FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7408, 394 aa 1>>>pF1KB7408 394 - 394 aa - 394 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4520+/-0.000578; mu= 11.6259+/- 0.035 mean_var=201.8934+/-41.635, 0's: 0 Z-trim(113.2): 588 B-trim: 683 in 1/51 Lambda= 0.090264 statistics sampled from 21711 (22445) to 21711 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.263), width: 16 Scan time: 7.400 The best scores are: opt bits E(85289) XP_016859648 (OMIM: 608914) PREDICTED: POTE ankyri ( 967) 2674 362.2 3e-99 XP_016855045 (OMIM: 608912) PREDICTED: LOW QUALITY ( 546) 1907 262.0 2.5e-69 XP_011509518 (OMIM: 608914) PREDICTED: POTE ankyri ( 957) 1544 215.1 5.8e-55 NP_001077007 (OMIM: 608914) POTE ankyrin domain fa (1075) 1544 215.1 6.2e-55 XP_016859650 (OMIM: 608914) PREDICTED: POTE ankyri (1075) 1544 215.1 6.2e-55 NP_001005356 (OMIM: 608916) POTE ankyrin domain fa ( 508) 1382 193.6 9e-49 XP_011527852 (OMIM: 607549) PREDICTED: POTE ankyri ( 376) 1317 184.9 2.7e-46 XP_006724060 (OMIM: 607549) PREDICTED: POTE ankyri ( 384) 1317 185.0 2.7e-46 NP_001129685 (OMIM: 608913) POTE ankyrin domain fa ( 545) 1318 185.3 3e-46 NP_778146 (OMIM: 607549) POTE ankyrin domain famil ( 584) 1317 185.2 3.5e-46 XP_011542096 (OMIM: 608912) PREDICTED: POTE ankyri ( 339) 1068 152.5 1.5e-36 XP_016877347 (OMIM: 608912) PREDICTED: POTE ankyri ( 339) 1068 152.5 1.5e-36 XP_006720418 (OMIM: 608912) PREDICTED: POTE ankyri ( 347) 1068 152.5 1.5e-36 NP_001264233 (OMIM: 608912) POTE ankyrin domain fa ( 544) 1068 152.7 1.9e-36 XP_011542818 (OMIM: 608915) PREDICTED: POTE ankyri ( 310) 922 133.4 7.3e-31 NP_001005365 (OMIM: 608915) POTE ankyrin domain fa ( 498) 894 130.0 1.2e-29 NP_001002920 (OMIM: 608915) POTE ankyrin domain fa ( 452) 695 104.1 7.2e-22 XP_011523968 (OMIM: 616565) PREDICTED: ankyrin rep ( 850) 481 76.6 2.5e-13 XP_011518060 (OMIM: 610856) PREDICTED: ankyrin rep (1192) 483 77.0 2.6e-13 NP_443723 (OMIM: 610856) ankyrin repeat domain-con (1341) 483 77.1 2.8e-13 XP_011523967 (OMIM: 616565) PREDICTED: ankyrin rep (1076) 481 76.7 2.9e-13 XP_011523966 (OMIM: 616565) PREDICTED: ankyrin rep (1149) 481 76.7 3e-13 XP_011518059 (OMIM: 610856) PREDICTED: ankyrin rep (1585) 483 77.2 3.1e-13 NP_001138501 (OMIM: 616565) ankyrin repeat domain- (1392) 481 76.9 3.4e-13 XP_006722388 (OMIM: 616565) PREDICTED: ankyrin rep (1511) 481 76.9 3.6e-13 XP_011523964 (OMIM: 616565) PREDICTED: ankyrin rep (1525) 481 76.9 3.6e-13 XP_016871423 (OMIM: 188000,610855) PREDICTED: anky (1037) 414 68.0 1.2e-10 XP_016871422 (OMIM: 188000,610855) PREDICTED: anky (1656) 414 68.2 1.6e-10 NP_001242982 (OMIM: 188000,610855) ankyrin repeat (1709) 414 68.3 1.6e-10 NP_055730 (OMIM: 188000,610855) ankyrin repeat dom (1710) 414 68.3 1.6e-10 XP_016871421 (OMIM: 188000,610855) PREDICTED: anky (2031) 414 68.4 1.8e-10 XP_006717488 (OMIM: 188000,610855) PREDICTED: anky (2031) 414 68.4 1.8e-10 XP_016871419 (OMIM: 188000,610855) PREDICTED: anky (2062) 414 68.4 1.8e-10 XP_011517718 (OMIM: 188000,610855) PREDICTED: anky (2062) 414 68.4 1.8e-10 XP_016871420 (OMIM: 188000,610855) PREDICTED: anky (2062) 414 68.4 1.8e-10 XP_006717486 (OMIM: 188000,610855) PREDICTED: anky (2072) 414 68.4 1.8e-10 XP_016871418 (OMIM: 188000,610855) PREDICTED: anky (2108) 414 68.4 1.8e-10 XP_016871417 (OMIM: 188000,610855) PREDICTED: anky (2112) 414 68.4 1.8e-10 NP_062618 (OMIM: 610731) ankyrin repeat domain-con ( 254) 365 60.7 4.4e-09 XP_006719577 (OMIM: 607815) PREDICTED: ankyrin rep (1184) 259 47.9 0.00016 XP_016875147 (OMIM: 607815) PREDICTED: ankyrin rep (1188) 259 47.9 0.00016 XP_006719576 (OMIM: 607815) PREDICTED: ankyrin rep (1199) 259 47.9 0.00016 XP_006719575 (OMIM: 607815) PREDICTED: ankyrin rep (1200) 259 47.9 0.00016 XP_016875146 (OMIM: 607815) PREDICTED: ankyrin rep (1226) 259 47.9 0.00016 XP_006719573 (OMIM: 607815) PREDICTED: ankyrin rep (1235) 259 47.9 0.00016 NP_690001 (OMIM: 607815) ankyrin repeat and steril (1248) 259 47.9 0.00016 XP_016875145 (OMIM: 607815) PREDICTED: ankyrin rep (1250) 259 47.9 0.00016 XP_011536873 (OMIM: 607815) PREDICTED: ankyrin rep (1251) 259 47.9 0.00016 XP_005269086 (OMIM: 607815) PREDICTED: ankyrin rep (1256) 259 47.9 0.00016 XP_016875144 (OMIM: 607815) PREDICTED: ankyrin rep (1259) 259 47.9 0.00016 >>XP_016859648 (OMIM: 608914) PREDICTED: POTE ankyrin do (967 aa) initn: 2674 init1: 2674 opt: 2674 Z-score: 1902.9 bits: 362.2 E(85289): 3e-99 Smith-Waterman score: 2674; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386) 10 20 30 40 50 60 pF1KB7 MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIKVCSSQLYQHEAVQCQEDECALMLLEHGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIKVCSSQLYQHEAVQCQEDECALMLLEHGT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 DPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHH 310 320 330 340 350 360 370 380 390 pF1KB7 HVICQLLSDYKEKQMLKISSENSNPENVSRTRNK :::::::::::::::::::::::::: XP_016 HVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKD 370 380 390 400 410 420 >>XP_016855045 (OMIM: 608912) PREDICTED: LOW QUALITY PRO (546 aa) initn: 1925 init1: 995 opt: 1907 Z-score: 1365.7 bits: 262.0 E(85289): 2.5e-69 Smith-Waterman score: 2025; 81.2% identity (85.1% similar) in 388 aa overlap (1-386:1-341) 10 20 30 40 50 60 pF1KB7 MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK ::.:: ::::::.::::: ::::::::: XP_016 MVAEVCSMPAASAVKKPFDLRSKMGKWC-------------------------------- 10 20 70 80 90 100 110 120 pF1KB7 MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW :: :::::::::::::.::::::: :::::.:::::::::::::::::::.::.: XP_016 -----HHRFPCCRGSGKSNVGTSGDHDDSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTW 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB7 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA :::::::::::::::: ::::::::::::::::::::::::::::.::.::::::::::: XP_016 GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA 90 100 110 120 130 140 190 200 210 220 230 pF1KB7 SANGNSEVVKLLL--DRRCQLNVLDNKKRTALIKVCSSQLYQHEAVQCQEDECALMLLEH :::::::::.::: ::::::::::::::::::: :::::::::.:::::: XP_016 SANGNSEVVQLLLLLDRRCQLNVLDNKKRTALIK----------AVQCQEDECVLMLLEH 150 160 170 180 190 240 250 260 270 280 290 pF1KB7 GTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVV :.: :: ::::::.::::::: :::::::::::::::::::: ::::::::::::::::: XP_016 GADGNIQDEYGNTALHYAIYNGDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVV 200 210 220 230 240 250 300 310 320 330 340 350 pF1KB7 KFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSS :::::::::::::::::::::::::::::::::.::::::.::::::::::::::::::: XP_016 KFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSS 260 270 280 290 300 310 360 370 380 390 pF1KB7 HHHVICQLLSDYKEKQMLKISSENSNPENVSRTRNK ::::::.::::::::::::::::::::: XP_016 HHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEIN 320 330 340 350 360 370 >>XP_011509518 (OMIM: 608914) PREDICTED: POTE ankyrin do (957 aa) initn: 1667 init1: 1544 opt: 1544 Z-score: 1107.7 bits: 215.1 E(85289): 5.8e-55 Smith-Waterman score: 2573; 97.4% identity (97.4% similar) in 386 aa overlap (1-386:1-376) 10 20 30 40 50 60 pF1KB7 MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIKVCSSQLYQHEAVQCQEDECALMLLEHGT :::::::::::::::::::::::::::::::: :::::::::::::::::: XP_011 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIK----------AVQCQEDECALMLLEHGT 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 DPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKF 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 LIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHH 300 310 320 330 340 350 370 380 390 pF1KB7 HVICQLLSDYKEKQMLKISSENSNPENVSRTRNK :::::::::::::::::::::::::: XP_011 HVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKD 360 370 380 390 400 410 >>NP_001077007 (OMIM: 608914) POTE ankyrin domain family (1075 aa) initn: 1801 init1: 1544 opt: 1544 Z-score: 1107.2 bits: 215.1 E(85289): 6.2e-55 Smith-Waterman score: 2573; 97.4% identity (97.4% similar) in 386 aa overlap (1-386:1-376) 10 20 30 40 50 60 pF1KB7 MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIKVCSSQLYQHEAVQCQEDECALMLLEHGT :::::::::::::::::::::::::::::::: :::::::::::::::::: NP_001 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIK----------AVQCQEDECALMLLEHGT 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 DPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKF 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 LIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHH 300 310 320 330 340 350 370 380 390 pF1KB7 HVICQLLSDYKEKQMLKISSENSNPENVSRTRNK :::::::::::::::::::::::::: NP_001 HVICQLLSDYKEKQMLKISSENSNPEQELKLTSEEESQRFKGSENSQPEKMSQELEINKD 360 370 380 390 400 410 >>XP_016859650 (OMIM: 608914) PREDICTED: POTE ankyrin do (1075 aa) initn: 1801 init1: 1544 opt: 1544 Z-score: 1107.2 bits: 215.1 E(85289): 6.2e-55 Smith-Waterman score: 2573; 97.4% identity (97.4% similar) in 386 aa overlap (1-386:1-376) 10 20 30 40 50 60 pF1KB7 MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIKVCSSQLYQHEAVQCQEDECALMLLEHGT :::::::::::::::::::::::::::::::: :::::::::::::::::: XP_016 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIK----------AVQCQEDECALMLLEHGT 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 DPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKF 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 LIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHH 300 310 320 330 340 350 370 380 390 pF1KB7 HVICQLLSDYKEKQMLKISSENSNPENVSRTRNK :::::::::::::::::::::::::: XP_016 HVICQLLSDYKEKQMLKISSENSNPEQELKLTSEEESQRFKGSENSQPEKMSQELEINKD 360 370 380 390 400 410 >>NP_001005356 (OMIM: 608916) POTE ankyrin domain family (508 aa) initn: 1499 init1: 1379 opt: 1382 Z-score: 996.6 bits: 193.6 E(85289): 9e-49 Smith-Waterman score: 2392; 91.5% identity (95.1% similar) in 386 aa overlap (1-386:1-376) 10 20 30 40 50 60 pF1KB7 MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK ::.:. :::::::::::::::::::::: .::: : ::::::::::::::::::::::: NP_001 MVAEAGSMPAASSVKKPFGLRSKMGKWCRHCFPWCRGSGKSNVGTSGDHDDSAMKTLRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW :::::.:::: ::::.:::::.:::::::::::::.:::::::::::::::::::::: : NP_001 MGKWCRHCFPWCRGSSKSNVGTSGDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKSKVGPW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA :::::::::::::::: ::::::::::::::::::::::::.:::.:::::::::::::: NP_001 GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIKVCSSQLYQHEAVQCQEDECALMLLEHGT ::::::::::::::::::::.::::::::: : ::::.::::::::::::: NP_001 SANGNSEVVKLLLDRRCQLNILDNKKRTALTK----------AVQCREDECALMLLEHGT 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 DPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKF :::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKF 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 LIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHH 300 310 320 330 340 350 370 380 390 pF1KB7 HVICQLLSDYKEKQMLKISSENSNPENVSRTRNK .::::::::::::::::.:::::::: NP_001 NVICQLLSDYKEKQMLKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEEMSQEPEINKG 360 370 380 390 400 410 >>XP_011527852 (OMIM: 607549) PREDICTED: POTE ankyrin do (376 aa) initn: 1442 init1: 1314 opt: 1317 Z-score: 952.2 bits: 184.9 E(85289): 2.7e-46 Smith-Waterman score: 2281; 87.0% identity (93.2% similar) in 385 aa overlap (1-385:1-375) 10 20 30 40 50 60 pF1KB7 MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK ::.:: :::.::.::::: ::::::::: . ::: : :::::.::::::::: :: :::: XP_011 MVAEVCSMPTASTVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKMLRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW ::: :.:::::::::: ::::.::::..: :: ::.:::::::::::::::::::.:::: XP_011 MGKCCRHCFPCCRGSGTSNVGTSGDHENSFMKMLRSKMGKWCCHCFPCCRGSGKSNVGAW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA :::: :::::::::.: ::::::::::::::::::::::::::::.::.::.:::::::: XP_011 GDYDHSAFMEPRYHIRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIKVCSSQLYQHEAVQCQEDECALMLLEHGT :::::::::.:::::::::::::::::::::: :.:::::::.:::::::. XP_011 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIK----------AIQCQEDECVLMLLEHGA 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 DPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKF : :::::::::.:::::::::::::::::::::::::::: ::::::::::::::::::: XP_011 DRNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKF 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 LIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHH :::::::::.:::::::::::::::::::::.::::::.::::::::::::::::::::: XP_011 LIKKKANLNVLDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHH 300 310 320 330 340 350 370 380 390 pF1KB7 HVICQLLSDYKEKQMLKISSENSNPENVSRTRNK ::::.:::::::::::::::::::: XP_011 HVICELLSDYKEKQMLKISSENSNPV 360 370 >>XP_006724060 (OMIM: 607549) PREDICTED: POTE ankyrin do (384 aa) initn: 1442 init1: 1314 opt: 1317 Z-score: 952.1 bits: 185.0 E(85289): 2.7e-46 Smith-Waterman score: 2336; 87.3% identity (93.4% similar) in 394 aa overlap (1-394:1-384) 10 20 30 40 50 60 pF1KB7 MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK ::.:: :::.::.::::: ::::::::: . ::: : :::::.::::::::: :: :::: XP_006 MVAEVCSMPTASTVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKMLRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW ::: :.:::::::::: ::::.::::..: :: ::.:::::::::::::::::::.:::: XP_006 MGKCCRHCFPCCRGSGTSNVGTSGDHENSFMKMLRSKMGKWCCHCFPCCRGSGKSNVGAW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA :::: :::::::::.: ::::::::::::::::::::::::::::.::.::.:::::::: XP_006 GDYDHSAFMEPRYHIRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIKVCSSQLYQHEAVQCQEDECALMLLEHGT :::::::::.:::::::::::::::::::::: :.:::::::.:::::::. XP_006 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIK----------AIQCQEDECVLMLLEHGA 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 DPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKF : :::::::::.:::::::::::::::::::::::::::: ::::::::::::::::::: XP_006 DRNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKF 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 LIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHH :::::::::.:::::::::::::::::::::.::::::.::::::::::::::::::::: XP_006 LIKKKANLNVLDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHH 300 310 320 330 340 350 370 380 390 pF1KB7 HVICQLLSDYKEKQMLKISSENSNPENVSRTRNK ::::.::::::::::::::::::::::::::::: XP_006 HVICELLSDYKEKQMLKISSENSNPENVSRTRNK 360 370 380 >>NP_001129685 (OMIM: 608913) POTE ankyrin domain family (545 aa) initn: 1823 init1: 1318 opt: 1318 Z-score: 951.2 bits: 185.3 E(85289): 3e-46 Smith-Waterman score: 2318; 84.2% identity (87.1% similar) in 417 aa overlap (7-386:7-413) 10 20 pF1KB7 MVVEVDSMPAASSVKKPFGLRSKMGKWC-------------------------------- :::::::::::::::::::::: NP_001 MVAEAGSMPAASSVKKPFGLRSKMGKWCRHCFAWCRGSGKSNVGTSGDHDDSAMKTLRSK 10 20 30 40 50 60 30 40 50 60 70 80 pF1KB7 -----CRCFPCYRESGKSNVGTSGDHDDSAMKTLRSKMGKWCHHCFPCCRGSGKSNVGAS :.::: : :::::::::::::::::::::::::::: :::::::::::::::.: NP_001 MGKWCCHCFPWCRGSGKSNVGTSGDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKSNVGTS 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB7 GDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAWGDYDDSAFMEPRYHVRGEDLDKL ::::::::::::.::::::::::::::::::.::: ::::::::::::::::: :::::: NP_001 GDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKNKVGPWGDYDDSAFMEPRYHVRREDLDKL 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB7 HRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLD ::::::::::::::::::.:::.::::::::::::::::::::::::::::::::::.:: NP_001 HRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNILD 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB7 NKKRTALIKVCSSQLYQHEAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKL ::::::: : :::::::::::::::::::::::::::::.::::::::::: NP_001 NKKRTALTK----------AVQCQEDECALMLLEHGTDPNIPDEYGNTALHYAIYNEDKL 250 260 270 280 290 270 280 290 300 310 320 pF1KB7 MAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAV 300 310 320 330 340 350 330 340 350 360 370 380 pF1KB7 CCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENS :::::::::::::::::::::::::::::::::::.:.:::::::::::::.::.::::: NP_001 CCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSDYKEKQILKVSSENS 360 370 380 390 400 410 390 pF1KB7 NPENVSRTRNK ::: NP_001 NPEQDLKLTSEEESQRLKGSENSQPEEMSQEPEINKGGDRKVEEEMKKHGSTHMGFPENL 420 430 440 450 460 470 >>NP_778146 (OMIM: 607549) POTE ankyrin domain family me (584 aa) initn: 1442 init1: 1314 opt: 1317 Z-score: 950.2 bits: 185.2 E(85289): 3.5e-46 Smith-Waterman score: 2287; 87.0% identity (93.3% similar) in 386 aa overlap (1-386:1-376) 10 20 30 40 50 60 pF1KB7 MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK ::.:: :::.::.::::: ::::::::: . ::: : :::::.::::::::: :: :::: NP_778 MVAEVCSMPTASTVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKMLRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW ::: :.:::::::::: ::::.::::..: :: ::.:::::::::::::::::::.:::: NP_778 MGKCCRHCFPCCRGSGTSNVGTSGDHENSFMKMLRSKMGKWCCHCFPCCRGSGKSNVGAW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA :::: :::::::::.: ::::::::::::::::::::::::::::.::.::.:::::::: NP_778 GDYDHSAFMEPRYHIRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIKVCSSQLYQHEAVQCQEDECALMLLEHGT :::::::::.:::::::::::::::::::::: :.:::::::.:::::::. NP_778 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIK----------AIQCQEDECVLMLLEHGA 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 DPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKF : :::::::::.:::::::::::::::::::::::::::: ::::::::::::::::::: NP_778 DRNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKF 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 LIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHH :::::::::.:::::::::::::::::::::.::::::.::::::::::::::::::::: NP_778 LIKKKANLNVLDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHH 300 310 320 330 340 350 370 380 390 pF1KB7 HVICQLLSDYKEKQMLKISSENSNPENVSRTRNK ::::.::::::::::::::::::::: NP_778 HVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKD 360 370 380 390 400 410 394 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 07:30:27 2016 done: Fri Nov 4 07:30:29 2016 Total Scan time: 7.400 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]