FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7429, 299 aa
  1>>>pF1KB7429 299 - 299 aa - 299 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1704+/-0.000307; mu= 16.0911+/- 0.019
 mean_var=63.7777+/-12.699, 0's: 0 Z-trim(116.8): 14  B-trim: 0 in 0/50
 Lambda= 0.160598
 statistics sampled from 28315 (28326) to 28315 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.332), width:  16
 Scan time:  7.550

The best scores are:                                      opt bits E(85289)
NP_658985 (OMIM: 608862) NAD(P)H-hydrate epimerase ( 288)  773 187.4 2.8e-47
XP_016855808 (OMIM: 608862) PREDICTED: NAD(P)H-hyd ( 306)  537 132.7 8.6e-31


>>NP_658985 (OMIM: 608862) NAD(P)H-hydrate epimerase pre  (288 aa)
 initn: 741 init1: 455 opt: 773  Z-score: 969.7  bits: 187.4 E(85289): 2.8e-47
Smith-Waterman score: 773; 47.5% identity (74.9% similar) in 255 aa overlap (47-299:39-287)

         20        30        40        50        60          70    
pF1KB7 HFLRALELQPPLADMGRAELSSNATTSLVQRRKQAWGRQSWLEQIWNAGPVCQ--STAEA
                                     .: .. ::  :  ..  :. : .  :  ::
NP_658 GLGLLVAGSRVPRIKSQTIACRSGPTWWGPQRLNSGGR--WDSEVM-ASTVVKYLSQEEA
       10        20        30        40          50         60     

           80        90       100       110       120       130    
pF1KB7 AALERELLEDYRFGRQQLVELCGHASAVAVTKAFPLPALSRKQRTVLVVCGPEQNGAVGL
        :...::...:.:. .::.:: : . :.:..::.:  ..::.  ::::.::: .::. ::
NP_658 QAVDQELFNEYQFSVDQLMELAGLSCATAIAKAYPPTSMSRSPPTVLVICGPGNNGGDGL
          70        80        90       100       110       120     

          140       150       160       170       180       190    
pF1KB7 VCARHLRVFEYEPTIFYPTRSLDLLHRDLTTQCEKMDIPFLSYLPTEVQLINEAYGLVVD
       ::::::..: :::::.:: :    :   :.:::.:::::::. .:.: . :.: : ::::
NP_658 VCARHLKLFGYEPTIYYPKRPNKPLFTALVTQCQKMDIPFLGEMPAEPMTIDELYELVVD
         130       140       150       160       170       180     

          200       210       220       230       240       250    
pF1KB7 AVLGPGVEPGEVGGPCTRALATLKLLSIPLVSLDIPSGWDAETGSDSEDGLRPDVLVSLA
       :..: . . :.:  :    :..:: :..:..:.:::::::.: :. .  :..::.:.::.
NP_658 AIFGFSFK-GDVREPFHSILSVLKGLTVPIASIDIPSGWDVEKGNAG--GIQPDLLISLT
         190        200       210       220       230         240  

          260       270       280       290          
pF1KB7 APKRCAGRFSGRHHFVAGRFVPDDVRRKFALRLPGYTGTDCVAAL 
       :::. : .:.::.:...:::::  ...:. : :: :  :.::  : 
NP_658 APKKSATQFTGRYHYLGGRFVPPALEKKYQLNLPPYPDTECVYRLQ
            250       260       270       280        

>>XP_016855808 (OMIM: 608862) PREDICTED: NAD(P)H-hydrate  (306 aa)
 initn: 520 init1: 455 opt: 537  Z-score: 673.8  bits: 132.7 E(85289): 8.6e-31
Smith-Waterman score: 537; 47.3% identity (73.9% similar) in 188 aa overlap (47-232:39-222)

         20        30        40        50        60          70    
pF1KB7 HFLRALELQPPLADMGRAELSSNATTSLVQRRKQAWGRQSWLEQIWNAGPVCQ--STAEA
                                     .: .. ::  :  ..  :. : .  :  ::
XP_016 GLGLLVAGSRVPRIKSQTIACRSGPTWWGPQRLNSGGR--WDSEVM-ASTVVKYLSQEEA
       10        20        30        40          50         60     

           80        90       100       110       120       130    
pF1KB7 AALERELLEDYRFGRQQLVELCGHASAVAVTKAFPLPALSRKQRTVLVVCGPEQNGAVGL
        :...::...:.:. .::.:: : . :.:..::.:  ..::.  ::::.::: .::. ::
XP_016 QAVDQELFNEYQFSVDQLMELAGLSCATAIAKAYPPTSMSRSPPTVLVICGPGNNGGDGL
          70        80        90       100       110       120     

          140       150       160       170       180       190    
pF1KB7 VCARHLRVFEYEPTIFYPTRSLDLLHRDLTTQCEKMDIPFLSYLPTEVQLINEAYGLVVD
       ::::::..: :::::.:: :    :   :.:::.:::::::. .:.: . :.: : ::::
XP_016 VCARHLKLFGYEPTIYYPKRPNKPLFTALVTQCQKMDIPFLGEMPAEPMTIDELYELVVD
         130       140       150       160       170       180     

          200       210       220       230       240       250    
pF1KB7 AVLGPGVEPGEVGGPCTRALATLKLLSIPLVSLDIPSGWDAETGSDSEDGLRPDVLVSLA
       :..: . . :.:  :    :..:: :..:..:.:::::                      
XP_016 AIFGFSFK-GDVREPFHSILSVLKGLTVPIASIDIPSGAGIQKLAGEQNKKRKCSGSSGL
         190        200       210       220       230       240    

          260       270       280       290                        
pF1KB7 APKRCAGRFSGRHHFVAGRFVPDDVRRKFALRLPGYTGTDCVAAL               
                                                                   
XP_016 HSGQVPVTDSKDAPLHPDHSTCSQYLHLIRLIESLLWAKELGIQSGIRMRWAQPRWNLHR
          250       260       270       280       290       300    




299 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 07:42:57 2016 done: Fri Nov  4 07:42:58 2016
 Total Scan time:  7.550 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]