FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7274, 745 aa 1>>>pF1KB7274 745 - 745 aa - 745 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.6606+/-0.00111; mu= -5.3490+/- 0.066 mean_var=232.8262+/-47.450, 0's: 0 Z-trim(110.0): 17 B-trim: 4 in 1/51 Lambda= 0.084054 statistics sampled from 11278 (11285) to 11278 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.347), width: 16 Scan time: 2.560 The best scores are: opt bits E(32554) CCDS9946.1 PAPOLA gene_id:10914|Hs108|chr14 ( 745) 4839 600.3 3.4e-171 CCDS78202.1 PAPOLB gene_id:56903|Hs108|chr7 ( 637) 3527 441.2 2.3e-123 CCDS1863.1 PAPOLG gene_id:64895|Hs108|chr2 ( 736) 2817 355.1 2.2e-97 CCDS58334.1 PAPOLA gene_id:10914|Hs108|chr14 ( 285) 1847 237.4 2.4e-62 CCDS58335.1 PAPOLA gene_id:10914|Hs108|chr14 ( 238) 1343 176.2 5.1e-44 >>CCDS9946.1 PAPOLA gene_id:10914|Hs108|chr14 (745 aa) initn: 4839 init1: 4839 opt: 4839 Z-score: 3186.9 bits: 600.3 E(32554): 3.4e-171 Smith-Waterman score: 4839; 100.0% identity (100.0% similar) in 745 aa overlap (1-745:1-745) 10 20 30 40 50 60 pF1KB7 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 LGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 LFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 LFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 FPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 FPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 MKIAAMHVKRKQLHQLLPNHVLQKKKKHSTEGVKLTALNDSSLDLSMDSDNSMSVPSPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 MKIAAMHVKRKQLHQLLPNHVLQKKKKHSTEGVKLTALNDSSLDLSMDSDNSMSVPSPTS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 ATKTSPLNSSGSSQGRNSPAPAVTAASVTNIQATEVSVPQVNSSESSGGTSSESIPQTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 ATKTSPLNSSGSSQGRNSPAPAVTAASVTNIQATEVSVPQVNSSESSGGTSSESIPQTAT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 QPAISPPPKPTVSRVVSSTRLVNPPPRSSGNAATSGNAATKIPTPIVGVKRTSSPHKEES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 QPAISPPPKPTVSRVVSSTRLVNPPPRSSGNAATSGNAATKIPTPIVGVKRTSSPHKEES 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 PKKTKTEEDETSEDANCLALSGHDKTEAKEQLDTETSTTQSETIQTAASLLASQKTSSTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 PKKTKTEEDETSEDANCLALSGHDKTEAKEQLDTETSTTQSETIQTAASLLASQKTSSTD 670 680 690 700 710 720 730 740 pF1KB7 LSDIPALPANPIPVIKNSIKLRLNR ::::::::::::::::::::::::: CCDS99 LSDIPALPANPIPVIKNSIKLRLNR 730 740 >>CCDS78202.1 PAPOLB gene_id:56903|Hs108|chr7 (637 aa) initn: 3533 init1: 3253 opt: 3527 Z-score: 2328.1 bits: 441.2 E(32554): 2.3e-123 Smith-Waterman score: 3527; 86.1% identity (93.6% similar) in 625 aa overlap (1-625:2-624) 10 20 30 40 50 pF1KB7 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQ ::::::::: : :: ..::..::::::.::::::.:::.:::::.:::::::::::: CCDS78 MMPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 RRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCV ::::.: :::::::::::::::::.::::::::::::::::::::::::::::::::::: CCDS78 RRILVLEKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 APRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIP :: :::::::::::: :::::::::::::::::::::::::::::::::::::::::::: CCDS78 APSHVDRSDFFTSFYAKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 EDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSN ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: CCDS78 EDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSN 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB7 ILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPV ::::::::::::::::::::::::.:::::.:::::::.::::::::::.::: :::::: CCDS78 ILGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPV 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB7 WDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWS :::::::::::::::::::::::::::::::.::::::.:::::::::: :::::::::: CCDS78 WDPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB7 KLFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ ::::::.::::::::::::::: ::::.:::::::::::::::::::::::::::::::: CCDS78 KLFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB7 SFPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEV :::::::::: ::::::::::: .:: .::: ::.:::::::::::::::::.::::::. CCDS78 SFPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEM 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB7 DMKIAAMHVKRKQLHQLLPNHVLQKKKKHSTEGVKLTALNDSSLDLSMDSDNSMSVPSPT :::.:::..::.::::::.:::: :: ::::: .:: :::::.::: .::::::: : CCDS78 GMKITAMHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSST 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB7 SATKTSPLNSSGSSQGRNSPAPAVTAASVTNIQATEVSVPQVNSSESSGGTSSESIPQTA :. ::.:: :: :::::::: :: .:::.:::::: :. :::..:::: . .::::... CCDS78 STMKTGPLISS--SQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAV 550 560 570 580 590 600 610 620 630 640 650 pF1KB7 TQPAISPPPKPTVSRVVSSTRLVNPPPRSSGNAATSGNAATKIPTPIVGVKRTSSPHKEE .:::::: :: :.:::::: :.. : CCDS78 SQPAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL 600 610 620 630 >>CCDS1863.1 PAPOLG gene_id:64895|Hs108|chr2 (736 aa) initn: 2784 init1: 2669 opt: 2817 Z-score: 1861.8 bits: 355.1 E(32554): 2.2e-97 Smith-Waterman score: 2844; 61.2% identity (78.8% similar) in 747 aa overlap (13-745:12-736) 10 20 30 40 50 60 pF1KB7 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR .: :::::::::::::.::: : . :::::...:::::::.::::.. CCDS18 MKEMSANTVLDSQRQQKHYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNH 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA :...:::::::::::: ..::::::: ::. .:::::::::::::::::::::::::::: CCDS18 RLVVLGKLNNLVKEWISDVSESKNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE ::::.::::: ::..::: :. ...:::::.:::::::. :::::::..:::::.::: . CCDS18 PRHVERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTISD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNI .::::::: :..:::::::::::::::::::::::: ..:::::::.::::::..::::. CCDS18 NLDLRDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNM 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 LGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVW ::::::::::::::::::::::: :::::::::::::::::::::::::::: ::::::: CCDS18 LGFLGGVSWAMLVARTCQLYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVW 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSK ::::::::::::::::::::::::::::::.::: :::::::::::.::::: .:..::: CCDS18 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFKQGLAVTDEILQGKSDWSK 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB7 LFEAPNFFQKYKHYIVLLASAPTEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQS :.: :::::::.::::: ::: ::...::::::::::::.:::.::.::::::::::::: CCDS18 LLEPPNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNPQS 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB7 FPAPKENPDKEEFRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVD ::. ::. ... .:: .:..:...::.:....::::::::::::::::: : .:.. CCDS18 FPGNKEHHKDNNYVSMWFLGIIFRRVENAESVNIDLTYDIQSFTDTVYRQANNINMLKEG 420 430 440 450 460 470 490 500 510 520 530 pF1KB7 MKIAAMHVKRKQLHQLLPNHVLQKKKKHSTEGV---------KLTALNDSSLDLSMDSDN ::: : :::.::::. :: ..::::::.: : : .:..: :: : :.:: CCDS18 MKIEATHVKKKQLHHYLPAEILQKKKKQSLSDVNRSSGGLQSKRLSLDSSCLDSSRDTDN 480 490 500 510 520 530 540 550 560 570 580 pF1KB7 SMSVPSPTSATKTSPLNSSGSSQGRNS--PAPAVTAASVTNIQATEVSVPQVNSSESSGG . ::.: . :: : : .. ::: :: ... .. : .:.: . : CCDS18 GTPFNSPASKSD-SP--SVGETE-RNSAEPAAVIVEKPLSVPPAQGLSIPVI-------G 540 550 560 570 580 590 600 610 620 630 640 pF1KB7 TSSESIPQTATQPAISPPPKPTVSRVVSSTRLVNPPPRSSGNAATSG-NAATKIPTPIVG .. .: .:.. :.. : .:.: : :...: ..:. .: . :: :: CCDS18 AKVDSTVKTVSPPTVCTIPT-VVGRNVIP-RITTPHNPAQGQPHLNGMSNITKTVTP--- 590 600 610 620 630 640 650 660 670 680 690 700 pF1KB7 VKRTSSPHKEESPKKTKTEEDETSEDANCLALSGHDKTEAKEQLDTETSTTQSETIQTAA ::. :: . .::. : : : . .: :.:. ... .:.. . CCDS18 -KRSHSPSIDGTPKRLKDVEKFIR-----LESTFKDPRTAEERKRKSVDAIGGESMPIPT 650 660 670 680 690 710 720 730 740 pF1KB7 SLLASQKT-SSTDLSDIPA-LPANPIPVIKNSIKLRLNR . .: : .: : . .::: : ::::::.: ::: CCDS18 IDTSRKKRLPSKELPDSSSPVPANNIRVIKNSIRLTLNR 700 710 720 730 >>CCDS58334.1 PAPOLA gene_id:10914|Hs108|chr14 (285 aa) initn: 1847 init1: 1847 opt: 1847 Z-score: 1232.7 bits: 237.4 E(32554): 2.4e-62 Smith-Waterman score: 1847; 100.0% identity (100.0% similar) in 279 aa overlap (1-279:1-279) 10 20 30 40 50 60 pF1KB7 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVW ::::::::::::::::::::::::::::::::::::::: CCDS58 LGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWYVFRLY 250 260 270 280 310 320 330 340 350 360 pF1KB7 DPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSK >>CCDS58335.1 PAPOLA gene_id:10914|Hs108|chr14 (238 aa) initn: 1336 init1: 1336 opt: 1343 Z-score: 903.7 bits: 176.2 E(32554): 5.1e-44 Smith-Waterman score: 1343; 90.1% identity (94.8% similar) in 232 aa overlap (1-230:1-231) 10 20 30 40 50 60 pF1KB7 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MPFPVTTQGSQQTQPPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPE 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 DLDLRDDSLLKNLDIRCIRSLNGCRVTDE--ILHLVPNIDNFRLTLRAIKLWAKRHNIYS ::::::::::::::::::::::: : .:... .:. : .. ..::. CCDS58 DLDLRDDSLLKNLDIRCIRSLNGMRKPTSFCVLQFLSDISCFYTSF-VLKLFIAILLTQ 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 NILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLP 745 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 22:12:55 2016 done: Sat Nov 5 22:12:55 2016 Total Scan time: 2.560 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]