FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7378, 278 aa
  1>>>pF1KB7378 278 - 278 aa - 278 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.9936+/-0.000763; mu= 10.0822+/- 0.046
 mean_var=184.1889+/-35.480, 0's: 0 Z-trim(116.4): 48  B-trim: 56 in 2/52
 Lambda= 0.094502
 statistics sampled from 16984 (17036) to 16984 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.826), E-opt: 0.2 (0.523), width:  16
 Scan time:  2.730

The best scores are:                                      opt bits E(32554)
CCDS35017.1 IGFBPL1 gene_id:347252|Hs108|chr9      ( 278) 1990 282.6 2.2e-76
CCDS58900.1 IGFBP7 gene_id:3490|Hs108|chr4         ( 279)  654 100.4 1.5e-21
CCDS3512.1 IGFBP7 gene_id:3490|Hs108|chr4          ( 282)  654 100.4 1.5e-21
CCDS7509.1 KAZALD1 gene_id:81621|Hs108|chr10       ( 304)  529 83.4 2.1e-16


>>CCDS35017.1 IGFBPL1 gene_id:347252|Hs108|chr9           (278 aa)
 initn: 1990 init1: 1990 opt: 1990  Z-score: 1484.9  bits: 282.6 E(32554): 2.2e-76
Smith-Waterman score: 1990; 100.0% identity (100.0% similar) in 278 aa overlap (1-278:1-278)

               10        20        30        40        50        60
pF1KB7 MPRLSLLLPLLLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 MPRLSLLLPLLLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 DECGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAPEGTGLCVCAQRGTVCGSDGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 DECGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAPEGTGLCVCAQRGTVCGSDGR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 SYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 SYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 VPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 VPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGV
              190       200       210       220       230       240

              250       260       270        
pF1KB7 YQCHAANMVGEAESHSTVTVLDLSKYRSFHFPAPDDRM
       ::::::::::::::::::::::::::::::::::::::
CCDS35 YQCHAANMVGEAESHSTVTVLDLSKYRSFHFPAPDDRM
              250       260       270        

>>CCDS58900.1 IGFBP7 gene_id:3490|Hs108|chr4              (279 aa)
 initn: 746 init1: 589 opt: 654  Z-score: 500.5  bits: 100.4 E(32554): 1.5e-21
Smith-Waterman score: 776; 44.7% identity (63.7% similar) in 273 aa overlap (2-262:4-267)

                  10        20        30        40        50       
pF1KB7   MPRL-SLLLPLLLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGI
          : : .:::    :::  :: ::: :       .    ::::.: .::   :      
CCDS58 MERPSLRALLLGAAGLLL--LLLPLSSS-------SSSDTCGPCEPASCPPLPPLGCLLG
               10          20               30        40        50 

        60        70        80          90             100         
pF1KB7 SALDECGCCARCLGAEGASCGGRAGGR--CGPGLVCASQ------AAGAAPEG---TGLC
        . : ::::  :  .::  ::: ..::  :.::. :...       ::::  :   .:.:
CCDS58 ETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVC
              60        70        80        90       100       110 

        110       120       130       140       150       160      
pF1KB7 VCAQRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHN
       :: .:  :::::: .::: : ::  ....       . ..  : :: .: .:.::... :
CCDS58 VCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWN
             120       130       140       150       160       170 

        170       180       190       200       210       220      
pF1KB7 VTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATA
       :::::: ::::: ..::::. : :: ..  :.:  : ::::. :.:.:.::::  ::.:.
CCDS58 VTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTG
             180       190       200       210       220       230 

        230       240       250       260       270        
pF1KB7 WILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRSFHFPAPDDRM
       :.:..:: ::: : :.:::.:  :.: . . .::.:                
CCDS58 WVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGTQ    
             240       250       260       270             

>>CCDS3512.1 IGFBP7 gene_id:3490|Hs108|chr4               (282 aa)
 initn: 746 init1: 589 opt: 654  Z-score: 500.4  bits: 100.4 E(32554): 1.5e-21
Smith-Waterman score: 776; 44.7% identity (63.7% similar) in 273 aa overlap (2-262:4-267)

                  10        20        30        40        50       
pF1KB7   MPRL-SLLLPLLLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGI
          : : .:::    :::  :: ::: :       .    ::::.: .::   :      
CCDS35 MERPSLRALLLGAAGLLL--LLLPLSSS-------SSSDTCGPCEPASCPPLPPLGCLLG
               10          20               30        40        50 

        60        70        80          90             100         
pF1KB7 SALDECGCCARCLGAEGASCGGRAGGR--CGPGLVCASQ------AAGAAPEG---TGLC
        . : ::::  :  .::  ::: ..::  :.::. :...       ::::  :   .:.:
CCDS35 ETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVC
              60        70        80        90       100       110 

        110       120       130       140       150       160      
pF1KB7 VCAQRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHN
       :: .:  :::::: .::: : ::  ....       . ..  : :: .: .:.::... :
CCDS35 VCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWN
             120       130       140       150       160       170 

        170       180       190       200       210       220      
pF1KB7 VTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATA
       :::::: ::::: ..::::. : :: ..  :.:  : ::::. :.:.:.::::  ::.:.
CCDS35 VTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTG
             180       190       200       210       220       230 

        230       240       250       260       270        
pF1KB7 WILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRSFHFPAPDDRM
       :.:..:: ::: : :.:::.:  :.: . . .::.:                
CCDS35 WVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGEGAEL 
             240       250       260       270       280   

>>CCDS7509.1 KAZALD1 gene_id:81621|Hs108|chr10            (304 aa)
 initn: 624 init1: 193 opt: 529  Z-score: 407.9  bits: 83.4 E(32554): 2.1e-16
Smith-Waterman score: 627; 38.8% identity (59.1% similar) in 291 aa overlap (2-272:7-282)

                    10        20        30                     40  
pF1KB7      MPRLSLLLPLLLLLLLPLLPPLSPSLGIRDVGG----RR---------PKCGPCR
             :  .: ::.:::::. : ::  :. : :   :    ::           :.:::
CCDS75 MLPPPRPAAALALPVLLLLLVVLTPP--PT-GARPSPGPDYLRRGWMRLLAEGEGCAPCR
               10        20           30        40        50       

             50        60        70            80        90        
pF1KB7 PEGCPAPAPCPAPGISALDECGCCARCLGAEGASC----GGRAGGRCGPGLVCASQAAGA
       :: : ::  : :  .   : :::: .: . ::  :    ...  :.::  : :  ...: 
CCDS75 PEECAAPRGCLAGRVR--DACGCCWECANLEGQLCDLDPSAHFYGHCGEQLECRLDTGGD
        60        70          80        90       100       110     

      100          110       120       130       140       150     
pF1KB7 APEGT---GLCVCAQRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAP
         .:     ::.: ... .:::::..: ..: :.  ::  : :.   :  :. :::: .:
CCDS75 LSRGEVPEPLCACRSQSPLCGSDGHTYSQICRLQEAARARPDAN---LTVAHPGPCESGP
         120       130       140       150          160       170  

         160       170       180       190       200       210     
pF1KB7 VVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQV
        .:  : .. :::: .: ..::: : :   : :::     .: .   .::::  .:.:: 
CCDS75 QIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRK-----DGLDI--QLPGDDPHISVQF
            180       190       200            210         220     

         220       230       240       250       260       270     
pF1KB7 RGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRSFHFPAPD
       ::::.  :.:.:. :. .:  :::.:.: . : .:..:. ...:::  ..  :  .:   
CCDS75 RGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLR
         230       240       250       260       270       280     

                          
pF1KB7 DRM                
                          
CCDS75 SLNLVPEEEAESEENDDYY
         290       300    




278 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 07:01:44 2016 done: Fri Nov  4 07:01:44 2016
 Total Scan time:  2.730 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]