FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7427, 152 aa
1>>>pF1KB7427 152 - 152 aa - 152 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3896+/-0.000384; mu= 10.9521+/- 0.023
mean_var=62.2369+/-12.377, 0's: 0 Z-trim(112.3): 159 B-trim: 716 in 1/54
Lambda= 0.162574
statistics sampled from 21021 (21210) to 21021 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.249), width: 16
Scan time: 4.860
The best scores are: opt bits E(85289)
NP_001034241 (OMIM: 612407) regulator of G-protein ( 152) 1024 248.6 2.9e-66
NP_002914 (OMIM: 600861) regulator of G-protein si ( 211) 535 134.0 1.3e-31
NP_002913 (OMIM: 600323) regulator of G-protein si ( 209) 519 130.2 1.7e-30
XP_011508393 (OMIM: 607189) PREDICTED: regulator o ( 178) 509 127.8 7.6e-30
NP_001095920 (OMIM: 607189) regulator of G-protein ( 180) 509 127.8 7.7e-30
XP_011508392 (OMIM: 607189) PREDICTED: regulator o ( 180) 509 127.8 7.7e-30
XP_016858125 (OMIM: 607189) PREDICTED: regulator o ( 180) 509 127.8 7.7e-30
XP_005245612 (OMIM: 607189) PREDICTED: regulator o ( 180) 509 127.8 7.7e-30
XP_016858124 (OMIM: 607189) PREDICTED: regulator o ( 180) 509 127.8 7.7e-30
XP_016858126 (OMIM: 607189) PREDICTED: regulator o ( 180) 509 127.8 7.7e-30
XP_016858121 (OMIM: 607189) PREDICTED: regulator o ( 198) 509 127.8 8.4e-30
NP_203131 (OMIM: 607189) regulator of G-protein si ( 198) 509 127.8 8.4e-30
XP_016858122 (OMIM: 607189) PREDICTED: regulator o ( 198) 509 127.8 8.4e-30
XP_016858120 (OMIM: 607189) PREDICTED: regulator o ( 198) 509 127.8 8.4e-30
XP_011508391 (OMIM: 607189) PREDICTED: regulator o ( 198) 509 127.8 8.4e-30
XP_016858123 (OMIM: 607189) PREDICTED: regulator o ( 198) 509 127.8 8.4e-30
NP_003608 (OMIM: 145500,603276) regulator of G-pro ( 181) 503 126.4 2.1e-29
NP_570138 (OMIM: 607192) regulator of G-protein si ( 235) 491 123.7 1.8e-28
NP_001241678 (OMIM: 145500,603276) regulator of G- ( 185) 485 122.2 3.9e-28
NP_001106851 (OMIM: 602516) regulator of G-protein ( 187) 477 120.3 1.4e-27
NP_005604 (OMIM: 602516) regulator of G-protein si ( 205) 477 120.3 1.6e-27
NP_001095915 (OMIM: 602516) regulator of G-protein ( 302) 477 120.4 2.2e-27
NP_001263191 (OMIM: 602189) regulator of G-protein ( 168) 464 117.3 1.1e-26
NP_602299 (OMIM: 602189) regulator of G-protein si ( 168) 464 117.3 1.1e-26
NP_652760 (OMIM: 602189) regulator of G-protein si ( 311) 464 117.4 1.9e-26
XP_016870494 (OMIM: 602189) PREDICTED: regulator o ( 519) 464 117.5 2.9e-26
XP_011517199 (OMIM: 602189) PREDICTED: regulator o ( 519) 464 117.5 2.9e-26
NP_001269851 (OMIM: 602189) regulator of G-protein ( 519) 464 117.5 2.9e-26
XP_016870495 (OMIM: 602189) PREDICTED: regulator o ( 519) 464 117.5 2.9e-26
XP_011517198 (OMIM: 602189) PREDICTED: regulator o ( 519) 464 117.5 2.9e-26
XP_006717293 (OMIM: 602189) PREDICTED: regulator o ( 519) 464 117.5 2.9e-26
XP_011517203 (OMIM: 602189) PREDICTED: regulator o ( 519) 464 117.5 2.9e-26
XP_006717289 (OMIM: 602189) PREDICTED: regulator o ( 519) 464 117.5 2.9e-26
NP_001263189 (OMIM: 602189) regulator of G-protein ( 519) 464 117.5 2.9e-26
XP_011517200 (OMIM: 602189) PREDICTED: regulator o ( 519) 464 117.5 2.9e-26
XP_011517202 (OMIM: 602189) PREDICTED: regulator o ( 519) 464 117.5 2.9e-26
XP_006717288 (OMIM: 602189) PREDICTED: regulator o ( 521) 464 117.5 2.9e-26
NP_001309144 (OMIM: 602189) regulator of G-protein ( 537) 464 117.5 3e-26
XP_011517196 (OMIM: 602189) PREDICTED: regulator o ( 545) 464 117.5 3.1e-26
NP_001263190 (OMIM: 602189) regulator of G-protein ( 591) 464 117.5 3.3e-26
XP_006717285 (OMIM: 602189) PREDICTED: regulator o ( 824) 464 117.5 4.4e-26
NP_570613 (OMIM: 602189) regulator of G-protein si ( 917) 464 117.6 4.8e-26
XP_016870493 (OMIM: 602189) PREDICTED: regulator o ( 961) 464 117.6 5e-26
XP_006717283 (OMIM: 602189) PREDICTED: regulator o (1086) 464 117.6 5.6e-26
NP_001269852 (OMIM: 602189) regulator of G-protein (1088) 464 117.6 5.6e-26
XP_006717282 (OMIM: 602189) PREDICTED: regulator o (1094) 464 117.6 5.6e-26
XP_016870492 (OMIM: 602189) PREDICTED: regulator o (1157) 464 117.6 5.9e-26
NP_652759 (OMIM: 602189) regulator of G-protein si (1198) 464 117.6 6.1e-26
NP_002919 (OMIM: 602514) regulator of G-protein si ( 202) 451 114.2 1.1e-25
XP_011508193 (OMIM: 607192) PREDICTED: regulator o ( 144) 443 112.3 2.9e-25
>>NP_001034241 (OMIM: 612407) regulator of G-protein sig (152 aa)
initn: 1024 init1: 1024 opt: 1024 Z-score: 1310.6 bits: 248.6 E(85289): 2.9e-66
Smith-Waterman score: 1024; 100.0% identity (100.0% similar) in 152 aa overlap (1-152:1-152)
10 20 30 40 50 60
pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIFLKSEFSEENVEFWLACEDFKKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIFLKSEFSEENVEFWLACEDFKKT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 KNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISKNIAEPTLKCFDEAQKLIYCLMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISKNIAEPTLKCFDEAQKLIYCLMA
70 80 90 100 110 120
130 140 150
pF1KB7 KDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL
::::::::::::::::::::::::::::::::
NP_001 KDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL
130 140 150
>>NP_002914 (OMIM: 600861) regulator of G-protein signal (211 aa)
initn: 545 init1: 524 opt: 535 Z-score: 688.6 bits: 134.0 E(85289): 1.3e-31
Smith-Waterman score: 535; 58.1% identity (78.7% similar) in 136 aa overlap (7-142:69-204)
10 20 30
pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFR
: . :.. ::: .: :::.. :: :::
NP_002 KDWKTRLSYFLQNSSTPGKPKTGKKSKQQAFIKPSPEEAQLWSEAFDELLASKYGLAAFR
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB7 IFLKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLI
:::::: :::.:::::::::::::. .:..:::. ::..::: .::::::::: :. ::
NP_002 AFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLI
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB7 SKNIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL
..:: : : :: ::: .: :: ..:.::::.::.:. : .. :.
NP_002 AQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCKKPQITTEPHAT
160 170 180 190 200 210
>>NP_002913 (OMIM: 600323) regulator of G-protein signal (209 aa)
initn: 534 init1: 288 opt: 519 Z-score: 668.3 bits: 130.2 E(85289): 1.7e-30
Smith-Waterman score: 519; 59.0% identity (81.3% similar) in 134 aa overlap (13-146:77-209)
10 20 30 40
pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIFLKSE
::.: ::.... :::::.: ..: :::::
NP_002 GMDMKAYLRSMIPHLESGMKSSKSKDVLSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSE
50 60 70 80 90 100
50 60 70 80 90 100
pF1KB7 FSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISKNIAE
:::::.::::::::.:::.. : . ::. ::. :...:: :.::::: ::. .:.:
NP_002 FSEENIEFWLACEDYKKTES-DLLPCKAEEIYKAFVHSDAAKQINIDFRTRESTAKKIKA
110 120 130 140 150 160
110 120 130 140 150
pF1KB7 PTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL
:: :::::::.:: :: :::.::::::.:: .:.:. :. . :
NP_002 PTPTCFDEAQKVIYTLMEKDSYPRFLKSDIYLNLLNDLQANSLK
170 180 190 200
>>XP_011508393 (OMIM: 607189) PREDICTED: regulator of G- (178 aa)
initn: 484 init1: 471 opt: 509 Z-score: 656.8 bits: 127.8 E(85289): 7.6e-30
Smith-Waterman score: 509; 52.6% identity (82.7% similar) in 133 aa overlap (9-141:42-174)
10 20 30
pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIF
: : :. :....:.::... :. ::: :
XP_011 RTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAF
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB7 LKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISK
::.::::::.:::::::.::::... :..:::. :. ::....::.:.:::: ::. :
XP_011 LKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRK
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB7 NIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL
:. ::.: :::.:: .. :: :::.::::.:..: :....:
XP_011 NLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
140 150 160 170
>>NP_001095920 (OMIM: 607189) regulator of G-protein sig (180 aa)
initn: 471 init1: 471 opt: 509 Z-score: 656.7 bits: 127.8 E(85289): 7.7e-30
Smith-Waterman score: 509; 52.6% identity (82.7% similar) in 133 aa overlap (9-141:44-176)
10 20 30
pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIF
: : :. :....:.::... :. ::: :
NP_001 RTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAF
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB7 LKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISK
::.::::::.:::::::.::::... :..:::. :. ::....::.:.:::: ::. :
NP_001 LKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRK
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB7 NIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL
:. ::.: :::.:: .. :: :::.::::.:..: :....:
NP_001 NLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
140 150 160 170 180
>>XP_011508392 (OMIM: 607189) PREDICTED: regulator of G- (180 aa)
initn: 471 init1: 471 opt: 509 Z-score: 656.7 bits: 127.8 E(85289): 7.7e-30
Smith-Waterman score: 509; 52.6% identity (82.7% similar) in 133 aa overlap (9-141:44-176)
10 20 30
pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIF
: : :. :....:.::... :. ::: :
XP_011 RTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAF
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB7 LKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISK
::.::::::.:::::::.::::... :..:::. :. ::....::.:.:::: ::. :
XP_011 LKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRK
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB7 NIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL
:. ::.: :::.:: .. :: :::.::::.:..: :....:
XP_011 NLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
140 150 160 170 180
>>XP_016858125 (OMIM: 607189) PREDICTED: regulator of G- (180 aa)
initn: 471 init1: 471 opt: 509 Z-score: 656.7 bits: 127.8 E(85289): 7.7e-30
Smith-Waterman score: 509; 52.6% identity (82.7% similar) in 133 aa overlap (9-141:44-176)
10 20 30
pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIF
: : :. :....:.::... :. ::: :
XP_016 RTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAF
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB7 LKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISK
::.::::::.:::::::.::::... :..:::. :. ::....::.:.:::: ::. :
XP_016 LKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRK
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB7 NIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL
:. ::.: :::.:: .. :: :::.::::.:..: :....:
XP_016 NLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
140 150 160 170 180
>>XP_005245612 (OMIM: 607189) PREDICTED: regulator of G- (180 aa)
initn: 471 init1: 471 opt: 509 Z-score: 656.7 bits: 127.8 E(85289): 7.7e-30
Smith-Waterman score: 509; 52.6% identity (82.7% similar) in 133 aa overlap (9-141:44-176)
10 20 30
pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIF
: : :. :....:.::... :. ::: :
XP_005 RTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAF
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB7 LKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISK
::.::::::.:::::::.::::... :..:::. :. ::....::.:.:::: ::. :
XP_005 LKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRK
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB7 NIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL
:. ::.: :::.:: .. :: :::.::::.:..: :....:
XP_005 NLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
140 150 160 170 180
>>XP_016858124 (OMIM: 607189) PREDICTED: regulator of G- (180 aa)
initn: 471 init1: 471 opt: 509 Z-score: 656.7 bits: 127.8 E(85289): 7.7e-30
Smith-Waterman score: 509; 52.6% identity (82.7% similar) in 133 aa overlap (9-141:44-176)
10 20 30
pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIF
: : :. :....:.::... :. ::: :
XP_016 RTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAF
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB7 LKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISK
::.::::::.:::::::.::::... :..:::. :. ::....::.:.:::: ::. :
XP_016 LKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRK
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB7 NIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL
:. ::.: :::.:: .. :: :::.::::.:..: :....:
XP_016 NLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
140 150 160 170 180
>>XP_016858126 (OMIM: 607189) PREDICTED: regulator of G- (180 aa)
initn: 471 init1: 471 opt: 509 Z-score: 656.7 bits: 127.8 E(85289): 7.7e-30
Smith-Waterman score: 509; 52.6% identity (82.7% similar) in 133 aa overlap (9-141:44-176)
10 20 30
pF1KB7 MPVKCCFYRSPTAETMTWSENMDTLLANQAGLDAFRIF
: : :. :....:.::... :. ::: :
XP_016 RTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAF
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB7 LKSEFSEENVEFWLACEDFKKTKNADKIASKAKMIYSEFIEADAPKEINIDFGTRDLISK
::.::::::.:::::::.::::... :..:::. :. ::....::.:.:::: ::. :
XP_016 LKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRK
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB7 NIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIYKKLVNSQQVPNHKKWLPFL
:. ::.: :::.:: .. :: :::.::::.:..: :....:
XP_016 NLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
140 150 160 170 180
152 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 07:41:52 2016 done: Fri Nov 4 07:41:53 2016
Total Scan time: 4.860 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]