FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7276, 382 aa 1>>>pF1KB7276 382 - 382 aa - 382 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0365+/-0.00111; mu= 13.2422+/- 0.066 mean_var=73.3498+/-14.578, 0's: 0 Z-trim(102.4): 29 B-trim: 0 in 0/49 Lambda= 0.149753 statistics sampled from 6907 (6919) to 6907 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.569), E-opt: 0.2 (0.213), width: 16 Scan time: 2.630 The best scores are: opt bits E(32554) CCDS6296.1 ATP6V1C1 gene_id:528|Hs108|chr8 ( 382) 2470 543.2 1.4e-154 CCDS1674.1 ATP6V1C2 gene_id:245973|Hs108|chr2 ( 381) 1625 360.7 1.3e-99 CCDS42653.1 ATP6V1C2 gene_id:245973|Hs108|chr2 ( 427) 1118 251.2 1.3e-66 >>CCDS6296.1 ATP6V1C1 gene_id:528|Hs108|chr8 (382 aa) initn: 2470 init1: 2470 opt: 2470 Z-score: 2888.7 bits: 543.2 E(32554): 1.4e-154 Smith-Waterman score: 2470; 100.0% identity (100.0% similar) in 382 aa overlap (1-382:1-382) 10 20 30 40 50 60 pF1KB7 MTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LDAFVEGVVKKVAQYMADVLEDSKDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 LDAFVEGVVKKVAQYMADVLEDSKDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 ISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 YLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 YLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 ARENKFIVRDFQYNEEEMKADKEEMNRLSTDKKKQFGPLVRWLKVNFSEAFIAWIHVKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 ARENKFIVRDFQYNEEEMKADKEEMNRLSTDKKKQFGPLVRWLKVNFSEAFIAWIHVKAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 RVFVESVLRYGLPVNFQAMLLQPNKKTLKKLREVLHELYKHLDSSAAAIIDAPMDIPGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 RVFVESVLRYGLPVNFQAMLLQPNKKTLKKLREVLHELYKHLDSSAAAIIDAPMDIPGLN 310 320 330 340 350 360 370 380 pF1KB7 LSQQEYYPYVYYKIDCNLLEFK :::::::::::::::::::::: CCDS62 LSQQEYYPYVYYKIDCNLLEFK 370 380 >>CCDS1674.1 ATP6V1C2 gene_id:245973|Hs108|chr2 (381 aa) initn: 1510 init1: 1341 opt: 1625 Z-score: 1902.1 bits: 360.7 E(32554): 1.3e-99 Smith-Waterman score: 1625; 62.3% identity (90.3% similar) in 382 aa overlap (1-380:1-381) 10 20 30 40 50 60 pF1KB7 MTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAK :.:::::::::.: :. :.....:::.: :. ..:: :::.:::::: ::::::::.: CCDS16 MSEFWLISAPGDKENLQALERMNTVTSKSN-LSYNTKFAIPDFKVGTLDSLVGLSDELGK 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 LDAFVEGVVKKVAQYMADVLEDSKDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKN ::.:.:......:: ...:.:::: ::::.::::::::....:.:.:::::::.:: : . CCDS16 LDTFAESLIRRMAQSVVEVMEDSKGKVQEHLLANGVDLTSFVTHFEWDMAKYPVKQPLVS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 ISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSE . . ::: ..::. :::::..:::.:: ::.:::.:. :.:.::.:..::.:.::::::: CCDS16 VVDTIAKQLAQIEMDLKSRTAAYNTLKTNLENLEKKSMGNLFTRTLSDIVSKEDFVLDSE 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 YLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHK :::::::.::: :...: : ::.:..::::::.....::... : .::::::...::. : CCDS16 YLVTLLVIVPKPNYSQWQKTYESLSDMVVPRSTKLITEDKEGGLFTVTLFRKVIEDFKTK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 ARENKFIVRDFQYNEEEMKADKEEMNRLSTDKKKQFGPLVRWLKVNFSEAFIAWIHVKAL :.:::: ::.: :.:.:.. ..::: :: .:::.:.:::.::::::::::::::::.::: CCDS16 AKENKFTVREFYYDEKEIEREREEMARLLSDKKQQYGPLLRWLKVNFSEAFIAWIHIKAL 240 250 260 270 280 290 310 320 330 340 350 pF1KB7 RVFVESVLRYGLPVNFQAMLLQPNKKT-LKKLREVLHELYKHLDSSAA-AIIDAPMDIPG ::::::::::::::::::.::::.::. :.:::::. ...::: :: .:.:: ..::: CCDS16 RVFVESVLRYGLPVNFQAVLLQPHKKSSTKRLREVLNSVFRHLDEVAATSILDASVEIPG 300 310 320 330 340 350 360 370 380 pF1KB7 LNLSQQEYYPYVYYKIDCNLLEFK :.:..:.:.::::..:: .::. CCDS16 LQLNNQDYFPYVYFHIDLSLLD 360 370 380 >>CCDS42653.1 ATP6V1C2 gene_id:245973|Hs108|chr2 (427 aa) initn: 1496 init1: 1019 opt: 1118 Z-score: 1309.3 bits: 251.2 E(32554): 1.3e-66 Smith-Waterman score: 1460; 55.6% identity (80.2% similar) in 414 aa overlap (1-366:1-413) 10 20 30 40 50 60 pF1KB7 MTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAK :.:::::::::.: :. :.....:::.: :. ..:: :::.:::::: ::::::::.: CCDS42 MSEFWLISAPGDKENLQALERMNTVTSKSN-LSYNTKFAIPDFKVGTLDSLVGLSDELGK 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 LDAFVEGVVKKVAQYMADVLEDSKDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKN ::.:.:......:: ...:.:::: ::::.::::::::....:.:.:::::::.:: : . CCDS42 LDTFAESLIRRMAQSVVEVMEDSKGKVQEHLLANGVDLTSFVTHFEWDMAKYPVKQPLVS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 ISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSE . . ::: ..::. :::::..:::.:: ::.:::.:. :.:.::.:..::.:.::::::: CCDS42 VVDTIAKQLAQIEMDLKSRTAAYNTLKTNLENLEKKSMGNLFTRTLSDIVSKEDFVLDSE 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 YLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHK :::::::.::: :...: : ::.:..::::::.....::... : .::::::...::. : CCDS42 YLVTLLVIVPKPNYSQWQKTYESLSDMVVPRSTKLITEDKEGGLFTVTLFRKVIEDFKTK 180 190 200 210 220 230 250 260 270 pF1KB7 ARENKFIVRDFQYNEEEMKADKEEMNRLSTDKKKQF------------------------ :.:::: ::.: :.:.:.. ..::: :: .:::.:. CCDS42 AKENKFTVREFYYDEKEIEREREEMARLLSDKKQQYQTSCVALKKGSSTFPDHKVKVTPL 240 250 260 270 280 290 280 290 300 310 pF1KB7 ----------------------GPLVRWLKVNFSEAFIAWIHVKALRVFVESVLRYGLPV :::.::::::::::::::::.::::::::::::::::: CCDS42 GNPDRPAAGQTDRERESEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPV 300 310 320 330 340 350 320 330 340 350 360 370 pF1KB7 NFQAMLLQPNKKT-LKKLREVLHELYKHLDSSAA-AIIDAPMDIPGLNLSQQEYYPYVYY ::::.::::.::. :.:::::. ...::: :: .:.:: ..::::.:..:.: CCDS42 NFQAVLLQPHKKSSTKRLREVLNSVFRHLDEVAATSILDASVEIPGLQLNNQDYFPYVYF 360 370 380 390 400 410 380 pF1KB7 KIDCNLLEFK CCDS42 HIDLSLLD 420 382 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:33:23 2016 done: Sat Nov 5 21:33:24 2016 Total Scan time: 2.630 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]