FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7383, 350 aa 1>>>pF1KB7383 350 - 350 aa - 350 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7269+/-0.000332; mu= 1.4818+/- 0.021 mean_var=201.2564+/-40.606, 0's: 0 Z-trim(121.9): 18 B-trim: 38 in 1/56 Lambda= 0.090406 statistics sampled from 39266 (39290) to 39266 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.461), width: 16 Scan time: 9.120 The best scores are: opt bits E(85289) NP_008916 (OMIM: 606406) nuclear pore complex-inte ( 350) 2426 328.4 1.4e-89 XP_011521051 (OMIM: 606406) PREDICTED: nuclear por ( 350) 2426 328.4 1.4e-89 XP_011521050 (OMIM: 606406) PREDICTED: nuclear por ( 377) 2259 306.7 5.5e-83 XP_016879380 (OMIM: 606406) PREDICTED: nuclear por ( 232) 1460 202.3 8.8e-52 XP_011521053 (OMIM: 606406) PREDICTED: nuclear por ( 259) 1293 180.5 3.5e-45 XP_011521052 (OMIM: 606406) PREDICTED: nuclear por ( 341) 1206 169.3 1.1e-41 >>NP_008916 (OMIM: 606406) nuclear pore complex-interact (350 aa) initn: 2426 init1: 2426 opt: 2426 Z-score: 1729.0 bits: 328.4 E(85289): 1.4e-89 Smith-Waterman score: 2426; 99.4% identity (100.0% similar) in 350 aa overlap (1-350:1-350) 10 20 30 40 50 60 pF1KB7 MFCCLGYEWLSGGCKTWHSAWVINTLADHRHRGTDFGGSPWLLIITVFLRSYKFAISLCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MFCCLGYEWLSGGCKTWHSAWVINTLADHRHRGTDFGGSPWLLIITVFLRSYKFAISLCT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEGIKIVLEDIFTLWRQVETKVRAK .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 SYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEGIKIVLEDIFTLWRQVETKVRAK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHGEKERQVSEAEENGKLDMKEIHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 IRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHGEKERQVSEAEENGKLDMKEIHT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 YMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMAAVEHRHSSGLPYWPYLTAETLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 YMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMAAVEHRHSSGLPYWPYLTAETLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 NRMGHQPPPPTQQHSIIDNSLSLKTPSECLLTPLPPSALPSADDNLKTPAECLLYPLPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 NRMGHQPPPPTQQHSIIDNSLSLKTPSECLLTPLPPSALPSADDNLKTPAECLLYPLPPS 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 ADDNLKTPPECLLTPLPPSAPPSADDNLKTPPECVCSLPFHPQRMIISRN :::::::::::::::::::::::.:::::::::::::::::::::::::: NP_008 ADDNLKTPPECLLTPLPPSAPPSVDDNLKTPPECVCSLPFHPQRMIISRN 310 320 330 340 350 >>XP_011521051 (OMIM: 606406) PREDICTED: nuclear pore co (350 aa) initn: 2426 init1: 2426 opt: 2426 Z-score: 1729.0 bits: 328.4 E(85289): 1.4e-89 Smith-Waterman score: 2426; 99.4% identity (100.0% similar) in 350 aa overlap (1-350:1-350) 10 20 30 40 50 60 pF1KB7 MFCCLGYEWLSGGCKTWHSAWVINTLADHRHRGTDFGGSPWLLIITVFLRSYKFAISLCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFCCLGYEWLSGGCKTWHSAWVINTLADHRHRGTDFGGSPWLLIITVFLRSYKFAISLCT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEGIKIVLEDIFTLWRQVETKVRAK .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEGIKIVLEDIFTLWRQVETKVRAK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHGEKERQVSEAEENGKLDMKEIHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHGEKERQVSEAEENGKLDMKEIHT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 YMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMAAVEHRHSSGLPYWPYLTAETLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMAAVEHRHSSGLPYWPYLTAETLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 NRMGHQPPPPTQQHSIIDNSLSLKTPSECLLTPLPPSALPSADDNLKTPAECLLYPLPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRMGHQPPPPTQQHSIIDNSLSLKTPSECLLTPLPPSALPSADDNLKTPAECLLYPLPPS 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 ADDNLKTPPECLLTPLPPSAPPSADDNLKTPPECVCSLPFHPQRMIISRN :::::::::::::::::::::::.:::::::::::::::::::::::::: XP_011 ADDNLKTPPECLLTPLPPSAPPSVDDNLKTPPECVCSLPFHPQRMIISRN 310 320 330 340 350 >>XP_011521050 (OMIM: 606406) PREDICTED: nuclear pore co (377 aa) initn: 2259 init1: 2259 opt: 2259 Z-score: 1610.9 bits: 306.7 E(85289): 5.5e-83 Smith-Waterman score: 2259; 96.8% identity (98.2% similar) in 342 aa overlap (9-350:36-377) 10 20 30 pF1KB7 MFCCLGYEWLSGGCKTWHSAWVINTLADHRHRGTDFGG :: : . .:. ::::::::::::::::: XP_011 LLFWLLFWLLLGFISHQSTCVSRWVLWLLFWLLLGFISHQSTCVINTLADHRHRGTDFGG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 SPWLLIITVFLRSYKFAISLCTTYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEG ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_011 SPWLLIITVFLRSYKFAISLCTSYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 IKIVLEDIFTLWRQVETKVRAKIRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKIVLEDIFTLWRQVETKVRAKIRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHG 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 EKERQVSEAEENGKLDMKEIHTYMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKERQVSEAEENGKLDMKEIHTYMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 AVEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSIIDNSLSLKTPSECLLTPLPPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSIIDNSLSLKTPSECLLTPLPPSA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 LPSADDNLKTPAECLLYPLPPSADDNLKTPPECLLTPLPPSAPPSADDNLKTPPECVCSL :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: XP_011 LPSADDNLKTPAECLLYPLPPSADDNLKTPPECLLTPLPPSAPPSVDDNLKTPPECVCSL 310 320 330 340 350 360 340 350 pF1KB7 PFHPQRMIISRN :::::::::::: XP_011 PFHPQRMIISRN 370 >>XP_016879380 (OMIM: 606406) PREDICTED: nuclear pore co (232 aa) initn: 1460 init1: 1460 opt: 1460 Z-score: 1050.6 bits: 202.3 E(85289): 8.8e-52 Smith-Waterman score: 1460; 99.5% identity (100.0% similar) in 214 aa overlap (1-214:1-214) 10 20 30 40 50 60 pF1KB7 MFCCLGYEWLSGGCKTWHSAWVINTLADHRHRGTDFGGSPWLLIITVFLRSYKFAISLCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFCCLGYEWLSGGCKTWHSAWVINTLADHRHRGTDFGGSPWLLIITVFLRSYKFAISLCT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEGIKIVLEDIFTLWRQVETKVRAK .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEGIKIVLEDIFTLWRQVETKVRAK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHGEKERQVSEAEENGKLDMKEIHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHGEKERQVSEAEENGKLDMKEIHT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 YMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMAAVEHRHSSGLPYWPYLTAETLK :::::::::::::::::::::::::::::::::: XP_016 YMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRCTYNLVLPGSEKKYYSHA 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 NRMGHQPPPPTQQHSIIDNSLSLKTPSECLLTPLPPSALPSADDNLKTPAECLLYPLPPS >>XP_011521053 (OMIM: 606406) PREDICTED: nuclear pore co (259 aa) initn: 1293 init1: 1293 opt: 1293 Z-score: 932.2 bits: 180.5 E(85289): 3.5e-45 Smith-Waterman score: 1293; 95.1% identity (97.1% similar) in 206 aa overlap (9-214:36-241) 10 20 30 pF1KB7 MFCCLGYEWLSGGCKTWHSAWVINTLADHRHRGTDFGG :: : . .:. ::::::::::::::::: XP_011 LLFWLLFWLLLGFISHQSTCVSRWVLWLLFWLLLGFISHQSTCVINTLADHRHRGTDFGG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 SPWLLIITVFLRSYKFAISLCTTYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEG ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_011 SPWLLIITVFLRSYKFAISLCTSYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 IKIVLEDIFTLWRQVETKVRAKIRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKIVLEDIFTLWRQVETKVRAKIRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHG 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 EKERQVSEAEENGKLDMKEIHTYMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKERQVSEAEENGKLDMKEIHTYMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRCTYN 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 AVEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSIIDNSLSLKTPSECLLTPLPPSA XP_011 LVLPGSEKKYYSHA 250 >>XP_011521052 (OMIM: 606406) PREDICTED: nuclear pore co (341 aa) initn: 2005 init1: 1190 opt: 1206 Z-score: 869.2 bits: 169.3 E(85289): 1.1e-41 Smith-Waterman score: 1937; 86.0% identity (87.7% similar) in 342 aa overlap (9-350:36-341) 10 20 30 pF1KB7 MFCCLGYEWLSGGCKTWHSAWVINTLADHRHRGTDFGG :: : . .:. ::::::::::::::::: XP_011 LLFWLLFWLLLGFISHQSTCVSRWVLWLLFWLLLGFISHQSTCVINTLADHRHRGTDFGG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 SPWLLIITVFLRSYKFAISLCTTYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEG ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_011 SPWLLIITVFLRSYKFAISLCTSYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 IKIVLEDIFTLWRQVETKVRAKIRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHG :::::::::::::::::::::::::::::::::::::::::::::::. XP_011 IKIVLEDIFTLWRQVETKVRAKIRKMKVTTKVNRHDKINGKRKTAKEQ------------ 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 EKERQVSEAEENGKLDMKEIHTYMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMA :::::::::::::::::::::::::::::::::::: XP_011 ------------------------EMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMA 180 190 200 220 230 240 250 260 270 pF1KB7 AVEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSIIDNSLSLKTPSECLLTPLPPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSIIDNSLSLKTPSECLLTPLPPSA 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB7 LPSADDNLKTPAECLLYPLPPSADDNLKTPPECLLTPLPPSAPPSADDNLKTPPECVCSL :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: XP_011 LPSADDNLKTPAECLLYPLPPSADDNLKTPPECLLTPLPPSAPPSVDDNLKTPPECVCSL 270 280 290 300 310 320 340 350 pF1KB7 PFHPQRMIISRN :::::::::::: XP_011 PFHPQRMIISRN 330 340 350 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 09:47:15 2016 done: Sat Nov 5 09:47:16 2016 Total Scan time: 9.120 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]