FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7307, 1706 aa 1>>>pF1KB7307 1706 - 1706 aa - 1706 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8269+/-0.000469; mu= 13.3772+/- 0.029 mean_var=178.9816+/-37.832, 0's: 0 Z-trim(114.4): 57 B-trim: 11 in 1/51 Lambda= 0.095867 statistics sampled from 24269 (24305) to 24269 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.285), width: 16 Scan time: 15.050 The best scores are: opt bits E(85289) NP_061874 (OMIM: 607994) 5'-3' exoribonuclease 1 i (1706) 11598 1618.3 0 XP_011511221 (OMIM: 607994) PREDICTED: 5'-3' exori (1707) 11586 1616.6 0 XP_016862129 (OMIM: 607994) PREDICTED: 5'-3' exori (1693) 10512 1468.1 0 NP_001269786 (OMIM: 607994) 5'-3' exoribonuclease (1694) 10510 1467.8 0 XP_011511224 (OMIM: 607994) PREDICTED: 5'-3' exori (1497) 10130 1415.2 0 XP_011511222 (OMIM: 607994) PREDICTED: 5'-3' exori (1669) 9977 1394.1 0 XP_016862130 (OMIM: 607994) PREDICTED: 5'-3' exori (1656) 9971 1393.3 0 XP_016862131 (OMIM: 607994) PREDICTED: 5'-3' exori (1356) 9207 1287.5 0 XP_006713736 (OMIM: 607994) PREDICTED: 5'-3' exori ( 928) 6179 868.6 0 NP_001269788 (OMIM: 607994) 5'-3' exoribonuclease ( 459) 3050 435.6 5.1e-121 XP_016883212 (OMIM: 608851) PREDICTED: 5'-3' exori ( 526) 581 94.1 3.5e-18 XP_016883213 (OMIM: 608851) PREDICTED: 5'-3' exori ( 496) 578 93.7 4.5e-18 XP_016883211 (OMIM: 608851) PREDICTED: 5'-3' exori ( 603) 578 93.8 5.2e-18 NP_036387 (OMIM: 608851) 5'-3' exoribonuclease 2 i ( 950) 578 93.9 7.3e-18 NP_001304889 (OMIM: 608851) 5'-3' exoribonuclease (1028) 578 94.0 7.7e-18 >>NP_061874 (OMIM: 607994) 5'-3' exoribonuclease 1 isofo (1706 aa) initn: 11598 init1: 11598 opt: 11598 Z-score: 8675.4 bits: 1618.3 E(85289): 0 Smith-Waterman score: 11598; 100.0% identity (100.0% similar) in 1706 aa overlap (1-1706:1-1706) 10 20 30 40 50 60 pF1KB7 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB7 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB7 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB7 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB7 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB7 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB7 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB7 ANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 ANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB7 TPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALF 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB7 ALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 ALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSS 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB7 HLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 HLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFEN 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB7 KEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 KEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHH 1630 1640 1650 1660 1670 1680 1690 1700 pF1KB7 KSTPISSSRRKSRKLAVNFGVSKPSE :::::::::::::::::::::::::: NP_061 KSTPISSSRRKSRKLAVNFGVSKPSE 1690 1700 >>XP_011511221 (OMIM: 607994) PREDICTED: 5'-3' exoribonu (1707 aa) initn: 11584 init1: 9207 opt: 11586 Z-score: 8666.5 bits: 1616.6 E(85289): 0 Smith-Waterman score: 11586; 99.9% identity (99.9% similar) in 1707 aa overlap (1-1706:1-1707) 10 20 30 40 50 60 pF1KB7 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB7 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB7 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB7 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB7 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB7 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KB7 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAM-GTRMLKEILKIDGSNTVDHKNEIKQ :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_011 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQ 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB7 IANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPV 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB7 STPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAL 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KB7 FALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSS 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KB7 SHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFE 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KB7 NKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISH 1630 1640 1650 1660 1670 1680 1680 1690 1700 pF1KB7 HKSTPISSSRRKSRKLAVNFGVSKPSE ::::::::::::::::::::::::::: XP_011 HKSTPISSSRRKSRKLAVNFGVSKPSE 1690 1700 >>XP_016862129 (OMIM: 607994) PREDICTED: 5'-3' exoribonu (1693 aa) initn: 10527 init1: 10492 opt: 10512 Z-score: 7863.7 bits: 1468.1 E(85289): 0 Smith-Waterman score: 11462; 99.2% identity (99.2% similar) in 1706 aa overlap (1-1706:1-1693) 10 20 30 40 50 60 pF1KB7 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB7 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB7 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB7 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB7 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB7 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB7 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB7 ANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB7 TPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALF 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB7 ALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSS ::::::::::::::::::::::::::::::::::::::: :::::::: XP_016 ALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPT-------------ANIMPSSS 1510 1520 1530 1540 1570 1580 1590 1600 1610 1620 pF1KB7 HLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFEN 1550 1560 1570 1580 1590 1600 1630 1640 1650 1660 1670 1680 pF1KB7 KEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHH 1610 1620 1630 1640 1650 1660 1690 1700 pF1KB7 KSTPISSSRRKSRKLAVNFGVSKPSE :::::::::::::::::::::::::: XP_016 KSTPISSSRRKSRKLAVNFGVSKPSE 1670 1680 1690 >>NP_001269786 (OMIM: 607994) 5'-3' exoribonuclease 1 is (1694 aa) initn: 10513 init1: 9207 opt: 10510 Z-score: 7862.2 bits: 1467.8 E(85289): 0 Smith-Waterman score: 11450; 99.2% identity (99.2% similar) in 1707 aa overlap (1-1706:1-1694) 10 20 30 40 50 60 pF1KB7 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB7 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB7 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB7 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB7 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB7 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KB7 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAM-GTRMLKEILKIDGSNTVDHKNEIKQ :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_001 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQ 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB7 IANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPV 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB7 STPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAL 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KB7 FALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSS :::::::::::::::::::::::::::::::::::::::: ::::::: NP_001 FALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPT-------------ANIMPSS 1510 1520 1530 1540 1560 1570 1580 1590 1600 1610 pF1KB7 SHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFE 1550 1560 1570 1580 1590 1600 1620 1630 1640 1650 1660 1670 pF1KB7 NKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISH 1610 1620 1630 1640 1650 1660 1680 1690 1700 pF1KB7 HKSTPISSSRRKSRKLAVNFGVSKPSE ::::::::::::::::::::::::::: NP_001 HKSTPISSSRRKSRKLAVNFGVSKPSE 1670 1680 1690 >>XP_011511224 (OMIM: 607994) PREDICTED: 5'-3' exoribonu (1497 aa) initn: 10128 init1: 7751 opt: 10130 Z-score: 7578.9 bits: 1415.2 E(85289): 0 Smith-Waterman score: 10130; 99.9% identity (99.9% similar) in 1497 aa overlap (211-1706:1-1497) 190 200 210 220 230 240 pF1KB7 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA :::::::::::::::::::::::::::::: XP_011 MLGLTSHEAHFSLLREEVRFGGKKTQRVCA 10 20 30 250 260 270 280 290 300 pF1KB7 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL 40 50 60 70 80 90 310 320 330 340 350 360 pF1KB7 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW 100 110 120 130 140 150 370 380 390 400 410 420 pF1KB7 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET 160 170 180 190 200 210 430 440 450 460 470 480 pF1KB7 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY 220 230 240 250 260 270 490 500 510 520 530 540 pF1KB7 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP 280 290 300 310 320 330 550 560 570 580 590 600 pF1KB7 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM 340 350 360 370 380 390 610 620 630 640 650 660 pF1KB7 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP 400 410 420 430 440 450 670 680 690 700 710 720 pF1KB7 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP 460 470 480 490 500 510 730 740 750 760 770 780 pF1KB7 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH 520 530 540 550 560 570 790 800 810 820 830 840 pF1KB7 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD 580 590 600 610 620 630 850 860 870 880 890 900 pF1KB7 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL 640 650 660 670 680 690 910 920 930 940 950 960 pF1KB7 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN 700 710 720 730 740 750 970 980 990 1000 1010 1020 pF1KB7 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN 760 770 780 790 800 810 1030 1040 1050 1060 1070 1080 pF1KB7 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV 820 830 840 850 860 870 1090 1100 1110 1120 1130 1140 pF1KB7 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF 880 890 900 910 920 930 1150 1160 1170 1180 1190 1200 pF1KB7 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS 940 950 960 970 980 990 1210 1220 1230 1240 1250 1260 pF1KB7 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL 1000 1010 1020 1030 1040 1050 1270 1280 1290 1300 1310 1320 pF1KB7 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN 1060 1070 1080 1090 1100 1110 1330 1340 1350 1360 1370 pF1KB7 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAM-GTRMLKEILKIDGSNTVDHKNEIKQ :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_011 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQ 1120 1130 1140 1150 1160 1170 1380 1390 1400 1410 1420 1430 pF1KB7 IANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPV 1180 1190 1200 1210 1220 1230 1440 1450 1460 1470 1480 1490 pF1KB7 STPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAL 1240 1250 1260 1270 1280 1290 1500 1510 1520 1530 1540 1550 pF1KB7 FALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSS 1300 1310 1320 1330 1340 1350 1560 1570 1580 1590 1600 1610 pF1KB7 SHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFE 1360 1370 1380 1390 1400 1410 1620 1630 1640 1650 1660 1670 pF1KB7 NKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISH 1420 1430 1440 1450 1460 1470 1680 1690 1700 pF1KB7 HKSTPISSSRRKSRKLAVNFGVSKPSE ::::::::::::::::::::::::::: XP_011 HKSTPISSSRRKSRKLAVNFGVSKPSE 1480 1490 >>XP_011511222 (OMIM: 607994) PREDICTED: 5'-3' exoribonu (1669 aa) initn: 11320 init1: 9207 opt: 9977 Z-score: 7463.9 bits: 1394.1 E(85289): 0 Smith-Waterman score: 11250; 97.7% identity (97.7% similar) in 1707 aa overlap (1-1706:1-1669) 10 20 30 40 50 60 pF1KB7 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB7 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB7 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB7 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB7 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB7 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KB7 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAM-GTRMLKEILKIDGSNTVDHKNEIKQ :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_011 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQ 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB7 IANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPV 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB7 STPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAL :::::::::::::::::::::::::::: XP_011 STPVTELSRICSLVGMPQPDFSFLRMPQ-------------------------------- 1450 1460 1500 1510 1520 1530 1540 1550 pF1KB7 FALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ------GSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSS 1470 1480 1490 1500 1510 1520 1560 1570 1580 1590 1600 1610 pF1KB7 SHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFE 1530 1540 1550 1560 1570 1580 1620 1630 1640 1650 1660 1670 pF1KB7 NKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISH 1590 1600 1610 1620 1630 1640 1680 1690 1700 pF1KB7 HKSTPISSSRRKSRKLAVNFGVSKPSE ::::::::::::::::::::::::::: XP_011 HKSTPISSSRRKSRKLAVNFGVSKPSE 1650 1660 >>XP_016862130 (OMIM: 607994) PREDICTED: 5'-3' exoribonu (1656 aa) initn: 11006 init1: 9207 opt: 9971 Z-score: 7459.5 bits: 1393.3 E(85289): 0 Smith-Waterman score: 11114; 97.0% identity (97.0% similar) in 1707 aa overlap (1-1706:1-1656) 10 20 30 40 50 60 pF1KB7 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB7 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB7 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB7 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB7 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB7 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KB7 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAM-GTRMLKEILKIDGSNTVDHKNEIKQ :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_016 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQ 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB7 IANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPV 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB7 STPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAL :::::::::::::::::::::::::::: XP_016 STPVTELSRICSLVGMPQPDFSFLRMPQ-------------------------------- 1450 1460 1500 1510 1520 1530 1540 1550 pF1KB7 FALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSS :::::::::::::::::::::::::::::::::: ::::::: XP_016 ------GSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPT-------------ANIMPSS 1470 1480 1490 1500 1560 1570 1580 1590 1600 1610 pF1KB7 SHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFE 1510 1520 1530 1540 1550 1560 1620 1630 1640 1650 1660 1670 pF1KB7 NKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISH 1570 1580 1590 1600 1610 1620 1680 1690 1700 pF1KB7 HKSTPISSSRRKSRKLAVNFGVSKPSE ::::::::::::::::::::::::::: XP_016 HKSTPISSSRRKSRKLAVNFGVSKPSE 1630 1640 1650 >>XP_016862131 (OMIM: 607994) PREDICTED: 5'-3' exoribonu (1356 aa) initn: 9207 init1: 9207 opt: 9207 Z-score: 6889.6 bits: 1287.5 E(85289): 0 Smith-Waterman score: 9207; 100.0% identity (100.0% similar) in 1354 aa overlap (1-1354:1-1354) 10 20 30 40 50 60 pF1KB7 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB7 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB7 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB7 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB7 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB7 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB7 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQI :::::::::::::::::::::::::::::::::: XP_016 FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKR 1330 1340 1350 1390 1400 1410 1420 1430 1440 pF1KB7 ANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVS >>XP_006713736 (OMIM: 607994) PREDICTED: 5'-3' exoribonu (928 aa) initn: 6179 init1: 6179 opt: 6179 Z-score: 4628.5 bits: 868.6 E(85289): 0 Smith-Waterman score: 6179; 99.9% identity (100.0% similar) in 906 aa overlap (1-906:1-906) 10 20 30 40 50 60 pF1KB7 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN :::::. XP_006 IQNQHEKERGAEKFCLQILSKKRGNGSK 910 920 >>NP_001269788 (OMIM: 607994) 5'-3' exoribonuclease 1 is (459 aa) initn: 3050 init1: 3050 opt: 3050 Z-score: 2293.7 bits: 435.6 E(85289): 5.1e-121 Smith-Waterman score: 3050; 98.9% identity (99.6% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KB7 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY ::::::::::::::::::::::::::::. .:. NP_001 EDDDLFETEFRQYKRTYYMTKMGVDVVSEYVFANAFILK 430 440 450 490 500 510 520 530 540 pF1KB7 YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP 1706 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:32:12 2016 done: Sat Nov 5 08:32:14 2016 Total Scan time: 15.050 Total Display time: 1.010 Function used was FASTA [36.3.4 Apr, 2011]