FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7307, 1706 aa 1>>>pF1KB7307 1706 - 1706 aa - 1706 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.7567+/-0.00122; mu= 13.3175+/- 0.073 mean_var=153.0582+/-30.807, 0's: 0 Z-trim(106.6): 24 B-trim: 2 in 1/51 Lambda= 0.103668 statistics sampled from 9084 (9096) to 9084 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.279), width: 16 Scan time: 3.950 The best scores are: opt bits E(32554) CCDS3123.1 XRN1 gene_id:54464|Hs108|chr3 (1706) 11598 1748.1 0 CCDS63801.1 XRN1 gene_id:54464|Hs108|chr3 (1694) 10510 1585.4 0 CCDS75028.1 XRN1 gene_id:54464|Hs108|chr3 ( 459) 3050 469.3 1.3e-131 CCDS13144.1 XRN2 gene_id:22803|Hs108|chr20 ( 950) 578 99.8 4.8e-20 >>CCDS3123.1 XRN1 gene_id:54464|Hs108|chr3 (1706 aa) initn: 11598 init1: 11598 opt: 11598 Z-score: 9377.2 bits: 1748.1 E(32554): 0 Smith-Waterman score: 11598; 100.0% identity (100.0% similar) in 1706 aa overlap (1-1706:1-1706) 10 20 30 40 50 60 pF1KB7 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB7 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB7 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB7 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB7 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB7 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB7 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB7 ANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 ANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB7 TPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALF 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB7 ALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 ALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSS 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB7 HLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 HLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFEN 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB7 KEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 KEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHH 1630 1640 1650 1660 1670 1680 1690 1700 pF1KB7 KSTPISSSRRKSRKLAVNFGVSKPSE :::::::::::::::::::::::::: CCDS31 KSTPISSSRRKSRKLAVNFGVSKPSE 1690 1700 >>CCDS63801.1 XRN1 gene_id:54464|Hs108|chr3 (1694 aa) initn: 10513 init1: 9207 opt: 10510 Z-score: 8497.8 bits: 1585.4 E(32554): 0 Smith-Waterman score: 11450; 99.2% identity (99.2% similar) in 1707 aa overlap (1-1706:1-1694) 10 20 30 40 50 60 pF1KB7 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB7 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB7 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB7 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB7 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB7 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KB7 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAM-GTRMLKEILKIDGSNTVDHKNEIKQ :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: CCDS63 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQ 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB7 IANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 IANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPV 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB7 STPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 STPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAL 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KB7 FALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSS :::::::::::::::::::::::::::::::::::::::: ::::::: CCDS63 FALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPT-------------ANIMPSS 1510 1520 1530 1540 1560 1570 1580 1590 1600 1610 pF1KB7 SHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFE 1550 1560 1570 1580 1590 1600 1620 1630 1640 1650 1660 1670 pF1KB7 NKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 NKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISH 1610 1620 1630 1640 1650 1660 1680 1690 1700 pF1KB7 HKSTPISSSRRKSRKLAVNFGVSKPSE ::::::::::::::::::::::::::: CCDS63 HKSTPISSSRRKSRKLAVNFGVSKPSE 1670 1680 1690 >>CCDS75028.1 XRN1 gene_id:54464|Hs108|chr3 (459 aa) initn: 3050 init1: 3050 opt: 3050 Z-score: 2476.1 bits: 469.3 E(32554): 1.3e-131 Smith-Waterman score: 3050; 98.9% identity (99.6% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KB7 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY ::::::::::::::::::::::::::::. .:. CCDS75 EDDDLFETEFRQYKRTYYMTKMGVDVVSEYVFANAFILK 430 440 450 490 500 510 520 530 540 pF1KB7 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP >>CCDS13144.1 XRN2 gene_id:22803|Hs108|chr20 (950 aa) initn: 1648 init1: 453 opt: 578 Z-score: 473.4 bits: 99.8 E(32554): 4.8e-20 Smith-Waterman score: 1609; 40.1% identity (65.4% similar) in 684 aa overlap (1-593:1-677) 10 20 30 40 pF1KB7 MGVPKFYRWISERYP-----CLSEVVKEH---QIP-----------EFDNLYLDMNGIIH :::: :.::.:..:: :. : :: .:: :::::::::::::: CCDS13 MGVPAFFRWLSRKYPSIIVNCVEEKPKECNGVKIPVDASKPNPNDVEFDNLYLDMNGIIH 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 QCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRR :.::.: . ..:.... ::.:.. :: :..::....::.:::::::::::::.:: CCDS13 PCTHPEDKPAP--KNEDEMMVAIFEYIDRLFSIVRPRRLLYMAIDGVAPRAKMNQQRSRR 70 80 90 100 110 110 120 130 140 150 pF1KB7 FRSAKEA------EDKIKKAI-EKGETLPTEA---RFDSNCITPGTEFMARLHEHLKYFV ::..::. ...... : :: :: : :::::::::::::: : . :.:.. CCDS13 FRASKEGMEAAVEKQRVREEILAKGGFLPPEEIKERFDSNCITPGTEFMDNLAKCLRYYI 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 NMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIM ....: .:...:. .: .:::::::::..:: ..:.:.:::::.::: : :::::: CCDS13 ADRLNNDPGWKNLTVILSDASAPGEGEHKIMDYIRRQRAQPNHDPNTHHCLCGADADLIM 180 190 200 210 220 230 220 230 240 pF1KB7 LGLTSHEAHFSLLREEVR------------FG--------------GKKTQRV----CAP :::..:: .:...::: . :: ::. . . :: CCDS13 LGLATHEPNFTIIREEFKPNKPKPCGLCNQFGHEVKDCEGLPREKKGKHDELADSLPCA- 240 250 260 270 280 290 250 260 270 280 290 300 pF1KB7 EETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLH : : .:.:...:::.. :... .. : .:.:: ::::..: :.:::::.:::: :. CCDS13 -EGEFIFLRLNVLREYLERELTM--ASLPFTFDVERSIDDWVFMCFFVGNDFLPHLPSLE 300 310 320 330 340 350 310 320 330 340 350 360 pF1KB7 INHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWF : ..:. : . : ... . :::..:::..:: : . .. ... . :.. : : CCDS13 IRENAIDRLVNIYKNVVHKTGGYLTESGYVNLQRVQMIMLAVGEVEDSIFKKRKDDEDSF 360 370 380 390 400 410 370 380 390 pF1KB7 E--SKVGNKYLNE------AAGVAAEEA---RN----------YKEKKKLKGQENS---- . .: : ... .:. . .: :: . ... :.:: CCDS13 RRRQKEKRKRMKRDQPAFTPSGILTPHALGSRNSPGSQVASNPRQAAYEMRMQNNSSPSI 420 430 440 450 460 470 400 410 420 430 440 450 pF1KB7 ---LCWTALDKNEGEMITSKDNLED---ETEDDDLFETEFRQYKRTYYMTKMGVDVVSDD .:. : . . . : . :: : : .: . .:. :: .:. ::.... CCDS13 SPNTSFTS-DGSPSPLGGIKRKAEDSDSEPEPEDNVRLWEAGWKQRYYKNKFDVDAADEK 480 490 500 510 520 530 460 470 480 490 500 pF1KB7 FLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELG-KPFK : . ::... :.:.:::.: ::.::::.::::: ::...:. . :: : :::: CCDS13 FRRKVVQSYVEGLCWVLRYYYQGCASWKWYYPFHYAPFASDFEGIADMPSDFEKGTKPFK 540 550 560 570 580 590 510 520 530 540 550 560 pF1KB7 PFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFI :.:::..:.:::: :.:: ...::.. :: ::..:: :: :::::. :..:.:.::. CCDS13 PLEQLMGVFPAASGNFLPPSWRKLMSDPDSSIIDFYPEDFAIDLNGKKYAWQGVALLPFV 600 610 620 630 640 650 570 580 590 600 610 620 pF1KB7 DEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRY ::.:: :.: .: :: .:: CCDS13 DERRLRAALEEVYPDLTPEETRRNSLGGDVLFVGKHHPLHDFILELYQTGSTEPVEVPPE 660 670 680 690 700 710 1706 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:32:11 2016 done: Sat Nov 5 08:32:11 2016 Total Scan time: 3.950 Total Display time: 0.330 Function used was FASTA [36.3.4 Apr, 2011]