FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7335, 1020 aa 1>>>pF1KB7335 1020 - 1020 aa - 1020 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8343+/-0.000332; mu= 20.0961+/- 0.021 mean_var=91.6842+/-18.777, 0's: 0 Z-trim(117.0): 18 B-trim: 139 in 1/49 Lambda= 0.133945 statistics sampled from 28581 (28599) to 28581 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.335), width: 16 Scan time: 15.520 The best scores are: opt bits E(85289) NP_056099 (OMIM: 615463,615476) protein SZT2 [Homo (3375) 6870 1338.7 0 XP_006710564 (OMIM: 615463,615476) PREDICTED: prot (3432) 6863 1337.3 0 XP_016856308 (OMIM: 615463,615476) PREDICTED: prot (3402) 6801 1325.3 0 XP_005270743 (OMIM: 615463,615476) PREDICTED: prot (3453) 6801 1325.3 0 XP_011539408 (OMIM: 615463,615476) PREDICTED: prot (3413) 6741 1313.7 0 XP_016856309 (OMIM: 615463,615476) PREDICTED: prot (3396) 5750 1122.2 0 XP_011539409 (OMIM: 615463,615476) PREDICTED: prot (3280) 5747 1121.6 0 XP_016856310 (OMIM: 615463,615476) PREDICTED: prot (2996) 3980 780.1 0 >>NP_056099 (OMIM: 615463,615476) protein SZT2 [Homo sap (3375 aa) initn: 6870 init1: 6870 opt: 6870 Z-score: 7162.8 bits: 1338.7 E(85289): 0 Smith-Waterman score: 6870; 99.8% identity (99.9% similar) in 1018 aa overlap (1-1018:1-1018) 10 20 30 40 50 60 pF1KB7 MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLSHLHQTVQATPQEMLLQSEQELEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLSHLHQTVQATPQEMLLQSEQELEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDLSPSTGIVDDSTGEILFDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDLSPSTGIVDDSTGEILFDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSQRE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSGDLLGRKVGVSMVTADLGLVSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSGDLLGRKVGVSMVTADLGLVSM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 IRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 DCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLTVYHRAFLLYSFLRSGEALNPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLTVYHRAFLLYSFLRSGEALNPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 YYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 YYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 GGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRVEVTMEGGYDILHDVSCALRQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRVEVTMEGGYDILHDVSCALRQP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 IRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEHFTLPDSTKSGVPLFYIPPGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEHFTLPDSTKSGVPLFYIPPGST 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 TPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPIPKHLHTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPIPKHLHTPG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 SNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPNSFYMVRIISKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPNSFYMVRIISKAP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 CMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQSKEPTPKVKRKGLGGAGGGSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 CMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQSKEPTPKVKRKGLGGAGGGSSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 SKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 SASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLLSILTEVRLSEGFHFACSGEGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLLSILTEVRLSEGFHFACSGEGI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 INMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 INMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 ELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQALHPRDAACIGSMLSFEYLIQLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQALHPRDAACIGSMLSFEYLIQLC 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 QSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQMFFLLLARAAWGRS ::::::::::::::::::::::::::::::::::::::::::::::::::::::.: : NP_056 QSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQMFFLLLARGAEGPL 970 980 990 1000 1010 1020 NP_056 LGVHGIPKEQAVGSTQATGDSAFTSLSVGLPETLKPLISAQPPQWRCYARLVNPQHVFLT 1030 1040 1050 1060 1070 1080 >>XP_006710564 (OMIM: 615463,615476) PREDICTED: protein (3432 aa) initn: 6860 init1: 6860 opt: 6863 Z-score: 7155.4 bits: 1337.3 E(85289): 0 Smith-Waterman score: 6863; 99.7% identity (99.7% similar) in 1018 aa overlap (1-1018:1-1018) 10 20 30 40 50 60 pF1KB7 MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLSHLHQTVQATPQEMLLQSEQELEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLSHLHQTVQATPQEMLLQSEQELEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDLSPSTGIVDDSTGEILFDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDLSPSTGIVDDSTGEILFDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSQRE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSGDLLGRKVGVSMVTADLGLVSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSGDLLGRKVGVSMVTADLGLVSM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 IRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 DCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLTVYHRAFLLYSFLRSGEALNPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLTVYHRAFLLYSFLRSGEALNPE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 YYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 GGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRVEVTMEGGYDILHDVSCALRQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRVEVTMEGGYDILHDVSCALRQP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 IRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEHFTLPDSTKSGVPLFYIPPGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEHFTLPDSTKSGVPLFYIPPGST 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 TPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPIPKHLHTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPIPKHLHTPG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 SNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPNSFYMVRIISKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPNSFYMVRIISKAP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB7 CMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQSKEPTPKVKRKGLGGAGGGSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQSKEPTPKVKRKGLGGAGGGSSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB7 SKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB7 SASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLLSILTEVRLSEGFHFACSGEGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLLSILTEVRLSEGFHFACSGEGI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB7 INMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 INMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB7 ELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQALHPRDAACIGSMLSFEYLIQLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQALHPRDAACIGSMLSFEYLIQLC 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB7 QSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQMFFLLLARAAWGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_006 QSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQMFFLLLAREPEGVP 970 980 990 1000 1010 1020 XP_006 FAEGSCPANDMVLCLLHSCLGQELSDREIPLTPVDQAAFLSEVLRRTCHVPGAEGPLLGV 1030 1040 1050 1060 1070 1080 >>XP_016856308 (OMIM: 615463,615476) PREDICTED: protein (3402 aa) initn: 6798 init1: 6798 opt: 6801 Z-score: 7090.7 bits: 1325.3 E(85289): 0 Smith-Waterman score: 6811; 97.7% identity (97.7% similar) in 1039 aa overlap (1-1018:1-1039) 10 20 30 pF1KB7 MASERPEPE---------------------VEEAGQVFLLMKKDYRISRNVRLAWFLSHL ::::::::: :::::::::::::::::::::::::::::: XP_016 MASERPEPETTLRVMNFRLKEDSYEDLKLHVEEAGQVFLLMKKDYRISRNVRLAWFLSHL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 HQTVQATPQEMLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HQTVQATPQEMLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 LDLSPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDLSPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSI 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 IGLQSHQVLVQGCLLDPSQREVFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGLQSHQVLVQGCLLDPSQREVFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 DLLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 NQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLT 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB7 VYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADL 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB7 VSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRV 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB7 EVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEH 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB7 FTLPDSTKSGVPLFYIPPGSTTPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTLPDSTKSGVPLFYIPPGSTTPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHM 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB7 HRLVLILEHDTPIPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRLVLILEHDTPIPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLL 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB7 SSAPDQPPNSFYMVRIISKAPCMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSAPDQPPNSFYMVRIISKAPCMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQS 670 680 690 700 710 720 700 710 720 730 740 750 pF1KB7 KEPTPKVKRKGLGGAGGGSSPSKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEPTPKVKRKGLGGAGGGSSPSKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLD 730 740 750 760 770 780 760 770 780 790 800 810 pF1KB7 YRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLL 790 800 810 820 830 840 820 830 840 850 860 870 pF1KB7 SILTEVRLSEGFHFACSGEGIINMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SILTEVRLSEGFHFACSGEGIINMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTST 850 860 870 880 890 900 880 890 900 910 920 930 pF1KB7 KDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQAL 910 920 930 940 950 960 940 950 960 970 980 990 pF1KB7 HPRDAACIGSMLSFEYLIQLCQSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPRDAACIGSMLSFEYLIQLCQSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLL 970 980 990 1000 1010 1020 1000 1010 1020 pF1KB7 PQCQQLQMFFLLLARAAWGRS ::::::::::::::: : XP_016 PQCQQLQMFFLLLAREPEGVPFAEGSCPANDMVLCLLHSCLGQELSDREIPLTPVDQAAF 1030 1040 1050 1060 1070 1080 >>XP_005270743 (OMIM: 615463,615476) PREDICTED: protein (3453 aa) initn: 6798 init1: 6798 opt: 6801 Z-score: 7090.6 bits: 1325.3 E(85289): 0 Smith-Waterman score: 6811; 97.7% identity (97.7% similar) in 1039 aa overlap (1-1018:1-1039) 10 20 30 pF1KB7 MASERPEPE---------------------VEEAGQVFLLMKKDYRISRNVRLAWFLSHL ::::::::: :::::::::::::::::::::::::::::: XP_005 MASERPEPETTLRVMNFRLKEDSYEDLKLHVEEAGQVFLLMKKDYRISRNVRLAWFLSHL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 HQTVQATPQEMLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HQTVQATPQEMLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 LDLSPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDLSPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSI 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 IGLQSHQVLVQGCLLDPSQREVFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGLQSHQVLVQGCLLDPSQREVFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 DLLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 NQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLT 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB7 VYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADL 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB7 VSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRV 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB7 EVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEH 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB7 FTLPDSTKSGVPLFYIPPGSTTPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FTLPDSTKSGVPLFYIPPGSTTPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHM 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB7 HRLVLILEHDTPIPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRLVLILEHDTPIPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLL 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB7 SSAPDQPPNSFYMVRIISKAPCMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSAPDQPPNSFYMVRIISKAPCMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQS 670 680 690 700 710 720 700 710 720 730 740 750 pF1KB7 KEPTPKVKRKGLGGAGGGSSPSKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEPTPKVKRKGLGGAGGGSSPSKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLD 730 740 750 760 770 780 760 770 780 790 800 810 pF1KB7 YRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLL 790 800 810 820 830 840 820 830 840 850 860 870 pF1KB7 SILTEVRLSEGFHFACSGEGIINMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SILTEVRLSEGFHFACSGEGIINMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTST 850 860 870 880 890 900 880 890 900 910 920 930 pF1KB7 KDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQAL 910 920 930 940 950 960 940 950 960 970 980 990 pF1KB7 HPRDAACIGSMLSFEYLIQLCQSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HPRDAACIGSMLSFEYLIQLCQSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLL 970 980 990 1000 1010 1020 1000 1010 1020 pF1KB7 PQCQQLQMFFLLLARAAWGRS ::::::::::::::: : XP_005 PQCQQLQMFFLLLAREPEGVPFAEGSCPANDMVLCLLHSCLGQELSDREIPLTPVDQAAF 1030 1040 1050 1060 1070 1080 >>XP_011539408 (OMIM: 615463,615476) PREDICTED: protein (3413 aa) initn: 6738 init1: 6738 opt: 6741 Z-score: 7028.0 bits: 1313.7 E(85289): 0 Smith-Waterman score: 6741; 99.7% identity (99.7% similar) in 999 aa overlap (20-1018:1-999) 10 20 30 40 50 60 pF1KB7 MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLSHLHQTVQATPQEMLLQSEQELEV ::::::::::::::::::::::::::::::::::::::::: XP_011 MKKDYRISRNVRLAWFLSHLHQTVQATPQEMLLQSEQELEV 10 20 30 40 70 80 90 100 110 120 pF1KB7 LSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDLSPSTGIVDDSTGEILFDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDLSPSTGIVDDSTGEILFDE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 VFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSQRE 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 VFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSGDLLGRKVGVSMVTADLGLVSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSGDLLGRKVGVSMVTADLGLVSM 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 IRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSY 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 DCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLTVYHRAFLLYSFLRSGEALNPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLTVYHRAFLLYSFLRSGEALNPE 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB7 YYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAK 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB7 GGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRVEVTMEGGYDILHDVSCALRQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRVEVTMEGGYDILHDVSCALRQP 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB7 IRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEHFTLPDSTKSGVPLFYIPPGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEHFTLPDSTKSGVPLFYIPPGST 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB7 TPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPIPKHLHTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPIPKHLHTPG 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB7 SNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPNSFYMVRIISKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPNSFYMVRIISKAP 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB7 CMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQSKEPTPKVKRKGLGGAGGGSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQSKEPTPKVKRKGLGGAGGGSSP 650 660 670 680 690 700 730 740 750 760 770 780 pF1KB7 SKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGR 710 720 730 740 750 760 790 800 810 820 830 840 pF1KB7 SASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLLSILTEVRLSEGFHFACSGEGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLLSILTEVRLSEGFHFACSGEGI 770 780 790 800 810 820 850 860 870 880 890 900 pF1KB7 INMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDS 830 840 850 860 870 880 910 920 930 940 950 960 pF1KB7 ELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQALHPRDAACIGSMLSFEYLIQLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQALHPRDAACIGSMLSFEYLIQLC 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KB7 QSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQMFFLLLARAAWGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_011 QSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQMFFLLLAREPEGVP 950 960 970 980 990 1000 XP_011 FAEGSCPANDMVLCLLHSCLGQELSDREIPLTPVDQAAFLSEVLRRTCHVPGAEGPLLGV 1010 1020 1030 1040 1050 1060 >>XP_016856309 (OMIM: 615463,615476) PREDICTED: protein (3396 aa) initn: 5793 init1: 5742 opt: 5750 Z-score: 5993.1 bits: 1122.2 E(85289): 0 Smith-Waterman score: 6299; 92.2% identity (92.2% similar) in 1039 aa overlap (1-1018:1-982) 10 20 30 pF1KB7 MASERPEPE---------------------VEEAGQVFLLMKKDYRISRNVRLAWFLSHL ::::::::: :::::::::::::::::::::::::::::: XP_016 MASERPEPETTLRVMNFRLKEDSYEDLKLHVEEAGQVFLLMKKDYRISRNVRLAWFLSHL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 HQTVQATPQEMLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HQTVQATPQEMLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 LDLSPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSI :::::::::: XP_016 LDLSPSTGIV-------------------------------------------------- 130 160 170 180 190 200 210 pF1KB7 IGLQSHQVLVQGCLLDPSQREVFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSG ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -------VLVQGCLLDPSQREVFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSG 140 150 160 170 180 220 230 240 250 260 270 pF1KB7 DLLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLL 190 200 210 220 230 240 280 290 300 310 320 330 pF1KB7 NQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLT 250 260 270 280 290 300 340 350 360 370 380 390 pF1KB7 VYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADL 310 320 330 340 350 360 400 410 420 430 440 450 pF1KB7 VSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRV 370 380 390 400 410 420 460 470 480 490 500 510 pF1KB7 EVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEH 430 440 450 460 470 480 520 530 540 550 560 570 pF1KB7 FTLPDSTKSGVPLFYIPPGSTTPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTLPDSTKSGVPLFYIPPGSTTPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHM 490 500 510 520 530 540 580 590 600 610 620 630 pF1KB7 HRLVLILEHDTPIPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRLVLILEHDTPIPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLL 550 560 570 580 590 600 640 650 660 670 680 690 pF1KB7 SSAPDQPPNSFYMVRIISKAPCMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSAPDQPPNSFYMVRIISKAPCMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQS 610 620 630 640 650 660 700 710 720 730 740 750 pF1KB7 KEPTPKVKRKGLGGAGGGSSPSKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEPTPKVKRKGLGGAGGGSSPSKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLD 670 680 690 700 710 720 760 770 780 790 800 810 pF1KB7 YRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLL 730 740 750 760 770 780 820 830 840 850 860 870 pF1KB7 SILTEVRLSEGFHFACSGEGIINMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SILTEVRLSEGFHFACSGEGIINMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTST 790 800 810 820 830 840 880 890 900 910 920 930 pF1KB7 KDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQAL 850 860 870 880 890 900 940 950 960 970 980 990 pF1KB7 HPRDAACIGSMLSFEYLIQLCQSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPRDAACIGSMLSFEYLIQLCQSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLL 910 920 930 940 950 960 1000 1010 1020 pF1KB7 PQCQQLQMFFLLLARAAWGRS ::::::::::::::: : XP_016 PQCQQLQMFFLLLAREPEGVPFAEGSCPANDMVLCLLHSCLGQELSDREIPLTPVDQAAF 970 980 990 1000 1010 1020 >>XP_011539409 (OMIM: 615463,615476) PREDICTED: protein (3280 aa) initn: 5744 init1: 5744 opt: 5747 Z-score: 5990.2 bits: 1121.6 E(85289): 0 Smith-Waterman score: 5747; 99.4% identity (99.6% similar) in 854 aa overlap (165-1018:13-866) 140 150 160 170 180 190 pF1KB7 PFRVPGSCIDFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSQREVFLQQIYEQLCLFE ..:::::::::::::::::::::::::::: XP_011 MDFSDRGTSKSKYMVLVQGCLLDPSQREVFLQQIYEQLCLFE 10 20 30 40 200 210 220 230 240 250 pF1KB7 DKVATMLQQQYDPQSQAEDQSPDSGDLLGRKVGVSMVTADLGLVSMIRQGILALQLLPSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKVATMLQQQYDPQSQAEDQSPDSGDLLGRKVGVSMVTADLGLVSMIRQGILALQLLPSN 50 60 70 80 90 100 260 270 280 290 300 310 pF1KB7 SSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMK 110 120 130 140 150 160 320 330 340 350 360 370 pF1KB7 FIAMATFGSYLSTCPEPEPGNLGLTVYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIAMATFGSYLSTCPEPEPGNLGLTVYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHL 170 180 190 200 210 220 380 390 400 410 420 430 pF1KB7 VSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWK 230 240 250 260 270 280 440 450 460 470 480 490 pF1KB7 HNMRIEYVAMAPWPLEPEGPRVTRVEVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNMRIEYVAMAPWPLEPEGPRVTRVEVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFW 290 300 310 320 330 340 500 510 520 530 540 550 pF1KB7 NTLQSINQTDQMLAHLQSFSSVPEHFTLPDSTKSGVPLFYIPPGSTTPVLSLQPSGSDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTLQSINQTDQMLAHLQSFSSVPEHFTLPDSTKSGVPLFYIPPGSTTPVLSLQPSGSDSS 350 360 370 380 390 400 560 570 580 590 600 610 pF1KB7 HAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPIPKHLHTPGSNGRYSTIQCRISH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPIPKHLHTPGSNGRYSTIQCRISH 410 420 430 440 450 460 620 630 640 650 660 670 pF1KB7 SSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPNSFYMVRIISKAPCMVLRLGFPIGTPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPNSFYMVRIISKAPCMVLRLGFPIGTPA 470 480 490 500 510 520 680 690 700 710 720 730 pF1KB7 PARHKIVSGLREEILRLRFPHRVQSKEPTPKVKRKGLGGAGGGSSPSKSPPVLGPQQALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PARHKIVSGLREEILRLRFPHRVQSKEPTPKVKRKGLGGAGGGSSPSKSPPVLGPQQALS 530 540 550 560 570 580 740 750 760 770 780 790 pF1KB7 DRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLY 590 600 610 620 630 640 800 810 820 830 840 850 pF1KB7 HQRWLWSVPSGLAPALPLSAIAQLLSILTEVRLSEGFHFACSGEGIINMVLELPIQNEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQRWLWSVPSGLAPALPLSAIAQLLSILTEVRLSEGFHFACSGEGIINMVLELPIQNEPP 650 660 670 680 690 700 860 870 880 890 900 910 pF1KB7 GQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQY 710 720 730 740 750 760 920 930 940 950 960 970 pF1KB7 GRVGPGPGIWKHLQDLTYSEIPQALHPRDAACIGSMLSFEYLIQLCQSKEWGPLPPEPRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRVGPGPGIWKHLQDLTYSEIPQALHPRDAACIGSMLSFEYLIQLCQSKEWGPLPPEPRV 770 780 790 800 810 820 980 990 1000 1010 1020 pF1KB7 SDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQMFFLLLARAAWGRS :::::::::::::::::::::::::::::::::::::::: : XP_011 SDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQMFFLLLAREPEGVPFAEGSCPANDMVLC 830 840 850 860 870 880 XP_011 LLHSCLGQELSDREIPLTPVDQAAFLSEVLRRTCHVPGAEGPLLGVHGIPKEQAVGSTQA 890 900 910 920 930 940 >>XP_016856310 (OMIM: 615463,615476) PREDICTED: protein (2996 aa) initn: 3977 init1: 3977 opt: 3980 Z-score: 4145.3 bits: 780.1 E(85289): 0 Smith-Waterman score: 3980; 99.5% identity (99.5% similar) in 582 aa overlap (437-1018:1-582) 410 420 430 440 450 460 pF1KB7 LREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRVEVTMEGG :::::::::::::::::::::::::::::: XP_016 MRIEYVAMAPWPLEPEGPRVTRVEVTMEGG 10 20 30 470 480 490 500 510 520 pF1KB7 YDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEHFTLPDST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEHFTLPDST 40 50 60 70 80 90 530 540 550 560 570 580 pF1KB7 KSGVPLFYIPPGSTTPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSGVPLFYIPPGSTTPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLIL 100 110 120 130 140 150 590 600 610 620 630 640 pF1KB7 EHDTPIPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHDTPIPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQP 160 170 180 190 200 210 650 660 670 680 690 700 pF1KB7 PNSFYMVRIISKAPCMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQSKEPTPKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNSFYMVRIISKAPCMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQSKEPTPKV 220 230 240 250 260 270 710 720 730 740 750 760 pF1KB7 KRKGLGGAGGGSSPSKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRKGLGGAGGGSSPSKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLL 280 290 300 310 320 330 770 780 790 800 810 820 pF1KB7 TLEPPGPLPLVSGRSASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLLSILTEVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLEPPGPLPLVSGRSASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLLSILTEVR 340 350 360 370 380 390 830 840 850 860 870 880 pF1KB7 LSEGFHFACSGEGIINMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSEGFHFACSGEGIINMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTD 400 410 420 430 440 450 890 900 910 920 930 940 pF1KB7 DDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQALHPRDAAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQALHPRDAAC 460 470 480 490 500 510 950 960 970 980 990 1000 pF1KB7 IGSMLSFEYLIQLCQSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGSMLSFEYLIQLCQSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQ 520 530 540 550 560 570 1010 1020 pF1KB7 MFFLLLARAAWGRS :::::::: : XP_016 MFFLLLAREPEGVPFAEGSCPANDMVLCLLHSCLGQELSDREIPLTPVDQAAFLSEVLRR 580 590 600 610 620 630 1020 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:47:15 2016 done: Sat Nov 5 08:47:17 2016 Total Scan time: 15.520 Total Display time: 0.330 Function used was FASTA [36.3.4 Apr, 2011]