FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7427, 152 aa 1>>>pF1KB7427 152 - 152 aa - 152 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3368+/-0.000844; mu= 11.2517+/- 0.051 mean_var=58.7014+/-11.665, 0's: 0 Z-trim(105.6): 53 B-trim: 172 in 1/51 Lambda= 0.167398 statistics sampled from 8452 (8506) to 8452 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.261), width: 16 Scan time: 1.670 The best scores are: opt bits E(32554) CCDS41448.1 RGS21 gene_id:431704|Hs108|chr1 ( 152) 1024 255.4 1e-68 CCDS1377.1 RGS2 gene_id:5997|Hs108|chr1 ( 211) 535 137.3 4.8e-33 CCDS1375.2 RGS1 gene_id:5996|Hs108|chr1 ( 209) 519 133.5 6.9e-32 CCDS41443.1 RGS8 gene_id:85397|Hs108|chr1 ( 180) 509 131.0 3.2e-31 CCDS1349.1 RGS8 gene_id:85397|Hs108|chr1 ( 198) 509 131.0 3.5e-31 CCDS1244.1 RGS5 gene_id:8490|Hs108|chr1 ( 181) 503 129.6 8.8e-31 CCDS1374.1 RGS18 gene_id:64407|Hs108|chr1 ( 235) 491 126.7 8.3e-30 CCDS58041.1 RGS5 gene_id:8490|Hs108|chr1 ( 185) 485 125.2 1.8e-29 CCDS44272.1 RGS4 gene_id:5999|Hs108|chr1 ( 187) 477 123.3 7.1e-29 CCDS1243.1 RGS4 gene_id:5999|Hs108|chr1 ( 205) 477 123.3 7.7e-29 CCDS44270.1 RGS4 gene_id:5999|Hs108|chr1 ( 302) 477 123.4 1.1e-28 CCDS35114.1 RGS3 gene_id:5998|Hs108|chr9 ( 311) 464 120.2 9.8e-28 CCDS6798.1 RGS3 gene_id:5998|Hs108|chr9 ( 519) 464 120.3 1.5e-27 CCDS65111.1 RGS3 gene_id:5998|Hs108|chr9 ( 591) 464 120.3 1.7e-27 CCDS6797.1 RGS3 gene_id:5998|Hs108|chr9 ( 917) 464 120.4 2.6e-27 CCDS43869.1 RGS3 gene_id:5998|Hs108|chr9 (1198) 464 120.4 3.3e-27 CCDS1348.1 RGS16 gene_id:6004|Hs108|chr1 ( 202) 451 117.0 5.9e-27 CCDS5244.1 RGS17 gene_id:26575|Hs108|chr6 ( 210) 440 114.4 3.8e-26 CCDS6156.1 RGS20 gene_id:8601|Hs108|chr8 ( 241) 428 111.5 3.2e-25 CCDS69482.1 RGS20 gene_id:8601|Hs108|chr8 ( 273) 428 111.5 3.6e-25 CCDS1376.1 RGS13 gene_id:6003|Hs108|chr1 ( 159) 425 110.7 3.7e-25 CCDS6155.1 RGS20 gene_id:8601|Hs108|chr8 ( 388) 428 111.6 4.9e-25 CCDS13555.1 RGS19 gene_id:10287|Hs108|chr20 ( 217) 396 103.8 6.2e-23 CCDS60457.1 RGS7 gene_id:6000|Hs108|chr1 ( 424) 347 92.0 4.1e-19 CCDS60459.1 RGS7 gene_id:6000|Hs108|chr1 ( 477) 347 92.1 4.6e-19 CCDS41572.1 RGS10 gene_id:6001|Hs108|chr10 ( 167) 336 89.2 1.1e-18 CCDS31294.1 RGS10 gene_id:6001|Hs108|chr10 ( 181) 336 89.2 1.2e-18 CCDS60458.1 RGS7 gene_id:6000|Hs108|chr1 ( 469) 341 90.6 1.2e-18 CCDS31071.1 RGS7 gene_id:6000|Hs108|chr1 ( 487) 341 90.6 1.3e-18 CCDS55924.1 RGS6 gene_id:9628|Hs108|chr14 ( 490) 331 88.2 6.9e-18 CCDS45764.1 RGS9 gene_id:8787|Hs108|chr17 ( 671) 328 87.5 1.5e-17 CCDS42373.1 RGS9 gene_id:8787|Hs108|chr17 ( 674) 328 87.5 1.5e-17 CCDS73655.1 RGS6 gene_id:9628|Hs108|chr14 ( 437) 322 86.0 2.8e-17 CCDS9808.1 RGS6 gene_id:9628|Hs108|chr14 ( 472) 322 86.0 3e-17 CCDS55652.1 RGS5 gene_id:8490|Hs108|chr1 ( 73) 282 76.1 4.6e-15 CCDS10403.1 RGS11 gene_id:8786|Hs108|chr16 ( 446) 287 77.5 1e-14 CCDS66884.1 RGS11 gene_id:8786|Hs108|chr16 ( 456) 287 77.6 1e-14 CCDS42088.1 RGS11 gene_id:8786|Hs108|chr16 ( 467) 287 77.6 1e-14 CCDS43405.1 RGS14 gene_id:10636|Hs108|chr5 ( 566) 280 75.9 4e-14 CCDS3368.1 RGS12 gene_id:6002|Hs108|chr4 ( 799) 272 74.0 2.1e-13 CCDS3367.1 RGS12 gene_id:6002|Hs108|chr4 (1376) 272 74.1 3.4e-13 CCDS3366.1 RGS12 gene_id:6002|Hs108|chr4 (1447) 272 74.1 3.5e-13 CCDS10406.1 AXIN1 gene_id:8312|Hs108|chr16 ( 826) 239 66.1 5.3e-11 CCDS10405.1 AXIN1 gene_id:8312|Hs108|chr16 ( 862) 239 66.1 5.5e-11 >>CCDS41448.1 RGS21 gene_id:431704|Hs108|chr1 (152 aa) initn: 1024 init1: 1024 opt: 1024 Z-score: 1347.3 bits: 255.4 E(32554): 1e-68 Smith-Waterman score: 1024; 100.0% identity (100.0% similar) in 152 aa overlap (1-152:1-152) 10 20 30 40 50 60 pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIFLKSEFSEENVEFWLACEDFKKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIFLKSEFSEENVEFWLACEDFKKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISKNIAEPTLKCFDEAQKLIYCLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 KNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISKNIAEPTLKCFDEAQKLIYCLMA 70 80 90 100 110 120 130 140 150 pF1KB7 KDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL :::::::::::::::::::::::::::::::: CCDS41 KDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL 130 140 150 >>CCDS1377.1 RGS2 gene_id:5997|Hs108|chr1 (211 aa) initn: 545 init1: 524 opt: 535 Z-score: 706.8 bits: 137.3 E(32554): 4.8e-33 Smith-Waterman score: 535; 58.1% identity (78.7% similar) in 136 aa overlap (7-142:69-204) 10 20 30 pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFR : . :.. ::: .: :::.. :: ::: CCDS13 KDWKTRLSYFLQNSSTPGKPKTGKKSKQQAFIKPSPEEAQLWSEAFDELLASKYGLAAFR 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB7 IFLKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLI :::::: :::.:::::::::::::. .:..:::. ::..::: .::::::::: :. :: CCDS13 AFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLI 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB7 SKNIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL ..:: : : :: ::: .: :: ..:.::::.::.:. : .. :. CCDS13 AQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCKKPQITTEPHAT 160 170 180 190 200 210 >>CCDS1375.2 RGS1 gene_id:5996|Hs108|chr1 (209 aa) initn: 534 init1: 288 opt: 519 Z-score: 686.0 bits: 133.5 E(32554): 6.9e-32 Smith-Waterman score: 519; 59.0% identity (81.3% similar) in 134 aa overlap (13-146:77-209) 10 20 30 40 pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIFLKSE ::.: ::.... :::::.: ..: ::::: CCDS13 GMDMKAYLRSMIPHLESGMKSSKSKDVLSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSE 50 60 70 80 90 100 50 60 70 80 90 100 pF1KB7 FSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISKNIAE :::::.::::::::.:::.. : . ::. ::. :...:: :.::::: ::. .:.: CCDS13 FSEENIEFWLACEDYKKTES-DLLPCKAEEIYKAFVHSDAAKQINIDFRTRESTAKKIKA 110 120 130 140 150 160 110 120 130 140 150 pF1KB7 PTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL :: :::::::.:: :: :::.::::::.:: .:.:. :. . : CCDS13 PTPTCFDEAQKVIYTLMEKDSYPRFLKSDIYLNLLNDLQANSLK 170 180 190 200 >>CCDS41443.1 RGS8 gene_id:85397|Hs108|chr1 (180 aa) initn: 471 init1: 471 opt: 509 Z-score: 674.0 bits: 131.0 E(32554): 3.2e-31 Smith-Waterman score: 509; 52.6% identity (82.7% similar) in 133 aa overlap (9-141:44-176) 10 20 30 pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIF : : :. :....:.::... :. ::: : CCDS41 RTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAF 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB7 LKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISK ::.::::::.:::::::.::::... :..:::. :. ::....::.:.:::: ::. : CCDS41 LKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRK 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB7 NIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL :. ::.: :::.:: .. :: :::.::::.:..: :....: CCDS41 NLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS 140 150 160 170 180 >>CCDS1349.1 RGS8 gene_id:85397|Hs108|chr1 (198 aa) initn: 484 init1: 471 opt: 509 Z-score: 673.3 bits: 131.0 E(32554): 3.5e-31 Smith-Waterman score: 509; 52.6% identity (82.7% similar) in 133 aa overlap (9-141:62-194) 10 20 30 pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIF : : :. :....:.::... :. ::: : CCDS13 RTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAF 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB7 LKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISK ::.::::::.:::::::.::::... :..:::. :. ::....::.:.:::: ::. : CCDS13 LKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRK 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB7 NIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL :. ::.: :::.:: .. :: :::.::::.:..: :....: CCDS13 NLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS 160 170 180 190 >>CCDS1244.1 RGS5 gene_id:8490|Hs108|chr1 (181 aa) initn: 500 init1: 467 opt: 503 Z-score: 666.1 bits: 129.6 E(32554): 8.8e-31 Smith-Waterman score: 503; 55.0% identity (81.4% similar) in 129 aa overlap (9-137:52-180) 10 20 30 pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIF .. :.. : ...: :: :. :: .:. : CCDS12 KLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSF 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB7 LKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISK :::::::::.:::.::::.:: :. :.: :::.:: :::...::::.::: :.:. : CCDS12 LKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMK 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB7 NIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL :..::.:. :: ::: :. :: :::.:::..::.:..:. CCDS12 NLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK 150 160 170 180 >>CCDS1374.1 RGS18 gene_id:64407|Hs108|chr1 (235 aa) initn: 481 init1: 451 opt: 491 Z-score: 648.6 bits: 126.7 E(32554): 8.3e-30 Smith-Waterman score: 491; 53.3% identity (83.2% similar) in 137 aa overlap (10-145:76-211) 10 20 30 pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIFL :: :.. :.:..: ::... ::.:: :: CCDS13 NRLSLLVQKPEFHEDTRSSRSGHLAKETRVSPE-EAVKWGESFDKLLSHRDGLEAFTRFL 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB7 KSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISKN :.::::::.:::.:::::::.:. ..: ::: :: .::..:::::.:.:: :...:... CCDS13 KTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNS 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB7 IAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQ-QVPNHKKWLPFL :..:::. :: ::. .: :: .::. :::::.:: :.... : :.. CCDS13 ITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRPQRPTNLRRRSRSFTCNEF 170 180 190 200 210 220 CCDS13 QDVQSDVAIWL 230 >>CCDS58041.1 RGS5 gene_id:8490|Hs108|chr1 (185 aa) initn: 455 init1: 276 opt: 485 Z-score: 642.4 bits: 125.2 E(32554): 1.8e-29 Smith-Waterman score: 485; 53.4% identity (78.9% similar) in 133 aa overlap (9-137:52-184) 10 20 30 pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIF .. :.. : ...: :: :. :: .:. : CCDS58 KLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSF 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB7 LKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEI----NIDFGTRD :::::::::.:::.::::.:: :. :.: :::.:: :::...::::. ::: :.: CCDS58 LKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVGLWVNIDHFTKD 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB7 LISKNIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL . ::..::.:. :: ::: :. :: :::.:::..::.:..:. CCDS58 ITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK 150 160 170 180 >>CCDS44272.1 RGS4 gene_id:5999|Hs108|chr1 (187 aa) initn: 472 init1: 472 opt: 477 Z-score: 631.9 bits: 123.3 E(32554): 7.1e-29 Smith-Waterman score: 477; 49.6% identity (77.7% similar) in 139 aa overlap (9-147:32-170) 10 20 30 pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIF : :. :.:....:.... :: ::. : CCDS44 KHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAF 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 LKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISK ::::.::::..::..::..:: :. .:.. ::: ::.::: ..: ::.:.: ::. :. CCDS44 LKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSR 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 NIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL :. :::. ::::::: :. :: :::. :::::..: ::: .. .:. CCDS44 NMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCAS 130 140 150 160 170 180 CCDS44 LVPQCA >>CCDS1243.1 RGS4 gene_id:5999|Hs108|chr1 (205 aa) initn: 472 init1: 472 opt: 477 Z-score: 631.3 bits: 123.3 E(32554): 7.7e-29 Smith-Waterman score: 477; 49.6% identity (77.7% similar) in 139 aa overlap (9-147:50-188) 10 20 30 pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIF : :. :.:....:.... :: ::. : CCDS12 KHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAF 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB7 LKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISK ::::.::::..::..::..:: :. .:.. ::: ::.::: ..: ::.:.: ::. :. CCDS12 LKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSR 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB7 NIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL :. :::. ::::::: :. :: :::. :::::..: ::: .. .:. CCDS12 NMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCAS 140 150 160 170 180 190 CCDS12 LVPQCA 200 152 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 07:41:51 2016 done: Fri Nov 4 07:41:52 2016 Total Scan time: 1.670 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]