FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7324, 1279 aa 1>>>pF1KB7324 1279 - 1279 aa - 1279 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9069+/-0.000824; mu= 17.3951+/- 0.050 mean_var=141.9385+/-28.496, 0's: 0 Z-trim(113.2): 29 B-trim: 147 in 1/51 Lambda= 0.107653 statistics sampled from 13788 (13817) to 13788 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.424), width: 16 Scan time: 5.870 The best scores are: opt bits E(32554) CCDS41580.1 ADGRA1 gene_id:84435|Hs108|chr10 ( 560) 3956 626.4 6.2e-179 CCDS76362.1 ADGRA1 gene_id:84435|Hs108|chr10 ( 463) 3324 528.2 1.9e-149 CCDS33964.1 ADGRA3 gene_id:166647|Hs108|chr4 (1321) 1232 203.7 2.7e-51 CCDS6097.2 ADGRA2 gene_id:25960|Hs108|chr8 (1338) 781 133.6 3.3e-30 >>CCDS41580.1 ADGRA1 gene_id:84435|Hs108|chr10 (560 aa) initn: 2866 init1: 2866 opt: 3956 Z-score: 3325.9 bits: 626.4 E(32554): 6.2e-179 Smith-Waterman score: 3956; 99.8% identity (99.8% similar) in 559 aa overlap (722-1279:2-560) 700 710 720 730 740 750 pF1KB7 GLVLAGRTRSVASGGKQELSGPLAACIPTQDLKTVLSLPRYPGEFLHPVVYACTAVMLLC :::::::::::::::::::::::::::::: CCDS41 MDLKTVLSLPRYPGEFLHPVVYACTAVMLLC 10 20 30 760 770 780 790 800 810 pF1KB7 LLASFVTYIVHQSAIRISRKGRHTLLNFCFHAALTFTVFAGGINRTKYPILCQAVGIVLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LLASFVTYIVHQSAIRISRKGRHTLLNFCFHAALTFTVFAGGINRTKYPILCQAVGIVLH 40 50 60 70 80 90 820 830 840 850 860 870 pF1KB7 YSTLSTMLWIGVTARNIYKQVTKKAPLCLDTDQPPYPRQPLLRFYLVSGGVPFIICGVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 YSTLSTMLWIGVTARNIYKQVTKKAPLCLDTDQPPYPRQPLLRFYLVSGGVPFIICGVTA 100 110 120 130 140 150 880 890 900 910 920 930 pF1KB7 ATNIRNYGTEDEDTA-CWMAWEPSLGAFYGPAAIITLVTCVYFLGTYVQLRRHPGRRYEL ::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: CCDS41 ATNIRNYGTEDEDTAYCWMAWEPSLGAFYGPAAIITLVTCVYFLGTYVQLRRHPGRRYEL 160 170 180 190 200 210 940 950 960 970 980 990 pF1KB7 RTQPEEQRRLATPEGGRGIRPGTPPAHDAPGASVLQNEHSFQAQLRAAAFTLFLFTATWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 RTQPEEQRRLATPEGGRGIRPGTPPAHDAPGASVLQNEHSFQAQLRAAAFTLFLFTATWA 220 230 240 250 260 270 1000 1010 1020 1030 1040 1050 pF1KB7 FGALAVSQGHFLDMVFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWACCPPRKDAHPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 FGALAVSQGHFLDMVFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWACCPPRKDAHPAL 280 290 300 310 320 330 1060 1070 1080 1090 1100 1110 pF1KB7 DANGAALGRAACLHSPGLGQPRGFAHPPGPCKMTNLQAAQGHASCLSPATPCCAKMHCEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DANGAALGRAACLHSPGLGQPRGFAHPPGPCKMTNLQAAQGHASCLSPATPCCAKMHCEP 340 350 360 370 380 390 1120 1130 1140 1150 1160 1170 pF1KB7 LTADEAHVHLQEEGAFGHDPHLHGCLQGRTKPPYFSRHPAEEPEYAYHIPSSLDGSPRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LTADEAHVHLQEEGAFGHDPHLHGCLQGRTKPPYFSRHPAEEPEYAYHIPSSLDGSPRSS 400 410 420 430 440 450 1180 1190 1200 1210 1220 1230 pF1KB7 RTDSPPSSLDGPAGTHTLACCTQGDPFPMVTQPEGSDGSPALYSCPTQPGREAALGPGHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 RTDSPPSSLDGPAGTHTLACCTQGDPFPMVTQPEGSDGSPALYSCPTQPGREAALGPGHL 460 470 480 490 500 510 1240 1250 1260 1270 pF1KB7 EMLRRTQSLPFGGPSQNGLPKGKLLEGLPFGTDGTGNIRTGPWKNETTV ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EMLRRTQSLPFGGPSQNGLPKGKLLEGLPFGTDGTGNIRTGPWKNETTV 520 530 540 550 560 >>CCDS76362.1 ADGRA1 gene_id:84435|Hs108|chr10 (463 aa) initn: 2866 init1: 2866 opt: 3324 Z-score: 2796.5 bits: 528.2 E(32554): 1.9e-149 Smith-Waterman score: 3324; 99.8% identity (99.8% similar) in 463 aa overlap (818-1279:1-463) 790 800 810 820 830 840 pF1KB7 TVFAGGINRTKYPILCQAVGIVLHYSTLSTMLWIGVTARNIYKQVTKKAPLCLDTDQPPY :::::::::::::::::::::::::::::: CCDS76 MLWIGVTARNIYKQVTKKAPLCLDTDQPPY 10 20 30 850 860 870 880 890 900 pF1KB7 PRQPLLRFYLVSGGVPFIICGVTAATNIRNYGTEDEDTA-CWMAWEPSLGAFYGPAAIIT ::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::: CCDS76 PRQPLLRFYLVSGGVPFIICGVTAATNIRNYGTEDEDTAYCWMAWEPSLGAFYGPAAIIT 40 50 60 70 80 90 910 920 930 940 950 960 pF1KB7 LVTCVYFLGTYVQLRRHPGRRYELRTQPEEQRRLATPEGGRGIRPGTPPAHDAPGASVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 LVTCVYFLGTYVQLRRHPGRRYELRTQPEEQRRLATPEGGRGIRPGTPPAHDAPGASVLQ 100 110 120 130 140 150 970 980 990 1000 1010 1020 pF1KB7 NEHSFQAQLRAAAFTLFLFTATWAFGALAVSQGHFLDMVFSCLYGAFCVTLGLFVLIHHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 NEHSFQAQLRAAAFTLFLFTATWAFGALAVSQGHFLDMVFSCLYGAFCVTLGLFVLIHHC 160 170 180 190 200 210 1030 1040 1050 1060 1070 1080 pF1KB7 AKREDVWQCWWACCPPRKDAHPALDANGAALGRAACLHSPGLGQPRGFAHPPGPCKMTNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 AKREDVWQCWWACCPPRKDAHPALDANGAALGRAACLHSPGLGQPRGFAHPPGPCKMTNL 220 230 240 250 260 270 1090 1100 1110 1120 1130 1140 pF1KB7 QAAQGHASCLSPATPCCAKMHCEPLTADEAHVHLQEEGAFGHDPHLHGCLQGRTKPPYFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 QAAQGHASCLSPATPCCAKMHCEPLTADEAHVHLQEEGAFGHDPHLHGCLQGRTKPPYFS 280 290 300 310 320 330 1150 1160 1170 1180 1190 1200 pF1KB7 RHPAEEPEYAYHIPSSLDGSPRSSRTDSPPSSLDGPAGTHTLACCTQGDPFPMVTQPEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 RHPAEEPEYAYHIPSSLDGSPRSSRTDSPPSSLDGPAGTHTLACCTQGDPFPMVTQPEGS 340 350 360 370 380 390 1210 1220 1230 1240 1250 1260 pF1KB7 DGSPALYSCPTQPGREAALGPGHLEMLRRTQSLPFGGPSQNGLPKGKLLEGLPFGTDGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 DGSPALYSCPTQPGREAALGPGHLEMLRRTQSLPFGGPSQNGLPKGKLLEGLPFGTDGTG 400 410 420 430 440 450 1270 pF1KB7 NIRTGPWKNETTV ::::::::::::: CCDS76 NIRTGPWKNETTV 460 >>CCDS33964.1 ADGRA3 gene_id:166647|Hs108|chr4 (1321 aa) initn: 1424 init1: 964 opt: 1232 Z-score: 1034.5 bits: 203.7 E(32554): 2.7e-51 Smith-Waterman score: 1433; 43.3% identity (67.1% similar) in 571 aa overlap (736-1279:758-1321) 710 720 730 740 750 760 pF1KB7 GKQELSGPLAACIPTQDLKTVLSLPRYPGEFLHPVVYACTAVMLLCLLASFVTYIVHQSA .::::::. . ..:::::: .:.:: :.: CCDS33 NITTIQCYSLSNYAVLMDLTGSELYTQAASLLHPVVYTTAIILLLCLLAVIVSYIYHHSL 730 740 750 760 770 780 770 780 790 800 810 820 pF1KB7 IRISRKGRHTLLNFCFHAALTFTVFAGGINRTKYPILCQAVGIVLHYSTLSTMLWIGVTA :::: :. : :.:.::: :: .::.:::..:. .::::::.::::::.:.::.:::: CCDS33 IRISLKSWHMLVNLCFHIFLTCVVFVGGITQTRNASICQAVGIILHYSTLATVLWVGVTA 790 800 810 820 830 840 830 840 850 860 870 880 pF1KB7 RNIYKQVTKKAPLCLDTDQPPYPRQPLLRFYLVSGGVPFIICGVTAATNIRNYGTEDEDT ::::::::::: : : :.:: : .:.:::::..::.:.:.::.:::.::.:::.. . CCDS33 RNIYKQVTKKAKRCQDPDEPPPPPRPMLRFYLIGGGIPIIVCGITAAANIKNYGSRPNAP 850 860 870 880 890 900 890 900 910 920 930 940 pF1KB7 ACWMAWEPSLGAFYGPAAIITLVTCVYFLGTYVQLRRHPGRRYELRTQPEEQRRLATPEG ::::::::::::::::..::.:.:.:::. ..::.::: :.:::. :::.:::. :. CCDS33 YCWMAWEPSLGAFYGPASFITFVNCMYFLSIFIQLKRHPERKYELKEPTEEQQRLAANEN 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KB7 GRGIRPGTPPAHDAPGASVLQNEHSFQAQLRAAAFTLFLFTATWAFGALAVSQGHFLDMV :. : . . ..:.:.:::.:..:: .:..::.:..: : ::::::: . ::.: CCDS33 GE-INHQDSMSLSLISTSALENEHTFHSQLLGASLTLLLYVALWMFGALAVSLYYPLDLV 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 pF1KB7 FSCLYGAFCVTLGLFVLIHHCAKREDVWQCW-WACCPPRK------DAHPALDANGAALG :: ..:: .... : ..:::..:::: : .::: :. ...: ..::. CCDS33 FSFVFGATSLSFSAFFVVHHCVNREDVRLAWIMTCCPGRSSYSVQVNVQPP-NSNGTNGE 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KB7 RAACLHSPGLGQ-----PRGFAHPPGPCKMTNLQAA--QGHASCLS-PATPCCAKMHCEP : .: . .. .: . ::.:::::: : ::. : .:: . : CCDS33 APKCPNSSAESSCTNKSASSFKNSSQGCKLTNLQAAAAQCHANSLPLNSTPQLDNSLTEH 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 pF1KB7 LTADEAHVHLQE-EGAFGHDPHLHGCLQGRTKPPYFSRHPAEEPEYAYHIPSSLDGSPRS .. ..:. : : . : ..:.: :: . . :::: .:.:..:: .. CCDS33 SMDNDIKMHVAPLEVQFRTNVHSSRHHKNRSKGHRASRLTVLR-EYAYDVPTSVEGSVQN 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 pF1KB7 SRTDSPPSSLDGPAGTHTLACCTQGDPFPMVTQPEGSDGSPALYSCP-----------TQ . : : : . : :. . . .: .:.: : . : : CCDS33 GL---PKSRLGNNEG-HSRSRRAYLAYRERQYNPPQQDSSDACSTLPKSSRNFEKPVSTT 1210 1220 1230 1240 1250 1260 1220 1230 1240 1250 1260 1270 pF1KB7 PGREAALGPGHLEMLRRTQSLPFGGPSQNGLPKGKLLEGLPFGTDGTGNIRTGPWKNETT ..: :. .:. . .: .. ::: :.. :: .:::.:::.::: ::.::: CCDS33 SKKDALRKPAVVELENQQKSYGLNLAIQNGPIKSNGQEGPLLGTDSTGNVRTGLWKHETT 1270 1280 1290 1300 1310 1320 pF1KB7 V : CCDS33 V >>CCDS6097.2 ADGRA2 gene_id:25960|Hs108|chr8 (1338 aa) initn: 1121 init1: 604 opt: 781 Z-score: 655.9 bits: 133.6 E(32554): 3.3e-30 Smith-Waterman score: 1223; 39.5% identity (60.6% similar) in 696 aa overlap (637-1279:681-1338) 610 620 630 640 650 660 pF1KB7 TPHCVGKKVPQPVGAADLAPDTSLCRKEGSSASRSCRPGPGHLTRREEDSFRQLAFPRFE ... .: : :.::. :.:. : : CCDS60 GRLFHSHSNTSRPGAAGPGKRRGVATPVIFAGTSGC--GVGNLTEPVAVSLRHWA----E 660 670 680 690 700 670 680 690 700 710 720 pF1KB7 EVTFPPLTA--AERAPSVHGGHSLASQGLVLAGRTRSVASGGKQELSGPLAACIPTQDLK . :..: ....:. :: . :.: : . .:.. :.: : .:. : CCDS60 GAE--PVAAWWSQEGPGEAGGWT--SEGCQLRSSQPNVSALHCQHL-GNVAV------LM 710 720 730 740 750 730 740 750 760 770 780 pF1KB7 TVLSLPRY---PGEFLHPVVYACTAVMLLCLLASFVTYIVHQSAIRISRKGRHTLLNFCF . ..:: : :::::: :::..::::.:...:::...:.::.:::: : :::.:: CCDS60 ELSAFPREVGGAGAGLHPVVYPCTALLLLCLFATIITYILNHSSIRVSRKGWHMLLNLCF 760 770 780 790 800 810 790 800 810 820 830 840 pF1KB7 HAALTFTVFAGGINRTKYPILCQAVGIVLHYSTLSTMLWIGVTARNIYKQVTKKAPLCLD : :.: .::::::. :.: ..::::::.::::.:::.::.:: :: ..:..: .:: . CCDS60 HIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQE 820 830 840 850 860 870 850 860 870 880 890 900 pF1KB7 TDQPPYPR-QPLLRFYLVSGGVPFIICGVTAATNIRNYGTEDEDTACWMAWEPSLGAFYG : : : .:.:::::..::.:.::::.:::.::.:: .:.. ::..:.::::::: CCDS60 GD-PALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNY--RDHSPYCWLVWRPSLGAFYI 880 890 900 910 920 930 910 920 930 940 pF1KB7 PAAIITLVTCVYFLGTYVQLR----RHP--GRRYELRTQPEEQR-----RLATP---EGG :.:.: :.: .::: . ..:: ..: : :: : : . : ..: CCDS60 PVALILLITWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRGSGPLLSDSG 940 950 960 970 980 990 950 960 970 980 990 1000 pF1KB7 R-----GIRPGTP-PAHDAPGASVLQNEHSFQAQLRAAAFTLFLFTATWAFGALAVSQGH . : ::: : .: : :. .: .:: : . : ::. : :: ::::::: CCDS60 SLLATGSARVGTPGPPED--GDSL----YSPGVQLGALVTTHFLYLAMWACGALAVSQRW 1000 1010 1020 1030 1040 1010 1020 1030 1040 1050 1060 pF1KB7 FLDMVFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWACCPPRKDAHPALDANGAALGRA . .: :::::. .:::::. ::::.:.:: : ::::: . : : : :: : CCDS60 LPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRACCPPASPAAP--HAPPRALPAA 1050 1060 1070 1080 1090 1100 1070 1080 1090 1100 pF1KB7 ACLHSPGLGQ--------PRGFAHPP---GPCKMTNLQAAQGHASCLSPATPCCAKMHCE : :: .:. : : . : ::::.:::: ::... : . :. : . : CCDS60 AEDGSPVFGEGPPSLKSSPSGSSGHPLALGPCKLTNLQLAQSQV-CEAGAA---AGGEGE 1110 1120 1130 1140 1150 1110 1120 1130 1140 1150 1160 pF1KB7 PLTA----DEAHVHLQE--EGAFGHDPHLHGCLQGRTKPPYFSRHPAEEPEYAYHIPSSL : : . :: : .. .: .: . .: :.. . : .. :: CCDS60 PEPAGTRGNLAHRHPNNVHHGRRAHKSRAKGHRAGEACGKNRLKALRGGAAGALELLSSE 1160 1170 1180 1190 1200 1210 1170 1180 1190 1200 1210 1220 pF1KB7 DGSPRSSRTDSP-PSSLDGPAGTHTLACCTQGDPFPMVTQPEGSDGSPALYSCPTQPG-- .:: ..: ::: :: ..:.. : .:.: :.: :::: : : : . : CCDS60 SGSLHNSPTDSYLGSSRNSPGAGLQL----EGEP--MLTPSEGSDTSAAPLSEAGRAGQR 1220 1230 1240 1250 1260 1270 1230 1240 1250 1260 1270 pF1KB7 ----REAALGPGHLEMLRRTQSLPFGGPSQNGLPKGKLLEGLPF-GTD--GTGNIRTGPW :.. : : :: . .: :... : :: ::: . . . :.. . : ..:: : CCDS60 RSASRDSLKGGGALEKESHRRSYPLNAASLNGAPKGGKYDDVTLMGAEVASGGCMKTGLW 1280 1290 1300 1310 1320 1330 pF1KB7 KNETTV :.:::: CCDS60 KSETTV 1279 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:40:11 2016 done: Sat Nov 5 08:40:12 2016 Total Scan time: 5.870 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]