Result of FASTA (omim) for pF1KB7282
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7282, 705 aa
  1>>>pF1KB7282 705 - 705 aa - 705 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.3703+/-0.000409; mu= 1.5671+/- 0.026
 mean_var=217.2560+/-44.750, 0's: 0 Z-trim(118.6): 56  B-trim: 548 in 2/58
 Lambda= 0.087014
 statistics sampled from 31687 (31746) to 31687 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.372), width:  16
 Scan time: 12.040

The best scores are:                                      opt bits E(85289)
NP_115880 (OMIM: 603958) transcription factor RFX4 ( 641) 3348 433.5 1.2e-120
NP_998759 (OMIM: 603958) transcription factor RFX4 ( 735) 3348 433.6 1.3e-120
NP_001193620 (OMIM: 603958) transcription factor R ( 744) 3348 433.6 1.4e-120
XP_011533891 (OMIM: 612659,615710) PREDICTED: DNA- ( 892) 1114 153.2 4.2e-36
NP_775831 (OMIM: 612659,615710) DNA-binding protei ( 928)  623 91.6 1.5e-17
XP_016865966 (OMIM: 612659,615710) PREDICTED: DNA- ( 802)  582 86.4 4.8e-16
XP_006716910 (OMIM: 601337) PREDICTED: transcripti ( 492)  549 82.1 5.7e-15
XP_016870491 (OMIM: 601337) PREDICTED: transcripti ( 501)  549 82.1 5.8e-15
XP_016870490 (OMIM: 601337) PREDICTED: transcripti ( 724)  376 60.5 2.7e-08
XP_011516302 (OMIM: 601337) PREDICTED: transcripti ( 745)  376 60.5 2.8e-08
XP_016882597 (OMIM: 142765) PREDICTED: DNA-binding ( 653)  374 60.2   3e-08
NP_602309 (OMIM: 142765) DNA-binding protein RFX2  ( 698)  374 60.2 3.1e-08
NP_002909 (OMIM: 600006) MHC class II regulatory f ( 979)  370 59.8 5.8e-08
XP_011526472 (OMIM: 600006) PREDICTED: MHC class I ( 980)  370 59.8 5.8e-08
XP_011526471 (OMIM: 600006) PREDICTED: MHC class I ( 980)  370 59.8 5.8e-08
XP_011526469 (OMIM: 600006) PREDICTED: MHC class I (1089)  370 59.8 6.4e-08
XP_011526468 (OMIM: 600006) PREDICTED: MHC class I (1089)  370 59.8 6.4e-08
XP_011526467 (OMIM: 600006) PREDICTED: MHC class I (1089)  370 59.8 6.4e-08
NP_001269046 (OMIM: 601337) transcription factor R ( 413)  347 56.7 2.1e-07
XP_016882596 (OMIM: 142765) PREDICTED: DNA-binding ( 678)  348 56.9 2.9e-07
XP_011526474 (OMIM: 142765) PREDICTED: DNA-binding ( 687)  348 56.9   3e-07
XP_011526473 (OMIM: 142765) PREDICTED: DNA-binding ( 723)  348 57.0 3.1e-07
NP_000626 (OMIM: 142765) DNA-binding protein RFX2  ( 723)  348 57.0 3.1e-07
XP_011516303 (OMIM: 601337) PREDICTED: transcripti ( 687)  347 56.8 3.2e-07
NP_002910 (OMIM: 601337) transcription factor RFX3 ( 707)  347 56.8 3.3e-07
XP_011526470 (OMIM: 600006) PREDICTED: MHC class I ( 991)  350 57.3 3.4e-07
NP_001269045 (OMIM: 601337) transcription factor R ( 749)  347 56.8 3.5e-07
NP_602304 (OMIM: 601337) transcription factor RFX3 ( 749)  347 56.8 3.5e-07
XP_016870489 (OMIM: 601337) PREDICTED: transcripti ( 770)  347 56.9 3.6e-07
XP_006716908 (OMIM: 601337) PREDICTED: transcripti ( 770)  347 56.9 3.6e-07
XP_006716907 (OMIM: 601337) PREDICTED: transcripti ( 770)  347 56.9 3.6e-07
XP_011516300 (OMIM: 601337) PREDICTED: transcripti ( 770)  347 56.9 3.6e-07
XP_011516301 (OMIM: 601337) PREDICTED: transcripti ( 770)  347 56.9 3.6e-07
XP_006716906 (OMIM: 601337) PREDICTED: transcripti ( 770)  347 56.9 3.6e-07
XP_006716903 (OMIM: 601337) PREDICTED: transcripti ( 780)  347 56.9 3.6e-07


>>NP_115880 (OMIM: 603958) transcription factor RFX4 iso  (641 aa)
 initn: 3339 init1: 3339 opt: 3348  Z-score: 2287.0  bits: 433.5 E(85289): 1.2e-120
Smith-Waterman score: 3839; 91.4% identity (93.3% similar) in 641 aa overlap (98-705:1-641)

        70        80        90       100         110       120     
pF1KB7 NYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFG--KIIRQQFPQLTTRRLGTRGQS
                                     .: :.::  ...  .  :. .:   .:. .
NP_115                               MNWAAFGGSEFFIPEGIQIDSRCPLSRNIT
                                             10        20        30

          130       140       150       160       170       180    
pF1KB7 K-YHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPEFPNV
       . ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EWYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPEFPNV
               40        50        60        70        80        90

          190       200       210                                  
pF1KB7 KDLNLPASLPEEKVSTFIMMYRTHCQRIL------------------------------G
       :::::::::::::::::::::::::::::                              :
NP_115 KDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLG
              100       110       120       130       140       150

          220       230       240       250       260       270    
pF1KB7 SSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPEN
              160       170       180       190       200       210

          280       290       300       310       320       330    
pF1KB7 LRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLY
              220       230       240       250       260       270

          340       350       360       370       380       390    
pF1KB7 TMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVA
              280       290       300       310       320       330

          400       410       420       430       440       450    
pF1KB7 QQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 QQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAM
              340       350       360       370       380       390

          460       470       480       490       500       510    
pF1KB7 KGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTT
              400       410       420       430       440       450

          520       530       540       550       560       570    
pF1KB7 GAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGYTGSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGYTGSY
              460       470       480       490       500       510

          580       590       600       610       620       630    
pF1KB7 NYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLMSSTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 NYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLMSSTP
              520       530       540       550       560       570

          640       650       660       670       680       690    
pF1KB7 RLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFPGFAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFPGFAY
              580       590       600       610       620       630

          700     
pF1KB7 INGEASTGWAK
       :::::::::::
NP_115 INGEASTGWAK
              640 

>>NP_998759 (OMIM: 603958) transcription factor RFX4 iso  (735 aa)
 initn: 3339 init1: 3339 opt: 3348  Z-score: 2286.1  bits: 433.6 E(85289): 1.3e-120
Smith-Waterman score: 4694; 95.9% identity (95.9% similar) in 735 aa overlap (1-705:1-735)

               10        20        30        40        50        60
pF1KB7 MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 TLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 TLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 TRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 TRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPE
              130       140       150       160       170       180

              190       200       210                              
pF1KB7 FPNVKDLNLPASLPEEKVSTFIMMYRTHCQRIL---------------------------
       :::::::::::::::::::::::::::::::::                           
NP_998 FPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHML
              190       200       210       220       230       240

              220       230       240       250       260       270
pF1KB7 ---GSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHD
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 PVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHD
              250       260       270       280       290       300

              280       290       300       310       320       330
pF1KB7 LPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 LPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITK
              310       320       330       340       350       360

              340       350       360       370       380       390
pF1KB7 QTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 QTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSL
              370       380       390       400       410       420

              400       410       420       430       440       450
pF1KB7 KKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 KKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANEL
              430       440       450       460       470       480

              460       470       480       490       500       510
pF1KB7 MRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 MRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTG
              490       500       510       520       530       540

              520       530       540       550       560       570
pF1KB7 LSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 LSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGY
              550       560       570       580       590       600

              580       590       600       610       620       630
pF1KB7 TGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 TGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLM
              610       620       630       640       650       660

              640       650       660       670       680       690
pF1KB7 SSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 SSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFP
              670       680       690       700       710       720

              700     
pF1KB7 GFAYINGEASTGWAK
       :::::::::::::::
NP_998 GFAYINGEASTGWAK
              730     

>>NP_001193620 (OMIM: 603958) transcription factor RFX4   (744 aa)
 initn: 3339 init1: 3339 opt: 3348  Z-score: 2286.0  bits: 433.6 E(85289): 1.4e-120
Smith-Waterman score: 4601; 95.9% identity (95.9% similar) in 723 aa overlap (13-705:22-744)

                        10        20        30        40        50 
pF1KB7          MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNR
                            :::::::::::::::::::::::::::::::::::::::
NP_001 MIKRRAHPGAGGDRTRPRRRRSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNR
               10        20        30        40        50        60

              60        70        80        90       100       110 
pF1KB7 ASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQF
               70        80        90       100       110       120

             120       130       140       150       160       170 
pF1KB7 PQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPR
              130       140       150       160       170       180

             180       190       200       210                     
pF1KB7 SKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRIL------------------
       ::::::::::::::::::::::::::::::::::::::::::                  
NP_001 SKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHF
              190       200       210       220       230       240

                       220       230       240       250       260 
pF1KB7 ------------GSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLD
                   ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLD
              250       260       270       280       290       300

             270       280       290       300       310       320 
pF1KB7 EWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWR
              310       320       330       340       350       360

             330       340       350       360       370       380 
pF1KB7 NVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVK
              370       380       390       400       410       420

             390       400       410       420       430       440 
pF1KB7 VAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESL
              430       440       450       460       470       480

             450       460       470       480       490       500 
pF1KB7 HCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPV
              490       500       510       520       530       540

             510       520       530       540       550       560 
pF1KB7 SNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPV
              550       560       570       580       590       600

             570       580       590       600       610       620 
pF1KB7 YPHREEHGYTGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPHREEHGYTGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSP
              610       620       630       640       650       660

             630       640       650       660       670       680 
pF1KB7 TSRMEPCLMSSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSRMEPCLMSSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNS
              670       680       690       700       710       720

             690       700     
pF1KB7 EYEHMQHFPGFAYINGEASTGWAK
       ::::::::::::::::::::::::
NP_001 EYEHMQHFPGFAYINGEASTGWAK
              730       740    

>>XP_011533891 (OMIM: 612659,615710) PREDICTED: DNA-bind  (892 aa)
 initn: 1167 init1: 452 opt: 1114  Z-score: 769.2  bits: 153.2 E(85289): 4.2e-36
Smith-Waterman score: 1150; 35.6% identity (61.5% similar) in 654 aa overlap (25-631:85-727)

                     10        20        30        40        50    
pF1KB7       MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRA--
                                     ::..  ..: :  .....   .:..     
XP_011 GEQGGGEKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAADQYLSQKKTITQIV
           60        70        80        90       100       110    

              60        70        80        90       100       110 
pF1KB7 -SKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQF
        .: ..:  ::::::::: . ::::.::  :: ::::::.:.  .:. ::.::: :::.:
XP_011 KDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKF
          120       130       140       150       160       170    

             120       130       140       150        160       170
pF1KB7 PQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETG-KKEVSKQTVAYSP
       : ::::::::::.::::::::..:::: ::  .:: :: .  : .  :.::.   . :  
XP_011 PLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEVDTLIMMY--
          180       190       200       210       220       230    

              180       190       200           210       220      
pF1KB7 RSKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRT----HCQRILGSSTVVNIVGVCD
       ...   .:    :. . :.      :... :.. .      :   .: . ....:  :::
XP_011 KTHCQCILD---NAINGNF------EEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCD
            240                250       260       270       280   

        230       240       250       260       270       280      
pF1KB7 SILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRF
       :::::... ::.:...: .:.::   ::.:::. ..:.  .:..::: : . :. . :::
XP_011 SILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTDKKIPIVRRF
           290       300       310       320       330       340   

        290       300       310       320       330       340      
pF1KB7 SQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRKL
        . :.::::. :: : .: .. .  .. .:. : . :::::: .:.: :.  : : .  .
XP_011 VSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERVDLNSIGSQALLTISGSTDTESGI
           350       360       370       380       390       400   

             350       360       370       380       390       400 
pF1KB7 ITQ-----LYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMW
        :.     ..::.  ::.... .:..::::::.:.. :.:.. .   :::: ::.::: :
XP_011 YTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGRSLKKRAQDFLLKW
           410       420       430       440       450       460   

             410       420       430       440       450           
pF1KB7 SCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELM----RAMKG-
       : ::.::....::..: ::::::::....:.:.:  .:.   ... .::.    . ::. 
XP_011 SFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNS
           470       480       490       500       510       520   

        460       470       480       490                500       
pF1KB7 EGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVE---VPPPSS------PVSN--PS
       ..: :           :  . . . : . .:. . ::   .: :::      :. .  :.
XP_011 DASKAAFTASPSSCFLANRNKGSMVSSDAVKNESHVETTYLPLPSSQPGGLGPALHQFPA
           530       540       550       560       570       580   

         510       520          530       540        550           
pF1KB7 PEYTGLSTTGAMQSYTWS---LTYTVTTAAGSPAENSQQLPCM-RNTHV------PSSSV
        .  ..  :: :.    .   .:  .. : .: .   .: :   :   :      ::   
XP_011 GNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCS
           590       600       610       620       630       640   

         560          570       580       590        600           
pF1KB7 THRIPVYPH--REEHG-YTGSYNYGSYGNQHPHPMQSQYPA-LPHDTAIS---GPLHYAP
       :.  :.::   . .:  :. : :: .    .::  .. ::    :   ..     :    
XP_011 TYPEPIYPTLPQANHDFYSTSSNYQTVFRAQPHSTSGLYPHHTEHGRCMAWTEQQLSRDF
           650       660       670       680       690       700   

      610       620        630       640       650       660       
pF1KB7 YHRSSAQYPFNS-PTSRMEPCLMSSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGN
       .  : :  :.:: : : . : :..                                    
XP_011 FSGSCAGSPYNSRPPSSYGPSLQAQDSHNMQFLNTGSFNFLSNTGAASCQGATLPPNSPN
           710       720       730       740       750       760   

>>NP_775831 (OMIM: 612659,615710) DNA-binding protein RF  (928 aa)
 initn: 983 init1: 605 opt: 623  Z-score: 435.9  bits: 91.6 E(85289): 1.5e-17
Smith-Waterman score: 1261; 36.8% identity (61.1% similar) in 679 aa overlap (25-631:85-763)

                     10        20        30        40        50    
pF1KB7       MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRA--
                                     ::..  ..: :  .....   .:..     
NP_775 GEQGGGEKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAADQYLSQKKTITQIV
           60        70        80        90       100       110    

              60        70        80        90       100       110 
pF1KB7 -SKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQF
        .: ..:  ::::::::: . ::::.::  :: ::::::.:.  .:. ::.::: :::.:
NP_775 KDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKF
          120       130       140       150       160       170    

             120       130       140       150       160       170 
pF1KB7 PQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPR
       : ::::::::::.::::::::..:::: ::  .:: :: .  : .  :. .  :  ::  
NP_775 PLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLS
          180       190       200       210       220       230    

             180       190       200       210                     
pF1KB7 SKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILGSS---------------
       :: ::::::::... :   . . ..::.:.::::.:::: :: ..               
NP_775 SKTGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHF
          240       250       260       270       280       290    

                       220       230       240       250       260 
pF1KB7 ---------------TVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLD
                      ....:  ::::::::... ::.:...: .:.::   ::.:::. .
NP_775 WQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWE
          300       310       320       330       340       350    

             270       280       290       300       310       320 
pF1KB7 EWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWR
       .:.  .:..::: : . :. . ::: . :.::::. :: : .: .. .  .. .:. : .
NP_775 QWVVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIE
          360       370       380       390       400       410    

             330       340            350       360       370      
pF1KB7 NVDLNSITKQTLYTMEDSRDEHRKLITQ-----LYQEFDHLLEEQSPIESYIEWLDTMVD
        :::::: .:.: :.  : : .  . :.     ..::.  ::.... .:..::::::.:.
NP_775 RVDLNSIGSQALLTISGSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVE
          420       430       440       450       460       470    

        380       390       400       410       420       430      
pF1KB7 RCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLY
       . :.:.. .   :::: ::.::: :: ::.::....::..: ::::::::....:.:.: 
NP_775 QRVIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILL
          480       490       500       510       520       530    

        440       450            460       470       480       490 
pF1KB7 LLESLHCQERANELM----RAMKG-EGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATS
        .:.   ... .::.    . ::. ..: :           :  . . . : . .:. . 
NP_775 AMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESH
          540       550       560       570       580       590    

                      500         510       520          530       
pF1KB7 VE---VPPPSS------PVSN--PSPEYTGLSTTGAMQSYTWS---LTYTVTTAAGSPAE
       ::   .: :::      :. .  :. .  ..  :: :.    .   .:  .. : .: . 
NP_775 VETTYLPLPSSQPGGLGPALHQFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGS
          600       610       620       630       640       650    

       540        550             560          570       580       
pF1KB7 NSQQLPCM-RNTHV------PSSSVTHRIPVYPH--REEHG-YTGSYNYGSYGNQHPHPM
         .: :   :   :      ::   :.  :.::   . .:  :. : :: .    .::  
NP_775 VINQGPMAGRPPSVGPVLSAPSHCSTYPEPIYPTLPQANHDFYSTSSNYQTVFRAQPHST
          660       670       680       690       700       710    

       590        600          610       620        630       640  
pF1KB7 QSQYPA-LPHDTAIS---GPLHYAPYHRSSAQYPFNS-PTSRMEPCLMSSTPRLHPTPVT
       .. ::    :   ..     :    .  : :  :.:: : : . : :..           
NP_775 SGLYPHHTEHGRCMAWTEQQLSRDFFSGSCAGSPYNSRPPSSYGPSLQAQDSHNMQFLNT
          720       730       740       750       760       770    

            650       660       670       680       690       700  
pF1KB7 PRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTG
                                                                   
NP_775 GSFNFLSNTGAASCQGATLPPNSPNGYYGSNINYPESHRLGSMVNQHVSVISSIRSLPPY
          780       790       800       810       820       830    

>>XP_016865966 (OMIM: 612659,615710) PREDICTED: DNA-bind  (802 aa)
 initn: 951 init1: 573 opt: 582  Z-score: 409.0  bits: 86.4 E(85289): 4.8e-16
Smith-Waterman score: 1220; 37.6% identity (61.2% similar) in 636 aa overlap (65-631:2-637)

           40        50        60        70        80        90    
pF1KB7 SLGNVSNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKND
                                     ::::: . ::::.::  :: ::::::.:. 
XP_016                              MLEENYIVCEGVCLPRCILYAHYLDFCRKEK
                                            10        20        30 

          100       110       120       130       140       150    
pF1KB7 TQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVS
        .:. ::.::: :::.:: ::::::::::.::::::::..:::: ::  .:: :: .  :
XP_016 LEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFS
              40        50        60        70        80        90 

          160       170       180       190       200       210    
pF1KB7 ETGKKEVSKQTVAYSPRSKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILG
        .  :. .  :  ::  :: ::::::::... :   . . ..::.:.::::.:::: :: 
XP_016 GSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILD
             100       110       120       130       140       150 

                                        220       230       240    
pF1KB7 SS------------------------------TVVNIVGVCDSILYKAISGVLMPTVLQA
       ..                              ....:  ::::::::... ::.:...: 
XP_016 NAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQE
             160       170       180       190       200       210 

          250       260       270       280       290       300    
pF1KB7 LPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASR
       .:.::   ::.:::. ..:.  .:..::: : . :. . ::: . :.::::. :: : .:
XP_016 MPESLLADIRNFAKNWEQWVVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIAR
             220       230       240       250       260       270 

          310       320       330       340            350         
pF1KB7 TVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQ-----LYQEFDHLLE
        .. .  .. .:. : . :::::: .:.: :.  : : .  . :.     ..::.  ::.
XP_016 PALFDQHVVNSMVSDIERVDLNSIGSQALLTISGSTDTESGIYTEHDSITVFQELKDLLK
             280       290       300       310       320       330 

     360       370       380       390       400       410         
pF1KB7 EQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPS
       ... .:..::::::.:.. :.:.. .   :::: ::.::: :: ::.::....::..: :
XP_016 KNATVEAFIEWLDTVVEQRVIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASS
             340       350       360       370       380       390 

     420       430       440       450            460       470    
pF1KB7 FGSFHLIHLMFDDYVLYLLESLHCQERANELM----RAMKG-EGSTAEVREEIILTEAAA
       :::::::....:.:.:  .:.   ... .::.    . ::. ..: :           : 
XP_016 FGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLAN
             400       410       420       430       440       450 

          480       490                500         510       520   
pF1KB7 PTPSPVPSFSPAKSATSVE---VPPPSS------PVSN--PSPEYTGLSTTGAMQSYTWS
        . . . : . .:. . ::   .: :::      :. .  :. .  ..  :: :.    .
XP_016 RNKGSMVSSDAVKNESHVETTYLPLPSSQPGGLGPALHQFPAGNTDNMPLTGQMELSQIA
             460       470       480       490       500       510 

              530       540        550             560          570
pF1KB7 ---LTYTVTTAAGSPAENSQQLPCM-RNTHV------PSSSVTHRIPVYPH--REEHG-Y
          .:  .. : .: .   .: :   :   :      ::   :.  :.::   . .:  :
XP_016 GHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCSTYPEPIYPTLPQANHDFY
             520       530       540       550       560       570 

              580       590        600          610       620      
pF1KB7 TGSYNYGSYGNQHPHPMQSQYPA-LPHDTAIS---GPLHYAPYHRSSAQYPFNS-PTSRM
       . : :: .    .::  .. ::    :   ..     :    .  : :  :.:: : : .
XP_016 STSSNYQTVFRAQPHSTSGLYPHHTEHGRCMAWTEQQLSRDFFSGSCAGSPYNSRPPSSY
             580       590       600       610       620       630 

         630       640       650       660       670       680     
pF1KB7 EPCLMSSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEH
        : :..                                                      
XP_016 GPSLQAQDSHNMQFLNTGSFNFLSNTGAASCQGATLPPNSPNGYYGSNINYPESHRLGSM
             640       650       660       670       680       690 

>>XP_006716910 (OMIM: 601337) PREDICTED: transcription f  (492 aa)
 initn: 596 init1: 299 opt: 549  Z-score: 389.7  bits: 82.1 E(85289): 5.7e-15
Smith-Waterman score: 568; 35.0% identity (66.7% similar) in 303 aa overlap (168-469:108-390)

       140       150       160       170        180       190      
pF1KB7 SQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKL-GTLLPEFPNVKDLNLPASLPEE
                                     ::: .   :: . :  :.....  . ::. 
XP_006 LYREHCEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIE--SRLPKA
        80        90       100       110       120         130     

        200       210       220       230       240       250      
pF1KB7 KVSTFIMMYRTHCQRILGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKF
       :. :.       :..     .... .  ::  .:.:.  .:.: ::. .:..:::.::.:
XP_006 KLITL-------CKH----ESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNF
         140                  150       160       170       180    

        260       270       280       290       300       310      
pF1KB7 AKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQM
       ::.:. ::. :....:. . . :      :.: ::: :::::: ::.:.:.....   ::
XP_006 AKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQM
          190       200       210       220       230       240    

        320       330       340       350       360       370      
pF1KB7 LEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVD
       : :   ::. .. .:. .. .   :..  .. .:  .:   :..:: .:..  :::... 
XP_006 LSDLNRVDFANVQEQASWVCQC--DDN--MVQRLETDFKMTLQQQSTLEQWAAWLDNVMM
          250       260           270       280       290       300

        380       390       400       410       420       430      
pF1KB7 RCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLY
       . ..:    :  :. :.:.:::: :: ... ::::.::.:: ::::::::.:..:.:..:
XP_006 Q-ALKPYEGRP-SFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFY
               310        320       330       340       350        

        440       450       460       470       480       490      
pF1KB7 LLESLHCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPP
       :.:    :  ..:   :. :: . .. ..  :.                           
XP_006 LVEHRVAQA-TGETPIAVMGETNLVDEKNTPIMELFISKLLNFGDLNAVSPGNLDKDEGS
      360        370       380       390       400       410       

        500       510       520       530       540       550      
pF1KB7 PSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVT
                                                                   
XP_006 EVESEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQ
       420       430       440       450       460       470       

>>XP_016870491 (OMIM: 601337) PREDICTED: transcription f  (501 aa)
 initn: 596 init1: 299 opt: 549  Z-score: 389.6  bits: 82.1 E(85289): 5.8e-15
Smith-Waterman score: 568; 35.0% identity (66.7% similar) in 303 aa overlap (168-469:117-399)

       140       150       160       170        180       190      
pF1KB7 SQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKL-GTLLPEFPNVKDLNLPASLPEE
                                     ::: .   :: . :  :.....  . ::. 
XP_016 LYREHCEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIE--SRLPKA
         90       100       110       120       130         140    

        200       210       220       230       240       250      
pF1KB7 KVSTFIMMYRTHCQRILGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKF
       :. :.       :..     .... .  ::  .:.:.  .:.: ::. .:..:::.::.:
XP_016 KLITL-------CKH----ESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNF
                 150           160       170       180       190   

        260       270       280       290       300       310      
pF1KB7 AKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQM
       ::.:. ::. :....:. . . :      :.: ::: :::::: ::.:.:.....   ::
XP_016 AKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQM
           200       210       220       230       240       250   

        320       330       340       350       360       370      
pF1KB7 LEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVD
       : :   ::. .. .:. .. .   :..  .. .:  .:   :..:: .:..  :::... 
XP_016 LSDLNRVDFANVQEQASWVCQC--DDN--MVQRLETDFKMTLQQQSTLEQWAAWLDNVMM
           260       270           280       290       300         

        380       390       400       410       420       430      
pF1KB7 RCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLY
       . ..:    :  :. :.:.:::: :: ... ::::.::.:: ::::::::.:..:.:..:
XP_016 Q-ALKPYEGRP-SFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFY
     310         320       330       340       350       360       

        440       450       460       470       480       490      
pF1KB7 LLESLHCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPP
       :.:    :  ..:   :. :: . .. ..  :.                           
XP_016 LVEHRVAQA-TGETPIAVMGETNLVDEKNTPIMELFISKLLNFGDLNAVSPGNLDKDEGS
       370        380       390       400       410       420      

        500       510       520       530       540       550      
pF1KB7 PSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVT
                                                                   
XP_016 EVESEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQ
        430       440       450       460       470       480      

>>XP_016870490 (OMIM: 601337) PREDICTED: transcription f  (724 aa)
 initn: 963 init1: 364 opt: 376  Z-score: 269.9  bits: 60.5 E(85289): 2.7e-08
Smith-Waterman score: 841; 35.4% identity (58.8% similar) in 497 aa overlap (48-457:142-631)

        20        30        40        50           60        70    
pF1KB7 IERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHST---PATLQWLEENYEIAEG
                                     ::.  :  :.:   ::::::: .::: :::
XP_016 MVGTGGIQMGVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATLQWLLDNYETAEG
             120       130       140       150       160       170 

           80        90       100       110       120       130    
pF1KB7 VCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAV
       : .:::.:: :::  :...  .:::::::::.::. :  : ::::::::.:::::::: :
XP_016 VSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRRLGTRGNSKYHYYGIRV
             180       190       200       210       220       230 

                                140       150        160           
pF1KB7 KESS----------------------QYYDVMYSKKGAA-WVSETGKKE---VSKQTVAY
       : .:                      : :  : .  :.:   . .:..    : . ..: 
XP_016 KPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTGSGQQTGTSVEQTVIAQ
             240       250       260       270       280       290 

      170           180       190       200       210              
pF1KB7 SPRSKL----GTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRIL-----------
       : . .     .  :::: .:.  .:: .   : ....  .:: ::. ::           
XP_016 SQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREHCEAILDVVVNLQFSLI
             300       310       320       330       340       350 

                                                      220       230
pF1KB7 -----------------GSS--------------------------TVVNIVGVCDSILY
                        :..                          .... .  ::  .:
XP_016 EKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCKHESILKWMCNCDHGMY
             360       370       380       390       400       410 

              240       250       260       270       280       290
pF1KB7 KAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQIL
       .:.  .:.: ::. .:..:::.::.:::.:. ::. :....:. . . :      :.: :
XP_016 QALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTL
             420       430       440       450       460       470 

              300       310       320       330       340       350
pF1KB7 RRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQL
       :: :::::: ::.:.:.....   ::: :   ::. .. .:. .. .   :..  .. .:
XP_016 RRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQ--CDDN--MVQRL
             480       490       500       510         520         

              360       370       380       390       400       410
pF1KB7 YQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIR
         .:   :..:: .:..  :::... . ..:    :  :. :.:.:::: :: ... :::
XP_016 ETDFKMTLQQQSTLEQWAAWLDNVMMQ-ALKPYEGRP-SFPKAARQFLLKWSFYSSMVIR
       530       540       550        560        570       580     

              420       430       440       450       460       470
pF1KB7 DMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEVREEIILT
       :.::.:: ::::::::.:..:.:..::.:  .  . ..:   :. ::             
XP_016 DLTLRSAASFGSFHLIRLLYDEYMFYLVEH-RVAQATGETPIAVMGEFGDLNAVSPGNLD
         590       600       610        620       630       640    

              480       490       500       510       520       530
pF1KB7 EAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTT
                                                                   
XP_016 KDEGSEVESEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPSLLNPIHSEHI
          650       660       670       680       690       700    

>>XP_011516302 (OMIM: 601337) PREDICTED: transcription f  (745 aa)
 initn: 949 init1: 367 opt: 376  Z-score: 269.7  bits: 60.5 E(85289): 2.8e-08
Smith-Waterman score: 845; 34.8% identity (58.7% similar) in 509 aa overlap (48-469:142-643)

        20        30        40        50           60        70    
pF1KB7 IERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHST---PATLQWLEENYEIAEG
                                     ::.  :  :.:   ::::::: .::: :::
XP_011 MVGTGGIQMGVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATLQWLLDNYETAEG
             120       130       140       150       160       170 

           80        90       100       110       120       130    
pF1KB7 VCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAV
       : .:::.:: :::  :...  .:::::::::.::. :  : ::::::::.:::::::: :
XP_011 VSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRRLGTRGNSKYHYYGIRV
             180       190       200       210       220       230 

                                140       150        160           
pF1KB7 KESS----------------------QYYDVMYSKKGAA-WVSETGKKE---VSKQTVAY
       : .:                      : :  : .  :.:   . .:..    : . ..: 
XP_011 KPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTGSGQQTGTSVEQTVIAQ
             240       250       260       270       280       290 

      170           180       190       200       210              
pF1KB7 SPRSKL----GTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRIL-----------
       : . .     .  :::: .:.  .:: .   : ....  .:: ::. ::           
XP_011 SQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREHCEAILDVVVNLQFSLI
             300       310       320       330       340       350 

                                                      220       230
pF1KB7 -----------------GSS--------------------------TVVNIVGVCDSILY
                        :..                          .... .  ::  .:
XP_011 EKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCKHESILKWMCNCDHGMY
             360       370       380       390       400       410 

              240       250       260       270       280       290
pF1KB7 KAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQIL
       .:.  .:.: ::. .:..:::.::.:::.:. ::. :....:. . . :      :.: :
XP_011 QALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTL
             420       430       440       450       460       470 

              300       310       320       330       340       350
pF1KB7 RRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQL
       :: :::::: ::.:.:.....   ::: :   ::. .. .:. .. .   :..  .. .:
XP_011 RRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQ--CDDN--MVQRL
             480       490       500       510         520         

              360       370       380       390       400       410
pF1KB7 YQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIR
         .:   :..:: .:..  :::... . ..:    :  :. :.:.:::: :: ... :::
XP_011 ETDFKMTLQQQSTLEQWAAWLDNVMMQ-ALKPYEGRP-SFPKAARQFLLKWSFYSSMVIR
       530       540       550        560        570       580     

              420       430       440       450       460       470
pF1KB7 DMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEVREEIILT
       :.::.:: ::::::::.:..:.:..::.:  .  . ..:   :. :: . .. ..  :. 
XP_011 DLTLRSAASFGSFHLIRLLYDEYMFYLVEH-RVAQATGETPIAVMGETNLVDEKNTPIME
         590       600       610        620       630       640    

              480       490       500       510       520       530
pF1KB7 EAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTT
                                                                   
XP_011 LFISKLLNFGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTELSQAFPVGCM
          650       660       670       680       690       700    




705 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 06:34:06 2016 done: Fri Nov  4 06:34:08 2016
 Total Scan time: 12.040 Total Display time:  0.190

Function used was FASTA [36.3.4 Apr, 2011]
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