FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7367, 161 aa 1>>>pF1KB7367 161 - 161 aa - 161 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7227+/-0.000251; mu= 16.0428+/- 0.016 mean_var=66.3464+/-13.645, 0's: 0 Z-trim(121.5): 16 B-trim: 1122 in 1/50 Lambda= 0.157458 statistics sampled from 38267 (38283) to 38267 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.809), E-opt: 0.2 (0.449), width: 16 Scan time: 5.970 The best scores are: opt bits E(85289) NP_835145 (OMIM: 615823) structure-specific endonu ( 161) 1171 273.6 9.9e-74 NP_001015000 (OMIM: 615822) structure-specific end ( 161) 1171 273.6 9.9e-74 NP_001014999 (OMIM: 615822) structure-specific end ( 275) 609 146.1 4e-35 NP_076949 (OMIM: 615823) structure-specific endonu ( 275) 609 146.1 4e-35 >>NP_835145 (OMIM: 615823) structure-specific endonuclea (161 aa) initn: 1171 init1: 1171 opt: 1171 Z-score: 1444.7 bits: 273.6 E(85289): 9.9e-74 Smith-Waterman score: 1171; 100.0% identity (100.0% similar) in 161 aa overlap (1-161:1-161) 10 20 30 40 50 60 pF1KB7 MGPAGVAARPGRFFGVYLLYCLNPRYRGRVYVGFTVNTARRVQQHNGGRKKGGAWRTSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_835 MGPAGVAARPGRFFGVYLLYCLNPRYRGRVYVGFTVNTARRVQQHNGGRKKGGAWRTSGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GPWEMVLVVHGFPSSVAALRDEEGPLCCPHPGCLLRAHVICLAEEFLQEEPGQLLPLEGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_835 GPWEMVLVVHGFPSSVAALRDEEGPLCCPHPGCLLRAHVICLAEEFLQEEPGQLLPLEGQ 70 80 90 100 110 120 130 140 150 160 pF1KB7 CPCCEKSLLWGDLIWLCQMDTEKEVEDSELEEAHWTDLLET ::::::::::::::::::::::::::::::::::::::::: NP_835 CPCCEKSLLWGDLIWLCQMDTEKEVEDSELEEAHWTDLLET 130 140 150 160 >>NP_001015000 (OMIM: 615822) structure-specific endonuc (161 aa) initn: 1171 init1: 1171 opt: 1171 Z-score: 1444.7 bits: 273.6 E(85289): 9.9e-74 Smith-Waterman score: 1171; 100.0% identity (100.0% similar) in 161 aa overlap (1-161:1-161) 10 20 30 40 50 60 pF1KB7 MGPAGVAARPGRFFGVYLLYCLNPRYRGRVYVGFTVNTARRVQQHNGGRKKGGAWRTSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGPAGVAARPGRFFGVYLLYCLNPRYRGRVYVGFTVNTARRVQQHNGGRKKGGAWRTSGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GPWEMVLVVHGFPSSVAALRDEEGPLCCPHPGCLLRAHVICLAEEFLQEEPGQLLPLEGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPWEMVLVVHGFPSSVAALRDEEGPLCCPHPGCLLRAHVICLAEEFLQEEPGQLLPLEGQ 70 80 90 100 110 120 130 140 150 160 pF1KB7 CPCCEKSLLWGDLIWLCQMDTEKEVEDSELEEAHWTDLLET ::::::::::::::::::::::::::::::::::::::::: NP_001 CPCCEKSLLWGDLIWLCQMDTEKEVEDSELEEAHWTDLLET 130 140 150 160 >>NP_001014999 (OMIM: 615822) structure-specific endonuc (275 aa) initn: 609 init1: 609 opt: 609 Z-score: 751.7 bits: 146.1 E(85289): 4e-35 Smith-Waterman score: 609; 97.6% identity (100.0% similar) in 83 aa overlap (79-161:193-275) 50 60 70 80 90 100 pF1KB7 RKKGGAWRTSGRGPWEMVLVVHGFPSSVAALRDEEGPLCCPHPGCLLRAHVICLAEEFLQ ..:::::::::::::::::::::::::::: NP_001 PRRRAGPFDDAEPEPDQGDPGACCSLCAQTIQDEEGPLCCPHPGCLLRAHVICLAEEFLQ 170 180 190 200 210 220 110 120 130 140 150 160 pF1KB7 EEPGQLLPLEGQCPCCEKSLLWGDLIWLCQMDTEKEVEDSELEEAHWTDLLET ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEPGQLLPLEGQCPCCEKSLLWGDLIWLCQMDTEKEVEDSELEEAHWTDLLET 230 240 250 260 270 >-- initn: 583 init1: 565 opt: 569 Z-score: 702.5 bits: 137.0 E(85289): 2.2e-32 Smith-Waterman score: 569; 87.9% identity (88.9% similar) in 99 aa overlap (1-99:1-97) 10 20 30 40 50 60 pF1KB7 MGPAGVAARPGRFFGVYLLYCLNPRYRGRVYVGFTVNTARRVQQHNGGRKKGGAWRTSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGPAGVAARPGRFFGVYLLYCLNPRYRGRVYVGFTVNTARRVQQHNGGRKKGGAWRTSGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GPWEMVLVVHGFPSSVAALRDEEGPLCCPHPGCLLRAHVICLAEEFLQEEPGQLLPLEGQ :::::::::::::::::::: : :: . : ::: NP_001 GPWEMVLVVHGFPSSVAALR-FEWAWQHPHASRRL-AHVGPRLRGETAFAFHLRVLAHML 70 80 90 100 110 130 140 150 160 pF1KB7 CPCCEKSLLWGDLIWLCQMDTEKEVEDSELEEAHWTDLLET NP_001 RAPPWARLPLTLRWVRPDLRQDLCLPPPPHVPLAFGPPPPQAPAPRRRAGPFDDAEPEPD 120 130 140 150 160 170 >>NP_076949 (OMIM: 615823) structure-specific endonuclea (275 aa) initn: 609 init1: 609 opt: 609 Z-score: 751.7 bits: 146.1 E(85289): 4e-35 Smith-Waterman score: 609; 97.6% identity (100.0% similar) in 83 aa overlap (79-161:193-275) 50 60 70 80 90 100 pF1KB7 RKKGGAWRTSGRGPWEMVLVVHGFPSSVAALRDEEGPLCCPHPGCLLRAHVICLAEEFLQ ..:::::::::::::::::::::::::::: NP_076 PRRRAGPFDDAEPEPDQGDPGACCSLCAQTIQDEEGPLCCPHPGCLLRAHVICLAEEFLQ 170 180 190 200 210 220 110 120 130 140 150 160 pF1KB7 EEPGQLLPLEGQCPCCEKSLLWGDLIWLCQMDTEKEVEDSELEEAHWTDLLET ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 EEPGQLLPLEGQCPCCEKSLLWGDLIWLCQMDTEKEVEDSELEEAHWTDLLET 230 240 250 260 270 >-- initn: 583 init1: 565 opt: 569 Z-score: 702.5 bits: 137.0 E(85289): 2.2e-32 Smith-Waterman score: 569; 87.9% identity (88.9% similar) in 99 aa overlap (1-99:1-97) 10 20 30 40 50 60 pF1KB7 MGPAGVAARPGRFFGVYLLYCLNPRYRGRVYVGFTVNTARRVQQHNGGRKKGGAWRTSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 MGPAGVAARPGRFFGVYLLYCLNPRYRGRVYVGFTVNTARRVQQHNGGRKKGGAWRTSGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GPWEMVLVVHGFPSSVAALRDEEGPLCCPHPGCLLRAHVICLAEEFLQEEPGQLLPLEGQ :::::::::::::::::::: : :: . : ::: NP_076 GPWEMVLVVHGFPSSVAALR-FEWAWQHPHASRRL-AHVGPRLRGETAFAFHLRVLAHML 70 80 90 100 110 130 140 150 160 pF1KB7 CPCCEKSLLWGDLIWLCQMDTEKEVEDSELEEAHWTDLLET NP_076 RAPPWARLPLTLRWVRPDLRQDLCLPPPPHVPLAFGPPPPQAPAPRRRAGPFDDAEPEPD 120 130 140 150 160 170 161 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:54:02 2016 done: Fri Nov 4 06:54:02 2016 Total Scan time: 5.970 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]