FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7376, 330 aa 1>>>pF1KB7376 330 - 330 aa - 330 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8111+/-0.00034; mu= 14.4638+/- 0.021 mean_var=84.7822+/-16.606, 0's: 0 Z-trim(116.1): 10 B-trim: 317 in 1/51 Lambda= 0.139291 statistics sampled from 27022 (27032) to 27022 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.317), width: 16 Scan time: 7.610 The best scores are: opt bits E(85289) NP_872295 (OMIM: 609987) stimulated by retinoic ac ( 330) 2168 445.2 8.8e-125 XP_011514441 (OMIM: 609987) PREDICTED: stimulated ( 379) 1200 250.7 3.6e-66 XP_011514439 (OMIM: 609987) PREDICTED: stimulated ( 379) 1200 250.7 3.6e-66 XP_011514440 (OMIM: 609987) PREDICTED: stimulated ( 379) 1200 250.7 3.6e-66 XP_016867639 (OMIM: 609987) PREDICTED: stimulated ( 239) 809 172.0 1.1e-42 >>NP_872295 (OMIM: 609987) stimulated by retinoic acid g (330 aa) initn: 2168 init1: 2168 opt: 2168 Z-score: 2361.2 bits: 445.2 E(85289): 8.8e-125 Smith-Waterman score: 2168; 100.0% identity (100.0% similar) in 330 aa overlap (1-330:1-330) 10 20 30 40 50 60 pF1KB7 MGKIDVDKILFFNQEIRLWQLIMATPEENSNPHDRATPQLPAQLQELEHRVARRRLSQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_872 MGKIDVDKILFFNQEIRLWQLIMATPEENSNPHDRATPQLPAQLQELEHRVARRRLSQAR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 HRATLAALFNNLRKTVYSQSDLIASKWQVLNKAKSHIPELEQTLDNLLKLKASFNLEDGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_872 HRATLAALFNNLRKTVYSQSDLIASKWQVLNKAKSHIPELEQTLDNLLKLKASFNLEDGH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ASSLEEVKKEYASMYSGNDSFPQNGSSPWYLNFYKQTMDLLTGSGIITPQEAALPIVSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_872 ASSLEEVKKEYASMYSGNDSFPQNGSSPWYLNFYKQTMDLLTGSGIITPQEAALPIVSAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ISHLWQNLSEERKASLRQAWAQKHRGPATLAEACREPACAEGSVKDSGVDSQGASCSLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_872 ISHLWQNLSEERKASLRQAWAQKHRGPATLAEACREPACAEGSVKDSGVDSQGASCSLVS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TPEEILFEDAFDVASFLDKSEVPSTSSSSSVLASCNPENPEEKFQLYMQIINFFKGLSCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_872 TPEEILFEDAFDVASFLDKSEVPSTSSSSSVLASCNPENPEEKFQLYMQIINFFKGLSCA 250 260 270 280 290 300 310 320 330 pF1KB7 NTQVKQEASFPVDEEMIMLQCTETFDDEDL :::::::::::::::::::::::::::::: NP_872 NTQVKQEASFPVDEEMIMLQCTETFDDEDL 310 320 330 >>XP_011514441 (OMIM: 609987) PREDICTED: stimulated by r (379 aa) initn: 1200 init1: 1200 opt: 1200 Z-score: 1309.0 bits: 250.7 E(85289): 3.6e-66 Smith-Waterman score: 1738; 80.4% identity (80.4% similar) in 362 aa overlap (40-330:18-379) 10 20 30 40 50 60 pF1KB7 LFFNQEIRLWQLIMATPEENSNPHDRATPQLPAQLQELEHRVARRRLSQARHRATLAALF :::::::::::::::::::::::::::::: XP_011 MATPEENSNPHDRATPQLPAQLQELEHRVARRRLSQARHRATLAALF 10 20 30 40 70 80 90 100 110 120 pF1KB7 NNLRKTVYSQSDLIASKWQVLNKAKSHIPELEQTLDNLLKLKASFNLEDGHASSLEEVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNLRKTVYSQSDLIASKWQVLNKAKSHIPELEQTLDNLLKLKASFNLEDGHASSLEEVKK 50 60 70 80 90 100 130 140 pF1KB7 EYASMYSGNDS-----FPQNGSSPW----------------------------------- ::::::::::: ::::::::: XP_011 EYASMYSGNDSLLSNSFPQNGSSPWCPTEAVRKDAEEEEDEEEEDQEEEEEEEEEEEEEE 110 120 130 140 150 160 150 160 170 pF1KB7 -------------------------------YLNFYKQTMDLLTGSGIITPQEAALPIVS ::::::::::::::::::::::::::::: XP_011 EEEEEEEEEEEKKVILYSPGTLSPDLMEFERYLNFYKQTMDLLTGSGIITPQEAALPIVS 170 180 190 200 210 220 180 190 200 210 220 230 pF1KB7 AAISHLWQNLSEERKASLRQAWAQKHRGPATLAEACREPACAEGSVKDSGVDSQGASCSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAISHLWQNLSEERKASLRQAWAQKHRGPATLAEACREPACAEGSVKDSGVDSQGASCSL 230 240 250 260 270 280 240 250 260 270 280 290 pF1KB7 VSTPEEILFEDAFDVASFLDKSEVPSTSSSSSVLASCNPENPEEKFQLYMQIINFFKGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSTPEEILFEDAFDVASFLDKSEVPSTSSSSSVLASCNPENPEEKFQLYMQIINFFKGLS 290 300 310 320 330 340 300 310 320 330 pF1KB7 CANTQVKQEASFPVDEEMIMLQCTETFDDEDL :::::::::::::::::::::::::::::::: XP_011 CANTQVKQEASFPVDEEMIMLQCTETFDDEDL 350 360 370 >>XP_011514439 (OMIM: 609987) PREDICTED: stimulated by r (379 aa) initn: 1200 init1: 1200 opt: 1200 Z-score: 1309.0 bits: 250.7 E(85289): 3.6e-66 Smith-Waterman score: 1738; 80.4% identity (80.4% similar) in 362 aa overlap (40-330:18-379) 10 20 30 40 50 60 pF1KB7 LFFNQEIRLWQLIMATPEENSNPHDRATPQLPAQLQELEHRVARRRLSQARHRATLAALF :::::::::::::::::::::::::::::: XP_011 MATPEENSNPHDRATPQLPAQLQELEHRVARRRLSQARHRATLAALF 10 20 30 40 70 80 90 100 110 120 pF1KB7 NNLRKTVYSQSDLIASKWQVLNKAKSHIPELEQTLDNLLKLKASFNLEDGHASSLEEVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNLRKTVYSQSDLIASKWQVLNKAKSHIPELEQTLDNLLKLKASFNLEDGHASSLEEVKK 50 60 70 80 90 100 130 140 pF1KB7 EYASMYSGNDS-----FPQNGSSPW----------------------------------- ::::::::::: ::::::::: XP_011 EYASMYSGNDSLLSNSFPQNGSSPWCPTEAVRKDAEEEEDEEEEDQEEEEEEEEEEEEEE 110 120 130 140 150 160 150 160 170 pF1KB7 -------------------------------YLNFYKQTMDLLTGSGIITPQEAALPIVS ::::::::::::::::::::::::::::: XP_011 EEEEEEEEEEEKKVILYSPGTLSPDLMEFERYLNFYKQTMDLLTGSGIITPQEAALPIVS 170 180 190 200 210 220 180 190 200 210 220 230 pF1KB7 AAISHLWQNLSEERKASLRQAWAQKHRGPATLAEACREPACAEGSVKDSGVDSQGASCSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAISHLWQNLSEERKASLRQAWAQKHRGPATLAEACREPACAEGSVKDSGVDSQGASCSL 230 240 250 260 270 280 240 250 260 270 280 290 pF1KB7 VSTPEEILFEDAFDVASFLDKSEVPSTSSSSSVLASCNPENPEEKFQLYMQIINFFKGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSTPEEILFEDAFDVASFLDKSEVPSTSSSSSVLASCNPENPEEKFQLYMQIINFFKGLS 290 300 310 320 330 340 300 310 320 330 pF1KB7 CANTQVKQEASFPVDEEMIMLQCTETFDDEDL :::::::::::::::::::::::::::::::: XP_011 CANTQVKQEASFPVDEEMIMLQCTETFDDEDL 350 360 370 >>XP_011514440 (OMIM: 609987) PREDICTED: stimulated by r (379 aa) initn: 1200 init1: 1200 opt: 1200 Z-score: 1309.0 bits: 250.7 E(85289): 3.6e-66 Smith-Waterman score: 1738; 80.4% identity (80.4% similar) in 362 aa overlap (40-330:18-379) 10 20 30 40 50 60 pF1KB7 LFFNQEIRLWQLIMATPEENSNPHDRATPQLPAQLQELEHRVARRRLSQARHRATLAALF :::::::::::::::::::::::::::::: XP_011 MATPEENSNPHDRATPQLPAQLQELEHRVARRRLSQARHRATLAALF 10 20 30 40 70 80 90 100 110 120 pF1KB7 NNLRKTVYSQSDLIASKWQVLNKAKSHIPELEQTLDNLLKLKASFNLEDGHASSLEEVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNLRKTVYSQSDLIASKWQVLNKAKSHIPELEQTLDNLLKLKASFNLEDGHASSLEEVKK 50 60 70 80 90 100 130 140 pF1KB7 EYASMYSGNDS-----FPQNGSSPW----------------------------------- ::::::::::: ::::::::: XP_011 EYASMYSGNDSLLSNSFPQNGSSPWCPTEAVRKDAEEEEDEEEEDQEEEEEEEEEEEEEE 110 120 130 140 150 160 150 160 170 pF1KB7 -------------------------------YLNFYKQTMDLLTGSGIITPQEAALPIVS ::::::::::::::::::::::::::::: XP_011 EEEEEEEEEEEKKVILYSPGTLSPDLMEFERYLNFYKQTMDLLTGSGIITPQEAALPIVS 170 180 190 200 210 220 180 190 200 210 220 230 pF1KB7 AAISHLWQNLSEERKASLRQAWAQKHRGPATLAEACREPACAEGSVKDSGVDSQGASCSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAISHLWQNLSEERKASLRQAWAQKHRGPATLAEACREPACAEGSVKDSGVDSQGASCSL 230 240 250 260 270 280 240 250 260 270 280 290 pF1KB7 VSTPEEILFEDAFDVASFLDKSEVPSTSSSSSVLASCNPENPEEKFQLYMQIINFFKGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSTPEEILFEDAFDVASFLDKSEVPSTSSSSSVLASCNPENPEEKFQLYMQIINFFKGLS 290 300 310 320 330 340 300 310 320 330 pF1KB7 CANTQVKQEASFPVDEEMIMLQCTETFDDEDL :::::::::::::::::::::::::::::::: XP_011 CANTQVKQEASFPVDEEMIMLQCTETFDDEDL 350 360 370 >>XP_016867639 (OMIM: 609987) PREDICTED: stimulated by r (239 aa) initn: 758 init1: 758 opt: 809 Z-score: 887.3 bits: 172.0 E(85289): 1.1e-42 Smith-Waterman score: 809; 96.2% identity (96.2% similar) in 132 aa overlap (23-149:1-132) 10 20 30 40 50 60 pF1KB7 MGKIDVDKILFFNQEIRLWQLIMATPEENSNPHDRATPQLPAQLQELEHRVARRRLSQAR :::::::::::::::::::::::::::::::::::::: XP_016 MATPEENSNPHDRATPQLPAQLQELEHRVARRRLSQAR 10 20 30 70 80 90 100 110 120 pF1KB7 HRATLAALFNNLRKTVYSQSDLIASKWQVLNKAKSHIPELEQTLDNLLKLKASFNLEDGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRATLAALFNNLRKTVYSQSDLIASKWQVLNKAKSHIPELEQTLDNLLKLKASFNLEDGH 40 50 60 70 80 90 130 140 150 160 170 pF1KB7 ASSLEEVKKEYASMYSGNDS-----FPQNGSSPWYLNFYKQTMDLLTGSGIITPQEAALP :::::::::::::::::::: ::::::::: XP_016 ASSLEEVKKEYASMYSGNDSLLSNSFPQNGSSPWCPTEAVRKDAEEEEDEEEEDQEEEEE 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 IVSAAISHLWQNLSEERKASLRQAWAQKHRGPATLAEACREPACAEGSVKDSGVDSQGAS XP_016 EEEEEEEEEEEEEEEEEEEEKKVILYSPGTLSPDLMEFERCEQLGGVALCTHGAPSHGEG 160 170 180 190 200 210 330 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 07:00:31 2016 done: Fri Nov 4 07:00:32 2016 Total Scan time: 7.610 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]