FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7266, 344 aa 1>>>pF1KB7266 344 - 344 aa - 344 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6097+/-0.00085; mu= 14.2196+/- 0.051 mean_var=69.0284+/-13.729, 0's: 0 Z-trim(106.7): 48 B-trim: 56 in 1/48 Lambda= 0.154369 statistics sampled from 9072 (9116) to 9072 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.28), width: 16 Scan time: 1.960 The best scores are: opt bits E(32554) CCDS11815.2 WDR45B gene_id:56270|Hs108|chr17 ( 344) 2361 534.9 3.7e-152 CCDS35250.1 WDR45 gene_id:11152|Hs108|chrX ( 360) 858 200.1 2.3e-51 CCDS14318.1 WDR45 gene_id:11152|Hs108|chrX ( 361) 858 200.2 2.3e-51 CCDS47532.1 WIPI2 gene_id:26100|Hs108|chr7 ( 425) 438 106.6 3.8e-23 CCDS34593.1 WIPI2 gene_id:26100|Hs108|chr7 ( 436) 438 106.6 3.8e-23 CCDS11677.1 WIPI1 gene_id:55062|Hs108|chr17 ( 446) 429 104.6 1.6e-22 CCDS47531.1 WIPI2 gene_id:26100|Hs108|chr7 ( 443) 388 95.5 8.7e-20 CCDS5339.1 WIPI2 gene_id:26100|Hs108|chr7 ( 454) 388 95.5 8.9e-20 CCDS82193.1 WIPI1 gene_id:55062|Hs108|chr17 ( 364) 382 94.1 1.9e-19 CCDS47533.1 WIPI2 gene_id:26100|Hs108|chr7 ( 384) 377 93.0 4.2e-19 >>CCDS11815.2 WDR45B gene_id:56270|Hs108|chr17 (344 aa) initn: 2361 init1: 2361 opt: 2361 Z-score: 2845.1 bits: 534.9 E(32554): 3.7e-152 Smith-Waterman score: 2361; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344) 10 20 30 40 50 60 pF1KB7 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVGHVEML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVGHVEML 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 KVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 KVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 DASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICA 250 260 270 280 290 300 310 320 330 340 pF1KB7 FGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL :::::::::::::::::::::::::::::::::::::::::::: CCDS11 FGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL 310 320 330 340 >>CCDS35250.1 WDR45 gene_id:11152|Hs108|chrX (360 aa) initn: 731 init1: 359 opt: 858 Z-score: 1035.8 bits: 200.1 E(32554): 2.3e-51 Smith-Waterman score: 1101; 47.9% identity (75.5% similar) in 351 aa overlap (12-342:8-357) 10 20 30 40 50 pF1KB7 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLE-GGVGHVEM :. ::::..:: :.::.: :.::..:: :: . . . :..: ::: CCDS35 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEM 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 LFRCNYLALVGGGKKPKYPPNKVMIWDDL------KKKTVIEIEFSTEVKAVKLRRDRIV : : : :::::::..::. .:.:::: :.: :.:. :. : .:..:.:.:: CCDS35 LHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 VVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLAS .:: . : :..: ::..: :.: :::::: :::. ...::.::: . : .::::::: CCDS35 IVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLAS 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 TEKP-----PVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGS : :: : : ::.. ..:..:: :: .:.::.::::::.:::.: . . :::::. CCDS35 T-KPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGT 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 QAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSSLASAS----FLPKYFSSKW . :..:::::..:.:..:.:::.::::::: .: . :..:.:: .. .. .: .:.: CCDS35 DPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQW 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 SFSKFQVPSGSPCICAFGTEP----NAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMT :...: ::. : :::::: . :.:::::.::...:..:.: :.: :... .:.. CCDS35 SLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDIC 300 310 320 330 340 350 pF1KB7 DDKL :: CCDS35 DDDDF 360 >>CCDS14318.1 WDR45 gene_id:11152|Hs108|chrX (361 aa) initn: 836 init1: 359 opt: 858 Z-score: 1035.7 bits: 200.2 E(32554): 2.3e-51 Smith-Waterman score: 1092; 47.7% identity (75.3% similar) in 352 aa overlap (12-342:8-358) 10 20 30 40 50 pF1KB7 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLE-GGVGHVEM :. ::::..:: :.::.: :.::..:: :: . . . :..: ::: CCDS14 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEM 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 LFRCNYLALVGGGKKPKYPP-NKVMIWDDL------KKKTVIEIEFSTEVKAVKLRRDRI : : : :::::::..::. . :.:::: :.: :.:. :. : .:..:.:.: CCDS14 LHRSNLLALVGGGSSPKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKI 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 VVVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLA :.:: . : :..: ::..: :.: :::::: :::. ...::.::: . : .:::::: CCDS14 VIVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLA 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 STEKP-----PVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRG :: :: : : ::.. ..:..:: :: .:.::.::::::.:::.: . . ::::: CCDS14 ST-KPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRG 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 SQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSSLASAS----FLPKYFSSK .. :..:::::..:.:..:.:::.::::::: .: . :..:.:: .. .. .: .:. CCDS14 TDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQ 240 250 260 270 280 290 290 300 310 320 330 pF1KB7 WSFSKFQVPSGSPCICAFGTEP----NAVIAICADGSYYKFLFNPKGECIRDVYAQFLEM ::...: ::. : :::::: . :.:::::.::...:..:.: :.: :... .:.. CCDS14 WSLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDI 300 310 320 330 340 350 340 pF1KB7 TDDKL :: CCDS14 CDDDDF 360 >>CCDS47532.1 WIPI2 gene_id:26100|Hs108|chr7 (425 aa) initn: 376 init1: 276 opt: 438 Z-score: 529.1 bits: 106.6 E(32554): 3.8e-23 Smith-Waterman score: 489; 32.3% identity (59.4% similar) in 350 aa overlap (10-328:11-349) 10 20 30 40 50 pF1KB7 MNLLPCNPHGNG-LLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEK-QEFLEG-GVGH : : ::.:.::::. .: : ..:.. .. . . . :. : . : CCDS47 MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 VEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVL :: :: . .:.:. : :. :. . : . . .:. . :::: :.:..: : CCDS47 VERLFSSSLVAIVSL-KAPR----KLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCL 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 DSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNSLLAFPGTHT-GHVQLVDL . . . :: ....:. :: :: :::.: :..: ::.::. : :.::. : CCDS47 EESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 ASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAA . . . ::::.. :. .:.. .::..::::::::.::.:. :. . :.::: . CCDS47 INLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRC 180 190 200 210 220 230 240 250 260 270 pF1KB7 NIYC-INFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS------------LASASFLP- : . :..:. .. .::. ::::: : :.. .::.:.:: CCDS47 VSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPS 240 250 260 270 280 290 280 290 300 310 320 pF1KB7 ---KYFSSKWSFSKFQVP-SGSPCICAFGTE---PNAVIAICADGSYYKFLFNPK--GEC ..:.. .:. ..: : ::...: : ... ::: : . ..:. ::: CCDS47 QVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGA-ADGYLYMYNLDPQEGGEC 300 310 320 330 340 330 340 pF1KB7 IRDVYAQFLEMTDDKL CCDS47 ALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYTDDLGAVGGACLEDEASAL 350 360 370 380 390 400 >>CCDS34593.1 WIPI2 gene_id:26100|Hs108|chr7 (436 aa) initn: 376 init1: 276 opt: 438 Z-score: 529.0 bits: 106.6 E(32554): 3.8e-23 Smith-Waterman score: 489; 32.3% identity (59.4% similar) in 350 aa overlap (10-328:11-349) 10 20 30 40 50 pF1KB7 MNLLPCNPHGNG-LLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEK-QEFLEG-GVGH : : ::.:.::::. .: : ..:.. .. . . . :. : . : CCDS34 MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 VEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVL :: :: . .:.:. : :. :. . : . . .:. . :::: :.:..: : CCDS34 VERLFSSSLVAIVSL-KAPR----KLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCL 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 DSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNSLLAFPGTHT-GHVQLVDL . . . :: ....:. :: :: :::.: :..: ::.::. : :.::. : CCDS34 EESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 ASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAA . . . ::::.. :. .:.. .::..::::::::.::.:. :. . :.::: . CCDS34 INLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRC 180 190 200 210 220 230 240 250 260 270 pF1KB7 NIYC-INFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS------------LASASFLP- : . :..:. .. .::. ::::: : :.. .::.:.:: CCDS34 VSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPS 240 250 260 270 280 290 280 290 300 310 320 pF1KB7 ---KYFSSKWSFSKFQVP-SGSPCICAFGTE---PNAVIAICADGSYYKFLFNPK--GEC ..:.. .:. ..: : ::...: : ... ::: : . ..:. ::: CCDS34 QVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGA-ADGYLYMYNLDPQEGGEC 300 310 320 330 340 330 340 pF1KB7 IRDVYAQFLEMTDDKL CCDS34 ALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVG 350 360 370 380 390 400 >>CCDS11677.1 WIPI1 gene_id:55062|Hs108|chr17 (446 aa) initn: 279 init1: 250 opt: 429 Z-score: 518.0 bits: 104.6 E(32554): 1.6e-22 Smith-Waterman score: 451; 29.9% identity (61.4% similar) in 345 aa overlap (18-329:22-352) 10 20 30 40 50 pF1KB7 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGG--- :::: .: : . :..... :. :. . ..:. CCDS11 MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFS---LSSVEQLDQVHGSNEI 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 --VGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDR : :: :: . ...:. : : .. .. : . . .:... ...: :.: CCDS11 PDVYIVERLFSSSLVVVVSHTK-----PRQMNVYHFKKGTEICNYSYSSNILSIRLNRQR 60 70 80 90 100 110 120 130 140 150 160 pF1KB7 IVVVLDSMIKVFTFTHNPHQLHVFETCY----NPKGLCVLCPNSNNSLLAFPGTHT-GHV ..: :. : . :: .......: :: :::.: : .:: ::.::. : :.. CCDS11 LLVCLEESI----YIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEI 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 QLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRR : : ... : : ::::.:. :..: .:...:.::::::.::.:.. .:. . :.:: CCDS11 VLYD-GNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRR 170 180 190 200 210 220 230 240 250 260 270 pF1KB7 G-SQAANIYCINFNQDASLICVSSDHGTVHIFAAED--PKRNKQSS----------LASA : .. ..: . :..:....:.::. ::::: :. .: .. : .:.. CCDS11 GMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAAT 230 240 250 260 270 280 280 290 300 310 320 pF1KB7 SFLPKYFSSKW----SFSKFQVP-SGSPCICAFGT---EPNAVIAICADGSYYKFLFNPK ..:: :. .:. .. ::. ::...: : ..: ..: : . ..:. CCDS11 NYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVA-SSSGHLYMYNLDPQ 290 300 310 320 330 340 330 340 pF1KB7 --GECIRDVYAQFLEMTDDKL :::. CCDS11 DGGECVLIKTHSLLGSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGAL 350 360 370 380 390 400 >>CCDS47531.1 WIPI2 gene_id:26100|Hs108|chr7 (443 aa) initn: 343 init1: 276 opt: 388 Z-score: 468.7 bits: 95.5 E(32554): 8.7e-20 Smith-Waterman score: 443; 30.7% identity (56.5% similar) in 368 aa overlap (10-328:11-367) 10 20 30 40 pF1KB7 MNLLPCNPHGNG-LLYAGFNQDHG------------------CFACGMENGFRVYNTDP : : ::.:.::::. .: : ..:.. .. . CCDS47 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS 10 20 30 40 50 60 50 60 70 80 90 pF1KB7 LKEKEK-QEFLEG-GVGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEF . . :. : . : :: :: . .:.:. : :. :. . : . . . CCDS47 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSL-KAPR----KLKVCHFKKGTEICNYSY 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 STEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNS :. . :::: :.:..: :. . . :: ....:. :: :: :::.: :..: CCDS47 SNTILAVKLNRQRLIVCLEESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNC 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 LLAFPGTHT-GHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIF ::.::. : :.::. : . . . ::::.. :. .:.. .::..::::::::.::.: CCDS47 YLAYPGSATIGEVQVFDTINLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVF 180 190 200 210 220 230 220 230 240 250 260 pF1KB7 DTSSGHLIQELRRGSQAANIYC-INFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS--- . :. . :.::: . : . :..:. .. .::. ::::: : :.. CCDS47 SIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTT 240 250 260 270 280 290 270 280 290 300 310 pF1KB7 ---------LASASFLP----KYFSSKWSFSKFQVP-SGSPCICAFGTE---PNAVIAIC .::.:.:: ..:.. .:. ..: : ::...: : ... CCDS47 WTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGA- 300 310 320 330 340 320 330 340 pF1KB7 ADGSYYKFLFNPK--GECIRDVYAQFLEMTDDKL ::: : . ..:. ::: CCDS47 ADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYT 350 360 370 380 390 400 >>CCDS5339.1 WIPI2 gene_id:26100|Hs108|chr7 (454 aa) initn: 343 init1: 276 opt: 388 Z-score: 468.5 bits: 95.5 E(32554): 8.9e-20 Smith-Waterman score: 443; 30.7% identity (56.5% similar) in 368 aa overlap (10-328:11-367) 10 20 30 40 pF1KB7 MNLLPCNPHGNG-LLYAGFNQDHG------------------CFACGMENGFRVYNTDP : : ::.:.::::. .: : ..:.. .. . CCDS53 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS 10 20 30 40 50 60 50 60 70 80 90 pF1KB7 LKEKEK-QEFLEG-GVGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEF . . :. : . : :: :: . .:.:. : :. :. . : . . . CCDS53 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSL-KAPR----KLKVCHFKKGTEICNYSY 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 STEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNS :. . :::: :.:..: :. . . :: ....:. :: :: :::.: :..: CCDS53 SNTILAVKLNRQRLIVCLEESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNC 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 LLAFPGTHT-GHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIF ::.::. : :.::. : . . . ::::.. :. .:.. .::..::::::::.::.: CCDS53 YLAYPGSATIGEVQVFDTINLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVF 180 190 200 210 220 230 220 230 240 250 260 pF1KB7 DTSSGHLIQELRRGSQAANIYC-INFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS--- . :. . :.::: . : . :..:. .. .::. ::::: : :.. CCDS53 SIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTT 240 250 260 270 280 290 270 280 290 300 310 pF1KB7 ---------LASASFLP----KYFSSKWSFSKFQVP-SGSPCICAFGTE---PNAVIAIC .::.:.:: ..:.. .:. ..: : ::...: : ... CCDS53 WTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGA- 300 310 320 330 340 320 330 340 pF1KB7 ADGSYYKFLFNPK--GECIRDVYAQFLEMTDDKL ::: : . ..:. ::: CCDS53 ADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTY 350 360 370 380 390 400 >>CCDS82193.1 WIPI1 gene_id:55062|Hs108|chr17 (364 aa) initn: 279 init1: 250 opt: 382 Z-score: 462.8 bits: 94.1 E(32554): 1.9e-19 Smith-Waterman score: 404; 32.5% identity (64.6% similar) in 271 aa overlap (88-329:6-270) 60 70 80 90 100 110 pF1KB7 EMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVI-EIEFSTEVKAVKLRRDRIVVVL .:: : : . .:... ...: :.:..: : CCDS82 MNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCL 10 20 30 120 130 140 150 160 170 pF1KB7 DSMIKVFTFTHNPHQLHVFETCY----NPKGLCVLCPNSNNSLLAFPGTHT-GHVQLVDL . : . :: .......: :: :::.: : .:: ::.::. : :.. : : CCDS82 EESI----YIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYD- 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB7 ASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRG-SQA ... : : ::::.:. :..: .:...:.::::::.::.:.. .:. . :.::: .. CCDS82 GNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRY 100 110 120 130 140 150 240 250 260 270 pF1KB7 ANIYCINFNQDASLICVSSDHGTVHIFAAED--PKRNKQSS----------LASASFLPK ..: . :..:....:.::. ::::: :. .: .. : .:....:: CCDS82 VTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPT 160 170 180 190 200 210 280 290 300 310 320 pF1KB7 YFSSKW----SFSKFQVP-SGSPCICAFGT---EPNAVIAICADGSYYKFLFNPK--GEC :. .:. .. ::. ::...: : ..: ..: : . ..:. ::: CCDS82 QVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVA-SSSGHLYMYNLDPQDGGEC 220 230 240 250 260 330 340 pF1KB7 IRDVYAQFLEMTDDKL . CCDS82 VLIKTHSLLGSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGALRGEVI 270 280 290 300 310 320 >>CCDS47533.1 WIPI2 gene_id:26100|Hs108|chr7 (384 aa) initn: 307 init1: 276 opt: 377 Z-score: 456.4 bits: 93.0 E(32554): 4.2e-19 Smith-Waterman score: 428; 32.7% identity (59.3% similar) in 300 aa overlap (57-328:20-308) 30 40 50 60 70 80 pF1KB7 CGMENGFRVYNTDPLKEKEKQEFLEGGVGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWD :: :: . .:.:. : :. :. . CCDS47 MFTHVLPFVISADTEDVCIVERLFSSSLVAIVSL-KAPR----KLKVCH 10 20 30 40 90 100 110 120 130 140 pF1KB7 DLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVF----ETCYNPK : . . .:. . :::: :.:..: :. . . :: ....:. :: :: CCDS47 FKKGTEICNYSYSNTILAVKLNRQRLIVCLEESL----YIHNIRDMKVLHTIRETPPNPA 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB7 GLCVLCPNSNNSLLAFPGTHT-GHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIA :::.: :..: ::.::. : :.::. : . . . ::::.. :. .:.. .::..: CCDS47 GLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANM-IPAHDSPLAALAFDASGTKLA 110 120 130 140 150 210 220 230 240 250 260 pF1KB7 TASEKGTLIRIFDTSSGHLIQELRRGSQAANIYC-INFNQDASLICVSSDHGTVHIFAAE :::::::.::.:. :. . :.::: . : . :..:. .. .::. ::::: : CCDS47 TASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLE 160 170 180 190 200 210 270 280 290 300 pF1KB7 DPKRNKQSS------------LASASFLP----KYFSSKWSFSKFQVP-SGSPCICAFGT :.. .::.:.:: ..:.. .:. ..: : ::...: CCDS47 TVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLAT 220 230 240 250 260 270 310 320 330 340 pF1KB7 E---PNAVIAICADGSYYKFLFNPK--GECIRDVYAQFLEMTDDKL : ... ::: : . ..:. ::: CCDS47 IQKIPRLLVGA-ADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVT 280 290 300 310 320 330 344 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:28:50 2016 done: Fri Nov 4 06:28:50 2016 Total Scan time: 1.960 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]