FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7327, 838 aa 1>>>pF1KB7327 838 - 838 aa - 838 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3017+/-0.000589; mu= 6.6737+/- 0.036 mean_var=196.6925+/-39.057, 0's: 0 Z-trim(112.9): 254 B-trim: 0 in 0/55 Lambda= 0.091449 statistics sampled from 21819 (22073) to 21819 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.259), width: 16 Scan time: 9.450 The best scores are: opt bits E(85289) NP_060533 (OMIM: 603946,616911) lymphoid-specific ( 838) 5499 739.5 1.5e-212 NP_001275997 (OMIM: 603946,616911) lymphoid-specif ( 822) 5389 724.9 3.5e-208 NP_001276000 (OMIM: 603946,616911) lymphoid-specif ( 714) 4720 636.6 1.2e-181 NP_001276002 (OMIM: 603946,616911) lymphoid-specif ( 700) 4593 619.9 1.3e-176 NP_001275998 (OMIM: 603946,616911) lymphoid-specif ( 806) 3233 440.5 1.5e-122 NP_001276003 (OMIM: 603946,616911) lymphoid-specif ( 477) 3100 422.7 1.9e-117 NP_001275996 (OMIM: 603946,616911) lymphoid-specif ( 884) 2934 401.1 1.2e-110 NP_001276004 (OMIM: 603946,616911) lymphoid-specif ( 432) 2782 380.8 7.4e-105 NP_001275999 (OMIM: 603946,616911) lymphoid-specif ( 740) 2580 354.3 1.2e-96 NP_001276001 (OMIM: 603946,616911) lymphoid-specif ( 708) 2569 352.8 3.1e-96 XP_011519987 (OMIM: 610169) PREDICTED: DNA helicas (1209) 786 117.8 3e-25 XP_016885240 (OMIM: 300012) PREDICTED: probable gl (1036) 784 117.5 3.2e-25 XP_006724845 (OMIM: 300012) PREDICTED: probable gl (1042) 784 117.5 3.3e-25 XP_016885239 (OMIM: 300012) PREDICTED: probable gl (1042) 784 117.5 3.3e-25 NP_001269804 (OMIM: 300012) probable global transc (1058) 784 117.5 3.3e-25 NP_003592 (OMIM: 603375) SWI/SNF-related matrix-as (1052) 770 115.6 1.2e-24 XP_011541414 (OMIM: 602118) PREDICTED: chromodomai (1552) 694 105.7 1.7e-21 XP_005271924 (OMIM: 602118) PREDICTED: chromodomai (1710) 694 105.8 1.8e-21 NP_001261 (OMIM: 602118) chromodomain-helicase-DNA (1710) 694 105.8 1.8e-21 XP_005271923 (OMIM: 602118) PREDICTED: chromodomai (1798) 694 105.8 1.8e-21 NP_001262 (OMIM: 602119,615369) chromodomain-helic (1828) 694 105.8 1.9e-21 NP_001241878 (OMIM: 136000,612761) SWI/SNF-related ( 596) 674 102.8 5e-21 NP_064544 (OMIM: 136000,612761) SWI/SNF-related ma (1026) 674 102.9 7.5e-21 XP_016863952 (OMIM: 136000,612761) PREDICTED: SWI/ (1026) 674 102.9 7.5e-21 NP_001121901 (OMIM: 136000,612761) SWI/SNF-related (1028) 674 102.9 7.5e-21 NP_001121902 (OMIM: 136000,612761) SWI/SNF-related (1028) 674 102.9 7.5e-21 NP_078844 (OMIM: 613039) chromodomain-helicase-DNA ( 784) 652 99.9 4.6e-20 XP_006711702 (OMIM: 613039) PREDICTED: chromodomai ( 784) 652 99.9 4.6e-20 NP_001243265 (OMIM: 613039) chromodomain-helicase- ( 797) 652 100.0 4.6e-20 XP_016858348 (OMIM: 613039) PREDICTED: chromodomai ( 825) 652 100.0 4.8e-20 XP_016858347 (OMIM: 613039) PREDICTED: chromodomai ( 825) 652 100.0 4.8e-20 NP_004275 (OMIM: 613039) chromodomain-helicase-DNA ( 897) 652 100.0 5.1e-20 NP_001243267 (OMIM: 613039) chromodomain-helicase- ( 693) 649 99.5 5.5e-20 XP_016858349 (OMIM: 613039) PREDICTED: chromodomai ( 616) 648 99.3 5.5e-20 NP_001243266 (OMIM: 613039) chromodomain-helicase- ( 616) 648 99.3 5.5e-20 XP_016874223 (OMIM: 603277,617159) PREDICTED: chro (1892) 636 98.1 3.9e-19 XP_016874222 (OMIM: 603277,617159) PREDICTED: chro (1893) 636 98.1 3.9e-19 XP_016874221 (OMIM: 603277,617159) PREDICTED: chro (1895) 636 98.1 3.9e-19 XP_016874220 (OMIM: 603277,617159) PREDICTED: chro (1899) 636 98.1 3.9e-19 XP_016874219 (OMIM: 603277,617159) PREDICTED: chro (1900) 636 98.1 3.9e-19 XP_006719025 (OMIM: 603277,617159) PREDICTED: chro (1902) 636 98.1 3.9e-19 XP_005253725 (OMIM: 603277,617159) PREDICTED: chro (1905) 636 98.1 3.9e-19 NP_001284482 (OMIM: 603277,617159) chromodomain-he (1905) 636 98.1 3.9e-19 XP_016874218 (OMIM: 603277,617159) PREDICTED: chro (1906) 636 98.1 3.9e-19 XP_006719024 (OMIM: 603277,617159) PREDICTED: chro (1908) 636 98.1 3.9e-19 XP_016874217 (OMIM: 603277,617159) PREDICTED: chro (1911) 636 98.1 3.9e-19 NP_001264 (OMIM: 603277,617159) chromodomain-helic (1912) 636 98.1 3.9e-19 XP_016874216 (OMIM: 603277,617159) PREDICTED: chro (1912) 636 98.1 3.9e-19 XP_016874215 (OMIM: 603277,617159) PREDICTED: chro (1913) 636 98.1 3.9e-19 XP_016874214 (OMIM: 603277,617159) PREDICTED: chro (1914) 636 98.1 3.9e-19 >>NP_060533 (OMIM: 603946,616911) lymphoid-specific heli (838 aa) initn: 5499 init1: 5499 opt: 5499 Z-score: 3936.9 bits: 739.5 E(85289): 1.5e-212 Smith-Waterman score: 5499; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838) 10 20 30 40 50 60 pF1KB7 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY 730 740 750 760 770 780 790 800 810 820 830 pF1KB7 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF 790 800 810 820 830 >>NP_001275997 (OMIM: 603946,616911) lymphoid-specific h (822 aa) initn: 5389 init1: 5389 opt: 5389 Z-score: 3858.6 bits: 724.9 E(85289): 3.5e-208 Smith-Waterman score: 5389; 100.0% identity (100.0% similar) in 822 aa overlap (17-838:1-822) 10 20 30 40 50 60 pF1KB7 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES :::::::::::::::::::::::::::::::::::::::::::: NP_001 MVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES 10 20 30 40 70 80 90 100 110 120 pF1KB7 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB7 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB7 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB7 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB7 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB7 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB7 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY 650 660 670 680 690 700 730 740 750 760 770 780 pF1KB7 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY 710 720 730 740 750 760 790 800 810 820 830 pF1KB7 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF 770 780 790 800 810 820 >>NP_001276000 (OMIM: 603946,616911) lymphoid-specific h (714 aa) initn: 4720 init1: 4720 opt: 4720 Z-score: 3382.4 bits: 636.6 E(85289): 1.2e-181 Smith-Waterman score: 4720; 100.0% identity (100.0% similar) in 714 aa overlap (125-838:1-714) 100 110 120 130 140 150 pF1KB7 KKKEKLERKKESLKVKKGKNSIDASEEKPVMRKKRGREDESYNISEVMSKEEILSVAKKN :::::::::::::::::::::::::::::: NP_001 MRKKRGREDESYNISEVMSKEEILSVAKKN 10 20 30 160 170 180 190 200 210 pF1KB7 KKENEDENSSSTNLCVEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKENEDENSSSTNLCVEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQ 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB7 PKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPF 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB7 LVCGPLSTLPNWMAEFKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVCGPLSTLPNWMAEFKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFE 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB7 IAMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELW 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB7 SLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKS 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB7 DVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRK 340 350 360 370 380 390 520 530 540 550 560 570 pF1KB7 SINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHP 400 410 420 430 440 450 580 590 600 610 620 630 pF1KB7 YLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDY 460 470 480 490 500 510 640 650 660 670 680 690 pF1KB7 CHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDS 520 530 540 550 560 570 700 710 720 730 740 750 pF1KB7 DWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKG 580 590 600 610 620 630 760 770 780 790 800 810 pF1KB7 GQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASG 640 650 660 670 680 690 820 830 pF1KB7 PIKEKMGIFKILENSEDSSPECLF :::::::::::::::::::::::: NP_001 PIKEKMGIFKILENSEDSSPECLF 700 710 >>NP_001276002 (OMIM: 603946,616911) lymphoid-specific h (700 aa) initn: 4593 init1: 4593 opt: 4593 Z-score: 3291.9 bits: 619.9 E(85289): 1.3e-176 Smith-Waterman score: 4593; 99.3% identity (99.7% similar) in 699 aa overlap (140-838:2-700) 110 120 130 140 150 160 pF1KB7 KKGKNSIDASEEKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLC .: ..:::::::::::::::::::::::: NP_001 MQVKRSQEILSVAKKNKKENEDENSSSTNLC 10 20 30 170 180 190 200 210 220 pF1KB7 VEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVE 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB7 GMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAE 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB7 FKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWK 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB7 YLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLK 220 230 240 250 260 270 410 420 430 440 450 460 pF1KB7 SFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVY 280 290 300 310 320 330 470 480 490 500 510 520 pF1KB7 APLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELE 340 350 360 370 380 390 530 540 550 560 570 580 pF1KB7 KLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFK 400 410 420 430 440 450 590 600 610 620 630 640 pF1KB7 IDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSM 460 470 480 490 500 510 650 660 670 680 690 700 pF1KB7 SYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCH 520 530 540 550 560 570 710 720 730 740 750 760 pF1KB7 RIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPK 580 590 600 610 620 630 770 780 790 800 810 820 pF1KB7 ELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENS 640 650 660 670 680 690 830 pF1KB7 EDSSPECLF ::::::::: NP_001 EDSSPECLF 700 >>NP_001275998 (OMIM: 603946,616911) lymphoid-specific h (806 aa) initn: 5282 init1: 3232 opt: 3233 Z-score: 2321.4 bits: 440.5 E(85289): 1.5e-122 Smith-Waterman score: 5222; 96.2% identity (96.2% similar) in 838 aa overlap (1-838:1-806) 10 20 30 40 50 60 pF1KB7 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK :::::::::::: :::::::::::::::: NP_001 LYHGTQEERQKL--------------------------------HCYWKYLIVDEGHRIK 310 320 370 380 390 400 410 420 pF1KB7 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB7 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB7 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB7 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK 510 520 530 540 550 560 610 620 630 640 650 660 pF1KB7 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS 570 580 590 600 610 620 670 680 690 700 710 720 pF1KB7 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY 630 640 650 660 670 680 730 740 750 760 770 780 pF1KB7 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY 690 700 710 720 730 740 790 800 810 820 830 pF1KB7 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF 750 760 770 780 790 800 >>NP_001276003 (OMIM: 603946,616911) lymphoid-specific h (477 aa) initn: 3100 init1: 3100 opt: 3100 Z-score: 2229.7 bits: 422.7 E(85289): 1.9e-117 Smith-Waterman score: 3100; 100.0% identity (100.0% similar) in 477 aa overlap (362-838:1-477) 340 350 360 370 380 390 pF1KB7 SFEIAMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLS :::::::::::::::::::::::::::::: NP_001 MKCRLIRELKRFNADNKLLLTGTPLQNNLS 10 20 30 400 410 420 430 440 450 pF1KB7 ELWSLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELWSLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRR 40 50 60 70 80 90 460 470 480 490 500 510 pF1KB7 LKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRR 100 110 120 130 140 150 520 530 540 550 560 570 pF1KB7 TRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCC 160 170 180 190 200 210 580 590 600 610 620 630 pF1KB7 NHPYLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NHPYLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDIL 220 230 240 250 260 270 640 650 660 670 680 690 pF1KB7 MDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVII 280 290 300 310 320 330 700 710 720 730 740 750 pF1KB7 YDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNH 340 350 360 370 380 390 760 770 780 790 800 810 pF1KB7 FKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMN 400 410 420 430 440 450 820 830 pF1KB7 ASGPIKEKMGIFKILENSEDSSPECLF ::::::::::::::::::::::::::: NP_001 ASGPIKEKMGIFKILENSEDSSPECLF 460 470 >>NP_001275996 (OMIM: 603946,616911) lymphoid-specific h (884 aa) initn: 2932 init1: 2932 opt: 2934 Z-score: 2107.6 bits: 401.1 E(85289): 1.2e-110 Smith-Waterman score: 5303; 94.7% identity (94.7% similar) in 870 aa overlap (1-824:1-870) 10 20 30 40 50 60 pF1KB7 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL 370 380 390 400 410 420 430 440 pF1KB7 SETAEDIIAKEREQNVLHMLHQ-------------------------------------- :::::::::::::::::::::: NP_001 SETAEDIIAKEREQNVLHMLHQERIPRMYVSEFTDEGFFEGKLPSRKDLYDIRPYENTYL 430 440 450 460 470 480 450 460 470 480 490 pF1KB7 --------ILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGS :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKLHTNFEILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGS 490 500 510 520 530 540 500 510 520 530 540 550 pF1KB7 SEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVES 550 560 570 580 590 600 560 570 580 590 600 610 pF1KB7 EVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKR 610 620 630 640 650 660 620 630 640 650 660 670 pF1KB7 GHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVST 670 680 690 700 710 720 680 690 700 710 720 730 pF1KB7 RAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVE 730 740 750 760 770 780 740 750 760 770 780 790 pF1KB7 RAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISD 790 800 810 820 830 840 800 810 820 830 pF1KB7 KDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF :::::::::::::::::::::::::::::: NP_001 KDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF 850 860 870 880 >>NP_001276004 (OMIM: 603946,616911) lymphoid-specific h (432 aa) initn: 2782 init1: 2782 opt: 2782 Z-score: 2003.5 bits: 380.8 E(85289): 7.4e-105 Smith-Waterman score: 2782; 100.0% identity (100.0% similar) in 429 aa overlap (410-838:4-432) 380 390 400 410 420 430 pF1KB7 LLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHM :::::::::::::::::::::::::::::: NP_001 MRYSFESWFDITSLSETAEDIIAKEREQNVLHM 10 20 30 440 450 460 470 480 490 pF1KB7 LHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKET 40 50 60 70 80 90 500 510 520 530 540 550 pF1KB7 IELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLK 100 110 120 130 140 150 560 570 580 590 600 610 pF1KB7 LQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVL 160 170 180 190 200 210 620 630 640 650 660 670 pF1KB7 LFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVSTRAGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVSTRAGGL 220 230 240 250 260 270 680 690 700 710 720 730 pF1KB7 GINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAK 280 290 300 310 320 330 740 750 760 770 780 790 pF1KB7 RKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLEL 340 350 360 370 380 390 800 810 820 830 pF1KB7 LLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF ::::::::::::::::::::::::::::::::::::::: NP_001 LLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF 400 410 420 430 >>NP_001275999 (OMIM: 603946,616911) lymphoid-specific h (740 aa) initn: 2576 init1: 2576 opt: 2580 Z-score: 1856.3 bits: 354.3 E(85289): 1.2e-96 Smith-Waterman score: 4630; 88.3% identity (88.3% similar) in 838 aa overlap (1-838:1-740) 10 20 30 40 50 60 pF1KB7 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK :::::::::::::::::::::::::::::::::::::::::::: NP_001 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQ---------------- 310 320 330 340 370 380 390 400 410 420 pF1KB7 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL NP_001 ------------------------------------------------------------ 430 440 450 460 470 480 pF1KB7 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY :::::::::::::::::::::::::::::::::::::: NP_001 ----------------------ILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY 350 360 370 380 490 500 510 520 530 540 pF1KB7 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD 390 400 410 420 430 440 550 560 570 580 590 600 pF1KB7 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK 450 460 470 480 490 500 610 620 630 640 650 660 pF1KB7 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS 510 520 530 540 550 560 670 680 690 700 710 720 pF1KB7 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY 570 580 590 600 610 620 730 740 750 760 770 780 pF1KB7 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY 630 640 650 660 670 680 790 800 810 820 830 pF1KB7 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF 690 700 710 720 730 740 >>NP_001276001 (OMIM: 603946,616911) lymphoid-specific h (708 aa) initn: 2569 init1: 2569 opt: 2569 Z-score: 1848.7 bits: 352.8 E(85289): 3.1e-96 Smith-Waterman score: 4363; 84.5% identity (84.5% similar) in 838 aa overlap (1-838:1-708) 10 20 30 40 50 60 pF1KB7 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK :::::::::::: NP_001 LYHGTQEERQKL------------------------------------------------ 310 370 380 390 400 410 420 pF1KB7 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL NP_001 ------------------------------------------------------------ 430 440 450 460 470 480 pF1KB7 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY :::::::::::::::::::::::::::::::::::::: NP_001 ----------------------ILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY 320 330 340 350 490 500 510 520 530 540 pF1KB7 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD 360 370 380 390 400 410 550 560 570 580 590 600 pF1KB7 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK 420 430 440 450 460 470 610 620 630 640 650 660 pF1KB7 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS 480 490 500 510 520 530 670 680 690 700 710 720 pF1KB7 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY 540 550 560 570 580 590 730 740 750 760 770 780 pF1KB7 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY 600 610 620 630 640 650 790 800 810 820 830 pF1KB7 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF 660 670 680 690 700 838 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:41:46 2016 done: Sat Nov 5 08:41:47 2016 Total Scan time: 9.450 Total Display time: 0.200 Function used was FASTA [36.3.4 Apr, 2011]