Result of FASTA (omim) for
pF1KB7420
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7420, 269 aa
1>>>pF1KB7420 269 - 269 aa - 269 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3670+/-0.000399; mu= 9.2696+/- 0.025
mean_var=92.7440+/-19.115, 0's: 0 Z-trim(114.2): 102 B-trim: 178 in 1/49
Lambda= 0.133178
statistics sampled from 23888 (23995) to 23888 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.281), width: 16
Scan time: 5.800
The best scores are: opt bits E(85289)
NP_942146 (OMIM: 615609) seven in absentia homolog ( 269) 1908 376.8 2.3e-104
NP_005058 (OMIM: 602213) E3 ubiquitin-protein liga ( 324) 660 137.0 4.2e-32
XP_011521581 (OMIM: 602212) PREDICTED: E3 ubiquiti ( 282) 636 132.4 9.1e-31
NP_003022 (OMIM: 602212) E3 ubiquitin-protein liga ( 282) 636 132.4 9.1e-31
XP_006721309 (OMIM: 602212) PREDICTED: E3 ubiquiti ( 282) 636 132.4 9.1e-31
NP_001006611 (OMIM: 602212) E3 ubiquitin-protein l ( 313) 636 132.4 9.9e-31
>>NP_942146 (OMIM: 615609) seven in absentia homolog 3 [ (269 aa)
initn: 1908 init1: 1908 opt: 1908 Z-score: 1994.5 bits: 376.8 E(85289): 2.3e-104
Smith-Waterman score: 1908; 100.0% identity (100.0% similar) in 269 aa overlap (1-269:1-269)
10 20 30 40 50 60
pF1KB7 MLFFTQCFGAVLDLIHLRFQHYKAKRVFSAAGQLVCVVNPTHNLKYVSSRRAVTQSAPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MLFFTQCFGAVLDLIHLRFQHYKAKRVFSAAGQLVCVVNPTHNLKYVSSRRAVTQSAPEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHANPVTPCLCMCPLFSCQWEGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 GSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHANPVTPCLCMCPLFSCQWEGRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EVVVPHLRQIHRVDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQERHEGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EVVVPHLRQIHRVDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQERHEGH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 PQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLVLNTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 PQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLVLNTS
190 200 210 220 230 240
250 260
pF1KB7 LAQLFSDNGSLAIGIAITATEVLPSEAEM
:::::::::::::::::::::::::::::
NP_942 LAQLFSDNGSLAIGIAITATEVLPSEAEM
250 260
>>NP_005058 (OMIM: 602213) E3 ubiquitin-protein ligase S (324 aa)
initn: 634 init1: 536 opt: 660 Z-score: 697.4 bits: 137.0 E(85289): 4.2e-32
Smith-Waterman score: 660; 54.1% identity (79.7% similar) in 172 aa overlap (90-258:149-320)
60 70 80 90 100 110
pF1KB7 QGSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHAN--PVTPCLCMCPLFSCQWE
::: : : . : : :: ::.:.
NP_005 TPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQ
120 130 140 150 160 170
120 130 140 150 160 170
pF1KB7 GRLEVVVPHLRQIHR-VDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQER
: ::.:. :: . :. . ::: .:::::::..::. .::..:.::.::::.:::.:::.
NP_005 GSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEK
180 190 200 210 220 230
180 190 200 210 220 230
pF1KB7 HEGHPQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLV
.::: :::: ..:::: ::. :.:::::: :.::: :::::::. . : ..: ..::::
NP_005 YEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLV
240 250 260 270 280 290
240 250 260
pF1KB7 LNTSLAQLFSDNGSLAIGIAITATEVLPSEAEM
..:..:.::.:::.:.:...:.
NP_005 FDTAIAHLFADNGNLGINVTISTCCP
300 310 320
>>XP_011521581 (OMIM: 602212) PREDICTED: E3 ubiquitin-pr (282 aa)
initn: 623 init1: 520 opt: 636 Z-score: 673.4 bits: 132.4 E(85289): 9.1e-31
Smith-Waterman score: 636; 52.3% identity (79.7% similar) in 172 aa overlap (90-258:109-280)
60 70 80 90 100 110
pF1KB7 QGSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHAN--PVTPCLCMCPLFSCQWE
: : : . : . : : :: ::.:.
XP_011 LGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQ
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB7 GRLEVVVPHLRQIHR-VDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQER
: :..:.::: . :. . ::: .:::::::..::. .::..:.::.: ::.:::.:::.
XP_011 GSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEK
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB7 HEGHPQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLV
..:: :::: ..:::: ::. :.:::::: ..::: :::::::. : . ..: ..::::
XP_011 YDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLV
200 210 220 230 240 250
240 250 260
pF1KB7 LNTSLAQLFSDNGSLAIGIAITATEVLPSEAEM
..::.::::..::.:.:...:.
XP_011 FDTSIAQLFAENGNLGINVTISMC
260 270 280
>>NP_003022 (OMIM: 602212) E3 ubiquitin-protein ligase S (282 aa)
initn: 623 init1: 520 opt: 636 Z-score: 673.4 bits: 132.4 E(85289): 9.1e-31
Smith-Waterman score: 636; 52.3% identity (79.7% similar) in 172 aa overlap (90-258:109-280)
60 70 80 90 100 110
pF1KB7 QGSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHAN--PVTPCLCMCPLFSCQWE
: : : . : . : : :: ::.:.
NP_003 LGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQ
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB7 GRLEVVVPHLRQIHR-VDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQER
: :..:.::: . :. . ::: .:::::::..::. .::..:.::.: ::.:::.:::.
NP_003 GSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEK
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB7 HEGHPQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLV
..:: :::: ..:::: ::. :.:::::: ..::: :::::::. : . ..: ..::::
NP_003 YDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLV
200 210 220 230 240 250
240 250 260
pF1KB7 LNTSLAQLFSDNGSLAIGIAITATEVLPSEAEM
..::.::::..::.:.:...:.
NP_003 FDTSIAQLFAENGNLGINVTISMC
260 270 280
>>XP_006721309 (OMIM: 602212) PREDICTED: E3 ubiquitin-pr (282 aa)
initn: 623 init1: 520 opt: 636 Z-score: 673.4 bits: 132.4 E(85289): 9.1e-31
Smith-Waterman score: 636; 52.3% identity (79.7% similar) in 172 aa overlap (90-258:109-280)
60 70 80 90 100 110
pF1KB7 QGSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHAN--PVTPCLCMCPLFSCQWE
: : : . : . : : :: ::.:.
XP_006 LGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQ
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB7 GRLEVVVPHLRQIHR-VDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQER
: :..:.::: . :. . ::: .:::::::..::. .::..:.::.: ::.:::.:::.
XP_006 GSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEK
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB7 HEGHPQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLV
..:: :::: ..:::: ::. :.:::::: ..::: :::::::. : . ..: ..::::
XP_006 YDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLV
200 210 220 230 240 250
240 250 260
pF1KB7 LNTSLAQLFSDNGSLAIGIAITATEVLPSEAEM
..::.::::..::.:.:...:.
XP_006 FDTSIAQLFAENGNLGINVTISMC
260 270 280
>>NP_001006611 (OMIM: 602212) E3 ubiquitin-protein ligas (313 aa)
initn: 623 init1: 520 opt: 636 Z-score: 672.7 bits: 132.4 E(85289): 9.9e-31
Smith-Waterman score: 636; 52.3% identity (79.7% similar) in 172 aa overlap (90-258:140-311)
60 70 80 90 100 110
pF1KB7 QGSFHPHHLSHHHCHHRHHHHLRHHAHPHHLHHQEAGLHAN--PVTPCLCMCPLFSCQWE
: : : . : . : : :: ::.:.
NP_001 LGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQ
110 120 130 140 150 160
120 130 140 150 160 170
pF1KB7 GRLEVVVPHLRQIHR-VDILQGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQER
: :..:.::: . :. . ::: .:::::::..::. .::..:.::.: ::.:::.:::.
NP_001 GSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEK
170 180 190 200 210 220
180 190 200 210 220 230
pF1KB7 HEGHPQFFATMMLIGTPTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLV
..:: :::: ..:::: ::. :.:::::: ..::: :::::::. : . ..: ..::::
NP_001 YDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLV
230 240 250 260 270 280
240 250 260
pF1KB7 LNTSLAQLFSDNGSLAIGIAITATEVLPSEAEM
..::.::::..::.:.:...:.
NP_001 FDTSIAQLFAENGNLGINVTISMC
290 300 310
269 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 07:38:11 2016 done: Fri Nov 4 07:38:12 2016
Total Scan time: 5.800 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]