Result of FASTA (omim) for
pF1KB7316
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7316, 1097 aa
1>>>pF1KB7316 1097 - 1097 aa - 1097 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8231+/-0.000526; mu= 13.9925+/- 0.032
mean_var=105.3638+/-22.094, 0's: 0 Z-trim(110.0): 285 B-trim: 567 in 2/53
Lambda= 0.124948
statistics sampled from 17921 (18290) to 17921 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.571), E-opt: 0.2 (0.214), width: 16
Scan time: 10.650
The best scores are: opt bits E(85289)
NP_001121143 (OMIM: 151443,601559) leukemia inhibi (1097) 7423 1350.2 0
XP_011512344 (OMIM: 151443,601559) PREDICTED: leuk (1097) 7423 1350.2 0
XP_016864952 (OMIM: 151443,601559) PREDICTED: leuk (1097) 7423 1350.2 0
XP_011512342 (OMIM: 151443,601559) PREDICTED: leuk (1097) 7423 1350.2 0
NP_002301 (OMIM: 151443,601559) leukemia inhibitor (1097) 7423 1350.2 0
XP_016864951 (OMIM: 151443,601559) PREDICTED: leuk (1115) 7423 1350.2 0
NP_001310435 (OMIM: 105250,601743) oncostatin-M-sp ( 980) 1499 282.3 9.5e-75
XP_005248441 (OMIM: 105250,601743) PREDICTED: onco ( 980) 1499 282.3 9.5e-75
XP_011512463 (OMIM: 105250,601743) PREDICTED: onco ( 800) 1468 276.7 3.9e-73
NP_001310434 (OMIM: 105250,601743) oncostatin-M-sp ( 979) 1200 228.4 1.6e-58
NP_003990 (OMIM: 105250,601743) oncostatin-M-speci ( 979) 1200 228.4 1.6e-58
XP_016865508 (OMIM: 105250,601743) PREDICTED: onco ( 799) 1176 224.0 2.7e-57
XP_005248443 (OMIM: 105250,601743) PREDICTED: onco ( 582) 982 189.0 6.9e-47
XP_016865509 (OMIM: 105250,601743) PREDICTED: onco ( 647) 963 185.6 8.1e-46
NP_001310436 (OMIM: 105250,601743) oncostatin-M-sp ( 581) 777 152.0 9.2e-36
XP_005248444 (OMIM: 105250,601743) PREDICTED: onco ( 581) 777 152.0 9.2e-36
NP_002175 (OMIM: 600694) interleukin-6 receptor su ( 918) 562 113.4 6.3e-24
XP_011541445 (OMIM: 609510,613955) PREDICTED: inte ( 662) 497 101.6 1.6e-20
NP_001229567 (OMIM: 609510,613955) interleukin-31 ( 662) 497 101.6 1.6e-20
NP_001229566 (OMIM: 609510,613955) interleukin-31 ( 681) 497 101.6 1.6e-20
XP_011541444 (OMIM: 609510,613955) PREDICTED: inte ( 732) 490 100.4 4.2e-20
NP_001229565 (OMIM: 609510,613955) interleukin-31 ( 745) 490 100.4 4.3e-20
NP_620586 (OMIM: 609510,613955) interleukin-31 rec ( 764) 490 100.4 4.4e-20
NP_001284499 (OMIM: 609510,613955) interleukin-31 ( 582) 465 95.8 7.9e-19
NP_001177910 (OMIM: 600694) interleukin-6 receptor ( 857) 421 88.0 2.7e-16
XP_011541446 (OMIM: 609510,613955) PREDICTED: inte ( 622) 415 86.8 4.3e-16
NP_001229568 (OMIM: 609510,613955) interleukin-31 ( 622) 415 86.8 4.3e-16
XP_011541447 (OMIM: 609510,613955) PREDICTED: inte ( 594) 401 84.3 2.4e-15
NP_001284501 (OMIM: 609510,613955) interleukin-31 ( 440) 390 82.2 7.3e-15
XP_016856693 (OMIM: 601642) PREDICTED: interleukin ( 498) 376 79.7 4.6e-14
NP_001245144 (OMIM: 601642) interleukin-12 recepto ( 776) 376 79.8 6.8e-14
XP_006710680 (OMIM: 601642) PREDICTED: interleukin ( 776) 376 79.8 6.8e-14
XP_011539686 (OMIM: 601642) PREDICTED: interleukin ( 809) 376 79.8 7e-14
XP_011539685 (OMIM: 601642) PREDICTED: interleukin ( 862) 373 79.3 1.1e-13
XP_005270882 (OMIM: 601642) PREDICTED: interleukin ( 862) 373 79.3 1.1e-13
XP_005270884 (OMIM: 601642) PREDICTED: interleukin ( 862) 373 79.3 1.1e-13
XP_005270885 (OMIM: 601642) PREDICTED: interleukin ( 862) 373 79.3 1.1e-13
NP_001550 (OMIM: 601642) interleukin-12 receptor s ( 862) 373 79.3 1.1e-13
NP_001310433 (OMIM: 105250,601743) oncostatin-M-sp ( 342) 343 73.7 2.1e-12
NP_001161827 (OMIM: 105250,601743) oncostatin-M-sp ( 342) 343 73.7 2.1e-12
XP_016856691 (OMIM: 601642) PREDICTED: interleukin ( 700) 341 73.5 4.9e-12
NP_001245145 (OMIM: 601642) interleukin-12 recepto ( 635) 339 73.1 5.8e-12
NP_001306162 (OMIM: 601642) interleukin-12 recepto ( 659) 339 73.1 6e-12
XP_016856692 (OMIM: 601642) PREDICTED: interleukin ( 659) 339 73.1 6e-12
NP_001245143 (OMIM: 601642) interleukin-12 recepto ( 659) 339 73.1 6e-12
XP_016864931 (OMIM: 600694) PREDICTED: interleukin ( 617) 327 70.9 2.5e-11
XP_011539051 (OMIM: 138971,162830,617014) PREDICTE ( 862) 301 66.3 8.7e-10
NP_758519 (OMIM: 138971,162830,617014) granulocyte ( 783) 295 65.2 1.7e-09
XP_005270550 (OMIM: 138971,162830,617014) PREDICTE ( 835) 295 65.2 1.8e-09
NP_000751 (OMIM: 138971,162830,617014) granulocyte ( 836) 295 65.2 1.8e-09
>>NP_001121143 (OMIM: 151443,601559) leukemia inhibitory (1097 aa)
initn: 7423 init1: 7423 opt: 7423 Z-score: 7233.4 bits: 1350.2 E(85289): 0
Smith-Waterman score: 7423; 100.0% identity (100.0% similar) in 1097 aa overlap (1-1097:1-1097)
10 20 30 40 50 60
pF1KB7 MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 STSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 IRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 LVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 STILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 NVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 TWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 NDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 WCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 ELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 SDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAI
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 LIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 NPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 PAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB7 DLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKS
1030 1040 1050 1060 1070 1080
1090
pF1KB7 NGGGWSFTNFFQNKPND
:::::::::::::::::
NP_001 NGGGWSFTNFFQNKPND
1090
>>XP_011512344 (OMIM: 151443,601559) PREDICTED: leukemia (1097 aa)
initn: 7423 init1: 7423 opt: 7423 Z-score: 7233.4 bits: 1350.2 E(85289): 0
Smith-Waterman score: 7423; 100.0% identity (100.0% similar) in 1097 aa overlap (1-1097:1-1097)
10 20 30 40 50 60
pF1KB7 MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 STSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 IRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 LVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 STILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 NVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 TWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 NDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 WCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 ELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 SDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAI
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 LIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 NPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 PAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB7 DLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKS
1030 1040 1050 1060 1070 1080
1090
pF1KB7 NGGGWSFTNFFQNKPND
:::::::::::::::::
XP_011 NGGGWSFTNFFQNKPND
1090
>>XP_016864952 (OMIM: 151443,601559) PREDICTED: leukemia (1097 aa)
initn: 7423 init1: 7423 opt: 7423 Z-score: 7233.4 bits: 1350.2 E(85289): 0
Smith-Waterman score: 7423; 100.0% identity (100.0% similar) in 1097 aa overlap (1-1097:1-1097)
10 20 30 40 50 60
pF1KB7 MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 STSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 IRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 LVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 STILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 NVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 TWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 NDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 WCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 ELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 SDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAI
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 LIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 NPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 PAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB7 DLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKS
1030 1040 1050 1060 1070 1080
1090
pF1KB7 NGGGWSFTNFFQNKPND
:::::::::::::::::
XP_016 NGGGWSFTNFFQNKPND
1090
>>XP_011512342 (OMIM: 151443,601559) PREDICTED: leukemia (1097 aa)
initn: 7423 init1: 7423 opt: 7423 Z-score: 7233.4 bits: 1350.2 E(85289): 0
Smith-Waterman score: 7423; 100.0% identity (100.0% similar) in 1097 aa overlap (1-1097:1-1097)
10 20 30 40 50 60
pF1KB7 MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 STSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 IRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 LVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 STILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 NVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 TWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 NDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 WCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 ELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 SDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAI
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 LIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 NPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 PAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB7 DLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKS
1030 1040 1050 1060 1070 1080
1090
pF1KB7 NGGGWSFTNFFQNKPND
:::::::::::::::::
XP_011 NGGGWSFTNFFQNKPND
1090
>>NP_002301 (OMIM: 151443,601559) leukemia inhibitory fa (1097 aa)
initn: 7423 init1: 7423 opt: 7423 Z-score: 7233.4 bits: 1350.2 E(85289): 0
Smith-Waterman score: 7423; 100.0% identity (100.0% similar) in 1097 aa overlap (1-1097:1-1097)
10 20 30 40 50 60
pF1KB7 MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 STSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 STSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 IRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 LVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 STILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 STILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 NVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 TWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 NDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 WCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 ELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 SDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAI
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 LIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 NPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 PAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB7 DLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKS
1030 1040 1050 1060 1070 1080
1090
pF1KB7 NGGGWSFTNFFQNKPND
:::::::::::::::::
NP_002 NGGGWSFTNFFQNKPND
1090
>>XP_016864951 (OMIM: 151443,601559) PREDICTED: leukemia (1115 aa)
initn: 7423 init1: 7423 opt: 7423 Z-score: 7233.3 bits: 1350.2 E(85289): 0
Smith-Waterman score: 7423; 100.0% identity (100.0% similar) in 1097 aa overlap (1-1097:19-1115)
10 20 30 40
pF1KB7 MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQV
::::::::::::::::::::::::::::::::::::::::::
XP_016 MPEAALWKPRGRTDCIAQMMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 NSQKKGAPHDLKCVTNNLQVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSQKKGAPHDLKCVTNNLQVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 LSHGDYEITINSLHDFGSSTSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSHGDYEITINSLHDFGSSTSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 VFPHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFPHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRC
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB7 YIDNLHFSGLEEWSDWSPVKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIDNLHFSGLEEWSDWSPVKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB7 GHTNCPLIHLDGENVAIKIRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHTNCPLIHLDGENVAIKIRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCE
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB7 THDLKEIICSWNPGRVTALVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THDLKEIICSWNPGRVTALVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPN
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB7 QEIYNFTLNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEIYNFTLNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKI
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB7 NFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKW
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB7 SNKKQHLTTEASPSKGPDTWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNKKQHLTTEASPSKGPDTWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQ
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB7 SLSEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKG
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB7 ILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLY
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB7 GCRNQGYQLLRSMIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCRNQGYQLLRSMIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFY
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB7 FGKGERDTSKMRVLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGKGERDTSKMRVLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPE
790 800 810 820 830 840
830 840 850 860 870 880
pF1KB7 KSMYVVTKENSVGLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSMYVVTKENSVGLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKAL
850 860 870 880 890 900
890 900 910 920 930 940
pF1KB7 QFQKSVCEGSSALKTLEMNPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFQKSVCEGSSALKTLEMNPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPE
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KB7 NHVVVSYCPPIIEEEIPNPAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHVVVSYCPPIIEEEIPNPAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYK
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KB7 PQMHLPINSTVEDIAAEEDLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQMHLPINSTVEDIAAEEDLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCS
1030 1040 1050 1060 1070 1080
1070 1080 1090
pF1KB7 INSRQFLIPPKDEDSPKSNGGGWSFTNFFQNKPND
:::::::::::::::::::::::::::::::::::
XP_016 INSRQFLIPPKDEDSPKSNGGGWSFTNFFQNKPND
1090 1100 1110
>>NP_001310435 (OMIM: 105250,601743) oncostatin-M-specif (980 aa)
initn: 966 init1: 204 opt: 1499 Z-score: 1462.9 bits: 282.3 E(85289): 9.5e-75
Smith-Waterman score: 1506; 31.8% identity (63.5% similar) in 916 aa overlap (135-1010:30-917)
110 120 130 140 150 160
pF1KB7 HGDYEITINSLHDFGSSTSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVF
.: :: :..:.. . ..:.:.:. .. .
NP_001 MALFAVFQTTFFLTLLSLRTYQSEVLAERLPLTPVSLKVSTNSTRQSLHLQWTVHNLPY
10 20 30 40 50
170 180 190 200 210 220
pF1KB7 PHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYI
.. .....:.. : :. ... . ...::.. ...:: ::: :..::::: :::.:. .
NP_001 HQELKMVFQIQISRIETSNVIWVGNYSTTVKWNQVLH-WSWESELPLECATHFVRIKSLV
60 70 80 90 100 110
230 240 250 260 270 280
pF1KB7 DNLHFSGLEEWSDWSPVKNISWIPDSQTK----VFPQDKVILVGSDITFCCVSQEKVLSA
:. .: . ::.:: ...: . :: . :::.::.. :...:.: ::.. . .
NP_001 DDAKFPEPNFWSNWSSWEEVS-VQDSTGQDILFVFPKDKLVEEGTNVTICYVSRN-IQNN
120 130 140 150 160 170
290 300 310 320 330
pF1KB7 LIGHTNCPLIH---LDGENVAIKIRNISVSASSGTNVVF-TTEDNIF----GTVIFAGYP
. . . :: :: . .:... .. ..:::. ... :. : :.:..
NP_001 VSCYLEGKQIHGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKV
180 190 200 210 220 230
340 350 360 370 380 390
pF1KB7 PDTPQQLNCETHDLKEIICSWNPGRVTALVGPR--ATSYTLVESFSGKYVRLKRAEAPTN
. :....:::.:.: . :.:.:: ::: . . :::: :::::. :. . :
NP_001 LEEPKDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGE----KKLCTHKN
240 250 260 270 280 290
400 410 420 430 440 450
pF1KB7 ESYQLLFQMLPNQEIYNFTLNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDINSTAVK
. : .:: ::::: :.: : . . .:: :.:..:: .: : . ...:.: .
NP_001 WCNWQITQ--DSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAI
300 310 320 330 340 350
460 470 480 490 500 510
pF1KB7 LSWHLPGNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIR
..:.. . ....::.::.. .....: ::.:: :. :. :..:.: : : :.:
NP_001 MTWKVHSIRNNFTYLCQIELHGEGKMMQQYNVSIK--VNGEYF--LSELEPATEYMARVR
360 370 380 390 400
520 530 540 550 560
pF1KB7 CSTET-FWKWSKWSNKKQHLTT-EASPSKGPDTWREWSSDGKN--LIIYWKPLPINEANG
:. . :::::.::. :..:: ::.::..::.:: : . : . ..:::: .:::
NP_001 CADASHFWKWSEWSG--QNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFWKPLSKLHANG
410 420 430 440 450 460
570 580 590 600 610 620
pF1KB7 KILSYNVSCSS-DEETQS-LSEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSKIA-S
::: ::: . :. ..: : :: : ..... ::. .: : :.:.::::.:: : :. :
NP_001 KILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIANNSVGASPASVIVIS
470 480 490 500 510 520
630 640 650 660 670 680
pF1KB7 MEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTE
. : ... :...: :. :.:. .:. . ::. ::. ... ..:..: :.:
NP_001 ADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTS
530 540 550 560 570 580
690 700 710 720 730 740
pF1KB7 TVIESDEFRPGIRYNFFLYGCRNQGYQ-LLRSMIGYIEELAPIVAPNFTVEDTSADSILV
::: .: ::::.::.: .:: .. ::.. :: .:::: :. :. .. :. .
NP_001 TVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTL
590 600 610 620 630 640
750 760 770 780 790
pF1KB7 KWEDIPVEELRGFLRGYLFYFGKGERDTS---KMRVLESGRSDIKVKNITDISQKTLRIA
.:.: .: ::..:: :. . :. . :: .: : : : . .:.: .
NP_001 SWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYK-IDNPEEKALIVD
650 660 670 680 690 700
800 810 820 830 840 850
pF1KB7 DLQGKTSYHLVLRAYTDGGVGPEKSMY-VVTKENSVGLIIAILIPVAVAVIVGVVTSILC
.:. .. :.. . .:..: :: .. :.: .. ...: ::.:.. :.. .: .:
NP_001 NLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLIMV---MC
710 720 730 740 750 760
860 870 880 890 900 910
pF1KB7 YRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEMNPCTPNNVEVLE----TR
: : .::::: :::::.: . . :.. : . . : .... : :. .::. :.
NP_001 YLKSQWIKETCYPDIPDPYKSSILSLIK--FKENPHLIIMNVSDCIPDAIEVVSKPEGTK
770 780 790 800 810
920 930 940 950 960
pF1KB7 SAF----PKIEDTEIISP--VAERPEDRSDAEPENHVVVSYCPPIIEEEIPNPAADEAGG
: .. .::. .: . : ... . : . : .:. : ::...:.
NP_001 IQFLGTRKSLTETELTKPNYLYLLPTEKNHSGPGPCI----C---FENLTYNQAASDSGS
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KB7 TAQV-IYIDVQSMYQPQAKPE---EEQENDPVGGAGYKPQMHLPINSTVEDIAAEEDLDK
..: . . :: ...:: . :.. ... : : . .:
NP_001 CGHVPVSPKAPSMLGLMTSPENVLKALEKNYMNSLGEIPAGETSLNYVSQLASPMFGDKD
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KB7 TAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKSNGGG
NP_001 SLPTNPVEAPHCSEYKMQMAVSLRLALPPPTENSSLSSITLLDPGEHYC
940 950 960 970 980
>>XP_005248441 (OMIM: 105250,601743) PREDICTED: oncostat (980 aa)
initn: 966 init1: 204 opt: 1499 Z-score: 1462.9 bits: 282.3 E(85289): 9.5e-75
Smith-Waterman score: 1506; 31.8% identity (63.5% similar) in 916 aa overlap (135-1010:30-917)
110 120 130 140 150 160
pF1KB7 HGDYEITINSLHDFGSSTSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVF
.: :: :..:.. . ..:.:.:. .. .
XP_005 MALFAVFQTTFFLTLLSLRTYQSEVLAERLPLTPVSLKVSTNSTRQSLHLQWTVHNLPY
10 20 30 40 50
170 180 190 200 210 220
pF1KB7 PHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYI
.. .....:.. : :. ... . ...::.. ...:: ::: :..::::: :::.:. .
XP_005 HQELKMVFQIQISRIETSNVIWVGNYSTTVKWNQVLH-WSWESELPLECATHFVRIKSLV
60 70 80 90 100 110
230 240 250 260 270 280
pF1KB7 DNLHFSGLEEWSDWSPVKNISWIPDSQTK----VFPQDKVILVGSDITFCCVSQEKVLSA
:. .: . ::.:: ...: . :: . :::.::.. :...:.: ::.. . .
XP_005 DDAKFPEPNFWSNWSSWEEVS-VQDSTGQDILFVFPKDKLVEEGTNVTICYVSRN-IQNN
120 130 140 150 160 170
290 300 310 320 330
pF1KB7 LIGHTNCPLIH---LDGENVAIKIRNISVSASSGTNVVF-TTEDNIF----GTVIFAGYP
. . . :: :: . .:... .. ..:::. ... :. : :.:..
XP_005 VSCYLEGKQIHGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKV
180 190 200 210 220 230
340 350 360 370 380 390
pF1KB7 PDTPQQLNCETHDLKEIICSWNPGRVTALVGPR--ATSYTLVESFSGKYVRLKRAEAPTN
. :....:::.:.: . :.:.:: ::: . . :::: :::::. :. . :
XP_005 LEEPKDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGE----KKLCTHKN
240 250 260 270 280 290
400 410 420 430 440 450
pF1KB7 ESYQLLFQMLPNQEIYNFTLNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDINSTAVK
. : .:: ::::: :.: : . . .:: :.:..:: .: : . ...:.: .
XP_005 WCNWQITQ--DSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAI
300 310 320 330 340 350
460 470 480 490 500 510
pF1KB7 LSWHLPGNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIR
..:.. . ....::.::.. .....: ::.:: :. :. :..:.: : : :.:
XP_005 MTWKVHSIRNNFTYLCQIELHGEGKMMQQYNVSIK--VNGEYF--LSELEPATEYMARVR
360 370 380 390 400
520 530 540 550 560
pF1KB7 CSTET-FWKWSKWSNKKQHLTT-EASPSKGPDTWREWSSDGKN--LIIYWKPLPINEANG
:. . :::::.::. :..:: ::.::..::.:: : . : . ..:::: .:::
XP_005 CADASHFWKWSEWSG--QNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFWKPLSKLHANG
410 420 430 440 450 460
570 580 590 600 610 620
pF1KB7 KILSYNVSCSS-DEETQS-LSEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSKIA-S
::: ::: . :. ..: : :: : ..... ::. .: : :.:.::::.:: : :. :
XP_005 KILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIANNSVGASPASVIVIS
470 480 490 500 510 520
630 640 650 660 670 680
pF1KB7 MEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTE
. : ... :...: :. :.:. .:. . ::. ::. ... ..:..: :.:
XP_005 ADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTS
530 540 550 560 570 580
690 700 710 720 730 740
pF1KB7 TVIESDEFRPGIRYNFFLYGCRNQGYQ-LLRSMIGYIEELAPIVAPNFTVEDTSADSILV
::: .: ::::.::.: .:: .. ::.. :: .:::: :. :. .. :. .
XP_005 TVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTL
590 600 610 620 630 640
750 760 770 780 790
pF1KB7 KWEDIPVEELRGFLRGYLFYFGKGERDTS---KMRVLESGRSDIKVKNITDISQKTLRIA
.:.: .: ::..:: :. . :. . :: .: : : : . .:.: .
XP_005 SWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYK-IDNPEEKALIVD
650 660 670 680 690 700
800 810 820 830 840 850
pF1KB7 DLQGKTSYHLVLRAYTDGGVGPEKSMY-VVTKENSVGLIIAILIPVAVAVIVGVVTSILC
.:. .. :.. . .:..: :: .. :.: .. ...: ::.:.. :.. .: .:
XP_005 NLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLIMV---MC
710 720 730 740 750 760
860 870 880 890 900 910
pF1KB7 YRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEMNPCTPNNVEVLE----TR
: : .::::: :::::.: . . :.. : . . : .... : :. .::. :.
XP_005 YLKSQWIKETCYPDIPDPYKSSILSLIK--FKENPHLIIMNVSDCIPDAIEVVSKPEGTK
770 780 790 800 810
920 930 940 950 960
pF1KB7 SAF----PKIEDTEIISP--VAERPEDRSDAEPENHVVVSYCPPIIEEEIPNPAADEAGG
: .. .::. .: . : ... . : . : .:. : ::...:.
XP_005 IQFLGTRKSLTETELTKPNYLYLLPTEKNHSGPGPCI----C---FENLTYNQAASDSGS
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KB7 TAQV-IYIDVQSMYQPQAKPE---EEQENDPVGGAGYKPQMHLPINSTVEDIAAEEDLDK
..: . . :: ...:: . :.. ... : : . .:
XP_005 CGHVPVSPKAPSMLGLMTSPENVLKALEKNYMNSLGEIPAGETSLNYVSQLASPMFGDKD
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KB7 TAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKSNGGG
XP_005 SLPTNPVEAPHCSEYKMQMAVSLRLALPPPTENSSLSSITLLDPGEHYC
940 950 960 970 980
>>XP_011512463 (OMIM: 105250,601743) PREDICTED: oncostat (800 aa)
initn: 966 init1: 204 opt: 1468 Z-score: 1434.1 bits: 276.7 E(85289): 3.9e-73
Smith-Waterman score: 1468; 33.9% identity (65.9% similar) in 778 aa overlap (135-886:30-788)
110 120 130 140 150 160
pF1KB7 HGDYEITINSLHDFGSSTSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVF
.: :: :..:.. . ..:.:.:. .. .
XP_011 MALFAVFQTTFFLTLLSLRTYQSEVLAERLPLTPVSLKVSTNSTRQSLHLQWTVHNLPY
10 20 30 40 50
170 180 190 200 210 220
pF1KB7 PHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYI
.. .....:.. : :. ... . ...::.. ...:: ::: :..::::: :::.:. .
XP_011 HQELKMVFQIQISRIETSNVIWVGNYSTTVKWNQVLH-WSWESELPLECATHFVRIKSLV
60 70 80 90 100 110
230 240 250 260 270 280
pF1KB7 DNLHFSGLEEWSDWSPVKNISWIPDSQTK----VFPQDKVILVGSDITFCCVSQEKVLSA
:. .: . ::.:: ...: . :: . :::.::.. :...:.: ::.. . .
XP_011 DDAKFPEPNFWSNWSSWEEVS-VQDSTGQDILFVFPKDKLVEEGTNVTICYVSRN-IQNN
120 130 140 150 160 170
290 300 310 320 330
pF1KB7 LIGHTNCPLIH---LDGENVAIKIRNISVSASSGTNVVF-TTEDNIF----GTVIFAGYP
. . . :: :: . .:... .. ..:::. ... :. : :.:..
XP_011 VSCYLEGKQIHGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKV
180 190 200 210 220 230
340 350 360 370 380 390
pF1KB7 PDTPQQLNCETHDLKEIICSWNPGRVTALVGPR--ATSYTLVESFSGKYVRLKRAEAPTN
. :....:::.:.: . :.:.:: ::: . . :::: :::::. :. . :
XP_011 LEEPKDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGE----KKLCTHKN
240 250 260 270 280 290
400 410 420 430 440 450
pF1KB7 ESYQLLFQMLPNQEIYNFTLNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDINSTAVK
. : .:: ::::: :.: : . . .:: :.:..:: .: : . ...:.: .
XP_011 WCNWQITQ--DSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAI
300 310 320 330 340 350
460 470 480 490 500 510
pF1KB7 LSWHLPGNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIR
..:.. . ....::.::.. .....: ::.:: :. :. :..:.: : : :.:
XP_011 MTWKVHSIRNNFTYLCQIELHGEGKMMQQYNVSIK--VNGEYF--LSELEPATEYMARVR
360 370 380 390 400
520 530 540 550 560
pF1KB7 CSTET-FWKWSKWSNKKQHLTT-EASPSKGPDTWREWSSDGKN--LIIYWKPLPINEANG
:. . :::::.::. :..:: ::.::..::.:: : . : . ..:::: .:::
XP_011 CADASHFWKWSEWSG--QNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFWKPLSKLHANG
410 420 430 440 450 460
570 580 590 600 610 620
pF1KB7 KILSYNVSCSS-DEETQS-LSEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSKIA-S
::: ::: . :. ..: : :: : ..... ::. .: : :.:.::::.:: : :. :
XP_011 KILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIANNSVGASPASVIVIS
470 480 490 500 510 520
630 640 650 660 670 680
pF1KB7 MEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTE
. : ... :...: :. :.:. .:. . ::. ::. ... ..:..: :.:
XP_011 ADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTS
530 540 550 560 570 580
690 700 710 720 730 740
pF1KB7 TVIESDEFRPGIRYNFFLYGCRNQGYQ-LLRSMIGYIEELAPIVAPNFTVEDTSADSILV
::: .: ::::.::.: .:: .. ::.. :: .:::: :. :. .. :. .
XP_011 TVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTL
590 600 610 620 630 640
750 760 770 780 790
pF1KB7 KWEDIPVEELRGFLRGYLFYFGKGERDTS---KMRVLESGRSDIKVKNITDISQKTLRIA
.:.: .: ::..:: :. . :. . :: .: : : : . .:.: .
XP_011 SWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYK-IDNPEEKALIVD
650 660 670 680 690 700
800 810 820 830 840 850
pF1KB7 DLQGKTSYHLVLRAYTDGGVGPEKSMY-VVTKENSVGLIIAILIPVAVAVIVGVVTSILC
.:. .. :.. . .:..: :: .. :.: .. ...: ::.:.. :.. .: .:
XP_011 NLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLIMV---MC
710 720 730 740 750 760
860 870 880 890 900 910
pF1KB7 YRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEMNPCTPNNVEVLETRSAFP
: : .::::: :::::.: . . :.. :
XP_011 YLKSQWIKETCYPDIPDPYKSSILSLIKFKISSKVWLNRR
770 780 790 800
>>NP_001310434 (OMIM: 105250,601743) oncostatin-M-specif (979 aa)
initn: 921 init1: 178 opt: 1200 Z-score: 1171.7 bits: 228.4 E(85289): 1.6e-58
Smith-Waterman score: 1492; 31.8% identity (63.4% similar) in 916 aa overlap (135-1010:30-916)
110 120 130 140 150 160
pF1KB7 HGDYEITINSLHDFGSSTSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVF
.: :: :..:.. . ..:.:.:. .. .
NP_001 MALFAVFQTTFFLTLLSLRTYQSEVLAERLPLTPVSLKVSTNSTRQSLHLQWTVHNLPY
10 20 30 40 50
170 180 190 200 210 220
pF1KB7 PHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYI
.. .....:.. : :. ... . ...::.. ...:: ::: :..::::: :::.:. .
NP_001 HQELKMVFQIQISRIETSNVIWVGNYSTTVKWNQVLH-WSWESELPLECATHFVRIKSLV
60 70 80 90 100 110
230 240 250 260 270 280
pF1KB7 DNLHFSGLEEWSDWSPVKNISWIPDSQTK----VFPQDKVILVGSDITFCCVSQEKVLSA
:. .: . ::.:: ...: . :: . :::.::.. :...:.: ::.. . .
NP_001 DDAKFPEPNFWSNWSSWEEVS-VQDSTGQDILFVFPKDKLVEEGTNVTICYVSRN-IQNN
120 130 140 150 160 170
290 300 310 320 330
pF1KB7 LIGHTNCPLIH---LDGENVAIKIRNISVSASSGTNVVF-TTEDNIF----GTVIFAGYP
. . . :: :: . .:... .. ..:::. ... :. : :.:..
NP_001 VSCYLEGKQIHGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKV
180 190 200 210 220 230
340 350 360 370 380 390
pF1KB7 PDTPQQLNCETHDLKEIICSWNPGRVTALVGPR--ATSYTLVESFSGKYVRLKRAEAPTN
. :....:::.:.: . :.:.:: ::: . . :::: :::::. :. . :
NP_001 LEEPKDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGE----KKLCTHKN
240 250 260 270 280 290
400 410 420 430 440 450
pF1KB7 ESYQLLFQMLPNQEIYNFTLNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDINSTAVK
. : .:: ::::: :.: : . . .:: :.:..:: .: : . ...:.: .
NP_001 WCNWQITQ--DSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAI
300 310 320 330 340 350
460 470 480 490 500 510
pF1KB7 LSWHLPGNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIR
..:.. . ....::.::.. .... : ::.:: :. :. :..:.: : : :.:
NP_001 MTWKVHSIRNNFTYLCQIELHGEGKMM-QYNVSIK--VNGEYF--LSELEPATEYMARVR
360 370 380 390 400
520 530 540 550 560
pF1KB7 CSTET-FWKWSKWSNKKQHLTT-EASPSKGPDTWREWSSDGKN--LIIYWKPLPINEANG
:. . :::::.::. :..:: ::.::..::.:: : . : . ..:::: .:::
NP_001 CADASHFWKWSEWSG--QNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFWKPLSKLHANG
410 420 430 440 450 460
570 580 590 600 610 620
pF1KB7 KILSYNVSCSS-DEETQS-LSEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSKIA-S
::: ::: . :. ..: : :: : ..... ::. .: : :.:.::::.:: : :. :
NP_001 KILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIANNSVGASPASVIVIS
470 480 490 500 510 520
630 640 650 660 670 680
pF1KB7 MEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTE
. : ... :...: :. :.:. .:. . ::. ::. ... ..:..: :.:
NP_001 ADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTS
530 540 550 560 570 580
690 700 710 720 730 740
pF1KB7 TVIESDEFRPGIRYNFFLYGCRNQGYQ-LLRSMIGYIEELAPIVAPNFTVEDTSADSILV
::: .: ::::.::.: .:: .. ::.. :: .:::: :. :. .. :. .
NP_001 TVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTL
590 600 610 620 630 640
750 760 770 780 790
pF1KB7 KWEDIPVEELRGFLRGYLFYFGKGERDTS---KMRVLESGRSDIKVKNITDISQKTLRIA
.:.: .: ::..:: :. . :. . :: .: : : : . .:.: .
NP_001 SWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYK-IDNPEEKALIVD
650 660 670 680 690 700
800 810 820 830 840 850
pF1KB7 DLQGKTSYHLVLRAYTDGGVGPEKSMY-VVTKENSVGLIIAILIPVAVAVIVGVVTSILC
.:. .. :.. . .:..: :: .. :.: .. ...: ::.:.. :.. .: .:
NP_001 NLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLIMV---MC
710 720 730 740 750
860 870 880 890 900 910
pF1KB7 YRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEMNPCTPNNVEVLE----TR
: : .::::: :::::.: . . :.. : . . : .... : :. .::. :.
NP_001 YLKSQWIKETCYPDIPDPYKSSILSLIK--FKENPHLIIMNVSDCIPDAIEVVSKPEGTK
760 770 780 790 800 810
920 930 940 950 960
pF1KB7 SAF----PKIEDTEIISP--VAERPEDRSDAEPENHVVVSYCPPIIEEEIPNPAADEAGG
: .. .::. .: . : ... . : . : .:. : ::...:.
NP_001 IQFLGTRKSLTETELTKPNYLYLLPTEKNHSGPGPCI----C---FENLTYNQAASDSGS
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KB7 TAQV-IYIDVQSMYQPQAKPE---EEQENDPVGGAGYKPQMHLPINSTVEDIAAEEDLDK
..: . . :: ...:: . :.. ... : : . .:
NP_001 CGHVPVSPKAPSMLGLMTSPENVLKALEKNYMNSLGEIPAGETSLNYVSQLASPMFGDKD
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KB7 TAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKSNGGG
NP_001 SLPTNPVEAPHCSEYKMQMAVSLRLALPPPTENSSLSSITLLDPGEHYC
940 950 960 970
1097 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:35:24 2016 done: Sat Nov 5 08:35:26 2016
Total Scan time: 10.650 Total Display time: 0.430
Function used was FASTA [36.3.4 Apr, 2011]