FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7271, 495 aa 1>>>pF1KB7271 495 - 495 aa - 495 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.9366+/-0.000438; mu= -1.4140+/- 0.027 mean_var=519.3115+/-124.476, 0's: 0 Z-trim(121.3): 908 B-trim: 2035 in 1/57 Lambda= 0.056281 statistics sampled from 36303 (37780) to 36303 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.443), width: 16 Scan time: 11.690 The best scores are: opt bits E(85289) NP_001171189 (OMIM: 603301,610508) Krueppel-like f ( 495) 3399 291.0 5.2e-78 NP_001171187 (OMIM: 603301,610508) Krueppel-like f ( 495) 3399 291.0 5.2e-78 NP_003588 (OMIM: 603301,610508) Krueppel-like fact ( 512) 3399 291.0 5.3e-78 NP_005646 (OMIM: 601878) Krueppel-like factor 10 i ( 480) 907 88.6 4.2e-17 NP_001027453 (OMIM: 601878) Krueppel-like factor 1 ( 469) 904 88.4 4.9e-17 NP_057079 (OMIM: 605328,612001) Krueppel-like fact ( 288) 530 57.7 5.2e-08 NP_114124 (OMIM: 606139) Krueppel-like factor 16 [ ( 252) 526 57.3 6e-08 NP_001273747 (OMIM: 602903) Krueppel-like factor 5 ( 366) 509 56.2 1.9e-07 NP_619638 (OMIM: 609393) Krueppel-like factor 14 [ ( 323) 507 55.9 2e-07 NP_001721 (OMIM: 602903) Krueppel-like factor 5 is ( 457) 509 56.3 2.2e-07 XP_016884739 (OMIM: 300286) PREDICTED: Krueppel-li ( 354) 488 54.4 6.2e-07 XP_011529061 (OMIM: 300286) PREDICTED: Krueppel-li ( 354) 488 54.4 6.2e-07 NP_001311034 (OMIM: 300286) Krueppel-like factor 8 ( 356) 488 54.4 6.2e-07 NP_009181 (OMIM: 300286) Krueppel-like factor 8 is ( 359) 488 54.4 6.2e-07 NP_001311031 (OMIM: 300286) Krueppel-like factor 8 ( 359) 488 54.4 6.2e-07 XP_005262034 (OMIM: 300286) PREDICTED: Krueppel-li ( 359) 488 54.4 6.2e-07 XP_005262036 (OMIM: 300286) PREDICTED: Krueppel-li ( 359) 488 54.4 6.2e-07 NP_001311033 (OMIM: 300286) Krueppel-like factor 8 ( 364) 488 54.4 6.3e-07 NP_057354 (OMIM: 602016) Krueppel-like factor 2 [H ( 355) 486 54.3 6.9e-07 NP_054798 (OMIM: 606465) Krueppel-like factor 15 [ ( 416) 487 54.5 7.1e-07 XP_005247457 (OMIM: 606465) PREDICTED: Krueppel-li ( 416) 487 54.5 7.1e-07 XP_011511045 (OMIM: 606465) PREDICTED: Krueppel-li ( 435) 487 54.5 7.3e-07 NP_001238754 (OMIM: 189906) transcription factor S ( 737) 488 54.9 9.3e-07 XP_011536998 (OMIM: 189906) PREDICTED: transcripti ( 778) 488 54.9 9.6e-07 NP_003100 (OMIM: 189906) transcription factor Sp1 ( 778) 488 54.9 9.6e-07 NP_612482 (OMIM: 189906) transcription factor Sp1 ( 785) 488 54.9 9.6e-07 NP_001003845 (OMIM: 609391) transcription factor S ( 398) 476 53.5 1.3e-06 XP_005246599 (OMIM: 609391) PREDICTED: transcripti ( 442) 476 53.6 1.4e-06 XP_011509461 (OMIM: 609391) PREDICTED: transcripti ( 454) 476 53.6 1.4e-06 NP_001197 (OMIM: 602902) Krueppel-like factor 9 [H ( 244) 468 52.6 1.5e-06 XP_011525944 (OMIM: 111150,600599,613566,613673) P ( 324) 462 52.3 2.5e-06 NP_006554 (OMIM: 111150,600599,613566,613673) Krue ( 362) 462 52.3 2.7e-06 XP_016875874 (OMIM: 607531) PREDICTED: Krueppel-li ( 352) 461 52.2 2.8e-06 XP_011533214 (OMIM: 607531) PREDICTED: Krueppel-li ( 383) 461 52.3 2.9e-06 XP_011533213 (OMIM: 607531) PREDICTED: Krueppel-li ( 383) 461 52.3 2.9e-06 NP_001017371 (OMIM: 601804) transcription factor S ( 713) 467 53.2 3e-06 XP_016875873 (OMIM: 607531) PREDICTED: Krueppel-li ( 393) 461 52.3 3e-06 XP_011533212 (OMIM: 607531) PREDICTED: Krueppel-li ( 400) 461 52.3 3e-06 XP_005266308 (OMIM: 607531) PREDICTED: Krueppel-li ( 402) 461 52.3 3e-06 XP_011533211 (OMIM: 607531) PREDICTED: Krueppel-li ( 402) 461 52.3 3e-06 NP_009180 (OMIM: 607531) Krueppel-like factor 12 [ ( 402) 461 52.3 3e-06 XP_011533209 (OMIM: 607531) PREDICTED: Krueppel-li ( 415) 461 52.3 3.1e-06 NP_001166183 (OMIM: 601804) transcription factor S ( 778) 467 53.2 3.1e-06 NP_003102 (OMIM: 601804) transcription factor Sp3 ( 781) 467 53.2 3.1e-06 NP_001300981 (OMIM: 602253) Krueppel-like factor 4 ( 513) 461 52.5 3.5e-06 NP_945194 (OMIM: 608306) transcription factor Sp8 ( 490) 458 52.2 4e-06 NP_874359 (OMIM: 608306) transcription factor Sp8 ( 508) 458 52.2 4.1e-06 NP_001313472 (OMIM: 600540) transcription factor S ( 471) 452 51.7 5.5e-06 XP_016863768 (OMIM: 609392) PREDICTED: Krueppel-li ( 320) 448 51.1 5.5e-06 NP_057615 (OMIM: 609392) Krueppel-like factor 3 [H ( 345) 448 51.2 5.8e-06 >>NP_001171189 (OMIM: 603301,610508) Krueppel-like facto (495 aa) initn: 3399 init1: 3399 opt: 3399 Z-score: 1521.5 bits: 291.0 E(85289): 5.2e-78 Smith-Waterman score: 3399; 100.0% identity (100.0% similar) in 495 aa overlap (1-495:1-495) 10 20 30 40 50 60 pF1KB7 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQRSQKGDLLRIRPLTPVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQRSQKGDLLRIRPLTPVSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTATD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFIT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFAR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 SDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIAS 430 440 450 460 470 480 490 pF1KB7 AESPGSPLVSMPASA ::::::::::::::: NP_001 AESPGSPLVSMPASA 490 >>NP_001171187 (OMIM: 603301,610508) Krueppel-like facto (495 aa) initn: 3399 init1: 3399 opt: 3399 Z-score: 1521.5 bits: 291.0 E(85289): 5.2e-78 Smith-Waterman score: 3399; 100.0% identity (100.0% similar) in 495 aa overlap (1-495:1-495) 10 20 30 40 50 60 pF1KB7 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQRSQKGDLLRIRPLTPVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQRSQKGDLLRIRPLTPVSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTATD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFIT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFAR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 SDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIAS 430 440 450 460 470 480 490 pF1KB7 AESPGSPLVSMPASA ::::::::::::::: NP_001 AESPGSPLVSMPASA 490 >>NP_003588 (OMIM: 603301,610508) Krueppel-like factor 1 (512 aa) initn: 3399 init1: 3399 opt: 3399 Z-score: 1521.3 bits: 291.0 E(85289): 5.3e-78 Smith-Waterman score: 3399; 100.0% identity (100.0% similar) in 495 aa overlap (1-495:18-512) 10 20 30 40 pF1KB7 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQR ::::::::::::::::::::::::::::::::::::::::::: NP_003 MHTPDFAGPDDARAVDIMDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQR 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 SQKGDLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SQKGDLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTR 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 TPVSPQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TPVSPQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 ESPAACFPTIQTPDCRLSDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ESPAACFPTIQTPDCRLSDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB7 LLLTDKGQQAGWPGAVQTCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LLLTDKGQQAGWPGAVQTCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB7 AFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMA 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB7 AGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTG 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB7 EKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTK 430 440 450 460 470 480 470 480 490 pF1KB7 KIPGWQAEVGKLNRIASAESPGSPLVSMPASA :::::::::::::::::::::::::::::::: NP_003 KIPGWQAEVGKLNRIASAESPGSPLVSMPASA 490 500 510 >>NP_005646 (OMIM: 601878) Krueppel-like factor 10 isofo (480 aa) initn: 942 init1: 740 opt: 907 Z-score: 428.1 bits: 88.6 E(85289): 4.2e-17 Smith-Waterman score: 1046; 40.6% identity (61.8% similar) in 495 aa overlap (5-484:17-476) 10 20 30 40 pF1KB7 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMS-SWGQRSQKG : : :: . .: : . :..:.::::::. :: :: . .: NP_005 MLNFGASLQQTAEERMEMISERPK-ESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKK- 10 20 30 40 50 50 60 70 80 90 100 pF1KB7 DLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVS .. ::.::::: .. .. .:: :::.. ..:.::: ::. ::: :: NP_005 -YVENRPVTPVSD---LSEEENLLPGTP----DFHTIPAFCLTPPYSPSDFEPSQ---VS 60 70 80 90 100 110 120 130 140 150 160 pF1KB7 PQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPV--PSSPCRAKGTSVIRHTGES .. . . . :...: : :. :: :. : .:..:::::::... NP_005 NLMAPAPSTVHFKSLSDTAKPHIAAPFKEEEK----SPVSAPKLP-KAQATSVIRHTADA 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 PAACFPTIQTPDCRLSDSREGEEQLLGHFET-LQDTHLTDSLLSTNLVSCQPCLHKSGGL : . . ... . :... .. . .: : .:. .. NP_005 QLCNHQTCPMKAASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCE----RNTVA 170 180 190 200 210 230 240 250 260 270 pF1KB7 LLTDKGQQAGWPGAVQT-----CSPKNYENDLPRKTTPLIS---VS---VPAPPVLCQMI . .:.. : . .: . : . . :.. . :.: :: :: ::.:::. NP_005 DVDEKASAALYDFSVPSSETVICRSQPAPVS-PQQKSVLVSPPAVSAGGVPPMPVICQMV 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB7 PVTGQSSMLPAFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPP : ::: . : .: : : : ::.: ::.::::.:.:: .. NP_005 P-------LPA--NNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQPVVQS 280 290 300 310 320 340 350 360 370 380 390 pF1KB7 PAPCAANVMAAGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSH : :.. ..:.: :.:::: : :. . .::.: :: :...:: ::: :::::::: NP_005 SKP---PVVSPNGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFKSSH 330 340 350 360 370 380 400 410 420 430 440 450 pF1KB7 LKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLT :::: :::::::::.::: ::...::::::::::::::::::::.::.:::::::::::: NP_005 LKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLT 390 400 410 420 430 440 460 470 480 490 pF1KB7 KHARRHMTTKKIPGWQAEVGKLNRIASAESPGSPLVSMPASA ::::::...::.:.:: ::.::: :: .: NP_005 KHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ 450 460 470 480 >>NP_001027453 (OMIM: 601878) Krueppel-like factor 10 is (469 aa) initn: 942 init1: 740 opt: 904 Z-score: 426.8 bits: 88.4 E(85289): 4.9e-17 Smith-Waterman score: 1046; 40.6% identity (61.8% similar) in 495 aa overlap (5-484:6-465) 10 20 30 40 50 pF1KB7 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMS-SWGQRSQKGDLLRIRPLTPV : : :: . .: : . :..:.::::::. :: :: . .: .. ::.::: NP_001 MEERMEMISERPK-ESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKK--YVENRPVTPV 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 SDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTA :: .. .. .:: :::.. ..:.::: ::. ::: :: .. . . . NP_001 SD---LSEEENLLPGTP----DFHTIPAFCLTPPYSPSDFEPSQ---VSNLMAPAPSTVH 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 TDVLQSSAVVARALSGGAERGLLGLEPV--PSSPCRAKGTSVIRHTGESPAACFPTIQTP :...: : :. :: :. : .:..:::::::... : NP_001 FKSLSDTAKPHIAAPFKEEEK----SPVSAPKLP-KAQATSVIRHTADAQLCNHQTCPMK 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 DCRLSDSREGEEQLLGHFET-LQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGW . . ... . :... .. . .: : .:. .. . .:.. : . NP_001 AASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCE----RNTVADVDEKASAALY 170 180 190 200 210 240 250 260 270 280 pF1KB7 PGAVQT-----CSPKNYENDLPRKTTPLIS---VS---VPAPPVLCQMIPVTGQSSMLPA .: . : . . :.. . :.: :: :: ::.:::.: ::: NP_001 DFSVPSSETVICRSQPAPVS-PQQKSVLVSPPAVSAGGVPPMPVICQMVP-------LPA 220 230 240 250 260 270 290 300 310 320 330 340 pF1KB7 FLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAA . : .: : : : ::.: ::.::::.:.:: .. : :.. NP_001 --NNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQPVVQSSKP---PVVSP 280 290 300 310 320 350 360 370 380 390 400 pF1KB7 GNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGE ..:.: :.:::: : :. . .::.: :: :...:: ::: :::::::::::: :::::: NP_001 NGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGE 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB7 KPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKK :::.::: ::...::::::::::::::::::::.::.::::::::::::::::::...:: NP_001 KPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKK 390 400 410 420 430 440 470 480 490 pF1KB7 IPGWQAEVGKLNRIASAESPGSPLVSMPASA .:.:: ::.::: :: .: NP_001 LPNWQMEVSKLNDIALPPTPAPTQ 450 460 >>NP_057079 (OMIM: 605328,612001) Krueppel-like factor 1 (288 aa) initn: 580 init1: 504 opt: 530 Z-score: 264.9 bits: 57.7 E(85289): 5.2e-08 Smith-Waterman score: 539; 45.5% identity (62.3% similar) in 220 aa overlap (301-495:71-287) 280 290 300 310 320 pF1KB7 QMIPVTGQSSMLPAFLKPPPQLSVGTVRPILAQAAPAPQPVFV--GPAVPQGAVMLVLPQ : : :::: :. : :. .. . :: NP_057 AATPTLPRVEERRDGKDSASLFVVARILADLNQQAPAPAPAERREGAAARKARTPCRLPP 50 60 70 80 90 100 330 340 350 360 370 pF1KB7 GALPPPAPCAANVMAAGNTK----------LLPL---APA----PVFITSSQNCVPQVDF : : .: : .. :: . : : .:: : . . ..:. NP_057 PAPEPTSPGAEGAAAAPPSPAWSEPEPEAGLEPEREPGPAGSGEPGLRQRVRRGRSRADL 110 120 130 140 150 160 380 390 400 410 420 430 pF1KB7 -SRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRT : .:.. : . ::.:.: :::::::::::::::.:: :::. :.:::::::::.:: :: NP_057 ESPQRKHKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQDCNKKFARSDELARHYRT 170 180 190 200 210 220 440 450 460 470 480 pF1KB7 HTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIASAES-----PG ::::::: ::.:..::::::::::::::: . . :: . : .: .: . . NP_057 HTGEKKFSCPICEKRFMRSDHLTKHARRHANFH--PGMLQRRGGGSRTGSLSDYSRSDAS 230 240 250 260 270 490 pF1KB7 SPLVSMPASA :: .: :::. NP_057 SPTIS-PASSP 280 >>NP_114124 (OMIM: 606139) Krueppel-like factor 16 [Homo (252 aa) initn: 528 init1: 496 opt: 526 Z-score: 263.7 bits: 57.3 E(85289): 6e-08 Smith-Waterman score: 541; 45.0% identity (65.1% similar) in 218 aa overlap (287-494:29-234) 260 270 280 290 300 310 pF1KB7 PLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPILAQAA--PAPQPVFVG .: :. ..: . . ..:: : .: : NP_114 MSAAVACVDYFAADVLMAISSGAVVHRGRPGPE-GAGPAAGLDVRAARREAASPGTPG 10 20 30 40 50 320 330 340 350 360 pF1KB7 PAVPQGAVMLVLPQGALPPPAPCAANVMAA--GNTKLLPLAPAPVFITS-----SQNCVP : : :. : :: : ::...: :. : . .:. .: :.. .: NP_114 PPPPPPAASGPGP-GAAAAPHLLAASILADLRGGPGAAPGGASPASSSSAASSPSSGRAP 60 70 80 90 100 110 370 380 390 400 410 420 pF1KB7 QVDFSRR-RNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSR . : ... : :: : :.:.::::::.::::::::.:: :.:.::::::::::::.: NP_114 GAAPSAAAKSHRCPFPDCAKAYYKSSHLKSHLRTHTGERPFACDWQGCDKKFARSDELAR 120 130 140 150 160 170 430 440 450 460 470 480 pF1KB7 HRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIASAESPGS :.:::::::.: ::.:..:: :::::.:::::: ::.. . : : .:.: : NP_114 HHRTHTGEKRFSCPLCSKRFTRSDHLAKHARRH------PGFHPD---LLRRPGARST-S 180 190 200 210 220 490 pF1KB7 PLVSMPASA : :.: : NP_114 PSDSLPCSLAGSPAPSPAPSPAPAGL 230 240 250 >>NP_001273747 (OMIM: 602903) Krueppel-like factor 5 iso (366 aa) initn: 499 init1: 465 opt: 509 Z-score: 254.6 bits: 56.2 E(85289): 1.9e-07 Smith-Waterman score: 509; 34.3% identity (53.8% similar) in 318 aa overlap (159-459:67-364) 130 140 150 160 170 180 pF1KB7 ARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRLSDSREGEE . : :.: : . . . . . NP_001 EGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIF----SHQSETTAPPPAPT 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB7 QLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQTCSPKNYE : : .: .. ..: : . .:. : . : :. ::. ..: : . NP_001 QALPEFTSIFSSHQTAAPEVNNIFIKQEL--PTPDLHLSVPTQQGHLYQLLNT--P---D 100 110 120 130 140 250 260 270 280 290 300 pF1KB7 NDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPA-----FLKPPPQLSVGTVRPILAQ :.: .:. .... . : .. ..: .: : :: . .: : NP_001 LDMPSSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPP-CTYTMPSQFLPQ 150 160 170 180 190 200 310 320 330 340 350 pF1KB7 AAP--APQPVFVGPAVP-QGAVMLVLPQGALPPPAPCA--ANVMAAGNTKLLPLAPAPVF : :.: :. : . : :: :. :::. : :. .: : .: : NP_001 QATYFPPSPPSSEPGSPDRQAEML---QNLTPPPSYAATIASKLAIHNPNLPTTLP---- 210 220 230 240 250 360 370 380 390 400 410 pF1KB7 ITSSQNCVP-------QVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSW ..::: : . :. .:: . :..::: :.: :::::::::::::::::..:.: NP_001 -VNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTW 260 270 280 290 300 310 420 430 440 450 460 470 pF1KB7 DGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAE .::: .:::::::.:: : ::: : : : ::.: : :::::. : .:: NP_001 EGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN 320 330 340 350 360 480 490 pF1KB7 VGKLNRIASAESPGSPLVSMPASA >>NP_619638 (OMIM: 609393) Krueppel-like factor 14 [Homo (323 aa) initn: 522 init1: 479 opt: 507 Z-score: 254.3 bits: 55.9 E(85289): 2e-07 Smith-Waterman score: 512; 47.5% identity (65.2% similar) in 181 aa overlap (285-461:114-279) 260 270 280 290 300 310 pF1KB7 TTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPP---QLSVGTVRPILAQAAP-APQP : : : : . . : . :: ::. NP_619 LAASVWADLRGSSGEGSWENSGEAPRASSGFSDPIPCSVQTPCSELAPASGAAAVCAPES 90 100 110 120 130 140 320 330 340 350 360 370 pF1KB7 VFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFITSSQNCVPQVD .::::.. : . : :: :.. ...: : ::: .. .: NP_619 SSDAPAVPSA------PAA---PGAPAASGGFSGGALGAGP-APAADQAPRRRSVTPA-- 150 160 170 180 190 380 390 400 410 420 430 pF1KB7 FSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRT ..:.. : :::: :.:.::::::.: ::::::.::.:.: :::::.:::::.:: :: NP_619 -AKRHQ--CPFPGCTKAYYKSSHLKSHQRTHTGERPFSCDWLDCDKKFTRSDELARHYRT 200 210 220 230 240 440 450 460 470 480 490 pF1KB7 HTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIASAESPGSPLVS :::::.: ::.: ..: :::::::::::: : NP_619 HTGEKRFSCPLCPKQFSRSDHLTKHARRHPTYHPDMIEYRGRRRTPRIDPPLTSEVESSA 250 260 270 280 290 300 pF1KB7 MPASA NP_619 SGSGPGPAPSFTTCL 310 320 >>NP_001721 (OMIM: 602903) Krueppel-like factor 5 isofor (457 aa) initn: 567 init1: 465 opt: 509 Z-score: 253.6 bits: 56.3 E(85289): 2.2e-07 Smith-Waterman score: 509; 34.3% identity (53.8% similar) in 318 aa overlap (159-459:158-455) 130 140 150 160 170 180 pF1KB7 ARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRLSDSREGEE . : :.: : . . . . . NP_001 EGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIF----SHQSETTAPPPAPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQTCSPKNYE : : .: .. ..: : . .:. : . : :. ::. ..: : . NP_001 QALPEFTSIFSSHQTAAPEVNNIFIKQEL--PTPDLHLSVPTQQGHLYQLLNT--P---D 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 NDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPA-----FLKPPPQLSVGTVRPILAQ :.: .:. .... . : .. ..: .: : :: . .: : NP_001 LDMPSSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPP-CTYTMPSQFLPQ 240 250 260 270 280 290 310 320 330 340 350 pF1KB7 AAP--APQPVFVGPAVP-QGAVMLVLPQGALPPPAPCA--ANVMAAGNTKLLPLAPAPVF : :.: :. : . : :: :. :::. : :. .: : .: : NP_001 QATYFPPSPPSSEPGSPDRQAEML---QNLTPPPSYAATIASKLAIHNPNLPTTLP---- 300 310 320 330 340 360 370 380 390 400 410 pF1KB7 ITSSQNCVP-------QVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSW ..::: : . :. .:: . :..::: :.: :::::::::::::::::..:.: NP_001 -VNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTW 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB7 DGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAE .::: .:::::::.:: : ::: : : : ::.: : :::::. : .:: NP_001 EGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN 410 420 430 440 450 480 490 pF1KB7 VGKLNRIASAESPGSPLVSMPASA 495 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:31:49 2016 done: Fri Nov 4 06:31:51 2016 Total Scan time: 11.690 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]