Result of FASTA (omim) for
pF1KB7320
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7320, 1288 aa
1>>>pF1KB7320 1288 - 1288 aa - 1288 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6011+/-0.000582; mu= -3.9734+/- 0.036
mean_var=494.0522+/-100.199, 0's: 0 Z-trim(119.3): 162 B-trim: 119 in 2/56
Lambda= 0.057702
statistics sampled from 32997 (33175) to 32997 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.389), width: 16
Scan time: 15.410
The best scores are: opt bits E(85289)
NP_005487 (OMIM: 605575) structural maintenance of (1288) 8209 699.6 3.5e-200
NP_001002800 (OMIM: 605575) structural maintenance (1288) 8209 699.6 3.5e-200
XP_011510613 (OMIM: 605575) PREDICTED: structural (1288) 8209 699.6 3.5e-200
NP_001275682 (OMIM: 605575) structural maintenance (1263) 7723 659.2 5.2e-188
XP_011510614 (OMIM: 605575) PREDICTED: structural (1216) 7712 658.2 9.5e-188
XP_016860980 (OMIM: 605575) PREDICTED: structural ( 952) 5960 512.3 6.5e-144
XP_006713522 (OMIM: 605575) PREDICTED: structural (1210) 4763 412.7 7.5e-114
XP_011516455 (OMIM: 605576) PREDICTED: structural (1099) 611 67.1 7.8e-10
XP_011516454 (OMIM: 605576) PREDICTED: structural (1115) 611 67.1 7.9e-10
NP_001268392 (OMIM: 300040,300590) structural main (1211) 603 66.4 1.3e-09
NP_006297 (OMIM: 300040,300590) structural mainten (1233) 603 66.4 1.3e-09
NP_005436 (OMIM: 606062,610759) structural mainten (1217) 578 64.4 5.6e-09
XP_016869701 (OMIM: 605576) PREDICTED: structural (1147) 469 55.3 2.9e-06
XP_016869699 (OMIM: 605576) PREDICTED: structural (1147) 469 55.3 2.9e-06
XP_016869698 (OMIM: 605576) PREDICTED: structural (1147) 469 55.3 2.9e-06
XP_011516453 (OMIM: 605576) PREDICTED: structural (1147) 469 55.3 2.9e-06
XP_016869700 (OMIM: 605576) PREDICTED: structural (1147) 469 55.3 2.9e-06
XP_011516452 (OMIM: 605576) PREDICTED: structural (1147) 469 55.3 2.9e-06
NP_006435 (OMIM: 605576) structural maintenance of (1197) 469 55.3 3e-06
NP_001036015 (OMIM: 605576) structural maintenance (1197) 469 55.3 3e-06
XP_016869695 (OMIM: 605576) PREDICTED: structural (1197) 469 55.3 3e-06
XP_006716996 (OMIM: 605576) PREDICTED: structural (1197) 469 55.3 3e-06
XP_011516451 (OMIM: 605576) PREDICTED: structural (1197) 469 55.3 3e-06
XP_011516450 (OMIM: 605576) PREDICTED: structural (1197) 469 55.3 3e-06
XP_016869697 (OMIM: 605576) PREDICTED: structural (1197) 469 55.3 3e-06
NP_001252531 (OMIM: 605576) structural maintenance (1197) 469 55.3 3e-06
XP_016869696 (OMIM: 605576) PREDICTED: structural (1197) 469 55.3 3e-06
NP_001036016 (OMIM: 605576) structural maintenance (1197) 469 55.3 3e-06
XP_011528446 (OMIM: 608685) PREDICTED: structural (1194) 467 55.1 3.4e-06
NP_683515 (OMIM: 608685) structural maintenance of (1235) 467 55.1 3.4e-06
XP_011528447 (OMIM: 608685) PREDICTED: structural (1101) 434 52.3 2.1e-05
NP_001278430 (OMIM: 608685) structural maintenance (1161) 434 52.4 2.2e-05
NP_003793 (OMIM: 603487) myosin-13 [Homo sapiens] (1938) 340 44.8 0.0071
>>NP_005487 (OMIM: 605575) structural maintenance of chr (1288 aa)
initn: 8209 init1: 8209 opt: 8209 Z-score: 3715.0 bits: 699.6 E(85289): 3.5e-200
Smith-Waterman score: 8209; 100.0% identity (100.0% similar) in 1288 aa overlap (1-1288:1-1288)
10 20 30 40 50 60
pF1KB7 MPRKGTQPSTARRREEGPPPPSPDGASSDAEPEPPSGRTESPATAAETASEELDNRSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MPRKGTQPSTARRREEGPPPPSPDGASSDAEPEPPSGRTESPATAAETASEELDNRSLEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 ILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCIIGPNGSGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCIIGPNGSGKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 NVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEVIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEVIPN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 KGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 EKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIHEDTKEINEKSNILSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIHEDTKEINEKSNILSN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 DKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKES
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 REKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 REKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 IRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 DAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 QNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 LDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 SQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 ELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 AQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 ELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB7 IDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB7 ARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFY
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB7 IITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB7 LALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISD
1210 1220 1230 1240 1250 1260
1270 1280
pF1KB7 RLIGIYKTYNITKSVAVNPKEIASKGLC
::::::::::::::::::::::::::::
NP_005 RLIGIYKTYNITKSVAVNPKEIASKGLC
1270 1280
>>NP_001002800 (OMIM: 605575) structural maintenance of (1288 aa)
initn: 8209 init1: 8209 opt: 8209 Z-score: 3715.0 bits: 699.6 E(85289): 3.5e-200
Smith-Waterman score: 8209; 100.0% identity (100.0% similar) in 1288 aa overlap (1-1288:1-1288)
10 20 30 40 50 60
pF1KB7 MPRKGTQPSTARRREEGPPPPSPDGASSDAEPEPPSGRTESPATAAETASEELDNRSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRKGTQPSTARRREEGPPPPSPDGASSDAEPEPPSGRTESPATAAETASEELDNRSLEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 ILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCIIGPNGSGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCIIGPNGSGKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 NVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEVIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEVIPN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 KGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 EKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIHEDTKEINEKSNILSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIHEDTKEINEKSNILSN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 DKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKES
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 REKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 IRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 DAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 QNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 LDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 SQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 ELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 AQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 ELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB7 IDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB7 ARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFY
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB7 IITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB7 LALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISD
1210 1220 1230 1240 1250 1260
1270 1280
pF1KB7 RLIGIYKTYNITKSVAVNPKEIASKGLC
::::::::::::::::::::::::::::
NP_001 RLIGIYKTYNITKSVAVNPKEIASKGLC
1270 1280
>>XP_011510613 (OMIM: 605575) PREDICTED: structural main (1288 aa)
initn: 8209 init1: 8209 opt: 8209 Z-score: 3715.0 bits: 699.6 E(85289): 3.5e-200
Smith-Waterman score: 8209; 100.0% identity (100.0% similar) in 1288 aa overlap (1-1288:1-1288)
10 20 30 40 50 60
pF1KB7 MPRKGTQPSTARRREEGPPPPSPDGASSDAEPEPPSGRTESPATAAETASEELDNRSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPRKGTQPSTARRREEGPPPPSPDGASSDAEPEPPSGRTESPATAAETASEELDNRSLEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 ILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCIIGPNGSGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCIIGPNGSGKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 NVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEVIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEVIPN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 KGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 EKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIHEDTKEINEKSNILSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIHEDTKEINEKSNILSN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 DKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKES
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 REKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 IRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 DAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 QNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 LDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 SQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 ELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 AQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 ELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB7 IDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB7 ARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFY
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB7 IITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB7 LALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISD
1210 1220 1230 1240 1250 1260
1270 1280
pF1KB7 RLIGIYKTYNITKSVAVNPKEIASKGLC
::::::::::::::::::::::::::::
XP_011 RLIGIYKTYNITKSVAVNPKEIASKGLC
1270 1280
>>NP_001275682 (OMIM: 605575) structural maintenance of (1263 aa)
initn: 7723 init1: 7723 opt: 7723 Z-score: 3496.4 bits: 659.2 E(85289): 5.2e-188
Smith-Waterman score: 7980; 98.1% identity (98.1% similar) in 1288 aa overlap (1-1288:1-1263)
10 20 30 40 50 60
pF1KB7 MPRKGTQPSTARRREEGPPPPSPDGASSDAEPEPPSGRTESPATAAETASEELDNRSLEE
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRKGTQPSTARRREEGPPPPSPDGASSDAEPEPPSGRTESPATAA--------------
10 20 30 40
70 80 90 100 110 120
pF1KB7 ILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCIIGPNGSGKS
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----------AMTNEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCIIGPNGSGKS
50 60 70 80 90
130 140 150 160 170 180
pF1KB7 NVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEVIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEVIPN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 SNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKP
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 KGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 EKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIHEDTKEINEKSNILSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIHEDTKEINEKSNILSN
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB7 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQK
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB7 DKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKES
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB7 REKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAA
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB7 IRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVL
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB7 DAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKR
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB7 QNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADN
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB7 LDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKME
700 710 720 730 740 750
790 800 810 820 830 840
pF1KB7 SQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVK
760 770 780 790 800 810
850 860 870 880 890 900
pF1KB7 ELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLK
820 830 840 850 860 870
910 920 930 940 950 960
pF1KB7 AQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTA
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KB7 ELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQ
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KB7 IDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLE
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KB7 ARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFY
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KB7 IITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSS
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KB7 LALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISD
1180 1190 1200 1210 1220 1230
1270 1280
pF1KB7 RLIGIYKTYNITKSVAVNPKEIASKGLC
::::::::::::::::::::::::::::
NP_001 RLIGIYKTYNITKSVAVNPKEIASKGLC
1240 1250 1260
>>XP_011510614 (OMIM: 605575) PREDICTED: structural main (1216 aa)
initn: 7712 init1: 7712 opt: 7712 Z-score: 3491.7 bits: 658.2 E(85289): 9.5e-188
Smith-Waterman score: 7712; 100.0% identity (100.0% similar) in 1216 aa overlap (73-1288:1-1216)
50 60 70 80 90 100
pF1KB7 ATAAETASEELDNRSLEEILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKSYAGEKILG
::::::::::::::::::::::::::::::
XP_011 MTNEAGAPRLMITHIVNQNFKSYAGEKILG
10 20 30
110 120 130 140 150 160
pF1KB7 PFHKRFSCIIGPNGSGKSNVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFHKRFSCIIGPNGSGKSNVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEV
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB7 HFQKIIDKEGDDYEVIPNSNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFQKIIDKEGDDYEVIPNSNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDH
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB7 NRFLILQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRFLILQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRG
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB7 EKLNRVKMVEKEKDALEGEKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLNRVKMVEKEKDALEGEKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKE
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB7 KIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVRE
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB7 KLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKE
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB7 VMDSLKQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMDSLKQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTK
400 410 420 430 440 450
530 540 550 560 570 580
pF1KB7 AKEALIAASETLKERKAAIRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKEALIAASETLKERKAAIRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQK
460 470 480 490 500 510
590 600 610 620 630 640
pF1KB7 VEEAKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEEAKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDY
520 530 540 550 560 570
650 660 670 680 690 700
pF1KB7 IVVDSIDIAQECVNFLKRQNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVVDSIDIAQECVNFLKRQNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDE
580 590 600 610 620 630
710 720 730 740 750 760
pF1KB7 KIRQAFYFALRDTLVADNLDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIRQAFYFALRDTLVADNLDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGR
640 650 660 670 680 690
770 780 790 800 810 820
pF1KB7 MGSSLVIEISEEEVNKMESQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSSLVIEISEEEVNKMESQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFT
700 710 720 730 740 750
830 840 850 860 870 880
pF1KB7 ASIQRLIEQEEYLNVQVKELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASIQRLIEQEEYLNVQVKELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEA
760 770 780 790 800 810
890 900 910 920 930 940
pF1KB7 EVKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVL
820 830 840 850 860 870
950 960 970 980 990 1000
pF1KB7 RTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQE
880 890 900 910 920 930
1010 1020 1030 1040 1050 1060
pF1KB7 NEHALQKDALSIKLKLEQIDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEHALQKDALSIKLKLEQIDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPED
940 950 960 970 980 990
1070 1080 1090 1100 1110 1120
pF1KB7 LEAIKNPDSITNQIALLEARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEAIKNPDSITNQIALLEARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQ
1000 1010 1020 1030 1040 1050
1130 1140 1150 1160 1170 1180
pF1KB7 AYEDLRKQRLNEFMAGFYIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYEDLRKQRLNEFMAGFYIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPK
1060 1070 1080 1090 1100 1110
1190 1200 1210 1220 1230 1240
pF1KB7 KSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTK
1120 1130 1140 1150 1160 1170
1250 1260 1270 1280
pF1KB7 NAQFIIISLRNNMFEISDRLIGIYKTYNITKSVAVNPKEIASKGLC
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAQFIIISLRNNMFEISDRLIGIYKTYNITKSVAVNPKEIASKGLC
1180 1190 1200 1210
>>XP_016860980 (OMIM: 605575) PREDICTED: structural main (952 aa)
initn: 5960 init1: 5960 opt: 5960 Z-score: 2704.7 bits: 512.3 E(85289): 6.5e-144
Smith-Waterman score: 5960; 100.0% identity (100.0% similar) in 952 aa overlap (337-1288:1-952)
310 320 330 340 350 360
pF1KB7 EFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIHEDTKEINEKSNILSNEMKAKN
::::::::::::::::::::::::::::::
XP_016 METQKEKIHEDTKEINEKSNILSNEMKAKN
10 20 30
370 380 390 400 410 420
pF1KB7 KDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVE
40 50 60 70 80 90
430 440 450 460 470 480
pF1KB7 EFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREKELM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREKELM
100 110 120 130 140 150
490 500 510 520 530 540
pF1KB7 GFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAAIRDIEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAAIRDIEG
160 170 180 190 200 210
550 560 570 580 590 600
pF1KB7 KLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQE
220 230 240 250 260 270
610 620 630 640 650 660
pF1KB7 KKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKRQNIGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKRQNIGVA
280 290 300 310 320 330
670 680 690 700 710 720
pF1KB7 TFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADNLDQATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADNLDQATR
340 350 360 370 380 390
730 740 750 760 770 780
pF1KB7 VAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKMESQLQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKMESQLQND
400 410 420 430 440 450
790 800 810 820 830 840
pF1KB7 SKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVKELEANV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVKELEANV
460 470 480 490 500 510
850 860 870 880 890 900
pF1KB7 LATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLKAQQDKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLKAQQDKL
520 530 540 550 560 570
910 920 930 940 950 960
pF1KB7 DKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLE
580 590 600 610 620 630
970 980 990 1000 1010 1020
pF1KB7 DKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHIA
640 650 660 670 680 690
1030 1040 1050 1060 1070 1080
pF1KB7 EHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLEARCHEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLEARCHEM
700 710 720 730 740 750
1090 1100 1110 1120 1130 1140
pF1KB7 KPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFYIITNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFYIITNKL
760 770 780 790 800 810
1150 1160 1170 1180 1190 1200
pF1KB7 KENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFA
820 830 840 850 860 870
1210 1220 1230 1240 1250 1260
pF1KB7 LHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIY
880 890 900 910 920 930
1270 1280
pF1KB7 KTYNITKSVAVNPKEIASKGLC
::::::::::::::::::::::
XP_016 KTYNITKSVAVNPKEIASKGLC
940 950
>>XP_006713522 (OMIM: 605575) PREDICTED: structural main (1210 aa)
initn: 4639 init1: 4639 opt: 4763 Z-score: 2165.0 bits: 412.7 E(85289): 7.5e-114
Smith-Waterman score: 7576; 93.9% identity (93.9% similar) in 1288 aa overlap (1-1288:1-1210)
10 20 30 40 50 60
pF1KB7 MPRKGTQPSTARRREEGPPPPSPDGASSDAEPEPPSGRTESPATAAETASEELDNRSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPRKGTQPSTARRREEGPPPPSPDGASSDAEPEPPSGRTESPATAAETASEELDNRSLEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 ILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCIIGPNGSGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCIIGPNGSGKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 NVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEVIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEVIPN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 KGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 EKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIHEDTKEINEKSNILSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIHEDTKEINEKSNILSN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 DKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKES
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKE-
430 440 450 460 470
490 500 510 520 530 540
pF1KB7 REKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAA
XP_006 ------------------------------------------------------------
550 560 570 580 590 600
pF1KB7 IRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVL
:::::::::::::::::::::::::::::::::::::::::::
XP_006 -----------------KEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVL
480 490 500 510 520
610 620 630 640 650 660
pF1KB7 DAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKR
530 540 550 560 570 580
670 680 690 700 710 720
pF1KB7 QNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADN
590 600 610 620 630 640
730 740 750 760 770 780
pF1KB7 LDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKME
650 660 670 680 690 700
790 800 810 820 830 840
pF1KB7 SQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVK
710 720 730 740 750 760
850 860 870 880 890 900
pF1KB7 ELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLK
770 780 790 800 810 820
910 920 930 940 950 960
pF1KB7 AQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTA
830 840 850 860 870 880
970 980 990 1000 1010 1020
pF1KB7 ELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQ
890 900 910 920 930 940
1030 1040 1050 1060 1070 1080
pF1KB7 IDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLE
950 960 970 980 990 1000
1090 1100 1110 1120 1130 1140
pF1KB7 ARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFY
1010 1020 1030 1040 1050 1060
1150 1160 1170 1180 1190 1200
pF1KB7 IITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSS
1070 1080 1090 1100 1110 1120
1210 1220 1230 1240 1250 1260
pF1KB7 LALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISD
1130 1140 1150 1160 1170 1180
1270 1280
pF1KB7 RLIGIYKTYNITKSVAVNPKEIASKGLC
::::::::::::::::::::::::::::
XP_006 RLIGIYKTYNITKSVAVNPKEIASKGLC
1190 1200 1210
>>XP_011516455 (OMIM: 605576) PREDICTED: structural main (1099 aa)
initn: 347 init1: 132 opt: 611 Z-score: 297.5 bits: 67.1 E(85289): 7.8e-10
Smith-Waterman score: 722; 23.7% identity (58.0% similar) in 1172 aa overlap (82-1196:1-1090)
60 70 80 90 100 110
pF1KB7 ELDNRSLEEILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCI
. : :. ..::::: . .. : :. :
XP_011 MHIKSIILEGFKSYAQRTEVNGFDPLFNAI
10 20 30
120 130 140 150 160 170
pF1KB7 IGPNGSGKSNVIDSMLFVFGYRA-QKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDK
: :::::::..::. :..: ...:...:. :.... . : . .: . :.. :
XP_011 TGLNGSGKSNILDSICFLLGISNLSQVRASNLQDLVYKNGQ-AGITKASVSITFDNSDKK
40 50 60 70 80
180 190 200 210 220
pF1KB7 EGD-DYEVIPNSNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQ
.. .:: .... :.: . . . : :.: . . : .:. : :..... .:::.:
XP_011 QSPLGFEV--HDEITVTRQVVIGGRNKYLINGVNANNTRVQDLFCSVGLNVNNPHFLIMQ
90 100 110 120 130 140
230 240 250 260 270 280
pF1KB7 GEVEQIAMMKPKGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVK
:.. .. ::: .: ..:. : :. : :. ... :.. ::...:
XP_011 GRITKVLNMKPPE-------ILSMIEEAAGT-RMYEYKKIAAQKT---IEKKEAKLKEIK
150 160 170 180 190
290 300 310 320 330 340
pF1KB7 MVEKEK-----DALEGEKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKI
. .:. . :. :.. .:. ....:. .:. . :: : .:: : .
XP_011 TILEEEITPTIQKLKEERSSYLEY----QKVMREIEHLSRLYI-AYQFLLAE--DTKVRS
200 210 220 230 240
350 360 370 380 390
pF1KB7 HEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQL-DLEDV-----
:. ::...: :..:.. ..: .: ....... : ...:: : .:::.
XP_011 AEELKEMQDKVIKLQEELSENDKKIKALNHEIEELEK--RKDKETGGILRSLEDALAEAQ
250 260 270 280 290 300
400 410 420 430 440 450
pF1KB7 QVREKLKHATSKAKK---LEKQLQKDKEK--VEEFKSIPAKSNNIINETTTRNNALEKEK
.: : . : . :: :.. .:. :: ::. :.. :: ... .. : .::.. .
XP_011 RVNTKSQSAFDLKKKNLACEESKRKELEKNMVEDSKTLAAKEKEV-KKITDGLHALQEAS
310 320 330 340 350 360
460 470 480 490 500 510
pF1KB7 EKEEKKLKEVMDSLKQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSELDIYLSRH
.:. . : ... .. . ::...... : : : .. .. .. ::.:
XP_011 NKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAG---QMMACKNDISKAQTEA-------
370 380 390 400 410
520 530 540 550 560 570
pF1KB7 NTAVSQLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQELKEK-EKELQKLTQEETNF
. : .: .:.. : . .:. .. : . : .. ..:::: : :..::. ::..
XP_011 KQAQMKLKHAQQELKNKQAEVKKMDSGYRKDQEAL-EAVKRLKEKLEAEMKKLNYEENKE
420 430 440 450 460 470
580 590 600 610 620
pF1KB7 KSLVH---DLFQKVEEAKSSLAMNRSRGKVLDAIIQ--EKKSGR--IPGIYGRLGDLGAI
.::.. .: . . . : . .: : . ::. .: . :. . : ...
XP_011 ESLLEKRRQLSRDIGRLKETYEALLARFPNLRFAYKDPEKNWNRNCVKGLVASL--ISVK
480 490 500 510 520 530
630 640 650 660 670 680
pF1KB7 DEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKRQNIGVA-TFIGLDKMA---VWAKKM
: . .:. : :: . ... . ..:.: .. :.: :.:.. . . .
XP_011 DTSATTALELVAGERLYNVVVDTEVTGK--KLLERGELKRRYTIIPLNKISARCIAPETL
540 550 560 570 580 590
690 700 710 720 730
pF1KB7 TEIQT---PENTPRLFDLVKVKDEKIRQAFYFALRDTLVADNLDQATRVAYQKDRRWRVV
:. :.:. ..::. : : ...:. :.. :.: ::.:.: .::..: :.:
XP_011 RVAQNLVGPDNVHVALSLVEYKPE-LQKAMEFVFGTTFVCDNMDNAKKVAFDKRIMTRTV
600 610 620 630 640 650
740 750 760 770 780 790
pF1KB7 TLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKMESQLQNDSKKAMQIQEQKV
:: :.... ::..::. . ...:.. ...: . : . ..:.:...
XP_011 TLGGDVFDPHGTLSGGARS-----QAASILTKFQELK----------DVQDELRIKENEL
660 670 680 690
800 810 820 830 840 850
pF1KB7 Q-LEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVKELEANVLATAPDKKKQK
. :::... :. :: ::. : ..:. ..: ::..: : .... .
XP_011 RALEEELAGLK-------NTAEKY-----RQLKQQW----EMKTEEADLLQTKLQQSSYH
700 710 720 730
860 870 880 890 900 910
pF1KB7 LLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLK---AQQDK-LDKINKQL
.:...:.: . .:.. : :..: . :. ..:.: :.... : .:.:
XP_011 KQQEELDALKKTIEE-SEETLKNTKEIQRKAEEKYEVLENKMKNAEAERERELKDAQKKL
740 750 760 770 780 790
920 930 940 950 960
pF1KB7 DECASAITKAQVAIKTADRNLQKAQDSVLRTE---KEIKDTEKEVDDLTAELKSLEDK--
: ::. :::... : .. :... .:. : .: . ..... .. .:: :..
XP_011 D-CAK--TKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVNEAIKSYESQIE
800 810 820 830 840 850
970 980 990 1000 1010 1020
pF1KB7 --AAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQEN--EHALQKDALS-IKLKLEQIDG
::::.:: ...... :. :... . . ::. . : : .:. . .::....:
XP_011 VMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNNDSQLKIKELDH
860 870 880 890 900 910
1030 1040 1050 1060 1070 1080
pF1KB7 HIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIK--NPDSITNQIALLEA
.:..:. . . ..::. :. . :. .:.. .: :: ... :.
XP_011 NISKHKREAEDGAAKVSKM-LKDYDWINAERHLFGQPNSAYDFKTNNPKEAGQRLQKLQ-
920 930 940 950 960 970
1090 1100 1110 1120 1130
pF1KB7 RCHEMKPNLG------AIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEF
::: .:: :. . :: : . . . . ..... . ::: ... . .
XP_011 ---EMKEKLGRNVNMRAMNVLTEAEERYNDLMKKKRIVENDKSKILTTIEDLDQKKNQAL
980 990 1000 1010 1020 1030
1140 1150 1160 1170 1180 1190
pF1KB7 MAGFYIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKK-IFNLSGG
.. ... . .. : :..: : .. . .:. :.: ..::. . .::::
XP_011 NIAWQKVNKDFGSIFSTLLPGANAMLAPPEG-QTVLDGLEFKV-ALGNTWKENLTELSGG
1040 1050 1060 1070 1080
1200 1210 1220 1230 1240 1250
pF1KB7 EKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNN
..
XP_011 QRQKQQNHTTG
1090
>>XP_011516454 (OMIM: 605576) PREDICTED: structural main (1115 aa)
initn: 347 init1: 132 opt: 611 Z-score: 297.4 bits: 67.1 E(85289): 7.9e-10
Smith-Waterman score: 722; 23.7% identity (58.0% similar) in 1172 aa overlap (82-1196:1-1090)
60 70 80 90 100 110
pF1KB7 ELDNRSLEEILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCI
. : :. ..::::: . .. : :. :
XP_011 MHIKSIILEGFKSYAQRTEVNGFDPLFNAI
10 20 30
120 130 140 150 160 170
pF1KB7 IGPNGSGKSNVIDSMLFVFGYRA-QKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDK
: :::::::..::. :..: ...:...:. :.... . : . .: . :.. :
XP_011 TGLNGSGKSNILDSICFLLGISNLSQVRASNLQDLVYKNGQ-AGITKASVSITFDNSDKK
40 50 60 70 80
180 190 200 210 220
pF1KB7 EGD-DYEVIPNSNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQ
.. .:: .... :.: . . . : :.: . . : .:. : :..... .:::.:
XP_011 QSPLGFEV--HDEITVTRQVVIGGRNKYLINGVNANNTRVQDLFCSVGLNVNNPHFLIMQ
90 100 110 120 130 140
230 240 250 260 270 280
pF1KB7 GEVEQIAMMKPKGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVK
:.. .. ::: .: ..:. : :. : :. ... :.. ::...:
XP_011 GRITKVLNMKPPE-------ILSMIEEAAGT-RMYEYKKIAAQKT---IEKKEAKLKEIK
150 160 170 180 190
290 300 310 320 330 340
pF1KB7 MVEKEK-----DALEGEKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKI
. .:. . :. :.. .:. ....:. .:. . :: : .:: : .
XP_011 TILEEEITPTIQKLKEERSSYLEY----QKVMREIEHLSRLYI-AYQFLLAE--DTKVRS
200 210 220 230 240
350 360 370 380 390
pF1KB7 HEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQL-DLEDV-----
:. ::...: :..:.. ..: .: ....... : ...:: : .:::.
XP_011 AEELKEMQDKVIKLQEELSENDKKIKALNHEIEELEK--RKDKETGGILRSLEDALAEAQ
250 260 270 280 290 300
400 410 420 430 440 450
pF1KB7 QVREKLKHATSKAKK---LEKQLQKDKEK--VEEFKSIPAKSNNIINETTTRNNALEKEK
.: : . : . :: :.. .:. :: ::. :.. :: ... .. : .::.. .
XP_011 RVNTKSQSAFDLKKKNLACEESKRKELEKNMVEDSKTLAAKEKEV-KKITDGLHALQEAS
310 320 330 340 350 360
460 470 480 490 500 510
pF1KB7 EKEEKKLKEVMDSLKQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSELDIYLSRH
.:. . : ... .. . ::...... : : : .. .. .. ::.:
XP_011 NKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAG---QMMACKNDISKAQTEA-------
370 380 390 400 410
520 530 540 550 560 570
pF1KB7 NTAVSQLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQELKEK-EKELQKLTQEETNF
. : .: .:.. : . .:. .. : . : .. ..:::: : :..::. ::..
XP_011 KQAQMKLKHAQQELKNKQAEVKKMDSGYRKDQEAL-EAVKRLKEKLEAEMKKLNYEENKE
420 430 440 450 460 470
580 590 600 610 620
pF1KB7 KSLVH---DLFQKVEEAKSSLAMNRSRGKVLDAIIQ--EKKSGR--IPGIYGRLGDLGAI
.::.. .: . . . : . .: : . ::. .: . :. . : ...
XP_011 ESLLEKRRQLSRDIGRLKETYEALLARFPNLRFAYKDPEKNWNRNCVKGLVASL--ISVK
480 490 500 510 520 530
630 640 650 660 670 680
pF1KB7 DEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKRQNIGVA-TFIGLDKMA---VWAKKM
: . .:. : :: . ... . ..:.: .. :.: :.:.. . . .
XP_011 DTSATTALELVAGERLYNVVVDTEVTGK--KLLERGELKRRYTIIPLNKISARCIAPETL
540 550 560 570 580 590
690 700 710 720 730
pF1KB7 TEIQT---PENTPRLFDLVKVKDEKIRQAFYFALRDTLVADNLDQATRVAYQKDRRWRVV
:. :.:. ..::. : : ...:. :.. :.: ::.:.: .::..: :.:
XP_011 RVAQNLVGPDNVHVALSLVEYKPE-LQKAMEFVFGTTFVCDNMDNAKKVAFDKRIMTRTV
600 610 620 630 640 650
740 750 760 770 780 790
pF1KB7 TLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKMESQLQNDSKKAMQIQEQKV
:: :.... ::..::. . ...:.. ...: . : . ..:.:...
XP_011 TLGGDVFDPHGTLSGGARS-----QAASILTKFQELK----------DVQDELRIKENEL
660 670 680 690
800 810 820 830 840 850
pF1KB7 Q-LEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVKELEANVLATAPDKKKQK
. :::... :. :: ::. : ..:. ..: ::..: : .... .
XP_011 RALEEELAGLK-------NTAEKY-----RQLKQQW----EMKTEEADLLQTKLQQSSYH
700 710 720 730
860 870 880 890 900 910
pF1KB7 LLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLK---AQQDK-LDKINKQL
.:...:.: . .:.. : :..: . :. ..:.: :.... : .:.:
XP_011 KQQEELDALKKTIEE-SEETLKNTKEIQRKAEEKYEVLENKMKNAEAERERELKDAQKKL
740 750 760 770 780 790
920 930 940 950 960
pF1KB7 DECASAITKAQVAIKTADRNLQKAQDSVLRTE---KEIKDTEKEVDDLTAELKSLEDK--
: ::. :::... : .. :... .:. : .: . ..... .. .:: :..
XP_011 D-CAK--TKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVNEAIKSYESQIE
800 810 820 830 840 850
970 980 990 1000 1010 1020
pF1KB7 --AAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQEN--EHALQKDALS-IKLKLEQIDG
::::.:: ...... :. :... . . ::. . : : .:. . .::....:
XP_011 VMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNNDSQLKIKELDH
860 870 880 890 900 910
1030 1040 1050 1060 1070 1080
pF1KB7 HIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIK--NPDSITNQIALLEA
.:..:. . . ..::. :. . :. .:.. .: :: ... :.
XP_011 NISKHKREAEDGAAKVSKM-LKDYDWINAERHLFGQPNSAYDFKTNNPKEAGQRLQKLQ-
920 930 940 950 960 970
1090 1100 1110 1120 1130
pF1KB7 RCHEMKPNLG------AIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEF
::: .:: :. . :: : . . . . ..... . ::: ... . .
XP_011 ---EMKEKLGRNVNMRAMNVLTEAEERYNDLMKKKRIVENDKSKILTTIEDLDQKKNQAL
980 990 1000 1010 1020 1030
1140 1150 1160 1170 1180 1190
pF1KB7 MAGFYIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKK-IFNLSGG
.. ... . .. : :..: : .. . .:. :.: ..::. . .::::
XP_011 NIAWQKVNKDFGSIFSTLLPGANAMLAPPEG-QTVLDGLEFKV-ALGNTWKENLTELSGG
1040 1050 1060 1070 1080
1200 1210 1220 1230 1240 1250
pF1KB7 EKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNN
..
XP_011 QRQYEYFSDKNSRTILQVKGSSQAKGK
1090 1100 1110
>>NP_001268392 (OMIM: 300040,300590) structural maintena (1211 aa)
initn: 469 init1: 243 opt: 603 Z-score: 293.4 bits: 66.4 E(85289): 1.3e-09
Smith-Waterman score: 1120; 25.5% identity (58.1% similar) in 1268 aa overlap (118-1279:15-1206)
90 100 110 120 130 140
pF1KB7 VNQNFKSYAGEKILGPFHKRFSCIIGPNGSGKSNVIDSMLFVFGYRAQKIRSKKLSVLIH
::::..:.. ::.: .....: : : :::
NP_001 MLEVSIPTPHRYVRGKSNLMDAISFVLGEKTSNLRVKTLRDLIH
10 20 30 40
150 160 170 180 190 200
pF1KB7 NSDEHKDIQSCTVEVHFQKIIDKEGDDYEVIPNSNFYVSRTACRDNTSVYHISGKKKTFK
.. : . .. . . ..:: . . .: .:. ..: :.:..: ..
NP_001 GAPVGKPAAN---RAFVSMVYSEEGAE-----DRTF--ARVIV-GGSSEYKINNKVVQLH
50 60 70 80 90
210 220 230 240 250 260
pF1KB7 DVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGCGRLNEPI
. .. :.. :: . ::..:: ::.::: .:: .: .:.: :.: .
NP_001 EYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERTA-------LFEEISRSGELAQEY
100 110 120 130 140
270 280 290 300 310 320
pF1KB7 KVLCRRVEILNEHRGEKLN--RVKMVEKEKDALEGEKNIAIEFLTLENEIFRKKNHVCQY
:. :... .. ..: : : . :. . ::. : .. :..:. : . .. .
NP_001 DK--RKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLF
150 160 170 180 190 200
330 340 350 360 370 380
pF1KB7 YIY----ELQKRIAEMETQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITK
.: :..: :. .....:..: :.... . .:.: :.:.. .. ..: :
NP_001 KLYHNEVEIEKLNKELASKNKEIEKDKKRMDK----VEDELKEKKKELGKMMREQQQIEK
210 220 230 240 250 260
390 400 410 420 430 440
pF1KB7 FIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINE
:.:. ...: . ....:. .: .: . .:.::. ... .: : .. ..:
NP_001 EIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKH---YK----KRKGDMDE
270 280 290 300 310
450 460 470 480 490 500
pF1KB7 TTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREKELMGFSKSVNEARSKMDV
:::: . :: .: . ...:.:. .. .:... . . .:: .. .
NP_001 -------LEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAAT
320 330 340 350 360
510 520 530 540 550 560
pF1KB7 AQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQELKEKEKE
.::. . .: . : .. : :.::: . . :.:. : .:..:..:.
NP_001 LAQELEKF-NRDQKA------DQDRL-----DLEERKKV--ETEAKIKQKLREIEENQKR
370 380 390 400 410
570 580 590 600
pF1KB7 LQKLTQEETNFKS-------LVHDLFQKVEEAKSSL-AMNRSRGKVL----DAIIQEKKS
..:: . :. :. : .: ..:: :: . .:. ..:. :: :....:
NP_001 IEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQES
420 430 440 450 460 470
610 620 630 640 650
pF1KB7 GR--------------IPG-IYGRLGDL-GAIDEKYDVAISSCC-HALDYIVVDSIDIAQ
.: :: .:::: :: ..::..:... . .: :.::: ..
NP_001 SRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGR
480 490 500 510 520 530
660 670 680 690 700 710
pF1KB7 ECVNFLKRQNIGVATFIGLDKMAVWA--KKMTEIQTPENTPRLFDLVKVKDEKIRQAFYF
.:....:.: ::. :: . : .:. :.. .. ..:... . .:..:. .
NP_001 DCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK---GAKLVIDVIRYEPPHIKKALQY
540 550 560 570 580
720 730 740 750 760
pF1KB7 ALRDTLVADNLDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGS--KVMKGRMGSSLV
: ..:: ::...: :.:. .: ..:.:.: ....::...::.: :. : . :
NP_001 ACGNALVCDNVEDARRIAFGGHQRHKTVALDGTLFQKSGVISGGASDLKAKARRWDEKAV
590 600 610 620 630 640
770 780 790 800 810 820
pF1KB7 IEISEEE---VNKMESQLQNDSKKAM--QIQEQKVQLEERVVKLRHSEREMRNTLEKFTA
...:.. ..... :.. :.: :.: : :. : :..:. ....: . :
NP_001 DKLKEKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMR---LKYSQSDLEQTKTRHLA
650 660 670 680 690 700
830 840 850 860 870 880
pF1KB7 SIQRLIEQEEYLNVQVK-ELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEA
::.: : .::... .: . . ... ... . :. . :: ..::
NP_001 -----------LNLQEKSKLESELANFGP---RINDIKRIIQSREREMKDLKEKMNQVED
710 720 730 740 750
890 900 910 920 930
pF1KB7 EVKRLHNTIVEINNHKLKAQQDKL---DKINKQLDECASAITKAQVAIKTADRNLQKAQD
:: . . . : . . ...:. ..: :. : . :. . . .:.. ::
NP_001 EVFEEFCREIGVRNIR-EFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQD
760 770 780 790 800 810
940 950 960 970 980 990
pF1KB7 SVLRTEKEIKDTEKEVDDLTAE----LKSLEDKAAEV--VKNTNAAEES-LPEIQKEHRN
.: :. .: :.:.. : : .: ... :.. .:: . :..: . . ..: ..
NP_001 KVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEE
820 830 840 850 860 870
1000 1010 1020 1030 1040 1050
pF1KB7 LLQELKVIQENEHALQKDALSIKLKLEQI--DGHIAEHNSKIKYWHKEISKISLHPIEDN
. ..: ... :::.. .:. :::: : : . :.. . .:: .. .:
NP_001 IRKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTM---DDI
880 890 900 910 920
1060 1070 1080 1090
pF1KB7 PIEEISVLSPEDLEAIKNPDSITNQIALLEAR----CH---------EMKPNLGAIAEYK
:: : . ... . . .:: . ::.: :. :.: ..... .
NP_001 SQEEGSSQGEDSVSGSQRISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKL
930 940 950 960 970 980
1100 1110 1120 1130
pF1KB7 KKEELYLQRVAE-----LDKITYERDSF-----------------RQAYEDLRKQRLNEF
.... :::.: ..:. ::.: .::.:...:.:...:
NP_001 NEQQSVLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRF
990 1000 1010 1020 1030 1040
1140 1150 1160 1170 1180 1190
pF1KB7 MAGFYIITNKLKENYQMLTLGGDAELEL--VDSLDPFSEGIMFSVRPPKKSWKKIFNLSG
: : ..... : :. :. ...:. : . .:. .:: .. : : .. . ::::
NP_001 NACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSG
1050 1060 1070 1080 1090 1100
1200 1210 1220 1230 1240 1250
pF1KB7 GEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQ-TKNAQFIIISLR
::::...:::.::.: :::.:.. .:::::::: :.. :: :: :: : : : :.:::.
NP_001 GEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKEQSTCNFQAIVISLK
1110 1120 1130 1140 1150 1160
1260 1270 1280
pF1KB7 NNMFEISDRLIGIYK-----------TYNITKSVAVNPKEIASKGLC
.... .. :::.: :...:: .::
NP_001 EEFYTKAESLIGVYPEQGDCVISKVLTFDLTKYPDANPNPNEQ
1170 1180 1190 1200 1210
1288 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:38:32 2016 done: Sat Nov 5 08:38:34 2016
Total Scan time: 15.410 Total Display time: 0.590
Function used was FASTA [36.3.4 Apr, 2011]