FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7415, 321 aa 1>>>pF1KB7415 321 - 321 aa - 321 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2117+/-0.000863; mu= 16.2904+/- 0.052 mean_var=61.3705+/-12.023, 0's: 0 Z-trim(105.8): 14 B-trim: 0 in 0/49 Lambda= 0.163717 statistics sampled from 8611 (8617) to 8611 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.265), width: 16 Scan time: 2.500 The best scores are: opt bits E(32554) CCDS34150.1 PLCXD3 gene_id:345557|Hs108|chr5 ( 321) 2141 514.1 5.7e-146 CCDS2961.1 PLCXD2 gene_id:257068|Hs108|chr3 ( 304) 1064 259.7 2e-69 CCDS54619.1 PLCXD2 gene_id:257068|Hs108|chr3 ( 305) 1057 258.1 6.4e-69 CCDS14103.1 PLCXD1 gene_id:55344|Hs108|chrY ( 323) 604 151.1 1.1e-36 CCDS14103.1 PLCXD1 gene_id:55344|Hs108|chrX ( 323) 604 151.1 1.1e-36 >>CCDS34150.1 PLCXD3 gene_id:345557|Hs108|chr5 (321 aa) initn: 2141 init1: 2141 opt: 2141 Z-score: 2734.2 bits: 514.1 E(32554): 5.7e-146 Smith-Waterman score: 2141; 100.0% identity (100.0% similar) in 321 aa overlap (1-321:1-321) 10 20 30 40 50 60 pF1KB7 MASSQGKNELKLADWMATLPESMHSIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MASSQGKNELKLADWMATLPESMHSIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FVSVFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 FVSVFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFAQEVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 VNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFAQEVS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQASITERRKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQASITERRKKG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 SFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWVRTQKPGESGINIVTADFVEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWVRTQKPGESGINIVTADFVEL 250 260 270 280 290 300 310 320 pF1KB7 GDFISTVIKLNYVFDEGEANT ::::::::::::::::::::: CCDS34 GDFISTVIKLNYVFDEGEANT 310 320 >>CCDS2961.1 PLCXD2 gene_id:257068|Hs108|chr3 (304 aa) initn: 1057 init1: 822 opt: 1064 Z-score: 1359.7 bits: 259.7 E(32554): 2e-69 Smith-Waterman score: 1064; 51.9% identity (84.4% similar) in 270 aa overlap (2-271:22-289) 10 20 30 40 pF1KB7 MASSQGKNELKLADWMATLPESMHSIPLTNLAIPGSHDSF .... ..:. :::::.:: .:..::.::::::::::: CCDS29 MLAVRKARRKLRMGTICSPNPSGTKTSSEVCNADWMASLPPHLHNLPLSNLAIPGSHDSF 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 SFYIDEASPVGPEQPETVQNFVSVFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRIS :...:: :::::.: .... .. . ...::::.:: .::...: :: :::::::::.: CCDS29 SYWVDEKSPVGPDQTQAIKRLARI--SLVKKLMKKWSVTQNLTFREQLEAGIRYFDLRVS 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 TKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQ .:: : :.:.:: ::::. :: .:: ::..:::.: .:..::::::::.:.. ::. :: CCDS29 SKPGDADQEIYFIHGLFGIKVWDGLMEIDSFLTQHPQEIIFLDFNHFYAMDETHHKCLVL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 MLKDIYGNKMCPAIFAQEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTT ... .:::.::: .. ..:. ::::. :::.::: : . ::::::. .:::::::: CCDS29 RIQEAFGNKLCPACSVESLTLRTLWEKNCQVLIFYHCPFYKQYPFLWPGKKIPAPWANTT 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 DPEKLIQFLQASITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWV . .::: ::.....:: ..::: .::..:::...:...:...::..:...: CCDS29 SVRKLILFLETTLSERASRGSFHVSQAILTPRVKTIARGLVGGLKNTLVHRLALIPVYPL 240 250 260 270 280 290 290 300 310 320 pF1KB7 RTQKPGESGINIVTADFVELGDFISTVIKLNYVFDEGEANT CCDS29 RFSRRS 300 >>CCDS54619.1 PLCXD2 gene_id:257068|Hs108|chr3 (305 aa) initn: 1050 init1: 815 opt: 1057 Z-score: 1350.8 bits: 258.1 E(32554): 6.4e-69 Smith-Waterman score: 1057; 52.1% identity (84.3% similar) in 267 aa overlap (2-268:22-286) 10 20 30 40 pF1KB7 MASSQGKNELKLADWMATLPESMHSIPLTNLAIPGSHDSF .... ..:. :::::.:: .:..::.::::::::::: CCDS54 MLAVRKARRKLRMGTICSPNPSGTKTSSEVCNADWMASLPPHLHNLPLSNLAIPGSHDSF 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 SFYIDEASPVGPEQPETVQNFVSVFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRIS :...:: :::::.: .... .. . ...::::.:: .::...: :: :::::::::.: CCDS54 SYWVDEKSPVGPDQTQAIKRLARI--SLVKKLMKKWSVTQNLTFREQLEAGIRYFDLRVS 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 TKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQ .:: : :.:.:: ::::. :: .:: ::..:::.: .:..::::::::.:.. ::. :: CCDS54 SKPGDADQEIYFIHGLFGIKVWDGLMEIDSFLTQHPQEIIFLDFNHFYAMDETHHKCLVL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 MLKDIYGNKMCPAIFAQEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTT ... .:::.::: .. ..:. ::::. :::.::: : . ::::::. .:::::::: CCDS54 RIQEAFGNKLCPACSVESLTLRTLWEKNCQVLIFYHCPFYKQYPFLWPGKKIPAPWANTT 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 DPEKLIQFLQASITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWV . .::: ::.....:: ..::: .::..:::...:...:...::..:. CCDS54 SVRKLILFLETTLSERASRGSFHVSQAILTPRVKTIARGLVGGLKNTLVHSNRWNSHGPS 240 250 260 270 280 290 290 300 310 320 pF1KB7 RTQKPGESGINIVTADFVELGDFISTVIKLNYVFDEGEANT CCDS54 LLSQERS 300 >>CCDS14103.1 PLCXD1 gene_id:55344|Hs108|chrY (323 aa) initn: 364 init1: 267 opt: 604 Z-score: 772.1 bits: 151.1 E(32554): 1.1e-36 Smith-Waterman score: 604; 33.8% identity (65.9% similar) in 302 aa overlap (14-311:22-317) 10 20 30 40 50 pF1KB7 MASSQGKNELKLADWMATLPESMHSIPLTNLAIPGSHDSFSFYIDEASPVGP :::..: . ..:: .:.::::::.... ... ::.. CCDS14 MGGQVSASNSFSRLHCRNANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 EQPETVQNFVSVFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYF :. . .: . ... ... .. :: .::... : :: ::.::.::::. . ...:.: CCDS14 EESRLLQLLNKALPCITRPVVLKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKNLHF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 AHGLFS-AKVNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQMLKDIYGNKMC .: ... : :.. : ::. .: : .:::.: .: :... :: :: .:.:.:. .: CCDS14 VHMVYTTALVEDTLTEISEWLERHPREVVILACRNFEGLSEDLHEYLVACIKNIFGDMLC 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 PAIFAQEVSLKYLWEKDYQVLVFYHSPVALEVPF-LWPGQMMPAPWANTTDPEKLIQFLQ : .. .:. :: . ::.: :.. .:. :::: .: :.: . : ::..:. CCDS14 PR--GEVPTLRQLWSRGQQVIVSYEDESSLRRHHELWPG--VPYWWGNRVKTEALIRYLE 190 200 210 220 230 240 250 260 270 280 pF1KB7 ASITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWVRTQKPGESG- .. . :..:.. . :: . . :. . .: : .: :: . ::: : :: .. CCDS14 -TMKSCGRPGGLFVAGINLTENLQYVLAHPSESL-EKMTLPNLPRLSAWVREQCPGPGSR 240 250 260 270 280 290 290 300 310 320 pF1KB7 -INIVTADFVELGDFISTVIKLNYVFDEGEANT ::...::. :.: :: :: CCDS14 CTNIIAGDFIGADGFVSDVIALNQKLLWC 300 310 320 >>CCDS14103.1 PLCXD1 gene_id:55344|Hs108|chrX (323 aa) initn: 364 init1: 267 opt: 604 Z-score: 772.1 bits: 151.1 E(32554): 1.1e-36 Smith-Waterman score: 604; 33.8% identity (65.9% similar) in 302 aa overlap (14-311:22-317) 10 20 30 40 50 pF1KB7 MASSQGKNELKLADWMATLPESMHSIPLTNLAIPGSHDSFSFYIDEASPVGP :::..: . ..:: .:.::::::.... ... ::.. CCDS14 MGGQVSASNSFSRLHCRNANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 EQPETVQNFVSVFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYF :. . .: . ... ... .. :: .::... : :: ::.::.::::. . ...:.: CCDS14 EESRLLQLLNKALPCITRPVVLKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKNLHF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 AHGLFS-AKVNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQMLKDIYGNKMC .: ... : :.. : ::. .: : .:::.: .: :... :: :: .:.:.:. .: CCDS14 VHMVYTTALVEDTLTEISEWLERHPREVVILACRNFEGLSEDLHEYLVACIKNIFGDMLC 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 PAIFAQEVSLKYLWEKDYQVLVFYHSPVALEVPF-LWPGQMMPAPWANTTDPEKLIQFLQ : .. .:. :: . ::.: :.. .:. :::: .: :.: . : ::..:. CCDS14 PR--GEVPTLRQLWSRGQQVIVSYEDESSLRRHHELWPG--VPYWWGNRVKTEALIRYLE 190 200 210 220 230 240 250 260 270 280 pF1KB7 ASITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWVRTQKPGESG- .. . :..:.. . :: . . :. . .: : .: :: . ::: : :: .. CCDS14 -TMKSCGRPGGLFVAGINLTENLQYVLAHPSESL-EKMTLPNLPRLSAWVREQCPGPGSR 240 250 260 270 280 290 290 300 310 320 pF1KB7 -INIVTADFVELGDFISTVIKLNYVFDEGEANT ::...::. :.: :: :: CCDS14 CTNIIAGDFIGADGFVSDVIALNQKLLWC 300 310 320 321 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 07:35:21 2016 done: Fri Nov 4 07:35:22 2016 Total Scan time: 2.500 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]