FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7430, 496 aa 1>>>pF1KB7430 496 - 496 aa - 496 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3054+/-0.00088; mu= 8.7421+/- 0.053 mean_var=105.0125+/-20.828, 0's: 0 Z-trim(109.0): 25 B-trim: 0 in 0/51 Lambda= 0.125157 statistics sampled from 10542 (10563) to 10542 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.324), width: 16 Scan time: 3.040 The best scores are: opt bits E(32554) CCDS5119.2 CEP85L gene_id:387119|Hs108|chr6 ( 496) 3298 606.1 2.8e-173 CCDS43498.1 CEP85L gene_id:387119|Hs108|chr6 ( 805) 3189 586.5 3.7e-167 CCDS55052.1 CEP85L gene_id:387119|Hs108|chr6 ( 808) 3014 554.9 1.2e-157 CCDS60038.1 CEP85 gene_id:64793|Hs108|chr1 ( 711) 312 67.0 7.9e-11 >>CCDS5119.2 CEP85L gene_id:387119|Hs108|chr6 (496 aa) initn: 3298 init1: 3298 opt: 3298 Z-score: 3224.3 bits: 606.1 E(32554): 2.8e-173 Smith-Waterman score: 3298; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496) 10 20 30 40 50 60 pF1KB7 MWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNHIRRHSIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 MWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNHIRRHSIA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSASISKLRESLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 SDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSASISKLRESLTP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 DGSKWSTSLMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNCGQGGTVCREESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 DGSKWSTSLMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNCGQGGTVCREESR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 NGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSKEDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 NGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSKEDF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 RASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMWL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 TEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 TEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKV 430 440 450 460 470 480 490 pF1KB7 GFSNKVELGQQHFLSI :::::::::::::::: CCDS51 GFSNKVELGQQHFLSI 490 >>CCDS43498.1 CEP85L gene_id:387119|Hs108|chr6 (805 aa) initn: 3218 init1: 3189 opt: 3189 Z-score: 3114.5 bits: 586.5 E(32554): 3.7e-167 Smith-Waterman score: 3189; 99.8% identity (100.0% similar) in 480 aa overlap (1-480:1-480) 10 20 30 40 50 60 pF1KB7 MWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNHIRRHSIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNHIRRHSIA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSASISKLRESLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSASISKLRESLTP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 DGSKWSTSLMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNCGQGGTVCREESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DGSKWSTSLMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNCGQGGTVCREESR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 NGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSKEDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 NGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSKEDF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMWL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 TEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 TEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. CCDS43 QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKL 430 440 450 460 470 480 490 pF1KB7 GFSNKVELGQQHFLSI CCDS43 KTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKN 490 500 510 520 530 540 >>CCDS55052.1 CEP85L gene_id:387119|Hs108|chr6 (808 aa) initn: 3043 init1: 3014 opt: 3014 Z-score: 2943.7 bits: 554.9 E(32554): 1.2e-157 Smith-Waterman score: 3014; 99.8% identity (100.0% similar) in 456 aa overlap (25-480:28-483) 10 20 30 40 50 pF1KB7 MWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNHIRRH ::::::::::::::::::::::::::::::::: CCDS55 MIWRNNWKSTTGRLNVKLQSDKLQHGCGPDYSSAWLPANESLWQATTVPSNHRNNHIRRH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 SIASDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSASISKLRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SIASDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSASISKLRES 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 LTPDGSKWSTSLMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNCGQGGTVCRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LTPDGSKWSTSLMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNCGQGGTVCRE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 ESRNGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ESRNGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB7 EDFRASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 EDFRASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB7 MWLTEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MWLTEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDF 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB7 SKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVAS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB7 LQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLE 430 440 450 460 470 480 480 490 pF1KB7 EKVGFSNKVELGQQHFLSI ::. CCDS55 EKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEK 490 500 510 520 530 540 >>CCDS60038.1 CEP85 gene_id:64793|Hs108|chr1 (711 aa) initn: 316 init1: 154 opt: 312 Z-score: 307.9 bits: 67.0 E(32554): 7.9e-11 Smith-Waterman score: 383; 29.1% identity (56.9% similar) in 422 aa overlap (81-485:22-402) 60 70 80 90 100 110 pF1KB7 NNHIRRHSIASDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSAS .:::. :.: .: .:.::::::::. ..: CCDS60 MAMQEKYPTEGISHVTSPNFCSSSGSPPFQPIKSHVTIPTAHVMPSTLGTS 10 20 30 40 50 120 130 140 150 160 pF1KB7 ISKLRES-LTPDGSKWSTS-LMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNC .: . . :..:: : : ...: : :. ... .::. : CCDS60 PAKPNSTPVGPSSSKLPLSGLAESVGMTRNG---------DLGAMKHSPGLSR----DLM 60 70 80 90 170 180 190 200 210 220 pF1KB7 GQGGTVCREESRNGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDC .:.. ..::.:. : . ..: :. .: : : . :::. CCDS60 YFSGAT----GENGIEQ--------SWFPAVG----HERQEEARKFD---IPSMESTLNQ 100 110 120 130 230 240 250 260 270 280 pF1KB7 KYKFESC-SKEDFRASSSTLRRQPVDMTYSALPESKPIMTSSEAFE--PPK-----YLML . .:. : :. . : . : .:::.: :. .:: :. : : CCDS60 SAMMETLYSDPHHRVRFHNPRTSTSKELYRVLPEAKKAPGSGAVFERNGPHSNSSGVLPL 140 150 160 170 180 190 290 300 310 320 330 340 pF1KB7 GQQAVGGVPIQPSVRTQMWLTEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQ : : . :. .: . .:.: . .: . :.: :. .::.: .: : :: CCDS60 GLQPAPGLS-KP-LPSQVW-----QPSPDTWHPREQSCELST-CRQQLELIRLQMEQ-MQ 200 210 220 230 240 250 350 360 370 380 390 pF1KB7 VLTGS---SRQSYSPGYQ--DFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDN . .:. ...:. . ..: :.:. .: ::..::..::.:...:..:....:.. CCDS60 LQNGAICHHPAAFGPSLPILEPAQWISILNSNEHLLKEKELLIDKQRKHISQLEQKVRES 260 270 280 290 300 310 400 410 420 430 440 450 pF1KB7 ELRAQHAMLGHYVNCEDSYVASLQP-QYENTSLQTPFSEESVSHSQQG-EFEQKLASTEK ::... :.::. . : . :: : ::: :.. :.... . :.. ..:.::...: CCDS60 ELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSREKIDLEKKLSASEV 320 330 340 350 360 370 460 470 480 490 pF1KB7 EVLQLNEFLKQRLSLFSEEKKKLEEKVGFSNKVELGQQHFLSI :: . : :: :. ::: :: ::.: .: CCDS60 EVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLER 380 390 400 410 420 430 CCDS60 YLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQRE 440 450 460 470 480 490 496 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 07:43:33 2016 done: Fri Nov 4 07:43:33 2016 Total Scan time: 3.040 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]