLGSQKERLLDELTLEGV :::::::::::::::::::::::::::::: NP_036 HPLETQAGKVQEAQDSDSDSEGGAAGGEADMDFLRNLFSQTLSLGSQKERLLDELTLEGV 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 ARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKH 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 PEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAH 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 GTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCM 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 QSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 QSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGM 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 DFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQSGAGVPNPSTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 DFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQSGAGVPNPSTSA 310 320 330 340 350 360 340 350 pF1KB7 SPKKSPPPAKDEARTTEREKPQ :::::::::::::::::::::: NP_036 SPKKSPPPAKDEARTTEREKPQ 370 380 >>XP_011524957 (OMIM: 604480) PREDICTED: NAD-dependent p (319 aa) initn: 2138 init1: 2138 opt: 2138 Z-score: 2521.2 bits: 474.9 E(85289): 1.1e-133 Smith-Waterman score: 2138; 100.0% identity (100.0% similar) in 313 aa overlap (40-352:7-319) 10 20 30 40 50 60 pF1KB7 QTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDN :::::::::::::::::::::::::::::: XP_011 MAEPDRRRVICLVGAGISTSAGIPDFRSPSTGLYDN 10 20 30 70 80 90 100 110 120 pF1KB7 LEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYT 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB7 QNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB7 LVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLIN 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB7 KEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVR 220 230 240 250 260 270 310 320 330 340 350 pF1KB7 REHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ ::::::::::::::::::::::::::::::::::::::::::: XP_011 REHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ 280 290 300 310 >>XP_016881989 (OMIM: 604480) PREDICTED: NAD-dependent p (266 aa) initn: 1674 init1: 1674 opt: 1674 Z-score: 1975.5 bits: 373.6 E(85289): 2.7e-103 Smith-Waterman score: 1674; 99.2% identity (100.0% similar) in 247 aa overlap (106-352:20-266) 80 90 100 110 120 130 pF1KB7 PYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTL ..:::::::::::::::::::::::::::: XP_016 MRQWPVAVPCSRQQCCRSSLQPTICHYFMRLLKDKGLLLRCYTQNIDTL 10 20 30 40 140 150 160 170 180 190 pF1KB7 ERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDI 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB7 VFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQ 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB7 SDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASI 170 180 190 200 210 220 320 330 340 350 pF1KB7 DAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ ::::::::::::::::::::::::::::::::::::: XP_016 DAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ 230 240 250 260 >>NP_001180215 (OMIM: 604480) NAD-dependent protein deac (234 aa) initn: 1550 init1: 1550 opt: 1551 Z-score: 1831.4 bits: 346.8 E(85289): 2.9e-95 Smith-Waterman score: 1551; 98.3% identity (99.1% similar) in 233 aa overlap (1-233:1-233) 10 20 30 40 50 60 pF1KB7 MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 KGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 TPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAP :::::::::::::::::::::::::::::::::::::::::::::::: . .: NP_001 TPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQGRGLAG 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 LSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGW >>NP_036371 (OMIM: 604481) NAD-dependent protein deacety (399 aa) initn: 962 init1: 610 opt: 882 Z-score: 1039.2 bits: 201.0 E(85289): 3.8e-51 Smith-Waterman score: 968; 48.7% identity (75.6% similar) in 308 aa overlap (9-316:109-395) 10 20 30 pF1KB7 MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSER :.... :..... .:.:. ::. .... NP_036 FRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDK--GKLSLQDVAELIRARA 80 90 100 110 120 130 40 50 60 70 80 90 pF1KB7 CRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALA :.::. .::::::: .::::::::..:::.::..: :::::::::. .: ..:.:::.:: NP_036 CQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLA 140 150 160 170 180 190 100 110 120 130 140 150 pF1KB7 KELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHC ::::::..::.. :::.:::.::::::: :::::: :::..:. :::::::: .. : NP_036 KELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATC 200 210 220 230 240 250 160 170 180 190 200 210 pF1KB7 VSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVD . :.. .: .. .... .:.: : ..:::::::::: :: ::. . :: .: NP_036 TV--CQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHV-VDFPMAD 260 270 280 290 300 310 220 230 240 250 260 270 pF1KB7 LLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAY :::..::::.:.::::: . :.::::::.. : : . . .. NP_036 LLLILGTSLEVEPFASLTEAVRSSVPRLLINRD--------------LVGPLAWHPRS-- 320 330 340 350 280 290 300 310 320 330 pF1KB7 RDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPP :::: ::. .: .:.::::: .:..:::.:: ...: NP_036 RDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLDGPDK 360 370 380 390 340 350 pF1KB7 AKDEARTTEREKPQ >>XP_005252892 (OMIM: 604481) PREDICTED: NAD-dependent p (417 aa) initn: 956 init1: 610 opt: 882 Z-score: 1038.9 bits: 201.0 E(85289): 4e-51 Smith-Waterman score: 962; 48.5% identity (75.6% similar) in 307 aa overlap (9-315:109-394) 10 20 30 pF1KB7 MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSER :.... :..... .:.:. ::. .... XP_005 FRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDK--GKLSLQDVAELIRARA 80 90 100 110 120 130 40 50 60 70 80 90 pF1KB7 CRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALA :.::. .::::::: .::::::::..:::.::..: :::::::::. .: ..:.:::.:: XP_005 CQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLA 140 150 160 170 180 190 100 110 120 130 140 150 pF1KB7 KELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHC ::::::..::.. :::.:::.::::::: :::::: :::..:. :::::::: .. : XP_005 KELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATC 200 210 220 230 240 250 160 170 180 190 200 210 pF1KB7 VSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVD . :.. .: .. .... .:.: : ..:::::::::: :: ::. . :: .: XP_005 T--VCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHV-VDFPMAD 260 270 280 290 300 310 220 230 240 250 260 270 pF1KB7 LLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAY :::..::::.:.::::: . :.::::::.. : : . . .. XP_005 LLLILGTSLEVEPFASLTEAVRSSVPRLLINRD--------------LVGPLAWHPRS-- 320 330 340 350 280 290 300 310 320 330 pF1KB7 RDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPP :::: ::. .: .:.::::: .:..:::.:: ... XP_005 RDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKVQTAEEDHPRGCPSHCSRLDGPDK 360 370 380 390 400 410 340 350 pF1KB7 AKDEARTTEREKPQ >>XP_016872919 (OMIM: 604481) PREDICTED: NAD-dependent p (257 aa) initn: 905 init1: 553 opt: 827 Z-score: 977.3 bits: 188.9 E(85289): 1.1e-47 Smith-Waterman score: 913; 51.8% identity (75.4% similar) in 272 aa overlap (45-316:1-253) 20 30 40 50 60 70 pF1KB7 GSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYH .::::::: .::::::::..:::.::..: XP_016 MVGAGISTPSGIPDFRSPGSGLYSNLQQYD 10 20 30 80 90 100 110 120 130 pF1KB7 LPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDT :::::::::. .: ..:.:::.::::::::..::.. :::.:::.::::::: :::::: XP_016 LPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDG 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB7 LERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPD :::..:. :::::::: .. :. :.. .: .. .... .:.: : ..:::: XP_016 LERVSGIPASKLVEAHGTFASATCTV--CQRPFPGEDIRADVMADRVPRCPVCTGVVKPD 100 110 120 130 140 200 210 220 230 240 250 pF1KB7 IVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAG :::::: :: ::. . :: .::::..::::.:.::::: . :.::::::.. XP_016 IVFFGEPLPQRFLLHV-VDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRD--- 150 160 170 180 190 200 260 270 280 290 300 310 pF1KB7 QSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHAS : : . . .. :::: ::. .: .:.::::: .:..:::.:: .. XP_016 -----------LVGPLAWHPRS--RDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGK 210 220 230 240 250 320 330 340 350 pF1KB7 IDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ .: XP_016 LDGPDK 352 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:20:20 2016 done: Sat Nov 5 02:20:21 2016 Total Scan time: 8.490 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]