FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7324, 1279 aa
1>>>pF1KB7324 1279 - 1279 aa - 1279 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9069+/-0.000824; mu= 17.3951+/- 0.050
mean_var=141.9385+/-28.496, 0's: 0 Z-trim(113.2): 29 B-trim: 147 in 1/51
Lambda= 0.107653
statistics sampled from 13788 (13817) to 13788 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.424), width: 16
Scan time: 5.870
The best scores are: opt bits E(32554)
CCDS41580.1 ADGRA1 gene_id:84435|Hs108|chr10 ( 560) 3956 626.4 6.2e-179
CCDS76362.1 ADGRA1 gene_id:84435|Hs108|chr10 ( 463) 3324 528.2 1.9e-149
CCDS33964.1 ADGRA3 gene_id:166647|Hs108|chr4 (1321) 1232 203.7 2.7e-51
CCDS6097.2 ADGRA2 gene_id:25960|Hs108|chr8 (1338) 781 133.6 3.3e-30
>>CCDS41580.1 ADGRA1 gene_id:84435|Hs108|chr10 (560 aa)
initn: 2866 init1: 2866 opt: 3956 Z-score: 3325.9 bits: 626.4 E(32554): 6.2e-179
Smith-Waterman score: 3956; 99.8% identity (99.8% similar) in 559 aa overlap (722-1279:2-560)
700 710 720 730 740 750
pF1KB7 GLVLAGRTRSVASGGKQELSGPLAACIPTQDLKTVLSLPRYPGEFLHPVVYACTAVMLLC
::::::::::::::::::::::::::::::
CCDS41 MDLKTVLSLPRYPGEFLHPVVYACTAVMLLC
10 20 30
760 770 780 790 800 810
pF1KB7 LLASFVTYIVHQSAIRISRKGRHTLLNFCFHAALTFTVFAGGINRTKYPILCQAVGIVLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 LLASFVTYIVHQSAIRISRKGRHTLLNFCFHAALTFTVFAGGINRTKYPILCQAVGIVLH
40 50 60 70 80 90
820 830 840 850 860 870
pF1KB7 YSTLSTMLWIGVTARNIYKQVTKKAPLCLDTDQPPYPRQPLLRFYLVSGGVPFIICGVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 YSTLSTMLWIGVTARNIYKQVTKKAPLCLDTDQPPYPRQPLLRFYLVSGGVPFIICGVTA
100 110 120 130 140 150
880 890 900 910 920 930
pF1KB7 ATNIRNYGTEDEDTA-CWMAWEPSLGAFYGPAAIITLVTCVYFLGTYVQLRRHPGRRYEL
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
CCDS41 ATNIRNYGTEDEDTAYCWMAWEPSLGAFYGPAAIITLVTCVYFLGTYVQLRRHPGRRYEL
160 170 180 190 200 210
940 950 960 970 980 990
pF1KB7 RTQPEEQRRLATPEGGRGIRPGTPPAHDAPGASVLQNEHSFQAQLRAAAFTLFLFTATWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 RTQPEEQRRLATPEGGRGIRPGTPPAHDAPGASVLQNEHSFQAQLRAAAFTLFLFTATWA
220 230 240 250 260 270
1000 1010 1020 1030 1040 1050
pF1KB7 FGALAVSQGHFLDMVFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWACCPPRKDAHPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 FGALAVSQGHFLDMVFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWACCPPRKDAHPAL
280 290 300 310 320 330
1060 1070 1080 1090 1100 1110
pF1KB7 DANGAALGRAACLHSPGLGQPRGFAHPPGPCKMTNLQAAQGHASCLSPATPCCAKMHCEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 DANGAALGRAACLHSPGLGQPRGFAHPPGPCKMTNLQAAQGHASCLSPATPCCAKMHCEP
340 350 360 370 380 390
1120 1130 1140 1150 1160 1170
pF1KB7 LTADEAHVHLQEEGAFGHDPHLHGCLQGRTKPPYFSRHPAEEPEYAYHIPSSLDGSPRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 LTADEAHVHLQEEGAFGHDPHLHGCLQGRTKPPYFSRHPAEEPEYAYHIPSSLDGSPRSS
400 410 420 430 440 450
1180 1190 1200 1210 1220 1230
pF1KB7 RTDSPPSSLDGPAGTHTLACCTQGDPFPMVTQPEGSDGSPALYSCPTQPGREAALGPGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 RTDSPPSSLDGPAGTHTLACCTQGDPFPMVTQPEGSDGSPALYSCPTQPGREAALGPGHL
460 470 480 490 500 510
1240 1250 1260 1270
pF1KB7 EMLRRTQSLPFGGPSQNGLPKGKLLEGLPFGTDGTGNIRTGPWKNETTV
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 EMLRRTQSLPFGGPSQNGLPKGKLLEGLPFGTDGTGNIRTGPWKNETTV
520 530 540 550 560
>>CCDS76362.1 ADGRA1 gene_id:84435|Hs108|chr10 (463 aa)
initn: 2866 init1: 2866 opt: 3324 Z-score: 2796.5 bits: 528.2 E(32554): 1.9e-149
Smith-Waterman score: 3324; 99.8% identity (99.8% similar) in 463 aa overlap (818-1279:1-463)
790 800 810 820 830 840
pF1KB7 TVFAGGINRTKYPILCQAVGIVLHYSTLSTMLWIGVTARNIYKQVTKKAPLCLDTDQPPY
::::::::::::::::::::::::::::::
CCDS76 MLWIGVTARNIYKQVTKKAPLCLDTDQPPY
10 20 30
850 860 870 880 890 900
pF1KB7 PRQPLLRFYLVSGGVPFIICGVTAATNIRNYGTEDEDTA-CWMAWEPSLGAFYGPAAIIT
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
CCDS76 PRQPLLRFYLVSGGVPFIICGVTAATNIRNYGTEDEDTAYCWMAWEPSLGAFYGPAAIIT
40 50 60 70 80 90
910 920 930 940 950 960
pF1KB7 LVTCVYFLGTYVQLRRHPGRRYELRTQPEEQRRLATPEGGRGIRPGTPPAHDAPGASVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 LVTCVYFLGTYVQLRRHPGRRYELRTQPEEQRRLATPEGGRGIRPGTPPAHDAPGASVLQ
100 110 120 130 140 150
970 980 990 1000 1010 1020
pF1KB7 NEHSFQAQLRAAAFTLFLFTATWAFGALAVSQGHFLDMVFSCLYGAFCVTLGLFVLIHHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 NEHSFQAQLRAAAFTLFLFTATWAFGALAVSQGHFLDMVFSCLYGAFCVTLGLFVLIHHC
160 170 180 190 200 210
1030 1040 1050 1060 1070 1080
pF1KB7 AKREDVWQCWWACCPPRKDAHPALDANGAALGRAACLHSPGLGQPRGFAHPPGPCKMTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 AKREDVWQCWWACCPPRKDAHPALDANGAALGRAACLHSPGLGQPRGFAHPPGPCKMTNL
220 230 240 250 260 270
1090 1100 1110 1120 1130 1140
pF1KB7 QAAQGHASCLSPATPCCAKMHCEPLTADEAHVHLQEEGAFGHDPHLHGCLQGRTKPPYFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 QAAQGHASCLSPATPCCAKMHCEPLTADEAHVHLQEEGAFGHDPHLHGCLQGRTKPPYFS
280 290 300 310 320 330
1150 1160 1170 1180 1190 1200
pF1KB7 RHPAEEPEYAYHIPSSLDGSPRSSRTDSPPSSLDGPAGTHTLACCTQGDPFPMVTQPEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 RHPAEEPEYAYHIPSSLDGSPRSSRTDSPPSSLDGPAGTHTLACCTQGDPFPMVTQPEGS
340 350 360 370 380 390
1210 1220 1230 1240 1250 1260
pF1KB7 DGSPALYSCPTQPGREAALGPGHLEMLRRTQSLPFGGPSQNGLPKGKLLEGLPFGTDGTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 DGSPALYSCPTQPGREAALGPGHLEMLRRTQSLPFGGPSQNGLPKGKLLEGLPFGTDGTG
400 410 420 430 440 450
1270
pF1KB7 NIRTGPWKNETTV
:::::::::::::
CCDS76 NIRTGPWKNETTV
460
>>CCDS33964.1 ADGRA3 gene_id:166647|Hs108|chr4 (1321 aa)
initn: 1424 init1: 964 opt: 1232 Z-score: 1034.5 bits: 203.7 E(32554): 2.7e-51
Smith-Waterman score: 1433; 43.3% identity (67.1% similar) in 571 aa overlap (736-1279:758-1321)
710 720 730 740 750 760
pF1KB7 GKQELSGPLAACIPTQDLKTVLSLPRYPGEFLHPVVYACTAVMLLCLLASFVTYIVHQSA
.::::::. . ..:::::: .:.:: :.:
CCDS33 NITTIQCYSLSNYAVLMDLTGSELYTQAASLLHPVVYTTAIILLLCLLAVIVSYIYHHSL
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB7 IRISRKGRHTLLNFCFHAALTFTVFAGGINRTKYPILCQAVGIVLHYSTLSTMLWIGVTA
:::: :. : :.:.::: :: .::.:::..:. .::::::.::::::.:.::.::::
CCDS33 IRISLKSWHMLVNLCFHIFLTCVVFVGGITQTRNASICQAVGIILHYSTLATVLWVGVTA
790 800 810 820 830 840
830 840 850 860 870 880
pF1KB7 RNIYKQVTKKAPLCLDTDQPPYPRQPLLRFYLVSGGVPFIICGVTAATNIRNYGTEDEDT
::::::::::: : : :.:: : .:.:::::..::.:.:.::.:::.::.:::.. .
CCDS33 RNIYKQVTKKAKRCQDPDEPPPPPRPMLRFYLIGGGIPIIVCGITAAANIKNYGSRPNAP
850 860 870 880 890 900
890 900 910 920 930 940
pF1KB7 ACWMAWEPSLGAFYGPAAIITLVTCVYFLGTYVQLRRHPGRRYELRTQPEEQRRLATPEG
::::::::::::::::..::.:.:.:::. ..::.::: :.:::. :::.:::. :.
CCDS33 YCWMAWEPSLGAFYGPASFITFVNCMYFLSIFIQLKRHPERKYELKEPTEEQQRLAANEN
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KB7 GRGIRPGTPPAHDAPGASVLQNEHSFQAQLRAAAFTLFLFTATWAFGALAVSQGHFLDMV
:. : . . ..:.:.:::.:..:: .:..::.:..: : ::::::: . ::.:
CCDS33 GE-INHQDSMSLSLISTSALENEHTFHSQLLGASLTLLLYVALWMFGALAVSLYYPLDLV
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050
pF1KB7 FSCLYGAFCVTLGLFVLIHHCAKREDVWQCW-WACCPPRK------DAHPALDANGAALG
:: ..:: .... : ..:::..:::: : .::: :. ...: ..::.
CCDS33 FSFVFGATSLSFSAFFVVHHCVNREDVRLAWIMTCCPGRSSYSVQVNVQPP-NSNGTNGE
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KB7 RAACLHSPGLGQ-----PRGFAHPPGPCKMTNLQAA--QGHASCLS-PATPCCAKMHCEP
: .: . .. .: . ::.:::::: : ::. : .:: . :
CCDS33 APKCPNSSAESSCTNKSASSFKNSSQGCKLTNLQAAAAQCHANSLPLNSTPQLDNSLTEH
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160
pF1KB7 LTADEAHVHLQE-EGAFGHDPHLHGCLQGRTKPPYFSRHPAEEPEYAYHIPSSLDGSPRS
.. ..:. : : . : ..:.: :: . . :::: .:.:..:: ..
CCDS33 SMDNDIKMHVAPLEVQFRTNVHSSRHHKNRSKGHRASRLTVLR-EYAYDVPTSVEGSVQN
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210
pF1KB7 SRTDSPPSSLDGPAGTHTLACCTQGDPFPMVTQPEGSDGSPALYSCP-----------TQ
. : : : . : :. . . .: .:.: : . : :
CCDS33 GL---PKSRLGNNEG-HSRSRRAYLAYRERQYNPPQQDSSDACSTLPKSSRNFEKPVSTT
1210 1220 1230 1240 1250 1260
1220 1230 1240 1250 1260 1270
pF1KB7 PGREAALGPGHLEMLRRTQSLPFGGPSQNGLPKGKLLEGLPFGTDGTGNIRTGPWKNETT
..: :. .:. . .: .. ::: :.. :: .:::.:::.::: ::.:::
CCDS33 SKKDALRKPAVVELENQQKSYGLNLAIQNGPIKSNGQEGPLLGTDSTGNVRTGLWKHETT
1270 1280 1290 1300 1310 1320
pF1KB7 V
:
CCDS33 V
>>CCDS6097.2 ADGRA2 gene_id:25960|Hs108|chr8 (1338 aa)
initn: 1121 init1: 604 opt: 781 Z-score: 655.9 bits: 133.6 E(32554): 3.3e-30
Smith-Waterman score: 1223; 39.5% identity (60.6% similar) in 696 aa overlap (637-1279:681-1338)
610 620 630 640 650 660
pF1KB7 TPHCVGKKVPQPVGAADLAPDTSLCRKEGSSASRSCRPGPGHLTRREEDSFRQLAFPRFE
... .: : :.::. :.:. : :
CCDS60 GRLFHSHSNTSRPGAAGPGKRRGVATPVIFAGTSGC--GVGNLTEPVAVSLRHWA----E
660 670 680 690 700
670 680 690 700 710 720
pF1KB7 EVTFPPLTA--AERAPSVHGGHSLASQGLVLAGRTRSVASGGKQELSGPLAACIPTQDLK
. :..: ....:. :: . :.: : . .:.. :.: : .:. :
CCDS60 GAE--PVAAWWSQEGPGEAGGWT--SEGCQLRSSQPNVSALHCQHL-GNVAV------LM
710 720 730 740 750
730 740 750 760 770 780
pF1KB7 TVLSLPRY---PGEFLHPVVYACTAVMLLCLLASFVTYIVHQSAIRISRKGRHTLLNFCF
. ..:: : :::::: :::..::::.:...:::...:.::.:::: : :::.::
CCDS60 ELSAFPREVGGAGAGLHPVVYPCTALLLLCLFATIITYILNHSSIRVSRKGWHMLLNLCF
760 770 780 790 800 810
790 800 810 820 830 840
pF1KB7 HAALTFTVFAGGINRTKYPILCQAVGIVLHYSTLSTMLWIGVTARNIYKQVTKKAPLCLD
: :.: .::::::. :.: ..::::::.::::.:::.::.:: :: ..:..: .:: .
CCDS60 HIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQE
820 830 840 850 860 870
850 860 870 880 890 900
pF1KB7 TDQPPYPR-QPLLRFYLVSGGVPFIICGVTAATNIRNYGTEDEDTACWMAWEPSLGAFYG
: : : .:.:::::..::.:.::::.:::.::.:: .:.. ::..:.:::::::
CCDS60 GD-PALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNY--RDHSPYCWLVWRPSLGAFYI
880 890 900 910 920 930
910 920 930 940
pF1KB7 PAAIITLVTCVYFLGTYVQLR----RHP--GRRYELRTQPEEQR-----RLATP---EGG
:.:.: :.: .::: . ..:: ..: : :: : : . : ..:
CCDS60 PVALILLITWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRGSGPLLSDSG
940 950 960 970 980 990
950 960 970 980 990 1000
pF1KB7 R-----GIRPGTP-PAHDAPGASVLQNEHSFQAQLRAAAFTLFLFTATWAFGALAVSQGH
. : ::: : .: : :. .: .:: : . : ::. : :: :::::::
CCDS60 SLLATGSARVGTPGPPED--GDSL----YSPGVQLGALVTTHFLYLAMWACGALAVSQRW
1000 1010 1020 1030 1040
1010 1020 1030 1040 1050 1060
pF1KB7 FLDMVFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWACCPPRKDAHPALDANGAALGRA
. .: :::::. .:::::. ::::.:.:: : ::::: . : : : :: :
CCDS60 LPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRACCPPASPAAP--HAPPRALPAA
1050 1060 1070 1080 1090 1100
1070 1080 1090 1100
pF1KB7 ACLHSPGLGQ--------PRGFAHPP---GPCKMTNLQAAQGHASCLSPATPCCAKMHCE
: :: .:. : : . : ::::.:::: ::... : . :. : . :
CCDS60 AEDGSPVFGEGPPSLKSSPSGSSGHPLALGPCKLTNLQLAQSQV-CEAGAA---AGGEGE
1110 1120 1130 1140 1150
1110 1120 1130 1140 1150 1160
pF1KB7 PLTA----DEAHVHLQE--EGAFGHDPHLHGCLQGRTKPPYFSRHPAEEPEYAYHIPSSL
: : . :: : .. .: .: . .: :.. . : .. ::
CCDS60 PEPAGTRGNLAHRHPNNVHHGRRAHKSRAKGHRAGEACGKNRLKALRGGAAGALELLSSE
1160 1170 1180 1190 1200 1210
1170 1180 1190 1200 1210 1220
pF1KB7 DGSPRSSRTDSP-PSSLDGPAGTHTLACCTQGDPFPMVTQPEGSDGSPALYSCPTQPG--
.:: ..: ::: :: ..:.. : .:.: :.: :::: : : : . :
CCDS60 SGSLHNSPTDSYLGSSRNSPGAGLQL----EGEP--MLTPSEGSDTSAAPLSEAGRAGQR
1220 1230 1240 1250 1260 1270
1230 1240 1250 1260 1270
pF1KB7 ----REAALGPGHLEMLRRTQSLPFGGPSQNGLPKGKLLEGLPF-GTD--GTGNIRTGPW
:.. : : :: . .: :... : :: ::: . . . :.. . : ..:: :
CCDS60 RSASRDSLKGGGALEKESHRRSYPLNAASLNGAPKGGKYDDVTLMGAEVASGGCMKTGLW
1280 1290 1300 1310 1320 1330
pF1KB7 KNETTV
:.::::
CCDS60 KSETTV
1279 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:40:11 2016 done: Sat Nov 5 08:40:12 2016
Total Scan time: 5.870 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]