FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7365, 188 aa 1>>>pF1KB7365 188 - 188 aa - 188 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5215+/-0.000274; mu= 14.1313+/- 0.017 mean_var=100.8801+/-20.042, 0's: 0 Z-trim(120.7): 35 B-trim: 0 in 0/58 Lambda= 0.127694 statistics sampled from 36137 (36178) to 36137 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.424), width: 16 Scan time: 5.500 The best scores are: opt bits E(85289) NP_775494 (OMIM: 300542) protein SSX7 [Homo sapien ( 188) 1296 248.0 6.6e-66 NP_783629 (OMIM: 300192,300813) protein SSX2 isofo ( 188) 1097 211.3 7.2e-55 NP_066294 (OMIM: 300325) protein SSX3 [Homo sapien ( 188) 1088 209.7 2.3e-54 XP_016884919 (OMIM: 300542) PREDICTED: protein SSX ( 223) 1075 207.4 1.4e-53 XP_016885247 (OMIM: 300327) PREDICTED: protein SSX ( 188) 1071 206.6 2e-53 NP_783729 (OMIM: 300327) protein SSX5 isoform b [H ( 188) 1071 206.6 2e-53 XP_011542251 (OMIM: 300327) PREDICTED: protein SSX ( 188) 1071 206.6 2e-53 XP_016885248 (OMIM: 300326) PREDICTED: protein SSX ( 188) 1048 202.3 3.8e-52 NP_005627 (OMIM: 300326) protein SSX4 isoform a [H ( 188) 1048 202.3 3.8e-52 NP_005626 (OMIM: 300813,312820) protein SSX1 [Homo ( 188) 998 193.1 2.2e-49 NP_001265620 (OMIM: 300813,312820) protein SSX1 [H ( 188) 998 193.1 2.2e-49 NP_066295 (OMIM: 300327) protein SSX5 isoform a [H ( 229) 934 181.4 9.1e-46 NP_001265626 (OMIM: 300192,300813) protein SSX2 is ( 214) 883 172.0 5.8e-43 NP_003138 (OMIM: 300192,300813) protein SSX2 isofo ( 223) 883 172.0 6e-43 XP_011542187 (OMIM: 300325) PREDICTED: protein SSX ( 170) 869 169.3 3e-42 XP_016884920 (OMIM: 300542) PREDICTED: protein SSX ( 129) 754 148.0 5.8e-36 NP_783856 (OMIM: 300326) protein SSX4 isoform b [H ( 153) 575 115.1 5.5e-26 NP_001297143 (OMIM: 609760) histone-lysine N-methy ( 894) 226 51.5 4.4e-06 NP_064612 (OMIM: 609760) histone-lysine N-methyltr ( 894) 226 51.5 4.4e-06 XP_011521131 (OMIM: 609759) PREDICTED: probable hi ( 377) 213 48.8 1.2e-05 XP_005256331 (OMIM: 609759) PREDICTED: probable hi ( 492) 213 48.9 1.5e-05 NP_001091643 (OMIM: 609759) probable histone-lysin ( 492) 213 48.9 1.5e-05 XP_011521133 (OMIM: 609759) PREDICTED: probable hi ( 172) 184 43.1 0.00029 >>NP_775494 (OMIM: 300542) protein SSX7 [Homo sapiens] (188 aa) initn: 1296 init1: 1296 opt: 1296 Z-score: 1304.2 bits: 248.0 E(85289): 6.6e-66 Smith-Waterman score: 1296; 100.0% identity (100.0% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSGPKRGKHAWTHRLRERKQLVIYEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSGPKRGKHAWTHRLRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDE :::::::: NP_775 SDPEEDDE >>NP_783629 (OMIM: 300192,300813) protein SSX2 isoform b (188 aa) initn: 1097 init1: 1097 opt: 1097 Z-score: 1106.0 bits: 211.3 E(85289): 7.2e-55 Smith-Waterman score: 1097; 85.6% identity (92.6% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK ::::::::::: .::::::::::.::::::::::.::::::. ::: ::::::::::::: NP_783 MNGDDAFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKASEKIFYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG ::::::::::: : : :.::::.::: :.::::::::::: ::: : :::::::::::: NP_783 LGFKATLPPFMCNKRAEDFQGNDLDNDPNRGNQVERPQMTFGRLQGISPKIMPKKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSGPKRGKHAWTHRLRERKQLVIYEEI :::. :::::: :::::.:::::::.:::::.. ::::::.::::::::::::::::::: NP_783 NDSEEVPEASGPQNDGKELCPPGKPTTSEKIHERSGPKRGEHAWTHRLRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDE :::::::: NP_783 SDPEEDDE >>NP_066294 (OMIM: 300325) protein SSX3 [Homo sapiens] (188 aa) initn: 1088 init1: 1088 opt: 1088 Z-score: 1097.1 bits: 209.7 E(85289): 2.3e-54 Smith-Waterman score: 1088; 85.1% identity (91.5% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK :::::.::::: .::::::::::.::::::::::.:::::: ::: ::::::::::::: NP_066 MNGDDTFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKVSEKIVYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG ::::: :: ::.: .::.:::::::: :.::::.:::::: ::: :::::::::::::: NP_066 LGFKAILPSFMRNKRVTDFQGNDFDNDPNRGNQVQRPQMTFGRLQGIFPKIMPKKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSGPKRGKHAWTHRLRERKQLVIYEEI : :: :::::: :::::.:::::::.:::::: ::::::.::::::::::::::::::: NP_066 NVSKEVPEASGPQNDGKQLCPPGKPTTSEKINMISGPKRGEHAWTHRLRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDE :::::::: NP_066 SDPEEDDE >>XP_016884919 (OMIM: 300542) PREDICTED: protein SSX7 is (223 aa) initn: 1073 init1: 1073 opt: 1075 Z-score: 1083.2 bits: 207.4 E(85289): 1.4e-53 Smith-Waterman score: 1194; 84.1% identity (84.1% similar) in 220 aa overlap (1-185:1-220) 10 20 30 40 50 60 pF1KB7 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG 70 80 90 100 110 120 130 140 150 pF1KB7 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSG------------------------ :::::::::::::::::::::::::::::::::::: XP_016 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSGNREVQEKEERWGIAHRWSSQKTHN 130 140 150 160 170 180 160 170 180 pF1KB7 -----------PKRGKHAWTHRLRERKQLVIYEEISDPEEDDE ::::::::::::::::::::::::::::: XP_016 INRLSLSSSMGPKRGKHAWTHRLRERKQLVIYEEISDPEEDDE 190 200 210 220 >>XP_016885247 (OMIM: 300327) PREDICTED: protein SSX5 is (188 aa) initn: 1071 init1: 1071 opt: 1071 Z-score: 1080.1 bits: 206.6 E(85289): 2e-53 Smith-Waterman score: 1071; 83.0% identity (93.6% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK :::::::.::::.:.:::::.::.:::::::::.:::::::. ::: ::::::::::::: XP_016 MNGDDAFVRRPRVGSQIPEKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG :::::::::::.: ..:.:::::::: :.:::::.::::: ::: ::::: :.:::::: XP_016 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSGPKRGKHAWTHRLRERKQLVIYEEI ::::::::::: ::.::.: : :: .::::.::::::::::::::::.:::::::::::: XP_016 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDE :::.:::: XP_016 SDPQEDDE >>NP_783729 (OMIM: 300327) protein SSX5 isoform b [Homo (188 aa) initn: 1071 init1: 1071 opt: 1071 Z-score: 1080.1 bits: 206.6 E(85289): 2e-53 Smith-Waterman score: 1071; 83.0% identity (93.6% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK :::::::.::::.:.:::::.::.:::::::::.:::::::. ::: ::::::::::::: NP_783 MNGDDAFVRRPRVGSQIPEKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG :::::::::::.: ..:.:::::::: :.:::::.::::: ::: ::::: :.:::::: NP_783 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSGPKRGKHAWTHRLRERKQLVIYEEI ::::::::::: ::.::.: : :: .::::.::::::::::::::::.:::::::::::: NP_783 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDE :::.:::: NP_783 SDPQEDDE >>XP_011542251 (OMIM: 300327) PREDICTED: protein SSX5 is (188 aa) initn: 1071 init1: 1071 opt: 1071 Z-score: 1080.1 bits: 206.6 E(85289): 2e-53 Smith-Waterman score: 1071; 83.0% identity (93.6% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK :::::::.::::.:.:::::.::.:::::::::.:::::::. ::: ::::::::::::: XP_011 MNGDDAFVRRPRVGSQIPEKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG :::::::::::.: ..:.:::::::: :.:::::.::::: ::: ::::: :.:::::: XP_011 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSGPKRGKHAWTHRLRERKQLVIYEEI ::::::::::: ::.::.: : :: .::::.::::::::::::::::.:::::::::::: XP_011 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDE :::.:::: XP_011 SDPQEDDE >>XP_016885248 (OMIM: 300326) PREDICTED: protein SSX4 is (188 aa) initn: 1048 init1: 1048 opt: 1048 Z-score: 1057.2 bits: 202.3 E(85289): 3.8e-52 Smith-Waterman score: 1048; 82.4% identity (90.4% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK :::::::::::: ::: ::..:.:::::::::::::::::: ::: ::::: .::.::: XP_016 MNGDDAFARRPRDDAQISEKLRKAFDDIAKYFSKKEWEKMKSSEKIVYVYMKLNYEVMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG ::::.::::::.. :.:..:::: ::::. :::::::::: :::::::::::::::: XP_016 LGFKVTLPPFMRSKRAADFHGNDFGNDRNHRNQVERPQMTFGSLQRIFPKIMPKKPAEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSGPKRGKHAWTHRLRERKQLVIYEEI : : :::::: :::::.:::::.::: :::::::::::::::::::::::::::.:::: XP_016 NGLKEVPEASGPQNDGKQLCPPGNPSTLEKINKTSGPKRGKHAWTHRLRERKQLVVYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDE :::::::: XP_016 SDPEEDDE >>NP_005627 (OMIM: 300326) protein SSX4 isoform a [Homo (188 aa) initn: 1048 init1: 1048 opt: 1048 Z-score: 1057.2 bits: 202.3 E(85289): 3.8e-52 Smith-Waterman score: 1048; 82.4% identity (90.4% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK :::::::::::: ::: ::..:.:::::::::::::::::: ::: ::::: .::.::: NP_005 MNGDDAFARRPRDDAQISEKLRKAFDDIAKYFSKKEWEKMKSSEKIVYVYMKLNYEVMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG ::::.::::::.. :.:..:::: ::::. :::::::::: :::::::::::::::: NP_005 LGFKVTLPPFMRSKRAADFHGNDFGNDRNHRNQVERPQMTFGSLQRIFPKIMPKKPAEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSGPKRGKHAWTHRLRERKQLVIYEEI : : :::::: :::::.:::::.::: :::::::::::::::::::::::::::.:::: NP_005 NGLKEVPEASGPQNDGKQLCPPGNPSTLEKINKTSGPKRGKHAWTHRLRERKQLVVYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDE :::::::: NP_005 SDPEEDDE >>NP_005626 (OMIM: 300813,312820) protein SSX1 [Homo sap (188 aa) initn: 998 init1: 998 opt: 998 Z-score: 1007.5 bits: 193.1 E(85289): 2.2e-49 Smith-Waterman score: 998; 79.3% identity (88.8% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK :::::.::.::: :. :: .:.::::: :::::::.::: ::::::::::.:.:::: NP_005 MNGDDTFAKRPRDDAKASEKRSKAFDDIATYFSKKEWKKMKYSEKISYVYMKRNYKAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG ::::.:::::: : :::.::::::::.:. :::.::::: ::.::.::::::::::. NP_005 LGFKVTLPPFMCNKQATDFQGNDFDNDHNRRIQVEHPQMTFGRLHRIIPKIMPKKPAEDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSGPKRGKHAWTHRLRERKQLVIYEEI :::::: :::: :::::.: :::: . :::::: :::::::::::::::::::::::::: NP_005 NDSKGVSEASGPQNDGKQLHPPGKANISEKINKRSGPKRGKHAWTHRLRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDE :::::::: NP_005 SDPEEDDE 188 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:52:55 2016 done: Fri Nov 4 06:52:56 2016 Total Scan time: 5.500 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]