FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7271, 495 aa 1>>>pF1KB7271 495 - 495 aa - 495 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.6619+/-0.00109; mu= -6.1679+/- 0.064 mean_var=407.9670+/-93.251, 0's: 0 Z-trim(113.9): 646 B-trim: 0 in 0/53 Lambda= 0.063498 statistics sampled from 13672 (14454) to 13672 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.768), E-opt: 0.2 (0.444), width: 16 Scan time: 3.840 The best scores are: opt bits E(32554) CCDS54333.1 KLF11 gene_id:8462|Hs108|chr2 ( 495) 3399 325.8 6.8e-89 CCDS1668.1 KLF11 gene_id:8462|Hs108|chr2 ( 512) 3399 325.8 6.9e-89 CCDS6294.1 KLF10 gene_id:7071|Hs108|chr8 ( 480) 907 97.5 3.5e-20 CCDS47905.1 KLF10 gene_id:7071|Hs108|chr8 ( 469) 904 97.2 4.2e-20 >>CCDS54333.1 KLF11 gene_id:8462|Hs108|chr2 (495 aa) initn: 3399 init1: 3399 opt: 3399 Z-score: 1709.5 bits: 325.8 E(32554): 6.8e-89 Smith-Waterman score: 3399; 100.0% identity (100.0% similar) in 495 aa overlap (1-495:1-495) 10 20 30 40 50 60 pF1KB7 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQRSQKGDLLRIRPLTPVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQRSQKGDLLRIRPLTPVSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTATD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFIT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFAR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 SDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIAS 430 440 450 460 470 480 490 pF1KB7 AESPGSPLVSMPASA ::::::::::::::: CCDS54 AESPGSPLVSMPASA 490 >>CCDS1668.1 KLF11 gene_id:8462|Hs108|chr2 (512 aa) initn: 3399 init1: 3399 opt: 3399 Z-score: 1709.3 bits: 325.8 E(32554): 6.9e-89 Smith-Waterman score: 3399; 100.0% identity (100.0% similar) in 495 aa overlap (1-495:18-512) 10 20 30 40 pF1KB7 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQR ::::::::::::::::::::::::::::::::::::::::::: CCDS16 MHTPDFAGPDDARAVDIMDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQR 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 SQKGDLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 SQKGDLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTR 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 TPVSPQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 TPVSPQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 ESPAACFPTIQTPDCRLSDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 ESPAACFPTIQTPDCRLSDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB7 LLLTDKGQQAGWPGAVQTCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 LLLTDKGQQAGWPGAVQTCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB7 AFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 AFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMA 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB7 AGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 AGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTG 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB7 EKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 EKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTK 430 440 450 460 470 480 470 480 490 pF1KB7 KIPGWQAEVGKLNRIASAESPGSPLVSMPASA :::::::::::::::::::::::::::::::: CCDS16 KIPGWQAEVGKLNRIASAESPGSPLVSMPASA 490 500 510 >>CCDS6294.1 KLF10 gene_id:7071|Hs108|chr8 (480 aa) initn: 942 init1: 740 opt: 907 Z-score: 475.8 bits: 97.5 E(32554): 3.5e-20 Smith-Waterman score: 1046; 40.6% identity (61.8% similar) in 495 aa overlap (5-484:17-476) 10 20 30 40 pF1KB7 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMS-SWGQRSQKG : : :: . .: : . :..:.::::::. :: :: . .: CCDS62 MLNFGASLQQTAEERMEMISERPK-ESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKK- 10 20 30 40 50 50 60 70 80 90 100 pF1KB7 DLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVS .. ::.::::: .. .. .:: :::.. ..:.::: ::. ::: :: CCDS62 -YVENRPVTPVSD---LSEEENLLPGTP----DFHTIPAFCLTPPYSPSDFEPSQ---VS 60 70 80 90 100 110 120 130 140 150 160 pF1KB7 PQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPV--PSSPCRAKGTSVIRHTGES .. . . . :...: : :. :: :. : .:..:::::::... CCDS62 NLMAPAPSTVHFKSLSDTAKPHIAAPFKEEEK----SPVSAPKLP-KAQATSVIRHTADA 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 PAACFPTIQTPDCRLSDSREGEEQLLGHFET-LQDTHLTDSLLSTNLVSCQPCLHKSGGL : . . ... . :... .. . .: : .:. .. CCDS62 QLCNHQTCPMKAASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCE----RNTVA 170 180 190 200 210 230 240 250 260 270 pF1KB7 LLTDKGQQAGWPGAVQT-----CSPKNYENDLPRKTTPLIS---VS---VPAPPVLCQMI . .:.. : . .: . : . . :.. . :.: :: :: ::.:::. CCDS62 DVDEKASAALYDFSVPSSETVICRSQPAPVS-PQQKSVLVSPPAVSAGGVPPMPVICQMV 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB7 PVTGQSSMLPAFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPP : ::: . : .: : : : ::.: ::.::::.:.:: .. CCDS62 P-------LPA--NNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQPVVQS 280 290 300 310 320 340 350 360 370 380 390 pF1KB7 PAPCAANVMAAGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSH : :.. ..:.: :.:::: : :. . .::.: :: :...:: ::: :::::::: CCDS62 SKP---PVVSPNGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFKSSH 330 340 350 360 370 380 400 410 420 430 440 450 pF1KB7 LKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLT :::: :::::::::.::: ::...::::::::::::::::::::.::.:::::::::::: CCDS62 LKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLT 390 400 410 420 430 440 460 470 480 490 pF1KB7 KHARRHMTTKKIPGWQAEVGKLNRIASAESPGSPLVSMPASA ::::::...::.:.:: ::.::: :: .: CCDS62 KHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ 450 460 470 480 >>CCDS47905.1 KLF10 gene_id:7071|Hs108|chr8 (469 aa) initn: 942 init1: 740 opt: 904 Z-score: 474.5 bits: 97.2 E(32554): 4.2e-20 Smith-Waterman score: 1046; 40.6% identity (61.8% similar) in 495 aa overlap (5-484:6-465) 10 20 30 40 50 pF1KB7 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMS-SWGQRSQKGDLLRIRPLTPV : : :: . .: : . :..:.::::::. :: :: . .: .. ::.::: CCDS47 MEERMEMISERPK-ESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKK--YVENRPVTPV 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 SDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTA :: .. .. .:: :::.. ..:.::: ::. ::: :: .. . . . CCDS47 SD---LSEEENLLPGTP----DFHTIPAFCLTPPYSPSDFEPSQ---VSNLMAPAPSTVH 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 TDVLQSSAVVARALSGGAERGLLGLEPV--PSSPCRAKGTSVIRHTGESPAACFPTIQTP :...: : :. :: :. : .:..:::::::... : CCDS47 FKSLSDTAKPHIAAPFKEEEK----SPVSAPKLP-KAQATSVIRHTADAQLCNHQTCPMK 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 DCRLSDSREGEEQLLGHFET-LQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGW . . ... . :... .. . .: : .:. .. . .:.. : . CCDS47 AASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCE----RNTVADVDEKASAALY 170 180 190 200 210 240 250 260 270 280 pF1KB7 PGAVQT-----CSPKNYENDLPRKTTPLIS---VS---VPAPPVLCQMIPVTGQSSMLPA .: . : . . :.. . :.: :: :: ::.:::.: ::: CCDS47 DFSVPSSETVICRSQPAPVS-PQQKSVLVSPPAVSAGGVPPMPVICQMVP-------LPA 220 230 240 250 260 270 290 300 310 320 330 340 pF1KB7 FLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAA . : .: : : : ::.: ::.::::.:.:: .. : :.. CCDS47 --NNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQPVVQSSKP---PVVSP 280 290 300 310 320 350 360 370 380 390 400 pF1KB7 GNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGE ..:.: :.:::: : :. . .::.: :: :...:: ::: :::::::::::: :::::: CCDS47 NGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGE 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB7 KPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKK :::.::: ::...::::::::::::::::::::.::.::::::::::::::::::...:: CCDS47 KPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKK 390 400 410 420 430 440 470 480 490 pF1KB7 IPGWQAEVGKLNRIASAESPGSPLVSMPASA .:.:: ::.::: :: .: CCDS47 LPNWQMEVSKLNDIALPPTPAPTQ 450 460 495 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:31:48 2016 done: Fri Nov 4 06:31:49 2016 Total Scan time: 3.840 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]