Result of FASTA (omim) for pF1KB7297
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7297, 1226 aa
  1>>>pF1KB7297 1226 - 1226 aa - 1226 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.6598+/-0.000464; mu= -1.2426+/- 0.029
 mean_var=368.8329+/-76.209, 0's: 0 Z-trim(120.4): 279  B-trim: 645 in 1/60
 Lambda= 0.066782
 statistics sampled from 35264 (35553) to 35264 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.417), width:  16
 Scan time: 12.260

The best scores are:                                      opt bits E(85289)
NP_631894 (OMIM: 607506) A disintegrin and metallo (1226) 8832 866.4       0
NP_542453 (OMIM: 607506) A disintegrin and metallo (1223) 8794 862.7       0
XP_011537604 (OMIM: 607506) PREDICTED: A disintegr ( 914) 6724 663.1 2.3e-189
XP_011537603 (OMIM: 607506) PREDICTED: A disintegr ( 914) 6724 663.1 2.3e-189
XP_011537605 (OMIM: 607506) PREDICTED: A disintegr ( 820) 5753 569.5  3e-161
XP_011537602 (OMIM: 607506) PREDICTED: A disintegr (1056) 5752 569.6 3.9e-161
XP_011537611 (OMIM: 607506) PREDICTED: A disintegr ( 746) 5505 545.6 4.4e-154
XP_011537608 (OMIM: 607506) PREDICTED: A disintegr ( 791) 5407 536.2 3.2e-151
XP_011537610 (OMIM: 607506) PREDICTED: A disintegr ( 791) 5407 536.2 3.2e-151
XP_011537609 (OMIM: 607506) PREDICTED: A disintegr ( 791) 5407 536.2 3.2e-151
XP_011537607 (OMIM: 607506) PREDICTED: A disintegr ( 807) 5407 536.2 3.3e-151
XP_011530724 (OMIM: 605011) PREDICTED: A disintegr (1177) 4445 443.7 3.4e-123
XP_011530723 (OMIM: 605011) PREDICTED: A disintegr (1186) 4445 443.7 3.4e-123
NP_055058 (OMIM: 605011) A disintegrin and metallo (1205) 4445 443.7 3.5e-123
NP_055059 (OMIM: 225410,604539) A disintegrin and  (1211) 4192 419.3 7.6e-116
XP_016865552 (OMIM: 225410,604539) PREDICTED: A di (1046) 3920 393.0 5.3e-108
NP_067610 (OMIM: 225410,604539) A disintegrin and  ( 566) 2132 220.5 2.5e-56
XP_011537056 (OMIM: 611681) PREDICTED: A disintegr (1911) 1521 162.2 3.1e-38
NP_079279 (OMIM: 611681) A disintegrin and metallo (1910) 1517 161.8   4e-38
NP_891550 (OMIM: 605421) A disintegrin and metallo (1935) 1503 160.4   1e-37
NP_001305710 (OMIM: 605421) A disintegrin and meta (1907) 1419 152.3 2.8e-35
NP_055087 (OMIM: 605009) A disintegrin and metallo (1686) 1399 150.4 9.7e-35
XP_005254194 (OMIM: 605009) PREDICTED: A disintegr (1689) 1399 150.4 9.7e-35
NP_008919 (OMIM: 605174) A disintegrin and metallo ( 967) 1381 148.4 2.2e-34
XP_011541550 (OMIM: 607513) PREDICTED: A disintegr ( 827) 1346 144.9   2e-33
XP_011541549 (OMIM: 607513) PREDICTED: A disintegr ( 827) 1346 144.9   2e-33
XP_016864663 (OMIM: 607513) PREDICTED: A disintegr ( 886) 1346 145.0 2.1e-33
XP_011541548 (OMIM: 607513) PREDICTED: A disintegr ( 984) 1346 145.0 2.3e-33
XP_016864665 (OMIM: 607513) PREDICTED: A disintegr ( 776) 1320 142.4 1.1e-32
XP_016864664 (OMIM: 607513) PREDICTED: A disintegr ( 780) 1315 141.9 1.5e-32
XP_011541551 (OMIM: 607513) PREDICTED: A disintegr ( 780) 1315 141.9 1.5e-32
XP_011521226 (OMIM: 607512,615458) PREDICTED: A di ( 978) 1312 141.7 2.2e-32
XP_011521225 (OMIM: 607512,615458) PREDICTED: A di (1049) 1312 141.8 2.3e-32
NP_001313287 (OMIM: 607512,615458) A disintegrin a (1049) 1312 141.8 2.3e-32
NP_955387 (OMIM: 607512,615458) A disintegrin and  (1221) 1312 141.8 2.6e-32
NP_112217 (OMIM: 606184) A disintegrin and metallo (1594) 1301 140.9 6.5e-32
XP_016865394 (OMIM: 606184) PREDICTED: A disintegr (1631) 1301 140.9 6.6e-32
NP_620687 (OMIM: 607510) A disintegrin and metallo (1224) 1279 138.7 2.3e-31
NP_008969 (OMIM: 605007) A disintegrin and metallo ( 930) 1237 134.5 3.2e-30
XP_016872634 (OMIM: 605175) PREDICTED: A disintegr ( 873) 1214 132.3 1.4e-29
NP_620686 (OMIM: 607509) A disintegrin and metallo ( 950) 1211 132.0 1.8e-29
XP_016865395 (OMIM: 606184) PREDICTED: A disintegr (1467) 1198 130.9 5.9e-29
NP_005090 (OMIM: 603876) A disintegrin and metallo ( 837) 1187 129.6 8.3e-29
XP_016875468 (OMIM: 611681) PREDICTED: A disintegr (1506) 1132 124.6   5e-27
XP_011541423 (OMIM: 605008) PREDICTED: A disintegr ( 863) 1116 122.8 9.7e-27
XP_011541422 (OMIM: 605008) PREDICTED: A disintegr ( 868) 1116 122.8 9.7e-27
XP_011541421 (OMIM: 605008) PREDICTED: A disintegr ( 892) 1116 122.8 9.9e-27
XP_011541419 (OMIM: 605008) PREDICTED: A disintegr ( 966) 1116 122.9 1.1e-26
XP_011541415 (OMIM: 605008) PREDICTED: A disintegr (1117) 1116 122.9 1.2e-26
NP_922932 (OMIM: 605008) A disintegrin and metallo (1117) 1116 122.9 1.2e-26


>>NP_631894 (OMIM: 607506) A disintegrin and metalloprot  (1226 aa)
 initn: 8832 init1: 8832 opt: 8832  Z-score: 4616.8  bits: 866.4 E(85289):    0
Smith-Waterman score: 8832; 100.0% identity (100.0% similar) in 1226 aa overlap (1-1226:1-1226)

               10        20        30        40        50        60
pF1KB7 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 RQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 RQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 FTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 FTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIG
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB7 SNNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 SNNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPI
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB7 RRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 RRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB7 EARRPCLRVPCPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHCEGDRPDTVQVCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 EARRPCLRVPCPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHCEGDRPDTVQVCS
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB7 LPACGGNHQNSTVRADVWELGTPEGQWVPQSEPLHPINKISSTEPCTGDRSVFCQMEVLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 LPACGGNHQNSTVRADVWELGTPEGQWVPQSEPLHPINKISSTEPCTGDRSVFCQMEVLD
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB7 RYCSIPGYHRLCCVSCIKKASGPNPGPDPGPTSLPPFSTPGSPLPGPQDPADAAEPPGKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 RYCSIPGYHRLCCVSCIKKASGPNPGPDPGPTSLPPFSTPGSPLPGPQDPADAAEPPGKP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB7 TGSEDHQHGRATQLPGALDTSSPGTQHPFAPETPIPGASWSISPTTPGGLPWGWTQTPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 TGSEDHQHGRATQLPGALDTSSPGTQHPFAPETPIPGASWSISPTTPGGLPWGWTQTPTP
             1150      1160      1170      1180      1190      1200

             1210      1220      
pF1KB7 VPEDKGQPGEDLRHPGTSLPAASPVT
       ::::::::::::::::::::::::::
NP_631 VPEDKGQPGEDLRHPGTSLPAASPVT
             1210      1220      

>>NP_542453 (OMIM: 607506) A disintegrin and metalloprot  (1223 aa)
 initn: 6316 init1: 6316 opt: 8794  Z-score: 4597.0  bits: 862.7 E(85289):    0
Smith-Waterman score: 8794; 99.8% identity (99.8% similar) in 1226 aa overlap (1-1226:1-1223)

               10        20        30        40        50        60
pF1KB7 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 RQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
       ::::::::   :::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 RQDFGPSG---YAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
                 370       380       390       400       410       

              430       440       450       460       470       480
pF1KB7 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
       420       430       440       450       460       470       

              490       500       510       520       530       540
pF1KB7 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
       480       490       500       510       520       530       

              550       560       570       580       590       600
pF1KB7 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
       540       550       560       570       580       590       

              610       620       630       640       650       660
pF1KB7 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
       600       610       620       630       640       650       

              670       680       690       700       710       720
pF1KB7 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
       660       670       680       690       700       710       

              730       740       750       760       770       780
pF1KB7 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRT
       720       730       740       750       760       770       

              790       800       810       820       830       840
pF1KB7 FTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 FTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIG
       780       790       800       810       820       830       

              850       860       870       880       890       900
pF1KB7 SNNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SNNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPI
       840       850       860       870       880       890       

              910       920       930       940       950       960
pF1KB7 RRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 RRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRP
       900       910       920       930       940       950       

              970       980       990      1000      1010      1020
pF1KB7 EARRPCLRVPCPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHCEGDRPDTVQVCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 EARRPCLRVPCPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHCEGDRPDTVQVCS
       960       970       980       990      1000      1010       

             1030      1040      1050      1060      1070      1080
pF1KB7 LPACGGNHQNSTVRADVWELGTPEGQWVPQSEPLHPINKISSTEPCTGDRSVFCQMEVLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 LPACGGNHQNSTVRADVWELGTPEGQWVPQSEPLHPINKISSTEPCTGDRSVFCQMEVLD
      1020      1030      1040      1050      1060      1070       

             1090      1100      1110      1120      1130      1140
pF1KB7 RYCSIPGYHRLCCVSCIKKASGPNPGPDPGPTSLPPFSTPGSPLPGPQDPADAAEPPGKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 RYCSIPGYHRLCCVSCIKKASGPNPGPDPGPTSLPPFSTPGSPLPGPQDPADAAEPPGKP
      1080      1090      1100      1110      1120      1130       

             1150      1160      1170      1180      1190      1200
pF1KB7 TGSEDHQHGRATQLPGALDTSSPGTQHPFAPETPIPGASWSISPTTPGGLPWGWTQTPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TGSEDHQHGRATQLPGALDTSSPGTQHPFAPETPIPGASWSISPTTPGGLPWGWTQTPTP
      1140      1150      1160      1170      1180      1190       

             1210      1220      
pF1KB7 VPEDKGQPGEDLRHPGTSLPAASPVT
       ::::::::::::::::::::::::::
NP_542 VPEDKGQPGEDLRHPGTSLPAASPVT
      1200      1210      1220   

>>XP_011537604 (OMIM: 607506) PREDICTED: A disintegrin a  (914 aa)
 initn: 6724 init1: 6724 opt: 6724  Z-score: 3520.8  bits: 663.1 E(85289): 2.3e-189
Smith-Waterman score: 6724; 100.0% identity (100.0% similar) in 914 aa overlap (313-1226:1-914)

            290       300       310       320       330       340  
pF1KB7 YVLTLMNIVDEIYHDESLGVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQ
                                     ::::::::::::::::::::::::::::::
XP_011                               MVGYRQSLSLIERGNPSRSLEQVCRWAHSQ
                                             10        20        30

            350       360       370       380       390       400  
pF1KB7 QRQDPSHAEHHDHVVFLTRQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRQDPSHAEHHDHVVFLTRQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHE
               40        50        60        70        80        90

            410       420       430       440       450       460  
pF1KB7 TGHVLGMEHDGQGNGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGHVLGMEHDGQGNGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDD
              100       110       120       130       140       150

            470       480       490       500       510       520  
pF1KB7 PFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTK
              160       170       180       190       200       210

            530       540       550       560       570       580  
pF1KB7 KGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSC
              220       230       240       250       260       270

            590       600       610       620       630       640  
pF1KB7 NNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEP
              280       290       300       310       320       330

            650       660       670       680       690       700  
pF1KB7 DDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKA
              340       350       360       370       380       390

            710       720       730       740       750       760  
pF1KB7 DDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQ
              400       410       420       430       440       450

            770       780       790       800       810       820  
pF1KB7 VTGSFILNPKGKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTGSFILNPKGKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPR
              460       470       480       490       500       510

            830       840       850       860       870       880  
pF1KB7 SSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRD
              520       530       540       550       560       570

            890       900       910       920       930       940  
pF1KB7 HHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPL
              580       590       600       610       620       630

            950       960       970       980       990      1000  
pF1KB7 SNGTHKVMPAKACAGDRPEARRPCLRVPCPAQWRLGAWSQCSATCGEGIQQRQVVCRTNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNGTHKVMPAKACAGDRPEARRPCLRVPCPAQWRLGAWSQCSATCGEGIQQRQVVCRTNA
              640       650       660       670       680       690

           1010      1020      1030      1040      1050      1060  
pF1KB7 NSLGHCEGDRPDTVQVCSLPACGGNHQNSTVRADVWELGTPEGQWVPQSEPLHPINKISS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLGHCEGDRPDTVQVCSLPACGGNHQNSTVRADVWELGTPEGQWVPQSEPLHPINKISS
              700       710       720       730       740       750

           1070      1080      1090      1100      1110      1120  
pF1KB7 TEPCTGDRSVFCQMEVLDRYCSIPGYHRLCCVSCIKKASGPNPGPDPGPTSLPPFSTPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEPCTGDRSVFCQMEVLDRYCSIPGYHRLCCVSCIKKASGPNPGPDPGPTSLPPFSTPGS
              760       770       780       790       800       810

           1130      1140      1150      1160      1170      1180  
pF1KB7 PLPGPQDPADAAEPPGKPTGSEDHQHGRATQLPGALDTSSPGTQHPFAPETPIPGASWSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPGPQDPADAAEPPGKPTGSEDHQHGRATQLPGALDTSSPGTQHPFAPETPIPGASWSI
              820       830       840       850       860       870

           1190      1200      1210      1220      
pF1KB7 SPTTPGGLPWGWTQTPTPVPEDKGQPGEDLRHPGTSLPAASPVT
       ::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPTTPGGLPWGWTQTPTPVPEDKGQPGEDLRHPGTSLPAASPVT
              880       890       900       910    

>>XP_011537603 (OMIM: 607506) PREDICTED: A disintegrin a  (914 aa)
 initn: 6724 init1: 6724 opt: 6724  Z-score: 3520.8  bits: 663.1 E(85289): 2.3e-189
Smith-Waterman score: 6724; 100.0% identity (100.0% similar) in 914 aa overlap (313-1226:1-914)

            290       300       310       320       330       340  
pF1KB7 YVLTLMNIVDEIYHDESLGVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQ
                                     ::::::::::::::::::::::::::::::
XP_011                               MVGYRQSLSLIERGNPSRSLEQVCRWAHSQ
                                             10        20        30

            350       360       370       380       390       400  
pF1KB7 QRQDPSHAEHHDHVVFLTRQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRQDPSHAEHHDHVVFLTRQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHE
               40        50        60        70        80        90

            410       420       430       440       450       460  
pF1KB7 TGHVLGMEHDGQGNGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGHVLGMEHDGQGNGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDD
              100       110       120       130       140       150

            470       480       490       500       510       520  
pF1KB7 PFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTK
              160       170       180       190       200       210

            530       540       550       560       570       580  
pF1KB7 KGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSC
              220       230       240       250       260       270

            590       600       610       620       630       640  
pF1KB7 NNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEP
              280       290       300       310       320       330

            650       660       670       680       690       700  
pF1KB7 DDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKA
              340       350       360       370       380       390

            710       720       730       740       750       760  
pF1KB7 DDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQ
              400       410       420       430       440       450

            770       780       790       800       810       820  
pF1KB7 VTGSFILNPKGKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTGSFILNPKGKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPR
              460       470       480       490       500       510

            830       840       850       860       870       880  
pF1KB7 SSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRD
              520       530       540       550       560       570

            890       900       910       920       930       940  
pF1KB7 HHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPL
              580       590       600       610       620       630

            950       960       970       980       990      1000  
pF1KB7 SNGTHKVMPAKACAGDRPEARRPCLRVPCPAQWRLGAWSQCSATCGEGIQQRQVVCRTNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNGTHKVMPAKACAGDRPEARRPCLRVPCPAQWRLGAWSQCSATCGEGIQQRQVVCRTNA
              640       650       660       670       680       690

           1010      1020      1030      1040      1050      1060  
pF1KB7 NSLGHCEGDRPDTVQVCSLPACGGNHQNSTVRADVWELGTPEGQWVPQSEPLHPINKISS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLGHCEGDRPDTVQVCSLPACGGNHQNSTVRADVWELGTPEGQWVPQSEPLHPINKISS
              700       710       720       730       740       750

           1070      1080      1090      1100      1110      1120  
pF1KB7 TEPCTGDRSVFCQMEVLDRYCSIPGYHRLCCVSCIKKASGPNPGPDPGPTSLPPFSTPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEPCTGDRSVFCQMEVLDRYCSIPGYHRLCCVSCIKKASGPNPGPDPGPTSLPPFSTPGS
              760       770       780       790       800       810

           1130      1140      1150      1160      1170      1180  
pF1KB7 PLPGPQDPADAAEPPGKPTGSEDHQHGRATQLPGALDTSSPGTQHPFAPETPIPGASWSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPGPQDPADAAEPPGKPTGSEDHQHGRATQLPGALDTSSPGTQHPFAPETPIPGASWSI
              820       830       840       850       860       870

           1190      1200      1210      1220      
pF1KB7 SPTTPGGLPWGWTQTPTPVPEDKGQPGEDLRHPGTSLPAASPVT
       ::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPTTPGGLPWGWTQTPTPVPEDKGQPGEDLRHPGTSLPAASPVT
              880       890       900       910    

>>XP_011537605 (OMIM: 607506) PREDICTED: A disintegrin a  (820 aa)
 initn: 5753 init1: 5753 opt: 5753  Z-score: 3015.8  bits: 569.5 E(85289): 3e-161
Smith-Waterman score: 5753; 99.9% identity (100.0% similar) in 813 aa overlap (1-813:1-813)

               10        20        30        40        50        60
pF1KB7 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 RQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 FTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIG
       ::::::::::::::::::::::::::::::::.                           
XP_011 FTAMGLEWEDAVEDAKESLKTSGPLPEAIAILSQAVWMLQ                    
              790       800       810       820                    

              850       860       870       880       890       900
pF1KB7 SNNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPI

>>XP_011537602 (OMIM: 607506) PREDICTED: A disintegrin a  (1056 aa)
 initn: 7548 init1: 5752 opt: 5752  Z-score: 3013.9  bits: 569.6 E(85289): 3.9e-161
Smith-Waterman score: 7212; 86.1% identity (86.1% similar) in 1226 aa overlap (1-1226:1-1056)

               10        20        30        40        50        60
pF1KB7 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 RQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 FTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIG
       ::::::::::::::::::::::::::::::::                            
XP_011 FTAMGLEWEDAVEDAKESLKTSGPLPEAIAIL----------------------------
              790       800       810                              

              850       860       870       880       890       900
pF1KB7 SNNVLLEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPI
                                                                   
XP_011 ------------------------------------------------------------
                                                                   

              910       920       930       940       950       960
pF1KB7 RRRCNQHPCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRP
                                                                   
XP_011 ------------------------------------------------------------
                                                                   

              970       980       990      1000      1010      1020
pF1KB7 EARRPCLRVPCPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHCEGDRPDTVQVCS
                             ::::::::::::::::::::::::::::::::::::::
XP_011 ----------------------CSATCGEGIQQRQVVCRTNANSLGHCEGDRPDTVQVCS
                                  820       830       840       850

             1030      1040      1050      1060      1070      1080
pF1KB7 LPACGGNHQNSTVRADVWELGTPEGQWVPQSEPLHPINKISSTEPCTGDRSVFCQMEVLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPACGGNHQNSTVRADVWELGTPEGQWVPQSEPLHPINKISSTEPCTGDRSVFCQMEVLD
              860       870       880       890       900       910

             1090      1100      1110      1120      1130      1140
pF1KB7 RYCSIPGYHRLCCVSCIKKASGPNPGPDPGPTSLPPFSTPGSPLPGPQDPADAAEPPGKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYCSIPGYHRLCCVSCIKKASGPNPGPDPGPTSLPPFSTPGSPLPGPQDPADAAEPPGKP
              920       930       940       950       960       970

             1150      1160      1170      1180      1190      1200
pF1KB7 TGSEDHQHGRATQLPGALDTSSPGTQHPFAPETPIPGASWSISPTTPGGLPWGWTQTPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGSEDHQHGRATQLPGALDTSSPGTQHPFAPETPIPGASWSISPTTPGGLPWGWTQTPTP
              980       990      1000      1010      1020      1030

             1210      1220      
pF1KB7 VPEDKGQPGEDLRHPGTSLPAASPVT
       ::::::::::::::::::::::::::
XP_011 VPEDKGQPGEDLRHPGTSLPAASPVT
             1040      1050      

>>XP_011537611 (OMIM: 607506) PREDICTED: A disintegrin a  (746 aa)
 initn: 5505 init1: 5505 opt: 5505  Z-score: 2887.2  bits: 545.6 E(85289): 4.4e-154
Smith-Waterman score: 5505; 100.0% identity (100.0% similar) in 746 aa overlap (481-1226:1-746)

              460       470       480       490       500       510
pF1KB7 RYLPSYDCLLDDPFDPAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWC
                                     ::::::::::::::::::::::::::::::
XP_011                               MDEQCRFDFGSGYQTCLAFRTFEPCKQLWC
                                             10        20        30

              520       530       540       550       560       570
pF1KB7 SHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTKFGSCSRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTKFGSCSRS
               40        50        60        70        80        90

              580       590       600       610       620       630
pF1KB7 CGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVH
              100       110       120       130       140       150

              640       650       660       670       680       690
pF1KB7 QNAKHSWVPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNAKHSWVPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVP
              160       170       180       190       200       210

              700       710       720       730       740       750
pF1KB7 VGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEAL
              220       230       240       250       260       270

              760       770       780       790       800       810
pF1KB7 EKSPHRIVVKNQVTGSFILNPKGKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKSPHRIVVKNQVTGSFILNPKGKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIA
              280       290       300       310       320       330

              820       830       840       850       860       870
pF1KB7 ILALPPTEGGPRSSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAPCSKACGGGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILALPPTEGGPRSSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAPCSKACGGGI
              340       350       360       370       380       390

              880       890       900       910       920       930
pF1KB7 QFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGACSRSCGKLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGACSRSCGKLG
              400       410       420       430       440       450

              940       950       960       970       980       990
pF1KB7 VQTRGIQCLLPLSNGTHKVMPAKACAGDRPEARRPCLRVPCPAQWRLGAWSQCSATCGEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQTRGIQCLLPLSNGTHKVMPAKACAGDRPEARRPCLRVPCPAQWRLGAWSQCSATCGEG
              460       470       480       490       500       510

             1000      1010      1020      1030      1040      1050
pF1KB7 IQQRQVVCRTNANSLGHCEGDRPDTVQVCSLPACGGNHQNSTVRADVWELGTPEGQWVPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQQRQVVCRTNANSLGHCEGDRPDTVQVCSLPACGGNHQNSTVRADVWELGTPEGQWVPQ
              520       530       540       550       560       570

             1060      1070      1080      1090      1100      1110
pF1KB7 SEPLHPINKISSTEPCTGDRSVFCQMEVLDRYCSIPGYHRLCCVSCIKKASGPNPGPDPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEPLHPINKISSTEPCTGDRSVFCQMEVLDRYCSIPGYHRLCCVSCIKKASGPNPGPDPG
              580       590       600       610       620       630

             1120      1130      1140      1150      1160      1170
pF1KB7 PTSLPPFSTPGSPLPGPQDPADAAEPPGKPTGSEDHQHGRATQLPGALDTSSPGTQHPFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTSLPPFSTPGSPLPGPQDPADAAEPPGKPTGSEDHQHGRATQLPGALDTSSPGTQHPFA
              640       650       660       670       680       690

             1180      1190      1200      1210      1220      
pF1KB7 PETPIPGASWSISPTTPGGLPWGWTQTPTPVPEDKGQPGEDLRHPGTSLPAASPVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PETPIPGASWSISPTTPGGLPWGWTQTPTPVPEDKGQPGEDLRHPGTSLPAASPVT
              700       710       720       730       740      

>>XP_011537608 (OMIM: 607506) PREDICTED: A disintegrin a  (791 aa)
 initn: 5407 init1: 5407 opt: 5407  Z-score: 2835.8  bits: 536.2 E(85289): 3.2e-151
Smith-Waterman score: 5407; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)

               10        20        30        40        50        60
pF1KB7 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 RQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRT
       :::::::::::::::::::::::::::::::::::::                       
XP_011 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIGQGSHKPDLHRHGPGVGGCGGGC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 FTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIG
                                                                   
XP_011 QGKPQDQRAPA                                                 
              790                                                  

>>XP_011537610 (OMIM: 607506) PREDICTED: A disintegrin a  (791 aa)
 initn: 5407 init1: 5407 opt: 5407  Z-score: 2835.8  bits: 536.2 E(85289): 3.2e-151
Smith-Waterman score: 5407; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)

               10        20        30        40        50        60
pF1KB7 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 RQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRT
       :::::::::::::::::::::::::::::::::::::                       
XP_011 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIGQGSHKPDLHRHGPGVGGCGGGC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 FTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIG
                                                                   
XP_011 QGKPQDQRAPA                                                 
              790                                                  

>>XP_011537609 (OMIM: 607506) PREDICTED: A disintegrin a  (791 aa)
 initn: 5407 init1: 5407 opt: 5407  Z-score: 2835.8  bits: 536.2 E(85289): 3.2e-151
Smith-Waterman score: 5407; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)

               10        20        30        40        50        60
pF1KB7 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPLRALLSYLLPLHCALCAAAGSRTPELHLSGKLSDYGVTVPCSTDFRGRFLSHVVSGP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAASAGSMVVDTPPTLPRHSSHLRVARSPLHPGGTLWPGRVGRHSLYFNVTVFGKELHLR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRPNRRLVVPGSSVEWQEDFRELFRQPLRQECVYTGGVTGMPGAAVAISNCDGLAGLIRT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 RQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQDFGPSGMQGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCAD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAWPQPPELPGINYS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRT
       :::::::::::::::::::::::::::::::::::::                       
XP_011 GTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIGQGSHKPDLHRHGPGVGGCGGGC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 FTAMGLEWEDAVEDAKESLKTSGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIG
                                                                   
XP_011 QGKPQDQRAPA                                                 
              790                                                  




1226 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 06:40:15 2016 done: Fri Nov  4 06:40:17 2016
 Total Scan time: 12.260 Total Display time:  0.310

Function used was FASTA [36.3.4 Apr, 2011]
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