FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7417, 365 aa 1>>>pF1KB7417 365 - 365 aa - 365 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0645+/-0.000921; mu= 12.4427+/- 0.055 mean_var=78.8617+/-16.298, 0's: 0 Z-trim(106.6): 71 B-trim: 0 in 0/50 Lambda= 0.144425 statistics sampled from 9033 (9105) to 9033 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.28), width: 16 Scan time: 2.740 The best scores are: opt bits E(32554) CCDS44738.1 NXPE2 gene_id:120406|Hs108|chr11 ( 559) 2072 441.4 8.6e-124 CCDS41718.1 NXPE4 gene_id:54827|Hs108|chr11 ( 544) 1357 292.5 5.9e-79 CCDS8372.1 NXPE1 gene_id:120400|Hs108|chr11 ( 405) 819 180.3 2.5e-45 CCDS2945.1 NXPE3 gene_id:91775|Hs108|chr3 ( 559) 486 111.0 2.6e-24 >>CCDS44738.1 NXPE2 gene_id:120406|Hs108|chr11 (559 aa) initn: 2072 init1: 2072 opt: 2072 Z-score: 2335.9 bits: 441.4 E(32554): 8.6e-124 Smith-Waterman score: 2072; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308) 10 20 30 40 50 60 pF1KB7 MVEKILIHRILTLFPNAIARKLLLMLTFILIFWIIYLASKDHTKFSFNLENHIILNQGNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MVEKILIHRILTLFPNAIARKLLLMLTFILIFWIIYLASKDHTKFSFNLENHIILNQGNI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FKKYSHSETPLCPAVSPKETELRIKDIMEKLDQQIPPRPFTHVNTTTSATHSTATILNPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 FKKYSHSETPLCPAVSPKETELRIKDIMEKLDQQIPPRPFTHVNTTTSATHSTATILNPQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 DTYCRGDQLDILLEVRDHLGHRKQYGGDFLRARMYSTALMAGASGKVTDFNNGTYLVSFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DTYCRGDQLDILLEVRDHLGHRKQYGGDFLRARMYSTALMAGASGKVTDFNNGTYLVSFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LFWEGQVSLSLLLIHPSEGVSALWRARNQGCDRIIFTGLFANRSSNVFTECGLTLNTNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LFWEGQVSLSLLLIHPSEGVSALWRARNQGCDRIIFTGLFANRSSNVFTECGLTLNTNAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LCQYMDDRDQEAFYCVRPQHMPCEALTHMTTRTRNISYLSKEEWRLFHRSNIGVEMMKNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LCQYMDDRDQEAFYCVRPQHMPCEALTHMTTRTRNISYLSKEEWRLFHRSNIGVEMMKNF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 TPIEVIPCPALFYFIFRDSLTLSPRLECSGMISAHCNLCLPGSSDSPDSASHVAGITSVQ :::::::: CCDS44 TPIEVIPCNKSENIKKNCQIGMKTPFPSGYTLKKMWITAFCKQIKFNETKNINDCLERKL 310 320 330 340 350 360 >>CCDS41718.1 NXPE4 gene_id:54827|Hs108|chr11 (544 aa) initn: 1357 init1: 1357 opt: 1357 Z-score: 1531.0 bits: 292.5 E(32554): 5.9e-79 Smith-Waterman score: 1357; 71.8% identity (82.8% similar) in 291 aa overlap (18-308:6-296) 10 20 30 40 50 60 pF1KB7 MVEKILIHRILTLFPNAIARKLLLMLTFILIFWIIYLASKDHTKFSFNLENHIILNQGNI : : :: : ::: :::. . .. :: :. : :. : CCDS41 MKISMINYKSLLALLFILASWIIFTVFQNSTKVWSALNLSISLHYWNN 10 20 30 40 70 80 90 100 110 120 pF1KB7 FKKYSHSETPLCPAVSPKETELRIKDIMEKLDQQIPPRPFTHVNTTTSATHSTATILNPQ : .::: :::::::.:.:::::::::::::::::::::::::::::::. CCDS41 STKSLFPKTPLISLKPLTETELRIKEIIEKLDQQIPPRPFTHVNTTTSATHSTATILNPR 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 DTYCRGDQLDILLEVRDHLGHRKQYGGDFLRARMYSTALMAGASGKVTDFNNGTYLVSFT ::::::::: ::::::::::.::::::::::::: : ::::::::::::::::::::::: CCDS41 DTYCRGDQLHILLEVRDHLGRRKQYGGDFLRARMSSPALMAGASGKVTDFNNGTYLVSFT 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 LFWEGQVSLSLLLIHPSEGVSALWRARNQGCDRIIFTGLFANRSSNVFTECGLTLNTNAE :::::::::::::::::::::::: ::::: ::.:::: :.: .:.: .:::: :::::: CCDS41 LFWEGQVSLSLLLIHPSEGVSALWSARNQGYDRVIFTGQFVNGTSQVHSECGLILNTNAE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 LCQYMDDRDQEAFYCVRPQHMPCEALTHMTTRTRNISYLSKEEWRLFHRSNIGVEMMKNF ::::.:.::::.::::::::::: ::::: ......:::::.: ::.:::.:::.:..: CCDS41 LCQYLDNRDQEGFYCVRPQHMPCAALTHMYSKNKKVSYLSKQEKSLFERSNVGVEIMEKF 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 TPIEVIPCPALFYFIFRDSLTLSPRLECSGMISAHCNLCLPGSSDSPDSASHVAGITSVQ . : : : CCDS41 NTISVSKCNKETVAMKEKCKFGMTSTIPSGHVWRNTWNPVSCSLATVKMKECLRGKLIYL 290 300 310 320 330 340 >>CCDS8372.1 NXPE1 gene_id:120400|Hs108|chr11 (405 aa) initn: 794 init1: 794 opt: 819 Z-score: 927.2 bits: 180.3 E(32554): 2.5e-45 Smith-Waterman score: 819; 76.8% identity (89.7% similar) in 155 aa overlap (154-308:1-155) 130 140 150 160 170 180 pF1KB7 CRGDQLDILLEVRDHLGHRKQYGGDFLRARMYSTALMAGASGKVTDFNNGTYLVSFTLFW : : :: ::::::: ::::::::::::::: CCDS83 MSSPALTAGASGKVMDFNNGTYLVSFTLFW 10 20 30 190 200 210 220 230 240 pF1KB7 EGQVSLSLLLIHPSEGVSALWRARNQGCDRIIFTGLFANRSSNVFTECGLTLNTNAELCQ ::::::::::::::::.:::::::::: :.::: : :.: .:.::::::::::.:::::. CCDS83 EGQVSLSLLLIHPSEGASALWRARNQGYDKIIFKGKFVNGTSHVFTECGLTLNSNAELCE 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB7 YMDDRDQEAFYCVRPQHMPCEALTHMTTRTRNISYLSKEEWRLFHRSNIGVEMMKNFTPI :.::::::::::..::::::::::.::::.:..:::. .: :::::..::::::. : CCDS83 YLDDRDQEAFYCMKPQHMPCEALTYMTTRNREVSYLTDKENSLFHRSKVGVEMMKDRKHI 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB7 EVIPCPALFYFIFRDSLTLSPRLECSGMISAHCNLCLPGSSDSPDSASHVAGITSVQRHT .: : CCDS83 DVTNCNKREKIEETCQVGMKPPVPGGYTLQGKWITTFCNQVQLDTIKINGCLKGKLIYLL 160 170 180 190 200 210 >>CCDS2945.1 NXPE3 gene_id:91775|Hs108|chr3 (559 aa) initn: 455 init1: 430 opt: 486 Z-score: 550.0 bits: 111.0 E(32554): 2.6e-24 Smith-Waterman score: 486; 31.1% identity (62.2% similar) in 299 aa overlap (22-307:15-303) 10 20 30 40 50 60 pF1KB7 MVEKILIHRILTLFPNAIARKLLLMLTFILIFWIIYLASKDHTKFSFNLENHIILNQGNI : .... .:.. . . :: : .. : ..:.. CCDS29 MWTNFFKLRLFCCLLAVLMVVVLVINVTQVEYLDHETVSATF----IDSSGQF 10 20 30 40 70 80 90 100 110 pF1KB7 FKKYSH--SETPLC----PAVSPKETELRIKDIMEKLDQQIP---PRPFTHVNTTTSATH .. :..: : ..: .: ... ... : .:.: : ::.. .:. . CCDS29 VSSQVTGISRNPYCGYDQQTLSSQE-RMEEDSLLAALHRQVPDVGPVPFVK---STDPSS 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 STATILNPQDTYCRGDQLDILLEVRDHLGHRKQYGGDFLRARMYSTALMAGASGKVTDFN : .::: . :.::..:..:.: . :.::::.:.::..: :.::: :.:.:.. CCDS29 SYFVILNSAAFFKVGSQLEVLVHVQDFQRKPKKYGGDYLQARIHSLKLQAGAVGRVVDYQ 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 NGTYLVSFTLFWEGQVSLSLLLIHPSEGVSALWRARNQGCDRIIFTGLFANRSSNVFTEC :: : : :::.: :.:..:. :.:::::. .: : ... ::. : .:: . . ::: CCDS29 NGFYKVFFTLLWPGKVKVSVSLVHPSEGIRVLQRLQEDKPDRVYFKSLFRSGRISETTEC 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 GLTLNTNAELCQYMDDRDQEAFYCVRPQHMPCEA-LTHMTTRTRNISYLSKEEWRLFHRS .. : : ::.. : : ..: .:...:: . .::. . .. : : .: CCDS29 NVCLPGNLPLCNFTDLYTGEPWFCFKPKKLPCSSRITHF--KGGYLKGLLTAAESAFFQS 230 240 250 260 270 280 300 310 320 330 340 pF1KB7 NIGVEMMKNFT-P--IEVIPCPALFYFIFRDSLTLSPRLECSGMISAHCNLCLPGSSDSP .....: : . : . ::: CCDS29 GVNIKMPVNSSGPDWVTVIPRRIKETNSLELSQGSGTFPSGYYYKDQWRPRKFKMRQFND 290 300 310 320 330 340 365 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 07:36:34 2016 done: Fri Nov 4 07:36:34 2016 Total Scan time: 2.740 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]