Result of FASTA (omim) for
pF1KB7426
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7426, 412 aa
1>>>pF1KB7426 412 - 412 aa - 412 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8152+/-0.000304; mu= 12.7353+/- 0.019
mean_var=145.2494+/-31.198, 0's: 0 Z-trim(121.8): 539 B-trim: 3762 in 2/54
Lambda= 0.106418
statistics sampled from 38154 (38854) to 38154 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.456), width: 16
Scan time: 9.900
The best scores are: opt bits E(85289)
NP_001498 (OMIM: 602885) motilin receptor [Homo sa ( 412) 2788 439.1 9.4e-123
NP_004113 (OMIM: 601898) growth hormone secretagog ( 289) 645 110.0 8e-24
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366) 645 110.1 9.5e-24
NP_036476 (OMIM: 605538) neurotensin receptor type ( 410) 512 89.7 1.4e-17
XP_011535972 (OMIM: 605108) PREDICTED: neuromedin- ( 321) 426 76.4 1.1e-13
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 426 76.5 1.4e-13
XP_011527129 (OMIM: 162651) PREDICTED: neurotensin ( 336) 419 75.3 2.5e-13
NP_002522 (OMIM: 162651) neurotensin receptor type ( 418) 419 75.4 2.9e-13
XP_011508791 (OMIM: 604153) PREDICTED: neuromedin- ( 313) 407 73.5 8.5e-13
XP_006712259 (OMIM: 604153) PREDICTED: neuromedin- ( 333) 407 73.5 8.8e-13
XP_006712258 (OMIM: 604153) PREDICTED: neuromedin- ( 370) 407 73.5 9.5e-13
XP_011508790 (OMIM: 604153) PREDICTED: neuromedin- ( 376) 407 73.5 9.7e-13
XP_011508789 (OMIM: 604153) PREDICTED: neuromedin- ( 403) 407 73.6 1e-12
NP_006047 (OMIM: 604153) neuromedin-U receptor 1 [ ( 426) 407 73.6 1.1e-12
XP_005246213 (OMIM: 605538) PREDICTED: neurotensin ( 250) 363 66.6 7.8e-11
XP_006711940 (OMIM: 605538) PREDICTED: neurotensin ( 319) 362 66.6 1e-10
XP_006711939 (OMIM: 605538) PREDICTED: neurotensin ( 322) 362 66.6 1e-10
XP_016859227 (OMIM: 605538) PREDICTED: neurotensin ( 339) 362 66.6 1.1e-10
NP_001499 (OMIM: 602886) G-protein coupled recepto ( 453) 314 59.3 2.2e-08
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 313 59.2 2.3e-08
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 313 59.2 2.3e-08
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 313 59.2 2.3e-08
XP_011509323 (OMIM: 602886) PREDICTED: G-protein c ( 293) 306 57.9 3.8e-08
NP_000855 (OMIM: 182133) 5-hydroxytryptamine recep ( 377) 306 58.0 4.5e-08
NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 300 57.1 8.3e-08
NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 300 57.1 8.3e-08
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 296 56.5 1.3e-07
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 294 56.2 1.6e-07
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 294 56.2 1.6e-07
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 294 56.2 1.6e-07
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 294 56.2 1.6e-07
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 294 56.2 1.6e-07
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 294 56.2 1.6e-07
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 294 56.2 1.6e-07
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 294 56.2 1.7e-07
NP_005276 (OMIM: 600730) neuropeptides B/W recepto ( 328) 291 55.7 2e-07
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 286 55.0 3.8e-07
NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 286 55.0 3.8e-07
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 286 55.0 4e-07
NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 285 54.8 4e-07
NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 285 54.8 4e-07
XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 285 54.8 4e-07
XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 285 54.8 4e-07
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 287 55.2 4e-07
NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 285 54.8 4.2e-07
NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 285 54.8 4.2e-07
XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 285 54.8 4.5e-07
XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 285 54.8 4.5e-07
NP_000701 (OMIM: 600337) B1 bradykinin receptor [H ( 353) 283 54.5 5e-07
NP_001243689 (OMIM: 312861) 5-hydroxytryptamine re ( 458) 284 54.7 5.4e-07
>>NP_001498 (OMIM: 602885) motilin receptor [Homo sapien (412 aa)
initn: 2788 init1: 2788 opt: 2788 Z-score: 2324.8 bits: 439.1 E(85289): 9.4e-123
Smith-Waterman score: 2788; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KB7 MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 CTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 QDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 QLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISK
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 KYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG
370 380 390 400 410
>>NP_004113 (OMIM: 601898) growth hormone secretagogue r (289 aa)
initn: 854 init1: 637 opt: 645 Z-score: 548.7 bits: 110.0 E(85289): 8e-24
Smith-Waterman score: 794; 45.1% identity (67.0% similar) in 306 aa overlap (5-300:2-265)
10 20 30 40 50
pF1KB7 MGSPWNGSDGPEGA-----REPPWPALPPCD---ERRCSPFPLGALVPVTAVCLCLFVVG
::.. . : . . : : : : .. . :: :. :::.:. :::::
NP_004 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVG
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 VSGNVVTVMLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCR
..::..:.....:.:..::::::::.::: :::::.: .:.:: :::. ::: :: :::.
NP_004 IAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 LSLYVGEGCTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGP
: .:.:.:::::.: .::::::::.::: ::::.:.::. ::. .: :.::::. ::::
NP_004 LFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 FLFLVGVEQDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFS
.. :::::.. ::: .: : .
NP_004 IFVLVGVEHE---------NGT-----DP-------WDTN--------------------
180 190
240 250 260 270 280 290
pF1KB7 RECRPSP--AQLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRE
::::. .. : : ::.::.. .:::: .::..::.::::.:: :: .:: :.
NP_004 -ECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRD
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB7 RGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASI
..:.:::..:
NP_004 QNHKQTVKMLGGSQRALRLSLAGPILSLCLLPSL
260 270 280
>>NP_940799 (OMIM: 601898) growth hormone secretagogue r (366 aa)
initn: 1137 init1: 637 opt: 645 Z-score: 547.4 bits: 110.1 E(85289): 9.5e-24
Smith-Waterman score: 1073; 45.0% identity (68.8% similar) in 407 aa overlap (5-398:2-366)
10 20 30 40 50
pF1KB7 MGSPWNGSDGPEGA-----REPPWPALPPCD---ERRCSPFPLGALVPVTAVCLCLFVVG
::.. . : . . : : : : .. . :: :. :::.:. :::::
NP_940 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVG
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 VSGNVVTVMLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCR
..::..:.....:.:..::::::::.::: :::::.: .:.:: :::. ::: :: :::.
NP_940 IAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 LSLYVGEGCTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGP
: .:.:.:::::.: .::::::::.::: ::::.:.::. ::. .: :.::::. ::::
NP_940 LFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 FLFLVGVEQDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFS
.. :::::.. ::: .: : .
NP_940 IFVLVGVEHE---------NGT-----DP-------WDTN--------------------
180 190
240 250 260 270 280 290
pF1KB7 RECRPSP--AQLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRE
::::. .. : : ::.::.. .:::: .::..::.::::.:: :: .:: :.
NP_940 -ECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRD
200 210 220 230 240 250
300 310 320 330 340
pF1KB7 RGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINTEDS---RMMYFSQYFNIVALQLFYLS
..:.:::..: :::.:::.::::::::: .. .. . .. .::: :.:.. :::::
NP_940 QNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLS
260 270 280 290 300 310
350 360 370 380 390 400
pF1KB7 ASINPILYNLISKKYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSAN
:.:::::::..:::::.:.:.:: . : . .: .... ... .:
NP_940 AAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT
320 330 340 350 360
410
pF1KB7 VKTMG
>>NP_036476 (OMIM: 605538) neurotensin receptor type 2 [ (410 aa)
initn: 477 init1: 260 opt: 512 Z-score: 436.4 bits: 89.7 E(85289): 1.4e-17
Smith-Waterman score: 516; 31.8% identity (57.6% similar) in 387 aa overlap (17-381:8-380)
10 20 30 40 50
pF1KB7 MGSPWNGSDGPEGAREPPWPALPP---CDERRCSPFPLGALVPVTAVCLCLFVVGVSGNV
:: :. : : : : : : ::. ....:..::.
NP_036 METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNA
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 VTVMLIGRYRDMRT-TTNLYLGSMAVSDLLILL-GLPFDLYRL-WRSRPWVFGPLLCRLS
..: .. . : :. .. :.:.. ::.:: :.: .:: . : ::::: : ::
NP_036 LSVHVVLKARAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 LYVGEGCTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFL
.: : :.:::.: ...::.:: ::.:.::::: :.: ::.: :.:. ::..: : :.
NP_036 YFVHELCAYATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMA
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 FLVGVEQDPGISVVPGLNGTARIASSPLASSPPLWL--------SRAPPPSPPS---GPE
..: : . .. : : . . :.: : . : . : . . :
NP_036 VIMG--QKHELETADGEPEPASRVCTVLVSRTALQVFIQVNVLVSFVLPLALTAFLNGVT
180 190 200 210 220
230 240 250 260 270 280
pF1KB7 TAEAAALFSRECRPSPAQLGALR-VMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLR
... :: :. :: . :. : . . .: :. . . :. .. .:
NP_036 VSHLLALCSQV--PSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQVSLVRHKDVR
230 240 250 260 270 280
290 300 310 320 330
pF1KB7 GPAASGRERGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINTEDSR----MMYFSQYFNI
: :. ...:.:: ..:. ..:::::.:. :..: . :. .. : .:: .
NP_036 ------RIRSLQRSVQVLRAIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYM
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB7 VALQLFYLSASINPILYNLISKKYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDT
:. :::.:....:.::: .:...: ::.: : : :
NP_036 VTNTLFYVSSAVTPLLYNAVSSSFR----KLFLEAVSSLCGEHHPMKRLPPKPQSPTLMD
350 360 370 380 390
400 410
pF1KB7 VGYTETSANVKTMG
NP_036 TASGFGDPPETRT
400 410
>>XP_011535972 (OMIM: 605108) PREDICTED: neuromedin-U re (321 aa)
initn: 344 init1: 266 opt: 426 Z-score: 366.4 bits: 76.4 E(85289): 1.1e-13
Smith-Waterman score: 501; 31.1% identity (60.6% similar) in 315 aa overlap (30-339:37-308)
10 20 30 40 50
pF1KB7 MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVT
:.: ..::..: . .::::: :::..
XP_011 LQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGVIGNVLV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 VMLIGRYRDMRTTTNLYLGSMAVSDLLILL-GLPFDLYRLWRSRPWVFGPLLCRLSLYVG
..: ... :.: :: :: :.::::::.:: :.:...:..::. :..:::. : .. .
XP_011 CLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 EGCTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVG
: .:..: .:..:::::.:: .:.::.. ::::. .....:. ..: . : . :
XP_011 ETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 VEQD--PGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECR
.. :. :.::: :. . :.:.
XP_011 IKFHYFPNGSLVPG--------SATCTVIKPMWI--------------------------
190 200 210
240 250 260 270 280 290
pF1KB7 PSPAQLGALRVMLWVTTAYFFL-PFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQ
.. ::. :.: :. .:.:: :.. .: ... . .. .: :.
XP_011 --------YNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEGNANIQRPCRK
220 230 240 250 260
300 310 320 330 340 350
pF1KB7 TV-RVLLVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPIL
.: ..:.:.::.: ::: :::. :... .:. .. ::.:
XP_011 SVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSES-LAAVFNLVHVVSGKTLAGFGA
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB7 YNLISKKYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG
>>NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [Homo (415 aa)
initn: 435 init1: 266 opt: 426 Z-score: 364.9 bits: 76.5 E(85289): 1.4e-13
Smith-Waterman score: 590; 31.1% identity (62.8% similar) in 363 aa overlap (30-385:37-354)
10 20 30 40 50
pF1KB7 MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVT
:.: ..::..: . .::::: :::..
NP_064 LQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGVIGNVLV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 VMLIGRYRDMRTTTNLYLGSMAVSDLLILL-GLPFDLYRLWRSRPWVFGPLLCRLSLYVG
..: ... :.: :: :: :.::::::.:: :.:...:..::. :..:::. : .. .
NP_064 CLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 EGCTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVG
: .:..: .:..:::::.:: .:.::.. ::::. .....:. ..: . : . :
NP_064 ETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 VEQD--PGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECR
.. :. :.::: ..: . . :.:.
NP_064 IKFHYFPNGSLVPG-SATCTVIK-------PMWI--------------------------
190 200 210
240 250 260 270 280 290
pF1KB7 PSPAQLGALRVMLWVTTAYFFL-PFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQ
.. ::. :.: :. .:.:: :.. .: ... . .. .: :.
NP_064 --------YNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEGNANIQRPCRK
220 230 240 250 260
300 310 320 330 340 350
pF1KB7 TV-RVLLVVVLAFIICWLPFHVGRIIYINTED--SRMMYFSQYFNIVALQLFYLSASINP
.: ..:.:.::.: ::: :::. :... .:. . . ..:. .::::...::
NP_064 SVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSESLAAVFNLVHVVSGVFFYLSSAVNP
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB7 ILYNLISKKYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG
:.:::.:....:: :. ... : . .: ..:
NP_064 IIYNLLSRRFQAA-FQNVIS--SFHKQWHSQHDPQLPPAQRNIFLTECHFVELTEDIGPQ
330 340 350 360 370 380
NP_064 FPCQSSMHNSHLPAALSSEQMSRTNYQSFHFNKT
390 400 410
>>XP_011527129 (OMIM: 162651) PREDICTED: neurotensin rec (336 aa)
initn: 467 init1: 257 opt: 419 Z-score: 360.3 bits: 75.3 E(85289): 2.5e-13
Smith-Waterman score: 481; 33.5% identity (61.6% similar) in 310 aa overlap (39-326:64-331)
10 20 30 40 50 60
pF1KB7 DGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTVMLIGRYRD
: :::: : :::::. ::.::.. ..: ..
XP_011 GFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKS
40 50 60 70 80 90
70 80 90 100 110 120
pF1KB7 MRT---TTNLYLGSMAVSDLL-ILLGLPFDLYR-LWRSRPWVFGPLLCRLSLYVGEGCTY
... :.. .:::.:.:::: .::..: .:: .: .::.:: :: .. ..:::
XP_011 LQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTY
100 110 120 130 140 150
130 140 150 160 170 180
pF1KB7 ATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVEQDP
:: :....::::::::::.:..:..:..: :.. .:...: .. : : :.:: .: ::.
XP_011 ATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMG-EQN-
160 170 180 190 200 210
190 200 210 220 230 240
pF1KB7 GISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPAQLG
: :.. .:..: : :. . .
XP_011 ------------RSADGQ------------------------HAGGLV---CTPT-IHTA
220 230
250 260 270 280
pF1KB7 ALRVMLWVTTAY-FFLPFLCLSILYGLIGRELWSSRRPL--RGPAAS-------------
...:.. :.: . :..:.. .:.: .:. .: : .: . .
XP_011 TVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIE
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 -GRERGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYL
:: .. :. :::: .::.::..::::.:: :... :
XP_011 PGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTP
300 310 320 330
350 360 370 380 390 400
pF1KB7 SASINPILYNLISKKYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSA
>>NP_002522 (OMIM: 162651) neurotensin receptor type 1 [ (418 aa)
initn: 576 init1: 257 opt: 419 Z-score: 359.1 bits: 75.4 E(85289): 2.9e-13
Smith-Waterman score: 598; 34.7% identity (62.6% similar) in 380 aa overlap (39-386:64-401)
10 20 30 40 50 60
pF1KB7 DGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTVMLIGRYRD
: :::: : :::::. ::.::.. ..: ..
NP_002 GFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKS
40 50 60 70 80 90
70 80 90 100 110 120
pF1KB7 MRT---TTNLYLGSMAVSDLL-ILLGLPFDLYR-LWRSRPWVFGPLLCRLSLYVGEGCTY
... :.. .:::.:.:::: .::..: .:: .: .::.:: :: .. ..:::
NP_002 LQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTY
100 110 120 130 140 150
130 140 150 160 170 180
pF1KB7 ATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVEQDP
:: :....::::::::::.:..:..:..: :.. .:...: .. : : :.:: .: ::.
NP_002 ATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMG-EQN-
160 170 180 190 200 210
190 200 210 220 230 240
pF1KB7 GISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPAQLG
: :.. .:..: : :. . .
NP_002 ------------RSADGQ------------------------HAGGLV---CTPT-IHTA
220 230
250 260 270 280
pF1KB7 ALRVMLWVTTAY-FFLPFLCLSILYGLIGRELWSSRRPL--RGPAAS-------------
...:.. :.: . :..:.. .:.: .:. .: : .: . .
NP_002 TVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIE
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 -GRERGHRQTVRVLLVVVLAFIICWLPFHVGRII--YINTED-SRMMY-FSQYFNIVALQ
:: .. :. :::: .::.::..::::.:: :.. ::. :. . ..: : .:: .:.
NP_002 PGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNA
300 310 320 330 340 350
350 360 370 380 390
pF1KB7 LFYLSASINPILYNLISKKYRAAAFKLL-----LARKSRPR-GFHRSRDTAGEVAGDTGG
:::.:..::::::::.: ..: . : . :. : : .: :. :.
NP_002 LFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSN
360 370 380 390 400 410
400 410
pF1KB7 DTVGYTETSANVKTMG
NP_002 ATRETLY
>>XP_011508791 (OMIM: 604153) PREDICTED: neuromedin-U re (313 aa)
initn: 358 init1: 263 opt: 407 Z-score: 350.8 bits: 73.5 E(85289): 8.5e-13
Smith-Waterman score: 414; 35.2% identity (57.7% similar) in 281 aa overlap (38-300:60-299)
10 20 30 40 50 60
pF1KB7 SDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTVMLIGRYR
..:. :. : .::::. :: .: ..: :..
XP_011 AARGHFDPEDLNLTDEALRLKYLGPQQTELFMPICATYLLIFVVGAVGNGLTCLVILRHK
30 40 50 60 70 80
70 80 90 100 110 120
pF1KB7 DMRTTTNLYLGSMAVSDLLILL-GLPFDLYRLWRSRPWVFGPLLCRLSLYVGEGCTYATL
::: :: :: :.::::::.:: :::..::..:.. :...: : . . : :..
XP_011 AMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHNYPFLLGVGGCYFRTLLFEMVCLASV
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB7 LHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVEQDPGIS
:..::::::::.:. .::.:: .::: .:: .....:..:.: . : : :..: .
XP_011 LNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQ---LH
150 160 170 180 190 200
190 200 210 220 230 240
pF1KB7 VVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPAQLGALR
: : :: :. .. :: ::
XP_011 V------------------------------PCRGPVPDSAVCML---VRPR-----ALY
210 220
250 260 270 280
pF1KB7 VMLWVTTA--YFFLPFLCLSILYGLIGRELWSSRRPL------RGPAAS---------GR
:. ::: .: ::. .:.:: ::: .: : : :: ::. .
XP_011 NMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQH
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB7 ERGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSAS
.::.::....:
XP_011 DRGRRQVTKMLSACEAWPPARHLLS
290 300 310
>>XP_006712259 (OMIM: 604153) PREDICTED: neuromedin-U re (333 aa)
initn: 510 init1: 237 opt: 407 Z-score: 350.4 bits: 73.5 E(85289): 8.8e-13
Smith-Waterman score: 417; 35.3% identity (57.6% similar) in 283 aa overlap (38-302:60-301)
10 20 30 40 50 60
pF1KB7 SDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTVMLIGRYR
..:. :. : .::::. :: .: ..: :..
XP_006 AARGHFDPEDLNLTDEALRLKYLGPQQTELFMPICATYLLIFVVGAVGNGLTCLVILRHK
30 40 50 60 70 80
70 80 90 100 110 120
pF1KB7 DMRTTTNLYLGSMAVSDLLILL-GLPFDLYRLWRSRPWVFGPLLCRLSLYVGEGCTYATL
::: :: :: :.::::::.:: :::..::..:.. :...: : . . : :..
XP_006 AMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHNYPFLLGVGGCYFRTLLFEMVCLASV
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB7 LHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVEQDPGIS
:..::::::::.:. .::.:: .::: .:: .....:..:.: . : : :..: .
XP_006 LNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQ---LH
150 160 170 180 190 200
190 200 210 220 230 240
pF1KB7 VVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPAQLGALR
: : :: :. .. :: ::
XP_006 V------------------------------PCRGPVPDSAVCML---VRPR-----ALY
210 220
250 260 270 280
pF1KB7 VMLWVTTA--YFFLPFLCLSILYGLIGRELWSSRRPL------RGPAAS---------GR
:. ::: .: ::. .:.:: ::: .: : : :: ::. .
XP_006 NMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQH
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB7 ERGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSAS
.::.::....: :
XP_006 DRGRRQVTKMLWVKEFWTLSTADIYWYMMDQASWVTQRGTCIWSK
290 300 310 320 330
412 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 07:41:16 2016 done: Fri Nov 4 07:41:18 2016
Total Scan time: 9.900 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]