FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7325, 1649 aa 1>>>pF1KB7325 1649 - 1649 aa - 1649 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.5910+/-0.0015; mu= -15.3451+/- 0.087 mean_var=564.0191+/-129.753, 0's: 0 Z-trim(109.7): 78 B-trim: 645 in 1/51 Lambda= 0.054004 statistics sampled from 11024 (11074) to 11024 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.34), width: 16 Scan time: 6.390 The best scores are: opt bits E(32554) CCDS42016.1 EIF2AK4 gene_id:440275|Hs108|chr15 (1649) 10902 866.5 0 >>CCDS42016.1 EIF2AK4 gene_id:440275|Hs108|chr15 (1649 aa) initn: 10902 init1: 10902 opt: 10902 Z-score: 4613.0 bits: 866.5 E(32554): 0 Smith-Waterman score: 10902; 100.0% identity (100.0% similar) in 1649 aa overlap (1-1649:1-1649) 10 20 30 40 50 60 pF1KB7 MAGGRGAPGRGRDEPPESYPQRQDHELQALEAIYGADFQDLRPDACGPVKEPPEINLVLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MAGGRGAPGRGRDEPPESYPQRQDHELQALEAIYGADFQDLRPDACGPVKEPPEINLVLY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PQGLTGEEVYVKVDLRVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSRLEELAKKHCGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PQGLTGEEVYVKVDLRVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSRLEELAKKHCGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VMIFELAYHVQSFLSEHNKPPPKSFHEEMLERRAQEEQQRLLEAKRKEEQEQREILHEIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VMIFELAYHVQSFLSEHNKPPPKSFHEEMLERRAQEEQQRLLEAKRKEEQEQREILHEIQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 RRKEEIKEEKKRKEMAKQERLEIASLSNQDHTSKKDPGGHRTAAILHGGSPDFVGNGKHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RRKEEIKEEKKRKEMAKQERLEIASLSNQDHTSKKDPGGHRTAAILHGGSPDFVGNGKHR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 ANSSGRSRRERQYSVCNSEDSPGSCEILYFNMGSPDQLMVHKGKCIGSDEQLGKLVYNAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ANSSGRSRRERQYSVCNSEDSPGSCEILYFNMGSPDQLMVHKGKCIGSDEQLGKLVYNAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 ETATGGFVLLYEWVLQWQKKMGPFLTSQEKEKIDKCKKQIQGTETEFNSLVKLSHPNVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ETATGGFVLLYEWVLQWQKKMGPFLTSQEKEKIDKCKKQIQGTETEFNSLVKLSHPNVVR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 YLAMNLKEQDDSIVVDILVEHISGVSLAAHLSHSGPIPVHQLRRYTAQLLSGLDYLHSNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 YLAMNLKEQDDSIVVDILVEHISGVSLAAHLSHSGPIPVHQLRRYTAQLLSGLDYLHSNS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 VVHKVLSASNVLVDAEGTVKITDYSISKRLADICKEDVFEQTRVRFSDNALPYKTGKKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VVHKVLSASNVLVDAEGTVKITDYSISKRLADICKEDVFEQTRVRFSDNALPYKTGKKGD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 VWRLGLLLLSLSQGQECGEYPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VWRLGLLLLSLSQGQECGEYPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFIN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 PQPKMPLVEQSPEDSEGQDYVETVIPSNRLPSAAFFSETQRQFSRYFIEFEELQLLGKGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PQPKMPLVEQSPEDSEGQDYVETVIPSNRLPSAAFFSETQRQFSRYFIEFEELQLLGKGA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 FGAVIKVQNKLDGCCYAVKRIPINPASRQFRRIKGEVTLLSRLHHENIVRYYNAWIERHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 FGAVIKVQNKLDGCCYAVKRIPINPASRQFRRIKGEVTLLSRLHHENIVRYYNAWIERHE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 RPAGPGTPPPDSGPLAKDDRAARGQPASDTDGLDSVEAAAPPPILSSSVEWSTSGERSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RPAGPGTPPPDSGPLAKDDRAARGQPASDTDGLDSVEAAAPPPILSSSVEWSTSGERSAS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 ARFPATGPGSSDDEDDDEDEHGGVFSQSFLPASDSESDIIFDNEDENSKSQNQDEDCNEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ARFPATGPGSSDDEDDDEDEHGGVFSQSFLPASDSESDIIFDNEDENSKSQNQDEDCNEK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 NGCHESEPSVTTEAVHYLYIQMEYCEKSTLRDTIDQGLYRDTVRLWRLFREILDGLAYIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 NGCHESEPSVTTEAVHYLYIQMEYCEKSTLRDTIDQGLYRDTVRLWRLFREILDGLAYIH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 EKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFSADSKQDDQTGDLIKSDPSGHLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFSADSKQDDQTGDLIKSDPSGHLTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 MVGTALYVSPEVQGSTKSAYNQKVDLFSLGIIFFEMSYHPMVTASERIFVLNQLRDPTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MVGTALYVSPEVQGSTKSAYNQKVDLFSLGIIFFEMSYHPMVTASERIFVLNQLRDPTSP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 KFPEDFDDGEHAKQKSVISWLLNHDPAKRPTATELLKSELLPPPQMEESELHEVLHHTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 KFPEDFDDGEHAKQKSVISWLLNHDPAKRPTATELLKSELLPPPQMEESELHEVLHHTLT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB7 NVDGKAYRTMMAQIFSQRISPAIDYTYDSDILKGNFSIRTAKMQQHVCETIIRIFKRHGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 NVDGKAYRTMMAQIFSQRISPAIDYTYDSDILKGNFSIRTAKMQQHVCETIIRIFKRHGA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB7 VQLCTPLLLPRNRQIYEHNEAALFMDHSGMLVMLPFDLRIPFARYVARNNILNLKRYCIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VQLCTPLLLPRNRQIYEHNEAALFMDHSGMLVMLPFDLRIPFARYVARNNILNLKRYCIE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB7 RVFRPRKLDRFHPKELLECAFDIVTSTTNSFLPTAEIIYTIYEIIQEFPALQERNYSIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RVFRPRKLDRFHPKELLECAFDIVTSTTNSFLPTAEIIYTIYEIIQEFPALQERNYSIYL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB7 NHTMLLKAILLHCGIPEDKLSQVYIILYDAVTEKLTRREVEAKFCNLSLSSNSLCRLYKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 NHTMLLKAILLHCGIPEDKLSQVYIILYDAVTEKLTRREVEAKFCNLSLSSNSLCRLYKF 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB7 IEQKGDLQDLMPTINSLIKQKTGIAQLVKYGLKDLEEVVGLLKKLGIKLQVLINLGLVYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 IEQKGDLQDLMPTINSLIKQKTGIAQLVKYGLKDLEEVVGLLKKLGIKLQVLINLGLVYK 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB7 VQQHNGIIFQFVAFIKRRQRAVPEILAAGGRYDLLIPQFRGPQALGPVPTAIGVSIAIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VQQHNGIIFQFVAFIKRRQRAVPEILAAGGRYDLLIPQFRGPQALGPVPTAIGVSIAIDK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB7 ISAAVLNMEESVTISSCDLLVVSVGQMSMSRAINLTQKLWTAGITAEIMYDWSQSQEELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ISAAVLNMEESVTISSCDLLVVSVGQMSMSRAINLTQKLWTAGITAEIMYDWSQSQEELQ 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB7 EYCRHHEITYVALVSDKEGSHVKVKSFEKERQTEKRVLETELVDHVLQKLRTKVTDERNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EYCRHHEITYVALVSDKEGSHVKVKSFEKERQTEKRVLETELVDHVLQKLRTKVTDERNG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB7 REASDNLAVQNLKGSFSNASGLFEIHGATVVPIVSVLAPEKLSASTRRRYETQVQTRLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 REASDNLAVQNLKGSFSNASGLFEIHGATVVPIVSVLAPEKLSASTRRRYETQVQTRLQT 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB7 SLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTTVKQLLSRLPKQRYLKLVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTTVKQLLSRLPKQRYLKLVC 1570 1580 1590 1600 1610 1620 1630 1640 pF1KB7 DEIYNIKVEKKVSVLFLYSYRDDYYRILF ::::::::::::::::::::::::::::: CCDS42 DEIYNIKVEKKVSVLFLYSYRDDYYRILF 1630 1640 1649 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:43:01 2016 done: Sat Nov 5 02:43:02 2016 Total Scan time: 6.390 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]