FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7282, 705 aa
1>>>pF1KB7282 705 - 705 aa - 705 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9679+/-0.00103; mu= 3.9399+/- 0.062
mean_var=195.6169+/-39.113, 0's: 0 Z-trim(110.5): 26 B-trim: 9 in 1/52
Lambda= 0.091700
statistics sampled from 11648 (11666) to 11648 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.358), width: 16
Scan time: 4.110
The best scores are: opt bits E(32554)
CCDS9108.1 RFX4 gene_id:5992|Hs108|chr12 ( 641) 3348 455.8 8.9e-128
CCDS9106.1 RFX4 gene_id:5992|Hs108|chr12 ( 735) 3348 455.9 9.9e-128
CCDS55880.1 RFX4 gene_id:5992|Hs108|chr12 ( 744) 3348 455.9 1e-127
CCDS5113.1 RFX6 gene_id:222546|Hs108|chr6 ( 928) 623 95.4 4e-19
>>CCDS9108.1 RFX4 gene_id:5992|Hs108|chr12 (641 aa)
initn: 3339 init1: 3339 opt: 3348 Z-score: 2407.5 bits: 455.8 E(32554): 8.9e-128
Smith-Waterman score: 3839; 91.4% identity (93.3% similar) in 641 aa overlap (98-705:1-641)
70 80 90 100 110 120
pF1KB7 NYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFG--KIIRQQFPQLTTRRLGTRGQS
.: :.:: ... . :. .: .:. .
CCDS91 MNWAAFGGSEFFIPEGIQIDSRCPLSRNIT
10 20 30
130 140 150 160 170 180
pF1KB7 K-YHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPEFPNV
. ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 EWYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPEFPNV
40 50 60 70 80 90
190 200 210
pF1KB7 KDLNLPASLPEEKVSTFIMMYRTHCQRIL------------------------------G
::::::::::::::::::::::::::::: :
CCDS91 KDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLG
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB7 SSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 SSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPEN
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB7 LRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 LRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLY
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB7 TMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 TMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVA
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB7 QQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 QQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAM
340 350 360 370 380 390
460 470 480 490 500 510
pF1KB7 KGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 KGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTT
400 410 420 430 440 450
520 530 540 550 560 570
pF1KB7 GAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGYTGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 GAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGYTGSY
460 470 480 490 500 510
580 590 600 610 620 630
pF1KB7 NYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLMSSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 NYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLMSSTP
520 530 540 550 560 570
640 650 660 670 680 690
pF1KB7 RLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFPGFAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 RLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFPGFAY
580 590 600 610 620 630
700
pF1KB7 INGEASTGWAK
:::::::::::
CCDS91 INGEASTGWAK
640
>>CCDS9106.1 RFX4 gene_id:5992|Hs108|chr12 (735 aa)
initn: 3339 init1: 3339 opt: 3348 Z-score: 2406.6 bits: 455.9 E(32554): 9.9e-128
Smith-Waterman score: 4694; 95.9% identity (95.9% similar) in 735 aa overlap (1-705:1-735)
10 20 30 40 50 60
pF1KB7 MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 TLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 TRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 TRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPE
130 140 150 160 170 180
190 200 210
pF1KB7 FPNVKDLNLPASLPEEKVSTFIMMYRTHCQRIL---------------------------
:::::::::::::::::::::::::::::::::
CCDS91 FPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHML
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB7 ---GSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 PVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHD
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB7 LPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 LPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITK
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB7 QTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 QTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB7 KKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 KKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANEL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB7 MRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 MRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTG
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB7 LSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 LSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGY
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB7 TGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 TGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLM
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB7 SSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 SSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFP
670 680 690 700 710 720
700
pF1KB7 GFAYINGEASTGWAK
:::::::::::::::
CCDS91 GFAYINGEASTGWAK
730
>>CCDS55880.1 RFX4 gene_id:5992|Hs108|chr12 (744 aa)
initn: 3339 init1: 3339 opt: 3348 Z-score: 2406.6 bits: 455.9 E(32554): 1e-127
Smith-Waterman score: 4601; 95.9% identity (95.9% similar) in 723 aa overlap (13-705:22-744)
10 20 30 40 50
pF1KB7 MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNR
:::::::::::::::::::::::::::::::::::::::
CCDS55 MIKRRAHPGAGGDRTRPRRRRSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 ASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 PQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 PQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPR
130 140 150 160 170 180
180 190 200 210
pF1KB7 SKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRIL------------------
::::::::::::::::::::::::::::::::::::::::::
CCDS55 SKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHF
190 200 210 220 230 240
220 230 240 250 260
pF1KB7 ------------GSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLD
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 WQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLD
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB7 EWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 EWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWR
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB7 NVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 NVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVK
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB7 VAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESL
430 440 450 460 470 480
450 460 470 480 490 500
pF1KB7 HCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 HCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPV
490 500 510 520 530 540
510 520 530 540 550 560
pF1KB7 SNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPV
550 560 570 580 590 600
570 580 590 600 610 620
pF1KB7 YPHREEHGYTGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 YPHREEHGYTGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSP
610 620 630 640 650 660
630 640 650 660 670 680
pF1KB7 TSRMEPCLMSSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 TSRMEPCLMSSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNS
670 680 690 700 710 720
690 700
pF1KB7 EYEHMQHFPGFAYINGEASTGWAK
::::::::::::::::::::::::
CCDS55 EYEHMQHFPGFAYINGEASTGWAK
730 740
>>CCDS5113.1 RFX6 gene_id:222546|Hs108|chr6 (928 aa)
initn: 983 init1: 605 opt: 623 Z-score: 456.8 bits: 95.4 E(32554): 4e-19
Smith-Waterman score: 1261; 36.8% identity (61.1% similar) in 679 aa overlap (25-631:85-763)
10 20 30 40 50
pF1KB7 MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRA--
::.. ..: : ..... .:..
CCDS51 GEQGGGEKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAADQYLSQKKTITQIV
60 70 80 90 100 110
60 70 80 90 100 110
pF1KB7 -SKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQF
.: ..: ::::::::: . ::::.:: :: ::::::.:. .:. ::.::: :::.:
CCDS51 KDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKF
120 130 140 150 160 170
120 130 140 150 160 170
pF1KB7 PQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPR
: ::::::::::.::::::::..:::: :: .:: :: . : . :. . : ::
CCDS51 PLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLS
180 190 200 210 220 230
180 190 200 210
pF1KB7 SKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILGSS---------------
:: ::::::::... : . . ..::.:.::::.:::: :: ..
CCDS51 SKTGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHF
240 250 260 270 280 290
220 230 240 250 260
pF1KB7 ---------------TVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLD
....: ::::::::... ::.:...: .:.:: ::.:::. .
CCDS51 WQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWE
300 310 320 330 340 350
270 280 290 300 310 320
pF1KB7 EWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWR
.:. .:..::: : . :. . ::: . :.::::. :: : .: .. . .. .:. : .
CCDS51 QWVVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIE
360 370 380 390 400 410
330 340 350 360 370
pF1KB7 NVDLNSITKQTLYTMEDSRDEHRKLITQ-----LYQEFDHLLEEQSPIESYIEWLDTMVD
:::::: .:.: :. : : . . :. ..::. ::.... .:..::::::.:.
CCDS51 RVDLNSIGSQALLTISGSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVE
420 430 440 450 460 470
380 390 400 410 420 430
pF1KB7 RCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLY
. :.:.. . :::: ::.::: :: ::.::....::..: ::::::::....:.:.:
CCDS51 QRVIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILL
480 490 500 510 520 530
440 450 460 470 480 490
pF1KB7 LLESLHCQERANELM----RAMKG-EGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATS
.:. ... .::. . ::. ..: : : . . . : . .:. .
CCDS51 AMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESH
540 550 560 570 580 590
500 510 520 530
pF1KB7 VE---VPPPSS------PVSN--PSPEYTGLSTTGAMQSYTWS---LTYTVTTAAGSPAE
:: .: ::: :. . :. . .. :: :. . .: .. : .: .
CCDS51 VETTYLPLPSSQPGGLGPALHQFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGS
600 610 620 630 640 650
540 550 560 570 580
pF1KB7 NSQQLPCM-RNTHV------PSSSVTHRIPVYPH--REEHG-YTGSYNYGSYGNQHPHPM
.: : : : :: :. :.:: . .: :. : :: . .::
CCDS51 VINQGPMAGRPPSVGPVLSAPSHCSTYPEPIYPTLPQANHDFYSTSSNYQTVFRAQPHST
660 670 680 690 700 710
590 600 610 620 630 640
pF1KB7 QSQYPA-LPHDTAIS---GPLHYAPYHRSSAQYPFNS-PTSRMEPCLMSSTPRLHPTPVT
.. :: : .. : . : : :.:: : : . : :..
CCDS51 SGLYPHHTEHGRCMAWTEQQLSRDFFSGSCAGSPYNSRPPSSYGPSLQAQDSHNMQFLNT
720 730 740 750 760 770
650 660 670 680 690 700
pF1KB7 PRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTG
CCDS51 GSFNFLSNTGAASCQGATLPPNSPNGYYGSNINYPESHRLGSMVNQHVSVISSIRSLPPY
780 790 800 810 820 830
705 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 06:34:05 2016 done: Fri Nov 4 06:34:06 2016
Total Scan time: 4.110 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]