FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7420, 269 aa 1>>>pF1KB7420 269 - 269 aa - 269 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0279+/-0.000923; mu= 11.2125+/- 0.055 mean_var=86.8431+/-17.365, 0's: 0 Z-trim(107.4): 59 B-trim: 65 in 1/50 Lambda= 0.137628 statistics sampled from 9527 (9578) to 9527 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.294), width: 16 Scan time: 2.310 The best scores are: opt bits E(32554) CCDS41883.1 SIAH3 gene_id:283514|Hs108|chr13 ( 269) 1908 388.7 2.4e-108 CCDS3152.1 SIAH2 gene_id:6478|Hs108|chr3 ( 324) 660 140.9 1.1e-33 CCDS10735.1 SIAH1 gene_id:6477|Hs108|chr16 ( 282) 636 136.1 2.6e-32 CCDS32444.1 SIAH1 gene_id:6477|Hs108|chr16 ( 313) 636 136.1 2.9e-32 >>CCDS41883.1 SIAH3 gene_id:283514|Hs108|chr13 (269 aa) initn: 1908 init1: 1908 opt: 1908 Z-score: 2058.8 bits: 388.7 E(32554): 2.4e-108 Smith-Waterman score: 1908; 100.0% identity (100.0% similar) in 269 aa overlap (1-269:1-269) 10 20 30 40 50 60 pF1KB7 MLFFTQCFGAVLDLIHLRFQHYKAKRVFSAAGQLVCVVNPTHNLKYVSSRRAVTQSAPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MLFFTQCFGAVLDLIHLRFQHYKAKRVFSAAGQLVCVVNPTHNLKYVSSRRAVTQSAPEQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHANPVTPCLCMCPLFSCQWEGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHANPVTPCLCMCPLFSCQWEGRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EVVVPHLRQIHRVDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQERHEGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EVVVPHLRQIHRVDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQERHEGH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLVLNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLVLNTS 190 200 210 220 230 240 250 260 pF1KB7 LAQLFSDNGSLAIGIAITATEVLPSEAEM ::::::::::::::::::::::::::::: CCDS41 LAQLFSDNGSLAIGIAITATEVLPSEAEM 250 260 >>CCDS3152.1 SIAH2 gene_id:6478|Hs108|chr3 (324 aa) initn: 634 init1: 536 opt: 660 Z-score: 718.3 bits: 140.9 E(32554): 1.1e-33 Smith-Waterman score: 660; 54.1% identity (79.7% similar) in 172 aa overlap (90-258:149-320) 60 70 80 90 100 110 pF1KB7 QGSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHAN--PVTPCLCMCPLFSCQWE ::: : : . : : :: ::.:. CCDS31 TPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQ 120 130 140 150 160 170 120 130 140 150 160 170 pF1KB7 GRLEVVVPHLRQIHR-VDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQER : ::.:. :: . :. . ::: .:::::::..::. .::..:.::.::::.:::.:::. CCDS31 GSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEK 180 190 200 210 220 230 180 190 200 210 220 230 pF1KB7 HEGHPQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLV .::: :::: ..:::: ::. :.:::::: :.::: :::::::. . : ..: ..:::: CCDS31 YEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLV 240 250 260 270 280 290 240 250 260 pF1KB7 LNTSLAQLFSDNGSLAIGIAITATEVLPSEAEM ..:..:.::.:::.:.:...:. CCDS31 FDTAIAHLFADNGNLGINVTISTCCP 300 310 320 >>CCDS10735.1 SIAH1 gene_id:6477|Hs108|chr16 (282 aa) initn: 623 init1: 520 opt: 636 Z-score: 693.5 bits: 136.1 E(32554): 2.6e-32 Smith-Waterman score: 636; 52.3% identity (79.7% similar) in 172 aa overlap (90-258:109-280) 60 70 80 90 100 110 pF1KB7 QGSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHAN--PVTPCLCMCPLFSCQWE : : : . : . : : :: ::.:. CCDS10 LGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQ 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB7 GRLEVVVPHLRQIHR-VDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQER : :..:.::: . :. . ::: .:::::::..::. .::..:.::.: ::.:::.:::. CCDS10 GSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEK 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB7 HEGHPQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLV ..:: :::: ..:::: ::. :.:::::: ..::: :::::::. : . ..: ..:::: CCDS10 YDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLV 200 210 220 230 240 250 240 250 260 pF1KB7 LNTSLAQLFSDNGSLAIGIAITATEVLPSEAEM ..::.::::..::.:.:...:. CCDS10 FDTSIAQLFAENGNLGINVTISMC 260 270 280 >>CCDS32444.1 SIAH1 gene_id:6477|Hs108|chr16 (313 aa) initn: 623 init1: 520 opt: 636 Z-score: 692.8 bits: 136.1 E(32554): 2.9e-32 Smith-Waterman score: 636; 52.3% identity (79.7% similar) in 172 aa overlap (90-258:140-311) 60 70 80 90 100 110 pF1KB7 QGSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHAN--PVTPCLCMCPLFSCQWE : : : . : . : : :: ::.:. CCDS32 LGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQ 110 120 130 140 150 160 120 130 140 150 160 170 pF1KB7 GRLEVVVPHLRQIHR-VDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQER : :..:.::: . :. . ::: .:::::::..::. .::..:.::.: ::.:::.:::. CCDS32 GSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEK 170 180 190 200 210 220 180 190 200 210 220 230 pF1KB7 HEGHPQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLV ..:: :::: ..:::: ::. :.:::::: ..::: :::::::. : . ..: ..:::: CCDS32 YDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLV 230 240 250 260 270 280 240 250 260 pF1KB7 LNTSLAQLFSDNGSLAIGIAITATEVLPSEAEM ..::.::::..::.:.:...:. CCDS32 FDTSIAQLFAENGNLGINVTISMC 290 300 310 269 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 07:38:10 2016 done: Fri Nov 4 07:38:11 2016 Total Scan time: 2.310 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]