FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7282, 705 aa 1>>>pF1KB7282 705 - 705 aa - 705 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.3703+/-0.000409; mu= 1.5671+/- 0.026 mean_var=217.2560+/-44.750, 0's: 0 Z-trim(118.6): 56 B-trim: 548 in 2/58 Lambda= 0.087014 statistics sampled from 31687 (31746) to 31687 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.372), width: 16 Scan time: 12.040 The best scores are: opt bits E(85289) NP_115880 (OMIM: 603958) transcription factor RFX4 ( 641) 3348 433.5 1.2e-120 NP_998759 (OMIM: 603958) transcription factor RFX4 ( 735) 3348 433.6 1.3e-120 NP_001193620 (OMIM: 603958) transcription factor R ( 744) 3348 433.6 1.4e-120 XP_011533891 (OMIM: 612659,615710) PREDICTED: DNA- ( 892) 1114 153.2 4.2e-36 NP_775831 (OMIM: 612659,615710) DNA-binding protei ( 928) 623 91.6 1.5e-17 XP_016865966 (OMIM: 612659,615710) PREDICTED: DNA- ( 802) 582 86.4 4.8e-16 XP_006716910 (OMIM: 601337) PREDICTED: transcripti ( 492) 549 82.1 5.7e-15 XP_016870491 (OMIM: 601337) PREDICTED: transcripti ( 501) 549 82.1 5.8e-15 XP_016870490 (OMIM: 601337) PREDICTED: transcripti ( 724) 376 60.5 2.7e-08 XP_011516302 (OMIM: 601337) PREDICTED: transcripti ( 745) 376 60.5 2.8e-08 XP_016882597 (OMIM: 142765) PREDICTED: DNA-binding ( 653) 374 60.2 3e-08 NP_602309 (OMIM: 142765) DNA-binding protein RFX2 ( 698) 374 60.2 3.1e-08 NP_002909 (OMIM: 600006) MHC class II regulatory f ( 979) 370 59.8 5.8e-08 XP_011526472 (OMIM: 600006) PREDICTED: MHC class I ( 980) 370 59.8 5.8e-08 XP_011526471 (OMIM: 600006) PREDICTED: MHC class I ( 980) 370 59.8 5.8e-08 XP_011526469 (OMIM: 600006) PREDICTED: MHC class I (1089) 370 59.8 6.4e-08 XP_011526468 (OMIM: 600006) PREDICTED: MHC class I (1089) 370 59.8 6.4e-08 XP_011526467 (OMIM: 600006) PREDICTED: MHC class I (1089) 370 59.8 6.4e-08 NP_001269046 (OMIM: 601337) transcription factor R ( 413) 347 56.7 2.1e-07 XP_016882596 (OMIM: 142765) PREDICTED: DNA-binding ( 678) 348 56.9 2.9e-07 XP_011526474 (OMIM: 142765) PREDICTED: DNA-binding ( 687) 348 56.9 3e-07 XP_011526473 (OMIM: 142765) PREDICTED: DNA-binding ( 723) 348 57.0 3.1e-07 NP_000626 (OMIM: 142765) DNA-binding protein RFX2 ( 723) 348 57.0 3.1e-07 XP_011516303 (OMIM: 601337) PREDICTED: transcripti ( 687) 347 56.8 3.2e-07 NP_002910 (OMIM: 601337) transcription factor RFX3 ( 707) 347 56.8 3.3e-07 XP_011526470 (OMIM: 600006) PREDICTED: MHC class I ( 991) 350 57.3 3.4e-07 NP_001269045 (OMIM: 601337) transcription factor R ( 749) 347 56.8 3.5e-07 NP_602304 (OMIM: 601337) transcription factor RFX3 ( 749) 347 56.8 3.5e-07 XP_016870489 (OMIM: 601337) PREDICTED: transcripti ( 770) 347 56.9 3.6e-07 XP_006716908 (OMIM: 601337) PREDICTED: transcripti ( 770) 347 56.9 3.6e-07 XP_006716907 (OMIM: 601337) PREDICTED: transcripti ( 770) 347 56.9 3.6e-07 XP_011516300 (OMIM: 601337) PREDICTED: transcripti ( 770) 347 56.9 3.6e-07 XP_011516301 (OMIM: 601337) PREDICTED: transcripti ( 770) 347 56.9 3.6e-07 XP_006716906 (OMIM: 601337) PREDICTED: transcripti ( 770) 347 56.9 3.6e-07 XP_006716903 (OMIM: 601337) PREDICTED: transcripti ( 780) 347 56.9 3.6e-07 >>NP_115880 (OMIM: 603958) transcription factor RFX4 iso (641 aa) initn: 3339 init1: 3339 opt: 3348 Z-score: 2287.0 bits: 433.5 E(85289): 1.2e-120 Smith-Waterman score: 3839; 91.4% identity (93.3% similar) in 641 aa overlap (98-705:1-641) 70 80 90 100 110 120 pF1KB7 NYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFG--KIIRQQFPQLTTRRLGTRGQS .: :.:: ... . :. .: .:. . NP_115 MNWAAFGGSEFFIPEGIQIDSRCPLSRNIT 10 20 30 130 140 150 160 170 180 pF1KB7 K-YHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPEFPNV . :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 EWYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPEFPNV 40 50 60 70 80 90 190 200 210 pF1KB7 KDLNLPASLPEEKVSTFIMMYRTHCQRIL------------------------------G ::::::::::::::::::::::::::::: : NP_115 KDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB7 SSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 SSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPEN 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB7 LRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 LRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLY 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB7 TMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 TMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVA 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB7 QQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 QQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAM 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB7 KGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 KGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTT 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB7 GAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGYTGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 GAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGYTGSY 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB7 NYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLMSSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 NYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLMSSTP 520 530 540 550 560 570 640 650 660 670 680 690 pF1KB7 RLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFPGFAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 RLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFPGFAY 580 590 600 610 620 630 700 pF1KB7 INGEASTGWAK ::::::::::: NP_115 INGEASTGWAK 640 >>NP_998759 (OMIM: 603958) transcription factor RFX4 iso (735 aa) initn: 3339 init1: 3339 opt: 3348 Z-score: 2286.1 bits: 433.6 E(85289): 1.3e-120 Smith-Waterman score: 4694; 95.9% identity (95.9% similar) in 735 aa overlap (1-705:1-735) 10 20 30 40 50 60 pF1KB7 MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 TLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 TRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPE 130 140 150 160 170 180 190 200 210 pF1KB7 FPNVKDLNLPASLPEEKVSTFIMMYRTHCQRIL--------------------------- ::::::::::::::::::::::::::::::::: NP_998 FPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHML 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 ---GSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 PVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHD 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 LPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 LPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITK 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB7 QTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 QTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSL 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB7 KKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 KKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANEL 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB7 MRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 MRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTG 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB7 LSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 LSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGY 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB7 TGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 TGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLM 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB7 SSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 SSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFP 670 680 690 700 710 720 700 pF1KB7 GFAYINGEASTGWAK ::::::::::::::: NP_998 GFAYINGEASTGWAK 730 >>NP_001193620 (OMIM: 603958) transcription factor RFX4 (744 aa) initn: 3339 init1: 3339 opt: 3348 Z-score: 2286.0 bits: 433.6 E(85289): 1.4e-120 Smith-Waterman score: 4601; 95.9% identity (95.9% similar) in 723 aa overlap (13-705:22-744) 10 20 30 40 50 pF1KB7 MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNR ::::::::::::::::::::::::::::::::::::::: NP_001 MIKRRAHPGAGGDRTRPRRRRSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 ASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 PQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPR 130 140 150 160 170 180 180 190 200 210 pF1KB7 SKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRIL------------------ :::::::::::::::::::::::::::::::::::::::::: NP_001 SKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHF 190 200 210 220 230 240 220 230 240 250 260 pF1KB7 ------------GSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLD :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLD 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB7 EWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWR 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB7 NVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVK 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB7 VAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESL 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB7 HCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPV 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB7 SNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPV 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB7 YPHREEHGYTGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YPHREEHGYTGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSP 610 620 630 640 650 660 630 640 650 660 670 680 pF1KB7 TSRMEPCLMSSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSRMEPCLMSSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNS 670 680 690 700 710 720 690 700 pF1KB7 EYEHMQHFPGFAYINGEASTGWAK :::::::::::::::::::::::: NP_001 EYEHMQHFPGFAYINGEASTGWAK 730 740 >>XP_011533891 (OMIM: 612659,615710) PREDICTED: DNA-bind (892 aa) initn: 1167 init1: 452 opt: 1114 Z-score: 769.2 bits: 153.2 E(85289): 4.2e-36 Smith-Waterman score: 1150; 35.6% identity (61.5% similar) in 654 aa overlap (25-631:85-727) 10 20 30 40 50 pF1KB7 MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRA-- ::.. ..: : ..... .:.. XP_011 GEQGGGEKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAADQYLSQKKTITQIV 60 70 80 90 100 110 60 70 80 90 100 110 pF1KB7 -SKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQF .: ..: ::::::::: . ::::.:: :: ::::::.:. .:. ::.::: :::.: XP_011 KDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKF 120 130 140 150 160 170 120 130 140 150 160 170 pF1KB7 PQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETG-KKEVSKQTVAYSP : ::::::::::.::::::::..:::: :: .:: :: . : . :.::. . : XP_011 PLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEVDTLIMMY-- 180 190 200 210 220 230 180 190 200 210 220 pF1KB7 RSKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRT----HCQRILGSSTVVNIVGVCD ... .: :. . :. :... :.. . : .: . ....: ::: XP_011 KTHCQCILD---NAINGNF------EEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCD 240 250 260 270 280 230 240 250 260 270 280 pF1KB7 SILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRF :::::... ::.:...: .:.:: ::.:::. ..:. .:..::: : . :. . ::: XP_011 SILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTDKKIPIVRRF 290 300 310 320 330 340 290 300 310 320 330 340 pF1KB7 SQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRKL . :.::::. :: : .: .. . .. .:. : . :::::: .:.: :. : : . . XP_011 VSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERVDLNSIGSQALLTISGSTDTESGI 350 360 370 380 390 400 350 360 370 380 390 400 pF1KB7 ITQ-----LYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMW :. ..::. ::.... .:..::::::.:.. :.:.. . :::: ::.::: : XP_011 YTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGRSLKKRAQDFLLKW 410 420 430 440 450 460 410 420 430 440 450 pF1KB7 SCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELM----RAMKG- : ::.::....::..: ::::::::....:.:.: .:. ... .::. . ::. XP_011 SFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNS 470 480 490 500 510 520 460 470 480 490 500 pF1KB7 EGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVE---VPPPSS------PVSN--PS ..: : : . . . : . .:. . :: .: ::: :. . :. XP_011 DASKAAFTASPSSCFLANRNKGSMVSSDAVKNESHVETTYLPLPSSQPGGLGPALHQFPA 530 540 550 560 570 580 510 520 530 540 550 pF1KB7 PEYTGLSTTGAMQSYTWS---LTYTVTTAAGSPAENSQQLPCM-RNTHV------PSSSV . .. :: :. . .: .. : .: . .: : : : :: XP_011 GNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCS 590 600 610 620 630 640 560 570 580 590 600 pF1KB7 THRIPVYPH--REEHG-YTGSYNYGSYGNQHPHPMQSQYPA-LPHDTAIS---GPLHYAP :. :.:: . .: :. : :: . .:: .. :: : .. : XP_011 TYPEPIYPTLPQANHDFYSTSSNYQTVFRAQPHSTSGLYPHHTEHGRCMAWTEQQLSRDF 650 660 670 680 690 700 610 620 630 640 650 660 pF1KB7 YHRSSAQYPFNS-PTSRMEPCLMSSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGN . : : :.:: : : . : :.. XP_011 FSGSCAGSPYNSRPPSSYGPSLQAQDSHNMQFLNTGSFNFLSNTGAASCQGATLPPNSPN 710 720 730 740 750 760 >>NP_775831 (OMIM: 612659,615710) DNA-binding protein RF (928 aa) initn: 983 init1: 605 opt: 623 Z-score: 435.9 bits: 91.6 E(85289): 1.5e-17 Smith-Waterman score: 1261; 36.8% identity (61.1% similar) in 679 aa overlap (25-631:85-763) 10 20 30 40 50 pF1KB7 MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRA-- ::.. ..: : ..... .:.. NP_775 GEQGGGEKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAADQYLSQKKTITQIV 60 70 80 90 100 110 60 70 80 90 100 110 pF1KB7 -SKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQF .: ..: ::::::::: . ::::.:: :: ::::::.:. .:. ::.::: :::.: NP_775 KDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKF 120 130 140 150 160 170 120 130 140 150 160 170 pF1KB7 PQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPR : ::::::::::.::::::::..:::: :: .:: :: . : . :. . : :: NP_775 PLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLS 180 190 200 210 220 230 180 190 200 210 pF1KB7 SKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILGSS--------------- :: ::::::::... : . . ..::.:.::::.:::: :: .. NP_775 SKTGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHF 240 250 260 270 280 290 220 230 240 250 260 pF1KB7 ---------------TVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLD ....: ::::::::... ::.:...: .:.:: ::.:::. . NP_775 WQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWE 300 310 320 330 340 350 270 280 290 300 310 320 pF1KB7 EWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWR .:. .:..::: : . :. . ::: . :.::::. :: : .: .. . .. .:. : . NP_775 QWVVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIE 360 370 380 390 400 410 330 340 350 360 370 pF1KB7 NVDLNSITKQTLYTMEDSRDEHRKLITQ-----LYQEFDHLLEEQSPIESYIEWLDTMVD :::::: .:.: :. : : . . :. ..::. ::.... .:..::::::.:. NP_775 RVDLNSIGSQALLTISGSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVE 420 430 440 450 460 470 380 390 400 410 420 430 pF1KB7 RCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLY . :.:.. . :::: ::.::: :: ::.::....::..: ::::::::....:.:.: NP_775 QRVIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILL 480 490 500 510 520 530 440 450 460 470 480 490 pF1KB7 LLESLHCQERANELM----RAMKG-EGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATS .:. ... .::. . ::. ..: : : . . . : . .:. . NP_775 AMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESH 540 550 560 570 580 590 500 510 520 530 pF1KB7 VE---VPPPSS------PVSN--PSPEYTGLSTTGAMQSYTWS---LTYTVTTAAGSPAE :: .: ::: :. . :. . .. :: :. . .: .. : .: . NP_775 VETTYLPLPSSQPGGLGPALHQFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGS 600 610 620 630 640 650 540 550 560 570 580 pF1KB7 NSQQLPCM-RNTHV------PSSSVTHRIPVYPH--REEHG-YTGSYNYGSYGNQHPHPM .: : : : :: :. :.:: . .: :. : :: . .:: NP_775 VINQGPMAGRPPSVGPVLSAPSHCSTYPEPIYPTLPQANHDFYSTSSNYQTVFRAQPHST 660 670 680 690 700 710 590 600 610 620 630 640 pF1KB7 QSQYPA-LPHDTAIS---GPLHYAPYHRSSAQYPFNS-PTSRMEPCLMSSTPRLHPTPVT .. :: : .. : . : : :.:: : : . : :.. NP_775 SGLYPHHTEHGRCMAWTEQQLSRDFFSGSCAGSPYNSRPPSSYGPSLQAQDSHNMQFLNT 720 730 740 750 760 770 650 660 670 680 690 700 pF1KB7 PRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTG NP_775 GSFNFLSNTGAASCQGATLPPNSPNGYYGSNINYPESHRLGSMVNQHVSVISSIRSLPPY 780 790 800 810 820 830 >>XP_016865966 (OMIM: 612659,615710) PREDICTED: DNA-bind (802 aa) initn: 951 init1: 573 opt: 582 Z-score: 409.0 bits: 86.4 E(85289): 4.8e-16 Smith-Waterman score: 1220; 37.6% identity (61.2% similar) in 636 aa overlap (65-631:2-637) 40 50 60 70 80 90 pF1KB7 SLGNVSNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKND ::::: . ::::.:: :: ::::::.:. XP_016 MLEENYIVCEGVCLPRCILYAHYLDFCRKEK 10 20 30 100 110 120 130 140 150 pF1KB7 TQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVS .:. ::.::: :::.:: ::::::::::.::::::::..:::: :: .:: :: . : XP_016 LEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB7 ETGKKEVSKQTVAYSPRSKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILG . :. . : :: :: ::::::::... : . . ..::.:.::::.:::: :: XP_016 GSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILD 100 110 120 130 140 150 220 230 240 pF1KB7 SS------------------------------TVVNIVGVCDSILYKAISGVLMPTVLQA .. ....: ::::::::... ::.:...: XP_016 NAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB7 LPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASR .:.:: ::.:::. ..:. .:..::: : . :. . ::: . :.::::. :: : .: XP_016 MPESLLADIRNFAKNWEQWVVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIAR 220 230 240 250 260 270 310 320 330 340 350 pF1KB7 TVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQ-----LYQEFDHLLE .. . .. .:. : . :::::: .:.: :. : : . . :. ..::. ::. XP_016 PALFDQHVVNSMVSDIERVDLNSIGSQALLTISGSTDTESGIYTEHDSITVFQELKDLLK 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB7 EQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPS ... .:..::::::.:.. :.:.. . :::: ::.::: :: ::.::....::..: : XP_016 KNATVEAFIEWLDTVVEQRVIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASS 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB7 FGSFHLIHLMFDDYVLYLLESLHCQERANELM----RAMKG-EGSTAEVREEIILTEAAA :::::::....:.:.: .:. ... .::. . ::. ..: : : XP_016 FGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLAN 400 410 420 430 440 450 480 490 500 510 520 pF1KB7 PTPSPVPSFSPAKSATSVE---VPPPSS------PVSN--PSPEYTGLSTTGAMQSYTWS . . . : . .:. . :: .: ::: :. . :. . .. :: :. . XP_016 RNKGSMVSSDAVKNESHVETTYLPLPSSQPGGLGPALHQFPAGNTDNMPLTGQMELSQIA 460 470 480 490 500 510 530 540 550 560 570 pF1KB7 ---LTYTVTTAAGSPAENSQQLPCM-RNTHV------PSSSVTHRIPVYPH--REEHG-Y .: .. : .: . .: : : : :: :. :.:: . .: : XP_016 GHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCSTYPEPIYPTLPQANHDFY 520 530 540 550 560 570 580 590 600 610 620 pF1KB7 TGSYNYGSYGNQHPHPMQSQYPA-LPHDTAIS---GPLHYAPYHRSSAQYPFNS-PTSRM . : :: . .:: .. :: : .. : . : : :.:: : : . XP_016 STSSNYQTVFRAQPHSTSGLYPHHTEHGRCMAWTEQQLSRDFFSGSCAGSPYNSRPPSSY 580 590 600 610 620 630 630 640 650 660 670 680 pF1KB7 EPCLMSSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEH : :.. XP_016 GPSLQAQDSHNMQFLNTGSFNFLSNTGAASCQGATLPPNSPNGYYGSNINYPESHRLGSM 640 650 660 670 680 690 >>XP_006716910 (OMIM: 601337) PREDICTED: transcription f (492 aa) initn: 596 init1: 299 opt: 549 Z-score: 389.7 bits: 82.1 E(85289): 5.7e-15 Smith-Waterman score: 568; 35.0% identity (66.7% similar) in 303 aa overlap (168-469:108-390) 140 150 160 170 180 190 pF1KB7 SQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKL-GTLLPEFPNVKDLNLPASLPEE ::: . :: . : :..... . ::. XP_006 LYREHCEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIE--SRLPKA 80 90 100 110 120 130 200 210 220 230 240 250 pF1KB7 KVSTFIMMYRTHCQRILGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKF :. :. :.. .... . :: .:.:. .:.: ::. .:..:::.::.: XP_006 KLITL-------CKH----ESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNF 140 150 160 170 180 260 270 280 290 300 310 pF1KB7 AKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQM ::.:. ::. :....:. . . : :.: ::: :::::: ::.:.:..... :: XP_006 AKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQM 190 200 210 220 230 240 320 330 340 350 360 370 pF1KB7 LEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVD : : ::. .. .:. .. . :.. .. .: .: :..:: .:.. :::... XP_006 LSDLNRVDFANVQEQASWVCQC--DDN--MVQRLETDFKMTLQQQSTLEQWAAWLDNVMM 250 260 270 280 290 300 380 390 400 410 420 430 pF1KB7 RCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLY . ..: : :. :.:.:::: :: ... ::::.::.:: ::::::::.:..:.:..: XP_006 Q-ALKPYEGRP-SFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFY 310 320 330 340 350 440 450 460 470 480 490 pF1KB7 LLESLHCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPP :.: : ..: :. :: . .. .. :. XP_006 LVEHRVAQA-TGETPIAVMGETNLVDEKNTPIMELFISKLLNFGDLNAVSPGNLDKDEGS 360 370 380 390 400 410 500 510 520 530 540 550 pF1KB7 PSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVT XP_006 EVESEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQ 420 430 440 450 460 470 >>XP_016870491 (OMIM: 601337) PREDICTED: transcription f (501 aa) initn: 596 init1: 299 opt: 549 Z-score: 389.6 bits: 82.1 E(85289): 5.8e-15 Smith-Waterman score: 568; 35.0% identity (66.7% similar) in 303 aa overlap (168-469:117-399) 140 150 160 170 180 190 pF1KB7 SQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKL-GTLLPEFPNVKDLNLPASLPEE ::: . :: . : :..... . ::. XP_016 LYREHCEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIE--SRLPKA 90 100 110 120 130 140 200 210 220 230 240 250 pF1KB7 KVSTFIMMYRTHCQRILGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKF :. :. :.. .... . :: .:.:. .:.: ::. .:..:::.::.: XP_016 KLITL-------CKH----ESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNF 150 160 170 180 190 260 270 280 290 300 310 pF1KB7 AKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQM ::.:. ::. :....:. . . : :.: ::: :::::: ::.:.:..... :: XP_016 AKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQM 200 210 220 230 240 250 320 330 340 350 360 370 pF1KB7 LEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVD : : ::. .. .:. .. . :.. .. .: .: :..:: .:.. :::... XP_016 LSDLNRVDFANVQEQASWVCQC--DDN--MVQRLETDFKMTLQQQSTLEQWAAWLDNVMM 260 270 280 290 300 380 390 400 410 420 430 pF1KB7 RCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLY . ..: : :. :.:.:::: :: ... ::::.::.:: ::::::::.:..:.:..: XP_016 Q-ALKPYEGRP-SFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFY 310 320 330 340 350 360 440 450 460 470 480 490 pF1KB7 LLESLHCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPP :.: : ..: :. :: . .. .. :. XP_016 LVEHRVAQA-TGETPIAVMGETNLVDEKNTPIMELFISKLLNFGDLNAVSPGNLDKDEGS 370 380 390 400 410 420 500 510 520 530 540 550 pF1KB7 PSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVT XP_016 EVESEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQ 430 440 450 460 470 480 >>XP_016870490 (OMIM: 601337) PREDICTED: transcription f (724 aa) initn: 963 init1: 364 opt: 376 Z-score: 269.9 bits: 60.5 E(85289): 2.7e-08 Smith-Waterman score: 841; 35.4% identity (58.8% similar) in 497 aa overlap (48-457:142-631) 20 30 40 50 60 70 pF1KB7 IERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHST---PATLQWLEENYEIAEG ::. : :.: ::::::: .::: ::: XP_016 MVGTGGIQMGVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATLQWLLDNYETAEG 120 130 140 150 160 170 80 90 100 110 120 130 pF1KB7 VCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAV : .:::.:: ::: :... .:::::::::.::. : : ::::::::.:::::::: : XP_016 VSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRRLGTRGNSKYHYYGIRV 180 190 200 210 220 230 140 150 160 pF1KB7 KESS----------------------QYYDVMYSKKGAA-WVSETGKKE---VSKQTVAY : .: : : : . :.: . .:.. : . ..: XP_016 KPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTGSGQQTGTSVEQTVIAQ 240 250 260 270 280 290 170 180 190 200 210 pF1KB7 SPRSKL----GTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRIL----------- : . . . :::: .:. .:: . : .... .:: ::. :: XP_016 SQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREHCEAILDVVVNLQFSLI 300 310 320 330 340 350 220 230 pF1KB7 -----------------GSS--------------------------TVVNIVGVCDSILY :.. .... . :: .: XP_016 EKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCKHESILKWMCNCDHGMY 360 370 380 390 400 410 240 250 260 270 280 290 pF1KB7 KAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQIL .:. .:.: ::. .:..:::.::.:::.:. ::. :....:. . . : :.: : XP_016 QALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTL 420 430 440 450 460 470 300 310 320 330 340 350 pF1KB7 RRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQL :: :::::: ::.:.:..... ::: : ::. .. .:. .. . :.. .. .: XP_016 RRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQ--CDDN--MVQRL 480 490 500 510 520 360 370 380 390 400 410 pF1KB7 YQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIR .: :..:: .:.. :::... . ..: : :. :.:.:::: :: ... ::: XP_016 ETDFKMTLQQQSTLEQWAAWLDNVMMQ-ALKPYEGRP-SFPKAARQFLLKWSFYSSMVIR 530 540 550 560 570 580 420 430 440 450 460 470 pF1KB7 DMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEVREEIILT :.::.:: ::::::::.:..:.:..::.: . . ..: :. :: XP_016 DLTLRSAASFGSFHLIRLLYDEYMFYLVEH-RVAQATGETPIAVMGEFGDLNAVSPGNLD 590 600 610 620 630 640 480 490 500 510 520 530 pF1KB7 EAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTT XP_016 KDEGSEVESEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPSLLNPIHSEHI 650 660 670 680 690 700 >>XP_011516302 (OMIM: 601337) PREDICTED: transcription f (745 aa) initn: 949 init1: 367 opt: 376 Z-score: 269.7 bits: 60.5 E(85289): 2.8e-08 Smith-Waterman score: 845; 34.8% identity (58.7% similar) in 509 aa overlap (48-469:142-643) 20 30 40 50 60 70 pF1KB7 IERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHST---PATLQWLEENYEIAEG ::. : :.: ::::::: .::: ::: XP_011 MVGTGGIQMGVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATLQWLLDNYETAEG 120 130 140 150 160 170 80 90 100 110 120 130 pF1KB7 VCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAV : .:::.:: ::: :... .:::::::::.::. : : ::::::::.:::::::: : XP_011 VSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRRLGTRGNSKYHYYGIRV 180 190 200 210 220 230 140 150 160 pF1KB7 KESS----------------------QYYDVMYSKKGAA-WVSETGKKE---VSKQTVAY : .: : : : . :.: . .:.. : . ..: XP_011 KPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTGSGQQTGTSVEQTVIAQ 240 250 260 270 280 290 170 180 190 200 210 pF1KB7 SPRSKL----GTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRIL----------- : . . . :::: .:. .:: . : .... .:: ::. :: XP_011 SQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREHCEAILDVVVNLQFSLI 300 310 320 330 340 350 220 230 pF1KB7 -----------------GSS--------------------------TVVNIVGVCDSILY :.. .... . :: .: XP_011 EKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCKHESILKWMCNCDHGMY 360 370 380 390 400 410 240 250 260 270 280 290 pF1KB7 KAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQIL .:. .:.: ::. .:..:::.::.:::.:. ::. :....:. . . : :.: : XP_011 QALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTL 420 430 440 450 460 470 300 310 320 330 340 350 pF1KB7 RRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQL :: :::::: ::.:.:..... ::: : ::. .. .:. .. . :.. .. .: XP_011 RRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQ--CDDN--MVQRL 480 490 500 510 520 360 370 380 390 400 410 pF1KB7 YQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIR .: :..:: .:.. :::... . ..: : :. :.:.:::: :: ... ::: XP_011 ETDFKMTLQQQSTLEQWAAWLDNVMMQ-ALKPYEGRP-SFPKAARQFLLKWSFYSSMVIR 530 540 550 560 570 580 420 430 440 450 460 470 pF1KB7 DMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEVREEIILT :.::.:: ::::::::.:..:.:..::.: . . ..: :. :: . .. .. :. XP_011 DLTLRSAASFGSFHLIRLLYDEYMFYLVEH-RVAQATGETPIAVMGETNLVDEKNTPIME 590 600 610 620 630 640 480 490 500 510 520 530 pF1KB7 EAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTT XP_011 LFISKLLNFGDLNAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTELSQAFPVGCM 650 660 670 680 690 700 705 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:34:06 2016 done: Fri Nov 4 06:34:08 2016 Total Scan time: 12.040 Total Display time: 0.190 Function used was FASTA [36.3.4 Apr, 2011]