FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7431, 308 aa 1>>>pF1KB7431 308 - 308 aa - 308 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0179+/-0.000305; mu= 13.0323+/- 0.019 mean_var=85.7853+/-16.703, 0's: 0 Z-trim(118.0): 30 B-trim: 64 in 1/55 Lambda= 0.138474 statistics sampled from 30402 (30432) to 30402 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.357), width: 16 Scan time: 7.980 The best scores are: opt bits E(85289) NP_003299 (OMIM: 480100) testis-specific Y-encoded ( 308) 2009 410.7 1.9e-114 NP_001184171 (OMIM: 480100) testis-specific Y-enco ( 294) 1770 363.0 4.2e-100 XP_016885553 (OMIM: 480100) PREDICTED: testis-spec ( 288) 1420 293.0 4.7e-79 NP_001307893 (OMIM: 480100) testis-specific Y-enco ( 221) 1292 267.4 1.9e-71 NP_003300 (OMIM: 604714,608800) testis-specific Y- ( 437) 666 142.5 1.5e-33 NP_071400 (OMIM: 300564) testis-specific Y-encoded ( 693) 580 125.4 3.2e-28 XP_006724655 (OMIM: 300564) PREDICTED: testis-spec ( 694) 580 125.4 3.2e-28 NP_277047 (OMIM: 614721) testis-specific Y-encoded ( 417) 552 119.7 1e-26 NP_001234930 (OMIM: 600960) protein SET isoform 4 ( 266) 346 78.4 1.7e-14 NP_001116293 (OMIM: 600960) protein SET isoform 1 ( 290) 341 77.5 3.6e-14 XP_016870503 (OMIM: 600960) PREDICTED: protein SET ( 309) 341 77.5 3.8e-14 XP_016870504 (OMIM: 600960) PREDICTED: protein SET ( 309) 341 77.5 3.8e-14 XP_016870502 (OMIM: 600960) PREDICTED: protein SET ( 309) 341 77.5 3.8e-14 NP_001234929 (OMIM: 600960) protein SET isoform 3 ( 268) 323 73.9 4.1e-13 NP_003002 (OMIM: 600960) protein SET isoform 2 [Ho ( 277) 323 73.9 4.2e-13 XP_016870505 (OMIM: 600960) PREDICTED: protein SET ( 296) 323 73.9 4.5e-13 XP_016885216 (OMIM: 300564) PREDICTED: testis-spec ( 737) 293 68.1 6.1e-11 XP_016885215 (OMIM: 300564) PREDICTED: testis-spec ( 738) 293 68.1 6.1e-11 NP_004529 (OMIM: 300117) nucleosome assembly prote ( 506) 160 41.4 0.0044 >>NP_003299 (OMIM: 480100) testis-specific Y-encoded pro (308 aa) initn: 2009 init1: 2009 opt: 2009 Z-score: 2175.8 bits: 410.7 E(85289): 1.9e-114 Smith-Waterman score: 2009; 98.7% identity (98.7% similar) in 308 aa overlap (1-308:1-308) 10 20 30 40 50 60 pF1KB7 MRPEGSLTYRVPERLRQGSCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALG :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: NP_003 MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVELE :::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::: NP_003 EEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LSYMVSLEVEEEKHRVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPD ::::::::: :::: ::::::::::::::::::::::::::::::::::::::::::::: NP_003 LSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 YEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTET 250 260 270 280 290 300 pF1KB7 SGDSQLLS :::::::: NP_003 SGDSQLLS >>NP_001184171 (OMIM: 480100) testis-specific Y-encoded (294 aa) initn: 1770 init1: 1770 opt: 1770 Z-score: 1918.1 bits: 363.0 E(85289): 4.2e-100 Smith-Waterman score: 1770; 98.5% identity (98.5% similar) in 274 aa overlap (1-274:1-274) 10 20 30 40 50 60 pF1KB7 MRPEGSLTYRVPERLRQGSCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALG :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: NP_001 MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVELE :::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::: NP_001 EEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LSYMVSLEVEEEKHRVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPD ::::::::: :::: ::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 YEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTET :::::::::::::::::::::::::::::::::: NP_001 YEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAESPDRSYVRTCGAIPCNTTRG 250 260 270 280 290 pF1KB7 SGDSQLLS >>XP_016885553 (OMIM: 480100) PREDICTED: testis-specific (288 aa) initn: 1418 init1: 1418 opt: 1420 Z-score: 1540.3 bits: 293.0 E(85289): 4.7e-79 Smith-Waterman score: 1420; 92.2% identity (93.4% similar) in 243 aa overlap (1-239:1-243) 10 20 30 40 50 60 pF1KB7 MRPEGSLTYRVPERLRQGSCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALG :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: XP_016 MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVELE :::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::: XP_016 EEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDM 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LSYMVSLEVEEEKHRVHLCKIMLFFRSNPYFQNKVITKEYLVNIT----EYRASHSTPIE ::::::::: :::: :::::::::::::::::::::::::::::: . : .. XP_016 LSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITGLLIPLQLSGIRIMK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB7 WYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEE : : XP_016 WRPIAADTTTAALTSSTGSLTTTSQDLTRLLRSYVRTCGAIPCNTTRG 250 260 270 280 >>NP_001307893 (OMIM: 480100) testis-specific Y-encoded (221 aa) initn: 1292 init1: 1292 opt: 1292 Z-score: 1403.8 bits: 267.4 E(85289): 1.9e-71 Smith-Waterman score: 1296; 70.8% identity (70.8% similar) in 308 aa overlap (1-308:1-221) 10 20 30 40 50 60 pF1KB7 MRPEGSLTYRVPERLRQGSCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALG :::::::::::::::::: ::::::::::: NP_001 MRPEGSLTYRVPERLRQGFCGVGRAAQALV------------------------------ 10 20 30 70 80 90 100 110 120 pF1KB7 EEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVELE ::: NP_001 ---------------------------------------------------------ELE 130 140 150 160 170 180 pF1KB7 PVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDM 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB7 LSYMVSLEVEEEKHRVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPD ::::::::: :::: ::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPD 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB7 YEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTET 160 170 180 190 200 210 pF1KB7 SGDSQLLS :::::::: NP_001 SGDSQLLS 220 >>NP_003300 (OMIM: 604714,608800) testis-specific Y-enco (437 aa) initn: 626 init1: 626 opt: 666 Z-score: 723.5 bits: 142.5 E(85289): 1.5e-33 Smith-Waterman score: 666; 41.1% identity (68.4% similar) in 275 aa overlap (20-288:135-408) 10 20 30 40 pF1KB7 MRPEGSLTYRVPERLRQGSCGVGRAAQALVCASAKEGTAFRM-EAVQEG ::. :.:. :. .. :. . . . . NP_003 AEGLAAASVVMAADRSLKKGVQGGEKALEICGAQRSASELTAGAEAEAEEVKTGKCATVS 110 120 130 140 150 160 50 60 70 80 90 100 pF1KB7 AAGVESEQAALGEEAVLLLDDIMAEVEVVAEE--EGL-VERREEAQRAQQAVP--GPGPM :: .: :.: . .:. : ..: : : :. :: .: :: . ..: :: :. NP_003 AAVAERESAEVVKEG-LAEKEVMEEQMEVEEQPPEGEEIEVAEEDRLEEEAREEEGPWPL 170 180 190 200 210 220 110 120 130 140 150 160 pF1KB7 TPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVI .. : :.:.::. ::::: .::.. ..:. : :. .:.::. .::..:::: ... NP_003 HEALRMDPLEAIQLELDTVNAQADRAFQQLEHKFGRMRRHYLERRNYIIQNIPGFWMTAF 230 240 250 260 270 280 170 180 190 200 210 220 pF1KB7 ANHPQMSALITDEDEDMLSYMVSLEVEEEKHRVHLCKIMLFFRSNPYFQNKVITKEYLVN ::::.::.: .: .:: :...:::.: .: ::. .::: ::::.::.:.::: : NP_003 RNHPQLSAMIRGQDAEMLRYITNLEVKELRHPRTGCKFKFFFRRNPYFRNKLIVKEYEVR 290 300 310 320 330 340 230 240 250 260 270 280 pF1KB7 ITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRN . .: :::: : .: ... ::... .::.:::::.. :.:::::. .::: : NP_003 SSGRVVSLSTPIIWRRGHEPQSFIRRNQDLICSFFTWFSDHSLPESDKIAEIIKEDLWPN 350 360 370 380 390 400 290 300 pF1KB7 PLQYYKRMKPPEEGTETSGDSQLLS ::::: NP_003 PLQYYLLREGVRRARRRPLREPVEIPRPFGFQSG 410 420 430 >>NP_071400 (OMIM: 300564) testis-specific Y-encoded-lik (693 aa) initn: 599 init1: 572 opt: 580 Z-score: 627.7 bits: 125.4 E(85289): 3.2e-28 Smith-Waterman score: 580; 39.3% identity (69.5% similar) in 239 aa overlap (61-292:166-399) 40 50 60 70 80 pF1KB7 CASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLV---ERR :::.....: : :.:.. .:: NP_071 QSSSFGGEGALETCSAVGWAPQRLVDPKSKEEAIIIVED-----EDEDERESMRSSRRRR 140 150 160 170 180 190 90 100 110 120 130 140 pF1KB7 EEAQRAQQAVPGPG----PMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKP .. .: :. : . :: :. : .:..:: :: .: ::: : ..:. . :.: NP_071 RRRRRKQRKVKRESRERNAERMESILQALEDIQLDLEAVNIKAGKAFLRLKRKFIQMRRP 200 210 220 230 240 250 150 160 170 180 190 200 pF1KB7 HLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHRVHLCKIML :.:: .:: .::::.... :::..: ::. .:::.. :...:.:.. .: :. : NP_071 FLERRDLIIQHIPGFWVKAFLNHPRISILINRRDEDIFRYLTNLQVQDLRHISMGYKMKL 260 270 280 290 300 310 210 220 230 240 250 260 pF1KB7 FFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSD .:..:::: : ::.::. : . .::::::.:. : .: :. ....: .::.:::. NP_071 YFQTNPYFTNMVIVKEFQRNRSGRLVSHSTPIRWHRGQEPQARRHGNQDASHSFFSWFSN 320 330 340 350 360 370 270 280 290 300 pF1KB7 HNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS :.. ...::::. .::: :::.:: : . NP_071 HSLPEADRIAEIIKNDLWVNPLRYYLRERGSRIKRKKQEMKKRKTRGRCEVVIMEDAPDY 380 390 400 410 420 430 >>XP_006724655 (OMIM: 300564) PREDICTED: testis-specific (694 aa) initn: 622 init1: 572 opt: 580 Z-score: 627.7 bits: 125.4 E(85289): 3.2e-28 Smith-Waterman score: 580; 39.3% identity (69.5% similar) in 239 aa overlap (61-292:166-399) 40 50 60 70 80 pF1KB7 CASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLV---ERR :::.....: : :.:.. .:: XP_006 QSSSFGGEGALETCSAVGWAPQRLVDPKSKEEAIIIVED-----EDEDERESMRSSRRRR 140 150 160 170 180 190 90 100 110 120 130 140 pF1KB7 EEAQRAQQAVPGPG----PMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKP .. .: :. : . :: :. : .:..:: :: .: ::: : ..:. . :.: XP_006 RRRRRKQRKVKRESRERNAERMESILQALEDIQLDLEAVNIKAGKAFLRLKRKFIQMRRP 200 210 220 230 240 250 150 160 170 180 190 200 pF1KB7 HLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHRVHLCKIML :.:: .:: .::::.... :::..: ::. .:::.. :...:.:.. .: :. : XP_006 FLERRDLIIQHIPGFWVKAFLNHPRISILINRRDEDIFRYLTNLQVQDLRHISMGYKMKL 260 270 280 290 300 310 210 220 230 240 250 260 pF1KB7 FFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSD .:..:::: : ::.::. : . .::::::.:. : .: :. ....: .::.:::. XP_006 YFQTNPYFTNMVIVKEFQRNRSGRLVSHSTPIRWHRGQEPQARRHGNQDASHSFFSWFSN 320 330 340 350 360 370 270 280 290 300 pF1KB7 HNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS :.. ...::::. .::: :::.:: : . XP_006 HSLPEADRIAEIIKNDLWVNPLRYYLRERGSRIKRKKQEMKKRKTRGRCEVVIMEDAPDY 380 390 400 410 420 430 >>NP_277047 (OMIM: 614721) testis-specific Y-encoded-lik (417 aa) initn: 570 init1: 537 opt: 552 Z-score: 600.7 bits: 119.7 E(85289): 1e-26 Smith-Waterman score: 552; 39.2% identity (70.0% similar) in 227 aa overlap (78-302:173-397) 50 60 70 80 90 100 pF1KB7 GAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPES : :. : :: .. ..: : :: . :. NP_277 GPAGKKAPETCSTAGRGPQVIAGGRQKKGAAGENTSVSAGEEKKEERDA--GSGPPATEG 150 160 170 180 190 200 110 120 130 140 150 160 pF1KB7 ALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHP ... : ::..:: .:::: .:. : .:. . : ::.::. .::..::::.... ::: NP_277 SMDTLENVQLKLENMNAQADRAYLRLSRKFGQLRLQHLERRNHLIQNIPGFWGQAFQNHP 210 220 230 240 250 260 170 180 190 200 210 220 pF1KB7 QMSALITDEDEDMLSYMVSLEVEEEKHRVHLCKIMLFFRSNPYFQNKVITKEYLVNITEY :............:::. :::::: :: ..: ::::::::. ::: . . NP_277 QLASFLNSQEKEVLSYLNSLEVEELGLARLGYKIKFYFDRNPYFQNKVLIKEYGCGPSGQ 270 280 290 300 310 320 230 240 250 260 270 280 pF1KB7 RASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQY .:.::::.: : ..... . . ... .::.:::.:. :.::.::. ..:: ::::. NP_277 VVSRSTPIQWLPGHDLQSLSQGNPENNRSFFGWFSNHSSIESDKIVEIINEELWPNPLQF 330 340 350 360 370 380 290 300 pF1KB7 YKRMKPP--EEGTETSGDSQLLS : . :.: : : NP_277 YLLSEGARVEKGKEKEGRQGPGKQPMETTQPGVSQSN 390 400 410 >>NP_001234930 (OMIM: 600960) protein SET isoform 4 [Hom (266 aa) initn: 448 init1: 312 opt: 346 Z-score: 381.3 bits: 78.4 E(85289): 1.7e-14 Smith-Waterman score: 500; 35.0% identity (66.8% similar) in 226 aa overlap (92-305:4-229) 70 80 90 100 110 120 pF1KB7 EAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVELEP :..: : : . :.:.. :: :.. NP_001 MMPRSHQPPPPPHEKEQQEAIEHIDEVQNEIDR 10 20 30 130 140 150 160 170 180 pF1KB7 VNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDML .: :: . . . ..:... :.: ...:. .: ..:.::.....::::.:::. .:::. : NP_001 LNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEAL 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB7 SYMVSLEVEEEKHRVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDY :.. .:: : . .: ..: ::::.:::..::. .: . .:.:: :.: NP_001 HYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGK 100 110 120 130 140 150 250 260 270 280 290 pF1KB7 EV---------EAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYY--KR .. .: :.:.:. .::.::.::. ::.....:.. :.: :::::: NP_001 DLTKRSSQTQNKASRKRQHEEPESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYLVPD 160 170 180 190 200 210 300 pF1KB7 MKPPE-EGTETSGDSQLLS : : :: : . :.. NP_001 MDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEGEDD 220 230 240 250 260 >>NP_001116293 (OMIM: 600960) protein SET isoform 1 [Hom (290 aa) initn: 448 init1: 312 opt: 341 Z-score: 375.3 bits: 77.5 E(85289): 3.6e-14 Smith-Waterman score: 495; 34.5% identity (66.4% similar) in 229 aa overlap (89-305:25-253) 60 70 80 90 100 110 pF1KB7 LGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVE : :. ..: : . :.:.. :: : NP_001 MAPKRQSPLPPQKKKPRPPPALGPEETSASAGLPKKGEKEQQEAIEHIDEVQNE 10 20 30 40 50 120 130 140 150 160 170 pF1KB7 LEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDE .. .: :: . . . ..:... :.: ...:. .: ..:.::.....::::.:::. .::: NP_001 IDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDE 60 70 80 90 100 110 180 190 200 210 220 230 pF1KB7 DMLSYMVSLEVEEEKHRVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWY . : :.. .:: : . .: ..: ::::.:::..::. .: . .:.:: :.: NP_001 EALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWK 120 130 140 150 160 170 240 250 260 270 280 pF1KB7 PDYEV---------EAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYY- .. .: :.:.:. .::.::.::. ::.....:.. :.: :::::: NP_001 SGKDLTKRSSQTQNKASRKRQHEEPESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYL 180 190 200 210 220 230 290 300 pF1KB7 -KRMKPPE-EGTETSGDSQLLS : : :: : . :.. NP_001 VPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEGEDD 240 250 260 270 280 290 308 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 07:44:05 2016 done: Fri Nov 4 07:44:06 2016 Total Scan time: 7.980 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]