FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7366, 245 aa 1>>>pF1KB7366 245 - 245 aa - 245 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0318+/-0.000741; mu= 16.8462+/- 0.044 mean_var=76.0270+/-15.152, 0's: 0 Z-trim(109.9): 16 B-trim: 184 in 2/49 Lambda= 0.147092 statistics sampled from 11225 (11235) to 11225 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.345), width: 16 Scan time: 2.230 The best scores are: opt bits E(32554) CCDS73344.1 FOLR3 gene_id:2352|Hs108|chr11 ( 245) 1805 391.8 2.2e-109 CCDS8212.1 FOLR2 gene_id:2350|Hs108|chr11 ( 255) 1486 324.2 5.4e-89 CCDS8211.1 FOLR1 gene_id:2348|Hs108|chr11 ( 257) 1368 299.1 1.9e-81 CCDS81615.1 IZUMO1R gene_id:390243|Hs108|chr11 ( 250) 1007 222.5 2.1e-58 >>CCDS73344.1 FOLR3 gene_id:2352|Hs108|chr11 (245 aa) initn: 1805 init1: 1805 opt: 1805 Z-score: 2077.3 bits: 391.8 E(32554): 2.2e-109 Smith-Waterman score: 1805; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245) 10 20 30 40 50 60 pF1KB7 MDMAWQMMQLLLLALVTAAGSAQPRSARARTDLLNVCMNAKHHKTQPSPEDELYGQCSPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MDMAWQMMQLLLLALVTAAGSAQPRSARARTDLLNVCMNAKHHKTQPSPEDELYGQCSPW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPTCKRHFIQDSCLYECSPNLGPWIRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 KKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPTCKRHFIQDSCLYECSPNLGPWIRQV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NQSWRKERILNVPLCKEDCERWWEDCRTSYTCKSNWHKGWNWTSGINECPAGALCSTFES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 NQSWRKERILNVPLCKEDCERWWEDCRTSYTCKSNWHKGWNWTSGINECPAGALCSTFES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 YFPTPAALCEGLWSHSFKVSNYSRGSGRCIQMWFDSAQGNPNEEVAKFYAAAMNAGAPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 YFPTPAALCEGLWSHSFKVSNYSRGSGRCIQMWFDSAQGNPNEEVAKFYAAAMNAGAPSR 190 200 210 220 230 240 pF1KB7 GIIDS ::::: CCDS73 GIIDS >>CCDS8212.1 FOLR2 gene_id:2350|Hs108|chr11 (255 aa) initn: 1485 init1: 1455 opt: 1486 Z-score: 1711.3 bits: 324.2 E(32554): 5.4e-89 Smith-Waterman score: 1486; 82.6% identity (92.5% similar) in 241 aa overlap (3-241:1-237) 10 20 30 40 50 60 pF1KB7 MDMAWQMMQLLLLALVTAAGSAQPRSARARTDLLNVCMNAKHHKTQPSPEDELYGQCSPW :.:. : :::: :: .: ::. :::::::::.::::::.:.:::.:. ::::: CCDS82 MVWKWMPLLLL-LVCVATMC---SAQDRTDLLNVCMDAKHHKTKPGPEDKLHDQCSPW 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 KKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPTCKRHFIQDSCLYECSPNLGPWIRQV ::::::::::::::::::::::::::::::::::.::::::::.:::::::::::::.:: CCDS82 KKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIQQV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 NQSWRKERILNVPLCKEDCERWWEDCRTSYTCKSNWHKGWNWTSGINECPAGALCSTFES ::::::::.:.::::::::.::::::.::.:::::::.::.::::.:.::::::: :::: CCDS82 NQSWRKERFLDVPLCKEDCQRWWEDCHTSHTCKSNWHRGWDWTSGVNKCPAGALCRTFES 120 130 140 150 160 170 190 200 210 220 230 pF1KB7 YFPTPAALCEGLWSHSFKVSNYSRGSGRCIQMWFDSAQGNPNEEVAKFYAAAM--NAGAP ::::::::::::::::.:::::::::::::::::::::::::::::.:::::: ::: CCDS82 YFPTPAALCEGLWSHSYKVSNYSRGSGRCIQMWFDSAQGNPNEEVARFYAAAMHVNAGEM 180 190 200 210 220 230 240 pF1KB7 SRGIIDS .: CCDS82 LHGTGGLLLSLALMLQLWLLG 240 250 >>CCDS8211.1 FOLR1 gene_id:2348|Hs108|chr11 (257 aa) initn: 1409 init1: 1365 opt: 1368 Z-score: 1575.9 bits: 299.1 E(32554): 1.9e-81 Smith-Waterman score: 1368; 74.4% identity (89.5% similar) in 238 aa overlap (3-238:1-238) 10 20 30 40 50 pF1KB7 MDMAWQMMQLLLLALVTAA--GSAQPRSARARTDLLNVCMNAKHHKTQPSPEDELYGQCS :: .: ::: :: .: : :: : : :::.:::::::::::: .:.:::.:. :: CCDS82 MAQRMTTQLLLLLVWVAVVGEAQTRIAWARTELLNVCMNAKHHKEKPGPEDKLHEQCR 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 PWKKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPTCKRHFIQDSCLYECSPNLGPWIR ::.:::::...:::: :::.: :: :::.:::.: :.::::::::.:::::::::::::. CCDS82 PWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 QVNQSWRKERILNVPLCKEDCERWWEDCRTSYTCKSNWHKGWNWTSGINECPAGALCSTF ::.:::::::.:::::::::::.::::::::::::::::::::::::.:.: .:: :. : CCDS82 QVDQSWRKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 ESYFPTPAALCEGLWSHSFKVSNYSRGSGRCIQMWFDSAQGNPNEEVAKFYAAAMNAGAP . :::::..::. .:.::.:::::::::::::::::: ::::::::::.::::::....: CCDS82 HFYFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAAMSGAGP 180 190 200 210 220 230 240 pF1KB7 SRGIIDS CCDS82 WAAWPFLLSLALMLLWLLS 240 250 >>CCDS81615.1 IZUMO1R gene_id:390243|Hs108|chr11 (250 aa) initn: 1010 init1: 561 opt: 1007 Z-score: 1162.0 bits: 222.5 E(32554): 2.1e-58 Smith-Waterman score: 1007; 56.2% identity (72.7% similar) in 242 aa overlap (5-239:5-232) 10 20 30 40 50 60 pF1KB7 MDMAWQMMQLLLLALVTAAGSAQPRSARARTDLLNVCMNAKHHKTQPSPEDELYGQCSPW : .. : .. : ::. .:::.:::::::: :::::.:: .: :: CCDS81 MACWWPLLLELWTVMPTWAGD----------ELLNICMNAKHHKRVPSPEDKLYEECIPW 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 KKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPTCKRHFIQDSCLYECSPNLGPWIRQV : ::::: .:: : : :.: ::::. ::: . : :..:::: :.:::::::::::. : CCDS81 KDNACCTLTTSWEAHLDVSPLYNFSLFHCGLLMPGCRKHFIQAICFYECSPNLGPWIQPV 60 70 80 90 100 110 130 140 150 160 170 pF1KB7 NQ-SW------RKERILNVPLCKEDCERWWEDCRTSYTCKSNWHKGWNWTSGINECPAGA .. .: . ::..:::::.::::.:::::: ::::::::. ::.:..: :.:: :: CCDS81 GSLGWEVAPSGQGERVVNVPLCQEDCEEWWEDCRMSYTCKSNWRGGWDWSQGKNRCPKGA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LCSTFESYFPTPAALCEGLWSHSFKVSNYSRGSGRCIQMWFDSAQGNPNEEVAKFYAAAM : : :::::: ::: ::.:::.: :.::::.: ::. :::::: ::...:.. CCDS81 QCLPFSHYFPTPADLCEKTWSNSFKASPERRNSGRCLQKWFEPAQGNPNVAVARLFASS- 180 190 200 210 220 240 pF1KB7 NAGAPSRGIIDS ::: CCDS81 ---APSWELSYTIMVCSLFLPFLS 230 240 250 245 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:53:28 2016 done: Fri Nov 4 06:53:28 2016 Total Scan time: 2.230 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]