FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7437, 238 aa
1>>>pF1KB7437 238 - 238 aa - 238 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4114+/-0.00107; mu= 13.3504+/- 0.063
mean_var=67.3336+/-15.151, 0's: 0 Z-trim(101.9): 41 B-trim: 396 in 1/46
Lambda= 0.156300
statistics sampled from 6687 (6707) to 6687 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.552), E-opt: 0.2 (0.206), width: 16
Scan time: 2.170
The best scores are: opt bits E(32554)
CCDS41805.1 TMBIM4 gene_id:51643|Hs108|chr12 ( 238) 1497 346.8 7.5e-96
CCDS61187.1 TMBIM4 gene_id:51643|Hs108|chr12 ( 285) 1275 296.8 1e-80
CCDS81710.1 TMBIM4 gene_id:51643|Hs108|chr12 ( 162) 970 227.9 3.2e-60
CCDS34961.1 GRINA gene_id:2907|Hs108|chr8 ( 371) 398 99.1 4.4e-21
CCDS8791.1 FAIM2 gene_id:23017|Hs108|chr12 ( 316) 375 93.8 1.4e-19
CCDS2412.1 TMBIM1 gene_id:64114|Hs108|chr2 ( 311) 284 73.3 2.1e-13
>>CCDS41805.1 TMBIM4 gene_id:51643|Hs108|chr12 (238 aa)
initn: 1497 init1: 1497 opt: 1497 Z-score: 1834.3 bits: 346.8 E(32554): 7.5e-96
Smith-Waterman score: 1497; 100.0% identity (100.0% similar) in 238 aa overlap (1-238:1-238)
10 20 30 40 50 60
pF1KB7 MADPDPRYPRSSIEDDFNYGSSVASATVHIRMAFLRKVYSILSLQVLLTTVTSTVFLYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MADPDPRYPRSSIEDDFNYGSSVASATVHIRMAFLRKVYSILSLQVLLTTVTSTVFLYFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 SVRTFVHESPALILLFALGSLGLIFALILNRHKYPLNLYLLFGFTLLEALTVAVVVTFYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 SVRTFVHESPALILLFALGSLGLIFALILNRHKYPLNLYLLFGFTLLEALTVAVVVTFYD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VYIILQAFILTTTVFFGLTVYTLQSKKDFSKFGAGLFALLWILCLSGFLKFFFYSEIMEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 VYIILQAFILTTTVFFGLTVYTLQSKKDFSKFGAGLFALLWILCLSGFLKFFFYSEIMEL
130 140 150 160 170 180
190 200 210 220 230
pF1KB7 VLAAAGALLFCGFIIYDTHSLMHKLSPEEYVLAAISLYLDIINLFLHLLRFLEAVNKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 VLAAAGALLFCGFIIYDTHSLMHKLSPEEYVLAAISLYLDIINLFLHLLRFLEAVNKK
190 200 210 220 230
>>CCDS61187.1 TMBIM4 gene_id:51643|Hs108|chr12 (285 aa)
initn: 1275 init1: 1275 opt: 1275 Z-score: 1562.6 bits: 296.8 E(32554): 1e-80
Smith-Waterman score: 1279; 82.2% identity (82.6% similar) in 270 aa overlap (16-238:16-285)
10 20 30
pF1KB7 MADPDPRYPRSSIEDDFNYGSSVASATVHIRMA---------------------------
:::::::::::::::::.
CCDS61 MADPDPRYPRSSIEDDFNYGSSVASATVHIRMVLQRDCTFSKQYMRIPSAPSATLNIIRF
10 20 30 40 50 60
40 50 60 70
pF1KB7 --------------------FLRKVYSILSLQVLLTTVTSTVFLYFESVRTFVHESPALI
::::::::::::::::::::::::::::::::::::::::
CCDS61 FHLRQSGRSGMVNIFYKGPTFLRKVYSILSLQVLLTTVTSTVFLYFESVRTFVHESPALI
70 80 90 100 110 120
80 90 100 110 120 130
pF1KB7 LLFALGSLGLIFALILNRHKYPLNLYLLFGFTLLEALTVAVVVTFYDVYIILQAFILTTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 LLFALGSLGLIFALILNRHKYPLNLYLLFGFTLLEALTVAVVVTFYDVYIILQAFILTTT
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB7 VFFGLTVYTLQSKKDFSKFGAGLFALLWILCLSGFLKFFFYSEIMELVLAAAGALLFCGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 VFFGLTVYTLQSKKDFSKFGAGLFALLWILCLSGFLKFFFYSEIMELVLAAAGALLFCGF
190 200 210 220 230 240
200 210 220 230
pF1KB7 IIYDTHSLMHKLSPEEYVLAAISLYLDIINLFLHLLRFLEAVNKK
:::::::::::::::::::::::::::::::::::::::::::::
CCDS61 IIYDTHSLMHKLSPEEYVLAAISLYLDIINLFLHLLRFLEAVNKK
250 260 270 280
>>CCDS81710.1 TMBIM4 gene_id:51643|Hs108|chr12 (162 aa)
initn: 994 init1: 970 opt: 970 Z-score: 1194.6 bits: 227.9 E(32554): 3.2e-60
Smith-Waterman score: 970; 95.7% identity (99.4% similar) in 162 aa overlap (1-162:1-162)
10 20 30 40 50 60
pF1KB7 MADPDPRYPRSSIEDDFNYGSSVASATVHIRMAFLRKVYSILSLQVLLTTVTSTVFLYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MADPDPRYPRSSIEDDFNYGSSVASATVHIRMAFLRKVYSILSLQVLLTTVTSTVFLYFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 SVRTFVHESPALILLFALGSLGLIFALILNRHKYPLNLYLLFGFTLLEALTVAVVVTFYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SVRTFVHESPALILLFALGSLGLIFALILNRHKYPLNLYLLFGFTLLEALTVAVVVTFYD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VYIILQAFILTTTVFFGLTVYTLQSKKDFSKFGAGLFALLWILCLSGFLKFFFYSEIMEL
:::::::::::::::::::::::::::::::::::.. ....
CCDS81 VYIILQAFILTTTVFFGLTVYTLQSKKDFSKFGAGILEVFFL
130 140 150 160
190 200 210 220 230
pF1KB7 VLAAAGALLFCGFIIYDTHSLMHKLSPEEYVLAAISLYLDIINLFLHLLRFLEAVNKK
>>CCDS34961.1 GRINA gene_id:2907|Hs108|chr8 (371 aa)
initn: 418 init1: 211 opt: 398 Z-score: 492.1 bits: 99.1 E(32554): 4.4e-21
Smith-Waterman score: 398; 35.2% identity (69.5% similar) in 210 aa overlap (30-232:157-366)
10 20 30 40 50
pF1KB7 MADPDPRYPRSSIEDDFNYGSSVASATVHIRMAFLRKVYSILSLQVLLTTVTSTVFLYF
::.::.:::. .:.::. .: : .:: .
CCDS34 SPQHGNYQEEGPPSYYDNQDFPATNWDDKSIRQAFIRKVFLVLTLQLSVTLSTVSVFTFV
130 140 150 160 170 180
60 70 80 90 100 110
pF1KB7 ESVRTFVHESP-ALILLFALGSLGLIFALILN--RHKYPLNLYLLFGFTLLEALTVAVVV
:. ::.:. . . .:. ..:: . :.:.: :: : .: . :....
CCDS34 AEVKGFVRENVWTYYVSYAVFFISLIVLSCCGDFRRKHPWNLVALSVLTASLSYMVGMIA
190 200 210 220 230 240
120 130 140 150 160 170
pF1KB7 TFYDVYIILQAFILTTTVFFGLTVYTLQSKKDFSKFGAGLFALLWILCLSGFLKFFFYSE
.::.. ...: .::.: : ......:.. ::.. . :.. . .: . ..: .:. ..
CCDS34 SFYNTEAVIMAVGITTAVCFTVVIFSMQTRYDFTSCMGVLLVSMVVLFIFAILCIFIRNR
250 260 270 280 290 300
180 190 200 210 220 230
pF1KB7 IMELVLAAAGALLFCGFIIYDTHSLMHK----LSPEEYVLAAISLYLDIINLFLHLLRFL
:.:.: :. ::::: :. ::. :. . :::::::.::..:: ::::.::..: ..
CCDS34 ILEIVYASLGALLFTCFLAVDTQLLLGNKQLSLSPEEYVFAALNLYTDIINIFLYILTII
310 320 330 340 350 360
pF1KB7 EAVNKK
CCDS34 GRAKE
370
>>CCDS8791.1 FAIM2 gene_id:23017|Hs108|chr12 (316 aa)
initn: 342 init1: 135 opt: 375 Z-score: 465.1 bits: 93.8 E(32554): 1.4e-19
Smith-Waterman score: 375; 33.1% identity (62.9% similar) in 248 aa overlap (5-232:69-311)
10 20
pF1KB7 MADPDPRYPRSSIEDDFNYGSSVASATV-----H
:: :: .. : :. .: .
CCDS87 EEATSGEGMKAGAFPPAPTAVPLHPSWAYVDPS-SSSSYDNGFPTGDHELFTTFSWDDQK
40 50 60 70 80 90
30 40 50 60 70 80
pF1KB7 IRMAFLRKVYSILSLQVLLTTVTSTVFLYFESVRTFVHESPALILLFALGSLGLIFALIL
.: .:.::::.:: .:.:.: .. ..: . . :. .:. .:. . .: ...:: :
CCDS87 VRRVFVRKVYTILLIQLLVTLAVVALFTFCDPVKDYVQANPG----WYWASYAVFFATYL
100 110 120 130 140 150
90 100 110 120 130 140
pF1KB7 N-------RHKYPLNLYLLFGFTLLEALTVAVVVTFYDVYIILQAFILTTTVFFGLTVYT
. :...: :: :: ::: : .... ..:.. .: . .:. : ...::..
CCDS87 TLACCSGPRRHFPWNLILLTVFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTVFS
160 170 180 190 200 210
150 160 170 180 190
pF1KB7 LQSKKDFSKFGAGLFALLWILCLSGF----LKFFFYSEIMELVLAAAGALLFCGFIIYDT
.:.: ::.. . ::.:: : .::. : : : .. : :: :: .: :. ::
CCDS87 FQTKFDFTSCQGVLFVLLMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDT
220 230 240 250 260 270
200 210 220 230
pF1KB7 HSLM----HKLSPEEYVLAAISLYLDIINLFLHLLRFLEAVNKK
. :: :.::::::...:...::::: .: .:...
CCDS87 QLLMGNRRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE
280 290 300 310
>>CCDS2412.1 TMBIM1 gene_id:64114|Hs108|chr2 (311 aa)
initn: 233 init1: 120 opt: 284 Z-score: 354.3 bits: 73.3 E(32554): 2.1e-13
Smith-Waterman score: 362; 31.3% identity (68.7% similar) in 217 aa overlap (30-232:94-307)
10 20 30 40 50
pF1KB7 MADPDPRYPRSSIEDDFNYGSSVASATVHIRMAFLRKVYSILSLQVLLTTVTSTVFLYF
.: .:.::::::.:.:.:.:.. ..: .
CCDS24 PMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFV
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB7 ESVRTFVHESPALILLFALGSLGLIFALILN-----RHKYPLNLYLLFGFTLLEALTVAV
: : .::... :. .. .. .. ::: :...: :. :: ::. .. ...
CCDS24 EPVSAFVRRNVAVY--YVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGT
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB7 VVTFYDVYIILQAFILTTTVFFGLTVYTLQSKKDFSKFGAGLFALLWILCL-SGFLK---
. ..:.. .. :.:.:..: ...:.. .:.: ::.. .::: .: :. : .:..
CCDS24 ISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSC-TGLFCVLGIVLLVTGIVTSIV
190 200 210 220 230 240
180 190 200 210 220
pF1KB7 -FFFYSEIMELVLAAAGALLFCGFIIYDTHSLM----HKLSPEEYVLAAISLYLDIINLF
.: : .... :: ::. : :. :::. .. : .:::.:. .:...: ::: .:
CCDS24 LYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIF
250 260 270 280 290 300
230
pF1KB7 LHLLRFLEAVNKK
.:...
CCDS24 TFVLQLMGDRN
310
238 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 07:48:18 2016 done: Fri Nov 4 07:48:18 2016
Total Scan time: 2.170 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]