Result of FASTA (ccds) for pF1KB7381
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7381, 462 aa
  1>>>pF1KB7381 462 - 462 aa - 462 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.2536+/-0.000871; mu= 1.2865+/- 0.052
 mean_var=244.3157+/-49.439, 0's: 0 Z-trim(115.4): 16  B-trim: 167 in 1/50
 Lambda= 0.082054
 statistics sampled from 15999 (16010) to 15999 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.492), width:  16
 Scan time:  4.000

The best scores are:                                      opt bits E(32554)
CCDS45510.1 HSF4 gene_id:3299|Hs108|chr16          ( 462) 3168 387.7 1.3e-107
CCDS42175.1 HSF4 gene_id:3299|Hs108|chr16          ( 492) 1679 211.5 1.6e-54
CCDS6419.1 HSF1 gene_id:3297|Hs108|chr8            ( 529)  890 118.1 2.2e-26
CCDS47470.1 HSF2 gene_id:3298|Hs108|chr6           ( 518)  649 89.6 8.6e-18
CCDS5124.1 HSF2 gene_id:3298|Hs108|chr6            ( 536)  649 89.6 8.8e-18


>>CCDS45510.1 HSF4 gene_id:3299|Hs108|chr16               (462 aa)
 initn: 3168 init1: 3168 opt: 3168  Z-score: 2045.2  bits: 387.7 E(32554): 1.3e-107
Smith-Waterman score: 3168; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 IQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPGFLPPVMAGAPPPLPVAVVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 IQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPGFLPPVMAGAPPPLPVAVVQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 AILEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AILEGKGSFSPEGPRNAQQPEPGDPREIPDRGPLGLESGDRSPESLLPPMLLQPPQESVE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 PAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKDPTLGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 PAGPLDVLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKDPTLGAP
              370       380       390       400       410       420

              430       440       450       460  
pF1KB7 LLLDVQAALGGPALGLPGALTIYSTPESRTASYLGPEASPSP
       ::::::::::::::::::::::::::::::::::::::::::
CCDS45 LLLDVQAALGGPALGLPGALTIYSTPESRTASYLGPEASPSP
              430       440       450       460  

>>CCDS42175.1 HSF4 gene_id:3299|Hs108|chr16               (492 aa)
 initn: 2850 init1: 1679 opt: 1679  Z-score: 1092.2  bits: 211.5 E(32554): 1.6e-54
Smith-Waterman score: 2803; 87.6% identity (90.2% similar) in 492 aa overlap (1-462:1-492)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 VPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHGQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPYF
              190       200       210       220       230       240

                 250            260              270           280 
pF1KB7 IQSP---STYSLSQRQ-----IWALALTGPG------APSSL-TSQKTLHPLR----GPG
       ::::   .. .:: ..     :  .   .:.      .:::    .: :  :.    .::
CCDS42 IQSPLPETNLGLSPHRARGPIISDIPEDSPSPEGTRLSPSSDGRREKGLALLKEEPASPG
              250       260       270       280       290       300

                        290       300       310       320       330
pF1KB7 -------FLPP----VMAGAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPD
               : :      . :::::::::::::::::::::::::::::::::::::::::
CCDS42 GDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNAQQPEPGDPREIPD
              310       320       330       340       350       360

              340       350       360       370       380       390
pF1KB7 RGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 RGPLGLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGREWTLMDLDMELSLMQ
              370       380       390       400       410       420

              400       410       420       430       440       450
pF1KB7 PLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALGLPGALTIYSTPESRT
              430       440       450       460       470       480

              460  
pF1KB7 ASYLGPEASPSP
       ::::::::::::
CCDS42 ASYLGPEASPSP
              490  

>>CCDS6419.1 HSF1 gene_id:3297|Hs108|chr8                 (529 aa)
 initn: 728 init1: 587 opt: 890  Z-score: 587.0  bits: 118.1 E(32554): 2.2e-26
Smith-Waterman score: 902; 39.1% identity (58.6% similar) in 471 aa overlap (9-423:7-475)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
               :   ::: ::::: :::.::.:: :: :: :::::.:: : ::..:::::::
CCDS64   MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLP
                 10        20        30        40        50        

               70        80        90       100       110       120
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
       .::::.:::::::::::::::::: ::::::..:::: .::::: :.::.::::: ..::
CCDS64 KYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRK
       60        70        80        90       100       110        

                 130       140       150       160       170       
pF1KB7 VPA---LRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQS
       : .   :...: . : ... .:: .:: ..: ::  ...:  ....:: :::::..:::.
CCDS64 VTSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQK
      120       130       140       150       160       170        

       180       190       200       210        220       230      
pF1KB7 HGQQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLML-DEGSSCPTPAKFNTCPLPGALLQ
       :.::..:..:::: :.. .:..    : :::. ::: : ::.   :       :  .  .
CCDS64 HAQQQKVVNKLIQFLISLVQSN-RILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGS
      180       190       200        210       220       230       

        240       250       260       270       280                
pF1KB7 DPYFIQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPG---------FLPPVM
        ::   ::.  : :     :.: .::   :..:      :. .::           : : 
CCDS64 GPYSAPSPAYSSSSLYAPDAVASSGP-IISDITELAPASPMASPGGSIDERPLSSSPLVR
       240       250       260        270       280       290      

       290         300            310           320       330      
pF1KB7 AGAPPPLPVAV--VQAILEGKGS-----FSPEGPRNA----QQPEPGDPREIPD-RGPLG
       .   :: :     :.    :. :     .:: .  ..    ..: :..   . : ::   
CCDS64 VKEEPPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARGHTD
        300       310       320       330       340       350      

         340                                    350       360      
pF1KB7 LESGDRSPESLLPP-----------------------------MLLQPPQESVEPAGPLD
        :.   ::     :                              .:.    ::. .. ::
CCDS64 TEGRPPSPPPTSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDTSALLD
        360       370       380       390       400       410      

        370       380       390       400       410         420    
pF1KB7 VLGPSLQGREWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKDPT--LGAPLLLD
       ...::.   . .: :::  :. .: :.  .  :.      .::. ::. .   . ::.: 
CCDS64 LFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTAQPLFLL
        420       430       440       450       460       470      

          430       440       450       460                 
pF1KB7 VQAALGGPALGLPGALTIYSTPESRTASYLGPEASPSP               
                                                            
CCDS64 DPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS
        480       490       500       510       520         

>>CCDS47470.1 HSF2 gene_id:3298|Hs108|chr6                (518 aa)
 initn: 630 init1: 630 opt: 649  Z-score: 432.9  bits: 89.6 E(32554): 8.6e-18
Smith-Waterman score: 649; 50.7% identity (78.1% similar) in 201 aa overlap (15-214:5-203)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
                     : :::::.:::.:: .  :...: :: .: :::: :..:::::.::
CCDS47           MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILP
                         10        20        30        40        50

               70        80        90        100       110         
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDH-VEFQHPSFVRGREQLLERVRR
       .::::.:::::::::::::::::: :..: ... :::  :::::: : .:...::: ..:
CCDS47 KYFKHNNMASFVRQLNMYGFRKVVHIDSG-IVKQERDGPVEFQHPYFKQGQDDLLENIKR
               60        70         80        90       100         

     120       130       140       150       160       170         
pF1KB7 KVPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHG
       :: . . .... : ::: .... .: ..  ::. :.:: ::...:: ::.::  :: .:.
CCDS47 KVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHA
     110       120       130       140       150       160         

     180       190       200       210       220       230         
pF1KB7 QQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPY
       ::..:: :..: .   .: .   .. :::  :.:.                         
CCDS47 QQQQVIRKIVQFIVTLVQNNQL-VSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKV
     170       180       190        200       210       220        

     240       250       260       270       280       290         
pF1KB7 FIQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPGFLPPVMAGAPPPLPVAVV
                                                                   
CCDS47 PHSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVE
      230       240       250       260       270       280        

>>CCDS5124.1 HSF2 gene_id:3298|Hs108|chr6                 (536 aa)
 initn: 625 init1: 625 opt: 649  Z-score: 432.7  bits: 89.6 E(32554): 8.8e-18
Smith-Waterman score: 649; 50.7% identity (78.1% similar) in 201 aa overlap (15-214:5-203)

               10        20        30        40        50        60
pF1KB7 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
                     : :::::.:::.:: .  :...: :: .: :::: :..:::::.::
CCDS51           MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILP
                         10        20        30        40        50

               70        80        90        100       110         
pF1KB7 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDH-VEFQHPSFVRGREQLLERVRR
       .::::.:::::::::::::::::: :..: ... :::  :::::: : .:...::: ..:
CCDS51 KYFKHNNMASFVRQLNMYGFRKVVHIDSG-IVKQERDGPVEFQHPYFKQGQDDLLENIKR
               60        70         80        90       100         

     120       130       140       150       160       170         
pF1KB7 KVPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHG
       :: . . .... : ::: .... .: ..  ::. :.:: ::...:: ::.::  :: .:.
CCDS51 KVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHA
     110       120       130       140       150       160         

     180       190       200       210       220       230         
pF1KB7 QQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPY
       ::..:: :..: .   .: .   .. :::  :.:.                         
CCDS51 QQQQVIRKIVQFIVTLVQNNQL-VSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKV
     170       180       190        200       210       220        

     240       250       260       270       280       290         
pF1KB7 FIQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPGFLPPVMAGAPPPLPVAVV
                                                                   
CCDS51 PHSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVE
      230       240       250       260       270       280        




462 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 07:03:59 2016 done: Fri Nov  4 07:04:00 2016
 Total Scan time:  4.000 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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