FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7386, 418 aa 1>>>pF1KB7386 418 - 418 aa - 418 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6337+/-0.00102; mu= 2.3609+/- 0.062 mean_var=165.8740+/-33.260, 0's: 0 Z-trim(110.0): 45 B-trim: 95 in 1/50 Lambda= 0.099583 statistics sampled from 11279 (11313) to 11279 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.688), E-opt: 0.2 (0.348), width: 16 Scan time: 3.220 The best scores are: opt bits E(32554) CCDS5778.1 ING3 gene_id:54556|Hs108|chr7 ( 418) 2744 406.2 3.1e-113 CCDS35497.1 ING3 gene_id:54556|Hs108|chr7 ( 92) 585 95.7 2e-20 CCDS9518.1 ING1 gene_id:3621|Hs108|chr13 ( 210) 408 70.4 1.8e-12 CCDS9515.1 ING1 gene_id:3621|Hs108|chr13 ( 235) 408 70.4 2e-12 CCDS9516.1 ING1 gene_id:3621|Hs108|chr13 ( 279) 408 70.5 2.3e-12 CCDS9517.1 ING1 gene_id:3621|Hs108|chr13 ( 422) 408 70.6 3.3e-12 CCDS44812.1 ING4 gene_id:51147|Hs108|chr12 ( 225) 386 67.3 1.7e-11 CCDS44813.1 ING4 gene_id:51147|Hs108|chr12 ( 249) 386 67.3 1.9e-11 CCDS44814.1 ING4 gene_id:51147|Hs108|chr12 ( 246) 382 66.7 2.8e-11 CCDS8555.1 ING4 gene_id:51147|Hs108|chr12 ( 248) 380 66.4 3.4e-11 CCDS44815.1 ING4 gene_id:51147|Hs108|chr12 ( 245) 378 66.1 4.1e-11 CCDS33425.1 ING5 gene_id:84289|Hs108|chr2 ( 240) 372 65.3 7.3e-11 CCDS3833.1 ING2 gene_id:3622|Hs108|chr4 ( 280) 371 65.2 9.2e-11 >>CCDS5778.1 ING3 gene_id:54556|Hs108|chr7 (418 aa) initn: 2744 init1: 2744 opt: 2744 Z-score: 2146.5 bits: 406.2 E(32554): 3.1e-113 Smith-Waterman score: 2744; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418) 10 20 30 40 50 60 pF1KB7 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 QMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 RRSLELDTPSQPVNNHHAHSHTPVEKRKYNPTSHHTTTDHIPEKKFKSEALLSTLTSDAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 RRSLELDTPSQPVNNHHAHSHTPVEKRKYNPTSHHTTTDHIPEKKFKSEALLSTLTSDAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 KENTLGCRNNNSTASSNNAYNVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 KENTLGCRNNNSTASSNNAYNVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EGRRTSSLKASYEAFKNNDFQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 EGRRTSSLKASYEAFKNNDFQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 KSKNNNKSSSQQSSSSSSSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 KSKNNNKSSSQQSSSSSSSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEP 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK 370 380 390 400 410 >>CCDS35497.1 ING3 gene_id:54556|Hs108|chr7 (92 aa) initn: 585 init1: 585 opt: 585 Z-score: 480.3 bits: 95.7 E(32554): 2e-20 Smith-Waterman score: 585; 100.0% identity (100.0% similar) in 89 aa overlap (1-89:1-89) 10 20 30 40 50 60 pF1KB7 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE ::::::::::::::::::::::::::::: CCDS35 QMASIKKDYYKALEDADEKVQLANQIYDLQHF 70 80 90 >>CCDS9518.1 ING1 gene_id:3621|Hs108|chr13 (210 aa) initn: 448 init1: 379 opt: 408 Z-score: 337.4 bits: 70.4 E(32554): 1.8e-12 Smith-Waterman score: 408; 35.2% identity (69.3% similar) in 179 aa overlap (231-406:18-187) 210 220 230 240 250 pF1KB7 NVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMKE--GRRTSSLKASYEAFKNN . .: ..:: : :: .. . : :. . CCDS95 MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQ 10 20 30 40 260 270 280 290 300 310 pF1KB7 DFQLGKEFSMARETVGYSSSS-ALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSS . .:: .:.: :... : :... .:. .:...::.. . .:. . CCDS95 Q-ELG-------DTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDH 50 60 70 80 90 320 330 340 350 360 370 pF1KB7 SSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCD .... .. . ... ... .... . : .. : .: ::::: ::.:::::::::.::: CCDS95 DDGASGTPKEKKAKTSKKKKRSKAKAEREA-SPADLPIDPNEPTYCLCNQVSYGEMIGCD 100 110 120 130 140 150 380 390 400 410 pF1KB7 NQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK :..:::::::..::::.. ::::::::.: CCDS95 NDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR 160 170 180 190 200 210 >>CCDS9515.1 ING1 gene_id:3621|Hs108|chr13 (235 aa) initn: 448 init1: 379 opt: 408 Z-score: 336.6 bits: 70.4 E(32554): 2e-12 Smith-Waterman score: 408; 35.2% identity (69.3% similar) in 179 aa overlap (231-406:43-212) 210 220 230 240 250 pF1KB7 NVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMKE--GRRTSSLKASYEAFKNN . .: ..:: : :: .. . : :. . CCDS95 RFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQ 20 30 40 50 60 70 260 270 280 290 300 310 pF1KB7 DFQLGKEFSMARETVGYSSSS-ALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSS . .:: .:.: :... : :... .:. .:...::.. . .:. . CCDS95 Q-ELG-------DTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDH 80 90 100 110 120 320 330 340 350 360 370 pF1KB7 SSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCD .... .. . ... ... .... . : .. : .: ::::: ::.:::::::::.::: CCDS95 DDGASGTPKEKKAKTSKKKKRSKAKAEREA-SPADLPIDPNEPTYCLCNQVSYGEMIGCD 130 140 150 160 170 180 380 390 400 410 pF1KB7 NQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK :..:::::::..::::.. ::::::::.: CCDS95 NDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR 190 200 210 220 230 >>CCDS9516.1 ING1 gene_id:3621|Hs108|chr13 (279 aa) initn: 544 init1: 379 opt: 408 Z-score: 335.4 bits: 70.5 E(32554): 2.3e-12 Smith-Waterman score: 408; 35.2% identity (69.3% similar) in 179 aa overlap (231-406:87-256) 210 220 230 240 250 pF1KB7 NVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMKE--GRRTSSLKASYEAFKNN . .: ..:: : :: .. . : :. . CCDS95 RFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQ 60 70 80 90 100 110 260 270 280 290 300 310 pF1KB7 DFQLGKEFSMARETVGYSSSS-ALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSS . .:: .:.: :... : :... .:. .:...::.. . .:. . CCDS95 Q-ELG-------DTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDH 120 130 140 150 160 320 330 340 350 360 370 pF1KB7 SSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCD .... .. . ... ... .... . : .. : .: ::::: ::.:::::::::.::: CCDS95 DDGASGTPKEKKAKTSKKKKRSKAKAEREA-SPADLPIDPNEPTYCLCNQVSYGEMIGCD 170 180 190 200 210 220 380 390 400 410 pF1KB7 NQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK :..:::::::..::::.. ::::::::.: CCDS95 NDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR 230 240 250 260 270 >>CCDS9517.1 ING1 gene_id:3621|Hs108|chr13 (422 aa) initn: 448 init1: 379 opt: 408 Z-score: 332.7 bits: 70.6 E(32554): 3.3e-12 Smith-Waterman score: 408; 35.2% identity (69.3% similar) in 179 aa overlap (231-406:230-399) 210 220 230 240 250 pF1KB7 NVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMKE--GRRTSSLKASYEAFKNN . .: ..:: : :: .. . : :. . CCDS95 RFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQ 200 210 220 230 240 250 260 270 280 290 300 310 pF1KB7 DFQLGKEFSMARETVGYSSSS-ALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSS . .:: .:.: :... : :... .:. .:...::.. . .:. . CCDS95 Q-ELG-------DTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDH 260 270 280 290 300 310 320 330 340 350 360 370 pF1KB7 SSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCD .... .. . ... ... .... . : .. : .: ::::: ::.:::::::::.::: CCDS95 DDGASGTPKEKKAKTSKKKKRSKAKAEREA-SPADLPIDPNEPTYCLCNQVSYGEMIGCD 320 330 340 350 360 370 380 390 400 410 pF1KB7 NQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK :..:::::::..::::.. ::::::::.: CCDS95 NDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR 380 390 400 410 420 >>CCDS44812.1 ING4 gene_id:51147|Hs108|chr12 (225 aa) initn: 489 init1: 357 opt: 386 Z-score: 319.8 bits: 67.3 E(32554): 1.7e-11 Smith-Waterman score: 386; 38.6% identity (73.2% similar) in 127 aa overlap (290-413:99-225) 260 270 280 290 300 310 pF1KB7 FQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSSSS :::. ...:: .:... . .......:. CCDS44 VDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDE 70 80 90 100 110 120 320 330 340 350 360 370 pF1KB7 SSLSSCSSSSTVVQ---EISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGC . .. ... .:. : .. ... .. .: ::::: ::.:.:::::::.:: CCDS44 EAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGC 130 140 150 160 170 180 380 390 400 410 pF1KB7 DNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK :: :: :::::..::::: :.:::.::.:. :.. CCDS44 DNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK 190 200 210 220 >>CCDS44813.1 ING4 gene_id:51147|Hs108|chr12 (249 aa) initn: 604 init1: 357 opt: 386 Z-score: 319.1 bits: 67.3 E(32554): 1.9e-11 Smith-Waterman score: 386; 38.6% identity (73.2% similar) in 127 aa overlap (290-413:123-249) 260 270 280 290 300 310 pF1KB7 FQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSSSS :::. ...:: .:... . .......:. CCDS44 VDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDE 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB7 SSLSSCSSSSTVVQ---EISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGC . .. ... .:. : .. ... .. .: ::::: ::.:.:::::::.:: CCDS44 EAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGC 160 170 180 190 200 210 380 390 400 410 pF1KB7 DNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK :: :: :::::..::::: :.:::.::.:. :.. CCDS44 DNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK 220 230 240 >>CCDS44814.1 ING4 gene_id:51147|Hs108|chr12 (246 aa) initn: 623 init1: 357 opt: 382 Z-score: 316.1 bits: 66.7 E(32554): 2.8e-11 Smith-Waterman score: 382; 38.7% identity (68.5% similar) in 124 aa overlap (290-413:123-246) 260 270 280 290 300 310 pF1KB7 FQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSSSS :::. ..:. ...: :. ..:. . CCDS44 VDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKEGRTQKEKKAARARSKGKNSDEEAP 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB7 SSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQ .. .. . . : .. ... .. .: ::::: ::.:.:::::::.:::: CCDS44 KTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNP 160 170 180 190 200 210 380 390 400 410 pF1KB7 DCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK :: :::::..::::: :.:::.::.:. :.. CCDS44 DCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK 220 230 240 >>CCDS8555.1 ING4 gene_id:51147|Hs108|chr12 (248 aa) initn: 625 init1: 357 opt: 380 Z-score: 314.5 bits: 66.4 E(32554): 3.4e-11 Smith-Waterman score: 380; 38.1% identity (68.3% similar) in 126 aa overlap (288-413:123-248) 260 270 280 290 300 310 pF1KB7 NDFQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSS ..::.. ::. ...: :. ..:. CCDS85 VDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKSRTQKEKKAARARSKGKNSDEE 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB7 SSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCD . .. .. . . : .. ... .. .: ::::: ::.:.:::::::.::: CCDS85 APKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCD 160 170 180 190 200 210 380 390 400 410 pF1KB7 NQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK : :: :::::..::::: :.:::.::.:. :.. CCDS85 NPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK 220 230 240 418 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 07:06:24 2016 done: Fri Nov 4 07:06:24 2016 Total Scan time: 3.220 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]