FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7326, 1215 aa 1>>>pF1KB7326 1215 - 1215 aa - 1215 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 15.3689+/-0.000626; mu= -28.7739+/- 0.038 mean_var=696.5429+/-156.601, 0's: 0 Z-trim(115.4): 848 B-trim: 1335 in 1/56 Lambda= 0.048596 statistics sampled from 24765 (25828) to 24765 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.303), width: 16 Scan time: 15.190 The best scores are: opt bits E(85289) NP_005725 (OMIM: 604424) homeodomain-interacting p (1215) 8177 590.7 1.9e-167 XP_016872565 (OMIM: 604424) PREDICTED: homeodomain (1215) 8177 590.7 1.9e-167 XP_005252786 (OMIM: 604424) PREDICTED: homeodomain (1215) 8177 590.7 1.9e-167 XP_016872566 (OMIM: 604424) PREDICTED: homeodomain (1194) 5187 381.1 2.4e-104 NP_001265091 (OMIM: 604424) homeodomain-interactin (1194) 5187 381.1 2.4e-104 NP_001265092 (OMIM: 604424) homeodomain-interactin (1194) 5187 381.1 2.4e-104 NP_001041665 (OMIM: 604424) homeodomain-interactin (1194) 5187 381.1 2.4e-104 XP_011514382 (OMIM: 606868) PREDICTED: homeodomain (1349) 3115 235.8 1.4e-60 NP_001106710 (OMIM: 606868) homeodomain-interactin (1171) 3002 227.9 3.1e-58 XP_011514381 (OMIM: 606868) PREDICTED: homeodomain (1350) 3002 227.9 3.4e-58 XP_016856094 (OMIM: 608003) PREDICTED: homeodomain (1209) 2946 224.0 4.8e-57 XP_005270667 (OMIM: 608003) PREDICTED: homeodomain (1280) 2946 224.0 5e-57 XP_005270669 (OMIM: 608003) PREDICTED: homeodomain (1210) 2944 223.8 5.3e-57 NP_938009 (OMIM: 608003) homeodomain-interacting p (1210) 2944 223.8 5.3e-57 XP_005270670 (OMIM: 608003) PREDICTED: homeodomain (1210) 2944 223.8 5.3e-57 XP_005270666 (OMIM: 608003) PREDICTED: homeodomain (1281) 2944 223.8 5.5e-57 XP_006710506 (OMIM: 608003) PREDICTED: homeodomain (1247) 2722 208.3 2.6e-52 XP_005270668 (OMIM: 608003) PREDICTED: homeodomain (1256) 2587 198.8 1.9e-49 NP_689909 (OMIM: 608003) homeodomain-interacting p (1075) 2580 198.3 2.3e-49 XP_011514380 (OMIM: 606868) PREDICTED: homeodomain (1376) 2577 198.1 3.2e-49 XP_006715998 (OMIM: 606868) PREDICTED: homeodomain (1191) 2570 197.6 4.1e-49 XP_016867558 (OMIM: 606868) PREDICTED: homeodomain (1191) 2570 197.6 4.1e-49 NP_073577 (OMIM: 606868) homeodomain-interacting p (1198) 2570 197.6 4.1e-49 XP_011514383 (OMIM: 606868) PREDICTED: homeodomain (1206) 2570 197.6 4.1e-49 XP_011514379 (OMIM: 606868) PREDICTED: homeodomain (1377) 2570 197.6 4.6e-49 XP_016856095 (OMIM: 608003) PREDICTED: homeodomain ( 605) 2352 182.1 9.8e-45 XP_011539279 (OMIM: 608003) PREDICTED: homeodomain (1241) 2063 162.1 2.1e-38 NP_938010 (OMIM: 608003) homeodomain-interacting p ( 836) 1404 115.7 1.3e-24 NP_852003 (OMIM: 608003) homeodomain-interacting p ( 816) 1224 103.1 7.9e-21 NP_653286 (OMIM: 611712) homeodomain-interacting p ( 616) 1095 93.9 3.4e-18 XP_006723099 (OMIM: 611712) PREDICTED: homeodomain ( 619) 1095 93.9 3.4e-18 NP_569122 (OMIM: 600855,614104) dual specificity t ( 529) 746 69.4 7e-11 NP_567824 (OMIM: 600855,614104) dual specificity t ( 584) 746 69.4 7.5e-11 XP_011527787 (OMIM: 600855,614104) PREDICTED: dual ( 725) 746 69.5 8.8e-11 XP_016883775 (OMIM: 600855,614104) PREDICTED: dual ( 734) 746 69.5 8.9e-11 XP_016883773 (OMIM: 600855,614104) PREDICTED: dual ( 754) 746 69.5 9.1e-11 XP_006724042 (OMIM: 600855,614104) PREDICTED: dual ( 754) 746 69.5 9.1e-11 XP_016883774 (OMIM: 600855,614104) PREDICTED: dual ( 754) 746 69.5 9.1e-11 NP_569120 (OMIM: 600855,614104) dual specificity t ( 754) 746 69.5 9.1e-11 XP_011527786 (OMIM: 600855,614104) PREDICTED: dual ( 761) 746 69.5 9.2e-11 XP_006724039 (OMIM: 600855,614104) PREDICTED: dual ( 763) 746 69.5 9.2e-11 XP_011527785 (OMIM: 600855,614104) PREDICTED: dual ( 763) 746 69.5 9.2e-11 NP_001387 (OMIM: 600855,614104) dual specificity t ( 763) 746 69.5 9.2e-11 XP_006724040 (OMIM: 600855,614104) PREDICTED: dual ( 763) 746 69.5 9.2e-11 XP_006724041 (OMIM: 600855,614104) PREDICTED: dual ( 763) 746 69.5 9.2e-11 XP_011527784 (OMIM: 600855,614104) PREDICTED: dual ( 770) 746 69.5 9.2e-11 XP_005259455 (OMIM: 604556,615812) PREDICTED: dual ( 629) 713 67.2 3.9e-10 NP_004705 (OMIM: 604556,615812) dual specificity t ( 629) 713 67.2 3.9e-10 NP_006474 (OMIM: 604556,615812) dual specificity t ( 589) 700 66.2 7.1e-10 NP_006475 (OMIM: 604556,615812) dual specificity t ( 601) 700 66.2 7.2e-10 >>NP_005725 (OMIM: 604424) homeodomain-interacting prote (1215 aa) initn: 8177 init1: 8177 opt: 8177 Z-score: 3127.1 bits: 590.7 E(85289): 1.9e-167 Smith-Waterman score: 8177; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215) 10 20 30 40 50 60 pF1KB7 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 GREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB7 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB7 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB7 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT 1150 1160 1170 1180 1190 1200 1210 pF1KB7 GFPLSPTKLSQYPYM ::::::::::::::: NP_005 GFPLSPTKLSQYPYM 1210 >>XP_016872565 (OMIM: 604424) PREDICTED: homeodomain-int (1215 aa) initn: 8177 init1: 8177 opt: 8177 Z-score: 3127.1 bits: 590.7 E(85289): 1.9e-167 Smith-Waterman score: 8177; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215) 10 20 30 40 50 60 pF1KB7 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 GREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB7 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB7 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB7 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT 1150 1160 1170 1180 1190 1200 1210 pF1KB7 GFPLSPTKLSQYPYM ::::::::::::::: XP_016 GFPLSPTKLSQYPYM 1210 >>XP_005252786 (OMIM: 604424) PREDICTED: homeodomain-int (1215 aa) initn: 8177 init1: 8177 opt: 8177 Z-score: 3127.1 bits: 590.7 E(85289): 1.9e-167 Smith-Waterman score: 8177; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215) 10 20 30 40 50 60 pF1KB7 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 GREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB7 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB7 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB7 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT 1150 1160 1170 1180 1190 1200 1210 pF1KB7 GFPLSPTKLSQYPYM ::::::::::::::: XP_005 GFPLSPTKLSQYPYM 1210 >>XP_016872566 (OMIM: 604424) PREDICTED: homeodomain-int (1194 aa) initn: 8013 init1: 5158 opt: 5187 Z-score: 1994.3 bits: 381.1 E(85289): 2.4e-104 Smith-Waterman score: 7975; 98.3% identity (98.3% similar) in 1215 aa overlap (1-1215:1-1194) 10 20 30 40 50 60 pF1KB7 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEP ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNR----------- 730 740 750 760 790 800 810 820 830 840 pF1KB7 GREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ----------SNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS 770 780 790 800 810 850 860 870 880 890 900 pF1KB7 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ 820 830 840 850 860 870 910 920 930 940 950 960 pF1KB7 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KB7 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KB7 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KB7 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KB7 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT 1120 1130 1140 1150 1160 1170 1210 pF1KB7 GFPLSPTKLSQYPYM ::::::::::::::: XP_016 GFPLSPTKLSQYPYM 1180 1190 >>NP_001265091 (OMIM: 604424) homeodomain-interacting pr (1194 aa) initn: 8013 init1: 5158 opt: 5187 Z-score: 1994.3 bits: 381.1 E(85289): 2.4e-104 Smith-Waterman score: 7975; 98.3% identity (98.3% similar) in 1215 aa overlap (1-1215:1-1194) 10 20 30 40 50 60 pF1KB7 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEP ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNR----------- 730 740 750 760 790 800 810 820 830 840 pF1KB7 GREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ----------SNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS 770 780 790 800 810 850 860 870 880 890 900 pF1KB7 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ 820 830 840 850 860 870 910 920 930 940 950 960 pF1KB7 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KB7 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KB7 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KB7 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KB7 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT 1120 1130 1140 1150 1160 1170 1210 pF1KB7 GFPLSPTKLSQYPYM ::::::::::::::: NP_001 GFPLSPTKLSQYPYM 1180 1190 >>NP_001265092 (OMIM: 604424) homeodomain-interacting pr (1194 aa) initn: 8013 init1: 5158 opt: 5187 Z-score: 1994.3 bits: 381.1 E(85289): 2.4e-104 Smith-Waterman score: 7975; 98.3% identity (98.3% similar) in 1215 aa overlap (1-1215:1-1194) 10 20 30 40 50 60 pF1KB7 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEP ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNR----------- 730 740 750 760 790 800 810 820 830 840 pF1KB7 GREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ----------SNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS 770 780 790 800 810 850 860 870 880 890 900 pF1KB7 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ 820 830 840 850 860 870 910 920 930 940 950 960 pF1KB7 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KB7 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KB7 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KB7 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KB7 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT 1120 1130 1140 1150 1160 1170 1210 pF1KB7 GFPLSPTKLSQYPYM ::::::::::::::: NP_001 GFPLSPTKLSQYPYM 1180 1190 >>NP_001041665 (OMIM: 604424) homeodomain-interacting pr (1194 aa) initn: 8013 init1: 5158 opt: 5187 Z-score: 1994.3 bits: 381.1 E(85289): 2.4e-104 Smith-Waterman score: 7975; 98.3% identity (98.3% similar) in 1215 aa overlap (1-1215:1-1194) 10 20 30 40 50 60 pF1KB7 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEP ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNR----------- 730 740 750 760 790 800 810 820 830 840 pF1KB7 GREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ----------SNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS 770 780 790 800 810 850 860 870 880 890 900 pF1KB7 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ 820 830 840 850 860 870 910 920 930 940 950 960 pF1KB7 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KB7 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KB7 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KB7 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KB7 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT 1120 1130 1140 1150 1160 1170 1210 pF1KB7 GFPLSPTKLSQYPYM ::::::::::::::: NP_001 GFPLSPTKLSQYPYM 1180 1190 >>XP_011514382 (OMIM: 606868) PREDICTED: homeodomain-int (1349 aa) initn: 3492 init1: 2298 opt: 3115 Z-score: 1208.5 bits: 235.8 E(85289): 1.4e-60 Smith-Waterman score: 3766; 51.6% identity (73.9% similar) in 1255 aa overlap (1-1215:187-1349) 10 20 30 pF1KB7 MASQVLVYPPYVYQTQSSAFCSVKKLKVEP :::.: :. :.. ::::::::::::.:: XP_011 LQEATLENKCQVLKRLNIESPPDLAVPLPGMASHVQVFSPHTL--QSSAFCSVKKLKIEP 160 170 180 190 200 210 40 50 60 70 80 pF1KB7 SSC--VFQERNYPRTYVNGRNFGNSHPPTKGSAFQTKIPFNRPRGHNFSLQ-TSAVVLKN :: . .. ..: ...:. :.: : .. .:..: : :: ...:. . XP_011 SSNWDMTGYGSHSKVYSQSKNIPLSQPAT--TTVSTSLPVPNP-----SLPYEQTIVFPG 220 230 240 250 260 90 100 110 120 130 140 pF1KB7 TAGATKVIAAQAQQAHVQA---PQIGAWRNRLHFLEGPQRCGLKRKSEELDNHSSAMQIV ..: : .:.. .. :. :. :. . .:. :.:::::::::..: .:..::. XP_011 STGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQKCGLKRKSEEIEN-TSSVQII 270 280 290 300 310 320 150 160 170 180 190 200 pF1KB7 DELSILPAMLQTNMGNPVTVVTATTG---SKQNCTTGEGDYQLVQHEVLCSMKNTYEVLD .: : :.:.: .. .::.::::. ::.. ...::::::::::::::: ::::::. XP_011 EEH---PPMIQNNASG-ATVATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLE 330 340 350 360 370 380 210 220 230 240 250 260 pF1KB7 FLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRA ::::::::::::::::::::::::::::::::::::::::::::::::::.::.:::::: XP_011 FLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRA 390 400 410 420 430 440 270 280 290 300 310 320 pF1KB7 YECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPILQQVATALKKLKSLGLIHA ::::::.::::::::::::::::::::::::::::: :::.:::::::: :::::::::: XP_011 YECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHA 450 460 470 480 490 500 330 340 350 360 370 380 pF1KB7 DLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAID :::::::::::: :::::::::::::::::::.::::::::::::::::::::::::::: XP_011 DLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAID 510 520 530 540 550 560 390 400 410 420 430 440 pF1KB7 MWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCKETDMSH ::::::::::::::::::::: :::::::::::::::.: ::..:::.:::: ..:: . XP_011 MWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPY 570 580 590 600 610 620 450 460 470 480 490 500 pF1KB7 SGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTVMDLEGSDLLAEKADRREFVSL ::::: ..::::::.::::::::::: :::.:.:: . ::::::.:.::::::::..: XP_011 PLWRLKTPDDHEAETGIKSKEARKYIFNCLDDMAQVNMTTDLEGSDMLVEKADRREFIDL 630 640 650 660 670 680 510 520 530 540 550 560 pF1KB7 LKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVKSCFHIMDICKSHLNSCDTNNH ::::: :::: :::: ::::::::.: ::::::::.::::::. :.::: ..: :: :. XP_011 LKKMLTIDADKRITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQ 690 700 710 720 730 740 570 580 590 600 610 pF1KB7 NKTSLLRPVASSSTATLTANFT-KIGTLRSQALTTSAHSVVHHGIPLQAGTAQFGCG--D .:: .. :: :....:: .:. .. :...: ..: .:.....:::.::::. :. : XP_011 SKTPFITHVAPSTSTNLTMTFNNQLTTVHNQPSAASMAAVAQRSMPLQTGTAQI-CARPD 750 760 770 780 790 800 620 630 640 650 660 670 pF1KB7 AFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQTWSGR :::.::.:::..::. :. .: ..::.:..:.::.:::::..:::::.::.:.:.: . XP_011 PFQQALIVCPPGFQGLQASPSKHAGYSVRMENAVPIVTQAPGAQPLQIQPGLLAQAWPSG 810 820 830 840 850 860 680 690 700 710 720 730 pF1KB7 TQQMLVP-AWQQVTPLAPATT----TLTSESVAGSHRLGDWGKMISCSNHYNSVMPQP-L :::.:.: ::::.: .: :. :. :..::...:.:: . . ..::: .: :: : XP_011 TQQILLPPAWQQLTGVATHTSVQHATVIPETMAGTQQLADWRNTHAHGSHYNPIMQQPAL 870 880 890 900 910 920 740 750 760 770 780 pF1KB7 LTNQITLSAPQPVSVGIAHVVWPQPATT---KKNKQCQNRGILVKLMEWEPGREEINAFS ::...:: : ::..::.:::. ::..: .:.:: :. :. : . . :.. . XP_011 LTGHVTLPAAQPLNVGVAHVMRQQPTSTTSSRKSKQHQSSVRNVSTCEVS-SSQAISSPQ 930 940 950 960 970 980 790 800 810 820 830 840 pF1KB7 WSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETSIRQDSDSSV :. ..... :. :.. . . .: .: . :.. ..:.. XP_011 RSKRVKENTPPRCAMVHSSPACSTSV---TC--------GWGDV-----------ASSTT 990 1000 1010 850 860 870 880 890 900 pF1KB7 SDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQSTLNIDRMC ..:::::.: :.:::.:::::::::::::: :.:. XP_011 RERQRQTIVIPDTPSPTVSVITISSDTDEEEE-QKHA----------------------- 1020 1030 1040 1050 910 920 930 940 950 960 pF1KB7 SLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGHDSPFAESTF : ::.: .: : .: : :: :: ::::.. ::.. . XP_011 ----PTSTVSK-----------QRKNVIS-------CVTVHDSPYSDSSSNTSPYSVQQR 1060 1070 1080 1090 970 980 990 1000 1010 pF1KB7 VEDTHENT-ELVSSADTETKPAVCSVVVPPVELENG-----------LNADEHMANTDSI . .. :. . .: ... ...:::.. . . .:...: .. : XP_011 AGHNNANAFDTKGSLENHCTGNPRTIIVPPLKTQASEVLVECDSLVPVNTSHHSSSYKSK 1100 1110 1120 1130 1140 1150 1020 1030 1040 1050 1060 1070 pF1KB7 CQPLIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQH-LNFSQVQHFGSGHQEWNGNFGHRR . . . :. . .. .:. :::. ::::. ::.::.:. : . . .::: XP_011 SSSNVTSTSGHSSGSSSGAITYRQQRPGPHFQQQQPLNLSQAQQ----HITTDRTGSHRR 1160 1170 1180 1190 1200 1080 1090 1100 1110 1120 1130 pF1KB7 QQAYIPTSVTSNPFTLSHGSPNHTAVHAHLAGNT---HLGGQPTLLPYPSSATLSSAAPV ::::: .... :... :.::.: .:: :::. . :: :: : : . :.:.:.. : XP_011 QQAYITPTMAQAPYSFPHNSPSHGTVHPHLAAAAAAAHLPTQPHLYTYTAPAALGSTGTV 1210 1220 1230 1240 1250 1260 1140 1150 1160 1170 1180 1190 pF1KB7 AHLLASPCTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYI :::.:: ..: .:: .: :..:::::::...::.::::::: .:: : ..:: XP_011 AHLVASQGSARHTVQHTAY----PASIVHQVPVSMGPRVLPSPTIHPSQYPAQFAHQTYI 1270 1280 1290 1300 1310 1320 1200 1210 pF1KB7 AASPA---YTGFPLSPTKLSQYPYM .:::: :::.::::.:..::::. XP_011 SASPASTVYTGYPLSPAKVNQYPYI 1330 1340 >>NP_001106710 (OMIM: 606868) homeodomain-interacting pr (1171 aa) initn: 3442 init1: 2298 opt: 3002 Z-score: 1166.5 bits: 227.9 E(85289): 3.1e-58 Smith-Waterman score: 3754; 51.5% identity (73.8% similar) in 1256 aa overlap (1-1215:8-1171) 10 20 30 40 50 pF1KB7 MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSC--VFQERNYPRTYVNGRNFG :::.: :. :.. ::::::::::::.:::: . .. ..: ...:. NP_001 MAPVYEGMASHVQVFSPHTL--QSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIP 10 20 30 40 50 60 70 80 90 100 pF1KB7 NSHPPTKGSAFQTKIPFNRPRGHNFSLQ-TSAVVLKNTAGATKVIAAQAQQAHVQA---P :.: : .. .:..: : :: ...:. ...: : .:.. .. :. : NP_001 LSQPAT--TTVSTSLPVPNP-----SLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGP 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 QIGAWRNRLHFLEGPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTA . :. . .:. :.:::::::::..: .:..::..: : :.:.: .. .::.:: NP_001 HNLMRRSTVSLLDTYQKCGLKRKSEEIEN-TSSVQIIEEH---PPMIQNNASG-ATVATA 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 TTG---SKQNCTTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVA ::. ::.. ...::::::::::::::: ::::::.::::::::::::::::::::::: NP_001 TTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVA 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB7 IKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYD :::::::::::::::::::::::::::.::.::::::::::::.:::::::::::::::: NP_001 IKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQNLYD 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 FLKQNKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVID ::::::::::::: :::.:::::::: :::::::::::::::::::::: :::::::::: NP_001 FLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVID 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB7 FGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALE :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::: : NP_001 FGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASE 350 360 370 380 390 400 410 420 430 440 450 460 pF1KB7 YDQIRYISQTQGLPGEQLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEAR ::::::::::::::.: ::..:::.:::: ..:: . ::::: ..::::::.:::::: NP_001 YDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPYPLWRLKTPDDHEAETGIKSKEAR 410 420 430 440 450 460 470 480 490 500 510 520 pF1KB7 KYIFNSLDDVAHVNTVMDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPF ::::: :::.:.:: . ::::::.:.::::::::..:::::: :::: :::: ::::::: NP_001 KYIFNCLDDMAQVNMTTDLEGSDMLVEKADRREFIDLLKKMLTIDADKRITPIETLNHPF 470 480 490 500 510 520 530 540 550 560 570 580 pF1KB7 VNMKHLLDFPHSNHVKSCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFT- :.: ::::::::.::::::. :.::: ..: :: :..:: .. :: :....:: .:. NP_001 VTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAPSTSTNLTMTFNN 530 540 550 560 570 580 590 600 610 620 630 640 pF1KB7 KIGTLRSQALTTSAHSVVHHGIPLQAGTAQFGCG--DAFQQTLIICPPAIQGIPATHGKP .. :...: ..: .:.....:::.::::. :. : :::.::.:::..::. :. .: NP_001 QLTTVHNQPSAASMAAVAQRSMPLQTGTAQI-CARPDPFQQALIVCPPGFQGLQASPSKH 590 600 610 620 630 640 650 660 670 680 690 pF1KB7 TSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQ-TWSGRTQQMLVP-AWQQVTPLAPATT- ..::.:..:.::.:::::..:::::.::.:.: .: . :::.:.: ::::.: .: :. NP_001 AGYSVRMENAVPIVTQAPGAQPLQIQPGLLAQQAWPSGTQQILLPPAWQQLTGVATHTSV 650 660 670 680 690 700 700 710 720 730 740 750 pF1KB7 ---TLTSESVAGSHRLGDWGKMISCSNHYNSVMPQP-LLTNQITLSAPQPVSVGIAHVVW :. :..::...:.:: . . ..::: .: :: :::...:: : ::..::.:::. NP_001 QHATVIPETMAGTQQLADWRNTHAHGSHYNPIMQQPALLTGHVTLPAAQPLNVGVAHVMR 710 720 730 740 750 760 760 770 780 790 800 810 pF1KB7 PQPATT---KKNKQCQNRGILVKLMEWEPGREEINAFSWSNSLQNTNIPHSAFISPKIIN ::..: .:.:: :. :. : . . :.. . :. ..... :. :.. . NP_001 QQPTSTTSSRKSKQHQSSVRNVSTCEVS-SSQAISSPQRSKRVKENTPPRCAMVHSSPAC 770 780 790 800 810 820 820 830 840 850 860 870 pF1KB7 GKDVEEVSCIETQDNQNSEGEARNCCETSIRQDSDSSVSDKQRQTIIIADSPSPAVSVIT . .: .: . :.. ..:.. ..:::::.: :.:::.::::: NP_001 STSV---TC--------GWGDV-----------ASSTTRERQRQTIVIPDTPSPTVSVIT 830 840 850 860 880 890 900 910 920 930 pF1KB7 ISSDTDEEETSQRHSLRECKGSLDCEACQSTLNIDRMCSLSSPDSTLSTSSSGQSSPSPC ::::::::: :.:. : ::.: NP_001 ISSDTDEEEE-QKHA---------------------------PTSTVSK----------- 870 880 940 950 960 970 980 990 pF1KB7 KRPNSMSDEEQESSCDTVDGSPTSDSSGHDSPFAESTFVEDTHENT-ELVSSADTETKPA .: : .: : :: :: ::::.. ::.. . . .. :. . .: ... NP_001 QRKNVIS-------CVTVHDSPYSDSSSNTSPYSVQQRAGHNNANAFDTKGSLENHCTGN 890 900 910 920 930 1000 1010 1020 1030 pF1KB7 VCSVVVPPVELENG-----------LNADEHMANTDSICQPLIKGRSAPGRLNQPSAVGT ...:::.. . . .:...: .. : . . . :. . .. .:. NP_001 PRTIIVPPLKTQASEVLVECDSLVPVNTSHHSSSYKSKSSSNVTSTSGHSSGSSSGAITY 940 950 960 970 980 990 1040 1050 1060 1070 1080 1090 pF1KB7 RQQKLTSAFQQQH-LNFSQVQHFGSGHQEWNGNFGHRRQQAYIPTSVTSNPFTLSHGSPN :::. ::::. ::.::.:. : . . .:::::::: .... :... :.::. NP_001 RQQRPGPHFQQQQPLNLSQAQQ----HITTDRTGSHRRQQAYITPTMAQAPYSFPHNSPS 1000 1010 1020 1030 1040 1050 1100 1110 1120 1130 1140 1150 pF1KB7 HTAVHAHLAGNT---HLGGQPTLLPYPSSATLSSAAPVAHLLASPCTSRPMLQHPTYNIS : .:: :::. . :: :: : : . :.:.:.. ::::.:: ..: .:: .: NP_001 HGTVHPHLAAAAAAAHLPTQPHLYTYTAPAALGSTGTVAHLVASQGSARHTVQHTAY--- 1060 1070 1080 1090 1100 1160 1170 1180 1190 1200 1210 pF1KB7 HPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPA---YTGFPLSPTKLSQY :..:::::::...::.::::::: .:: : ..::.:::: :::.::::.:..:: NP_001 -PASIVHQVPVSMGPRVLPSPTIHPSQYPAQFAHQTYISASPASTVYTGYPLSPAKVNQY 1110 1120 1130 1140 1150 1160 pF1KB7 PYM ::. NP_001 PYI 1170 >>XP_011514381 (OMIM: 606868) PREDICTED: homeodomain-int (1350 aa) initn: 3442 init1: 2298 opt: 3002 Z-score: 1165.7 bits: 227.9 E(85289): 3.4e-58 Smith-Waterman score: 3754; 51.5% identity (73.8% similar) in 1256 aa overlap (1-1215:187-1350) 10 20 30 pF1KB7 MASQVLVYPPYVYQTQSSAFCSVKKLKVEP :::.: :. :.. ::::::::::::.:: XP_011 LQEATLENKCQVLKRLNIESPPDLAVPLPGMASHVQVFSPHTL--QSSAFCSVKKLKIEP 160 170 180 190 200 210 40 50 60 70 80 pF1KB7 SSC--VFQERNYPRTYVNGRNFGNSHPPTKGSAFQTKIPFNRPRGHNFSLQ-TSAVVLKN :: . .. ..: ...:. :.: : .. .:..: : :: ...:. . XP_011 SSNWDMTGYGSHSKVYSQSKNIPLSQPAT--TTVSTSLPVPNP-----SLPYEQTIVFPG 220 230 240 250 260 90 100 110 120 130 140 pF1KB7 TAGATKVIAAQAQQAHVQA---PQIGAWRNRLHFLEGPQRCGLKRKSEELDNHSSAMQIV ..: : .:.. .. :. :. :. . .:. :.:::::::::..: .:..::. XP_011 STGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQKCGLKRKSEEIEN-TSSVQII 270 280 290 300 310 320 150 160 170 180 190 200 pF1KB7 DELSILPAMLQTNMGNPVTVVTATTG---SKQNCTTGEGDYQLVQHEVLCSMKNTYEVLD .: : :.:.: .. .::.::::. ::.. ...::::::::::::::: ::::::. XP_011 EEH---PPMIQNNASG-ATVATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLE 330 340 350 360 370 380 210 220 230 240 250 260 pF1KB7 FLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRA ::::::::::::::::::::::::::::::::::::::::::::::::::.::.:::::: XP_011 FLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRA 390 400 410 420 430 440 270 280 290 300 310 320 pF1KB7 YECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPILQQVATALKKLKSLGLIHA ::::::.::::::::::::::::::::::::::::: :::.:::::::: :::::::::: XP_011 YECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHA 450 460 470 480 490 500 330 340 350 360 370 380 pF1KB7 DLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAID :::::::::::: :::::::::::::::::::.::::::::::::::::::::::::::: XP_011 DLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAID 510 520 530 540 550 560 390 400 410 420 430 440 pF1KB7 MWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCKETDMSH ::::::::::::::::::::: :::::::::::::::.: ::..:::.:::: ..:: . XP_011 MWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPY 570 580 590 600 610 620 450 460 470 480 490 500 pF1KB7 SGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTVMDLEGSDLLAEKADRREFVSL ::::: ..::::::.::::::::::: :::.:.:: . ::::::.:.::::::::..: XP_011 PLWRLKTPDDHEAETGIKSKEARKYIFNCLDDMAQVNMTTDLEGSDMLVEKADRREFIDL 630 640 650 660 670 680 510 520 530 540 550 560 pF1KB7 LKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVKSCFHIMDICKSHLNSCDTNNH ::::: :::: :::: ::::::::.: ::::::::.::::::. :.::: ..: :: :. XP_011 LKKMLTIDADKRITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQ 690 700 710 720 730 740 570 580 590 600 610 pF1KB7 NKTSLLRPVASSSTATLTANFT-KIGTLRSQALTTSAHSVVHHGIPLQAGTAQFGCG--D .:: .. :: :....:: .:. .. :...: ..: .:.....:::.::::. :. : XP_011 SKTPFITHVAPSTSTNLTMTFNNQLTTVHNQPSAASMAAVAQRSMPLQTGTAQI-CARPD 750 760 770 780 790 800 620 630 640 650 660 670 pF1KB7 AFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQ-TWSG :::.::.:::..::. :. .: ..::.:..:.::.:::::..:::::.::.:.: .: . XP_011 PFQQALIVCPPGFQGLQASPSKHAGYSVRMENAVPIVTQAPGAQPLQIQPGLLAQQAWPS 810 820 830 840 850 860 680 690 700 710 720 730 pF1KB7 RTQQMLVP-AWQQVTPLAPATT----TLTSESVAGSHRLGDWGKMISCSNHYNSVMPQP- :::.:.: ::::.: .: :. :. :..::...:.:: . . ..::: .: :: XP_011 GTQQILLPPAWQQLTGVATHTSVQHATVIPETMAGTQQLADWRNTHAHGSHYNPIMQQPA 870 880 890 900 910 920 740 750 760 770 780 pF1KB7 LLTNQITLSAPQPVSVGIAHVVWPQPATT---KKNKQCQNRGILVKLMEWEPGREEINAF :::...:: : ::..::.:::. ::..: .:.:: :. :. : . . :.. XP_011 LLTGHVTLPAAQPLNVGVAHVMRQQPTSTTSSRKSKQHQSSVRNVSTCEVS-SSQAISSP 930 940 950 960 970 980 790 800 810 820 830 840 pF1KB7 SWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETSIRQDSDSS . :. ..... :. :.. . . .: .: . :.. ..:. XP_011 QRSKRVKENTPPRCAMVHSSPACSTSV---TC--------GWGDV-----------ASST 990 1000 1010 850 860 870 880 890 900 pF1KB7 VSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQSTLNIDRM . ..:::::.: :.:::.:::::::::::::: :.:. XP_011 TRERQRQTIVIPDTPSPTVSVITISSDTDEEEE-QKHA---------------------- 1020 1030 1040 1050 910 920 930 940 950 960 pF1KB7 CSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGHDSPFAEST : ::.: .: : .: : :: :: ::::.. ::.. . XP_011 -----PTSTVSK-----------QRKNVIS-------CVTVHDSPYSDSSSNTSPYSVQQ 1060 1070 1080 1090 970 980 990 1000 1010 pF1KB7 FVEDTHENT-ELVSSADTETKPAVCSVVVPPVELENG-----------LNADEHMANTDS . .. :. . .: ... ...:::.. . . .:...: .. : XP_011 RAGHNNANAFDTKGSLENHCTGNPRTIIVPPLKTQASEVLVECDSLVPVNTSHHSSSYKS 1100 1110 1120 1130 1140 1150 1020 1030 1040 1050 1060 1070 pF1KB7 ICQPLIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQH-LNFSQVQHFGSGHQEWNGNFGHR . . . :. . .. .:. :::. ::::. ::.::.:. : . . .:: XP_011 KSSSNVTSTSGHSSGSSSGAITYRQQRPGPHFQQQQPLNLSQAQQ----HITTDRTGSHR 1160 1170 1180 1190 1200 1080 1090 1100 1110 1120 1130 pF1KB7 RQQAYIPTSVTSNPFTLSHGSPNHTAVHAHLAGNT---HLGGQPTLLPYPSSATLSSAAP :::::: .... :... :.::.: .:: :::. . :: :: : : . :.:.:.. XP_011 RQQAYITPTMAQAPYSFPHNSPSHGTVHPHLAAAAAAAHLPTQPHLYTYTAPAALGSTGT 1210 1220 1230 1240 1250 1260 1140 1150 1160 1170 1180 1190 pF1KB7 VAHLLASPCTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSY ::::.:: ..: .:: .: :..:::::::...::.::::::: .:: : ..: XP_011 VAHLVASQGSARHTVQHTAY----PASIVHQVPVSMGPRVLPSPTIHPSQYPAQFAHQTY 1270 1280 1290 1300 1310 1320 1200 1210 pF1KB7 IAASPA---YTGFPLSPTKLSQYPYM :.:::: :::.::::.:..::::. XP_011 ISASPASTVYTGYPLSPAKVNQYPYI 1330 1340 1350 1215 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:41:03 2016 done: Sat Nov 5 08:41:05 2016 Total Scan time: 15.190 Total Display time: 0.590 Function used was FASTA [36.3.4 Apr, 2011]