Result of FASTA (omim) for
pF1KB7441
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7441, 215 aa
1>>>pF1KB7441 215 - 215 aa - 215 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1518+/-0.000356; mu= 14.7659+/- 0.022
mean_var=68.2301+/-13.634, 0's: 0 Z-trim(113.5): 24 B-trim: 0 in 0/50
Lambda= 0.155269
statistics sampled from 22870 (22884) to 22870 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.268), width: 16
Scan time: 5.880
The best scores are: opt bits E(85289)
NP_715639 (OMIM: 605687) interleukin-19 isoform 1 ( 215) 1472 338.5 5.1e-93
NP_037503 (OMIM: 605687) interleukin-19 isoform 2 ( 177) 1184 273.9 1.2e-73
XP_011507752 (OMIM: 605687) PREDICTED: interleukin ( 207) 804 188.8 5.5e-48
XP_005273209 (OMIM: 605619) PREDICTED: interleukin ( 261) 462 112.3 7.7e-25
NP_061194 (OMIM: 605619) interleukin-20 precursor ( 176) 457 111.0 1.2e-24
NP_006841 (OMIM: 604136) interleukin-24 isoform 1 ( 206) 247 64.0 2e-10
NP_001172085 (OMIM: 604136) interleukin-24 isoform ( 207) 247 64.0 2e-10
XP_011507403 (OMIM: 604136) PREDICTED: interleukin ( 179) 242 62.9 3.9e-10
XP_016855610 (OMIM: 604136) PREDICTED: interleukin ( 179) 242 62.9 3.9e-10
>>NP_715639 (OMIM: 605687) interleukin-19 isoform 1 [Hom (215 aa)
initn: 1472 init1: 1472 opt: 1472 Z-score: 1790.9 bits: 338.5 E(85289): 5.1e-93
Smith-Waterman score: 1472; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215)
10 20 30 40 50 60
pF1KB7 MCTEGAFPHRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLGTILILCSVDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_715 MCTEGAFPHRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLGTILILCSVDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 HGLRRCLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_715 HGLRRCLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AFYVDRVFKDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_715 AFYVDRVFKDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHD
130 140 150 160 170 180
190 200 210
pF1KB7 NYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
:::::::::::::::::::::::::::::::::::
NP_715 NYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
190 200 210
>>NP_037503 (OMIM: 605687) interleukin-19 isoform 2 prec (177 aa)
initn: 1184 init1: 1184 opt: 1184 Z-score: 1443.5 bits: 273.9 E(85289): 1.2e-73
Smith-Waterman score: 1184; 100.0% identity (100.0% similar) in 177 aa overlap (39-215:1-177)
10 20 30 40 50 60
pF1KB7 HRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLGTILILCSVDNHGLRRCLI
::::::::::::::::::::::::::::::
NP_037 MKLQCVSLWLLGTILILCSVDNHGLRRCLI
10 20 30
70 80 90 100 110 120
pF1KB7 STDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLLAFYVDRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 STDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLLAFYVDRVF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 KDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHDNYDQLEVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 KDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHDNYDQLEVH
100 110 120 130 140 150
190 200 210
pF1KB7 AAAIKSLGELDVFLAWINKNHEVMFSA
:::::::::::::::::::::::::::
NP_037 AAAIKSLGELDVFLAWINKNHEVMFSA
160 170
>>XP_011507752 (OMIM: 605687) PREDICTED: interleukin-19 (207 aa)
initn: 804 init1: 804 opt: 804 Z-score: 982.5 bits: 188.8 E(85289): 5.5e-48
Smith-Waterman score: 804; 100.0% identity (100.0% similar) in 121 aa overlap (39-159:1-121)
10 20 30 40 50 60
pF1KB7 HRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLGTILILCSVDNHGLRRCLI
::::::::::::::::::::::::::::::
XP_011 MKLQCVSLWLLGTILILCSVDNHGLRRCLI
10 20 30
70 80 90 100 110 120
pF1KB7 STDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLLAFYVDRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLLAFYVDRVF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 KDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHDNYDQLEVH
:::::::::::::::::::::::::::::::
XP_011 KDHQEPNPKILRKISSIANSFLYMQKTLRQCVSHWVRIPASAPCLPKERPGSAGPHRPPD
100 110 120 130 140 150
190 200 210
pF1KB7 AAAIKSLGELDVFLAWINKNHEVMFSA
XP_011 MVLGVKGNSLRTSTGRTVENLSQWPLLPQGSLPADNSSDGLLLDNPPGVTNLCQHIP
160 170 180 190 200
>>XP_005273209 (OMIM: 605619) PREDICTED: interleukin-20 (261 aa)
initn: 436 init1: 403 opt: 462 Z-score: 567.0 bits: 112.3 E(85289): 7.7e-25
Smith-Waterman score: 462; 39.7% identity (71.2% similar) in 184 aa overlap (30-207:76-259)
10 20 30 40 50
pF1KB7 MCTEGAFPHRSACSLPLTHVHTHIHVCVPVLWGSVPRG-MKLQCVSLWLLGTILILCSV
.::. : :: . ... ::.. . : .
XP_005 GATTCATNSHSDSELRPEIFSSREAWQFFLLLWSPDFRPKMKASSLAFSLLSAAFYLLWT
50 60 70 80 90 100
60 70 80 90 100 110
pF1KB7 DNHGLRR-----CLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVC
. ::. :.:.:....:...:.::. ..:::: .. :: :.:: :: . :
XP_005 PSTGLKTLNLGSCVIATNLQEIRNGFSEIRGSVQAKDGNIDIRILRRTESLQDTKPANRC
110 120 130 140 150 160
120 130 140 150 160 170
pF1KB7 CVTKNLLAFYVDRVFKDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATN
:. ..:: .:.:::::..: :. ::::::.::::: ..: :: :. . ::: .:: .
XP_005 CLLRHLLRLYLDRVFKNYQTPDHYTLRKISSLANSFLTIKKDLRLCHAHMTCHCGEEAMK
170 180 190 200 210 220
180 190 200 210
pF1KB7 ATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
: .....:: .::..:.:::::..: :...
XP_005 KYSQILSHFEKLEPQAAVVKALGELDILLQWMEETE
230 240 250 260
>>NP_061194 (OMIM: 605619) interleukin-20 precursor [Hom (176 aa)
initn: 436 init1: 403 opt: 457 Z-score: 563.4 bits: 111.0 E(85289): 1.2e-24
Smith-Waterman score: 457; 40.2% identity (72.4% similar) in 174 aa overlap (39-207:1-174)
10 20 30 40 50 60
pF1KB7 HRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLGTILILCSVDNHGLRR---
:: . ... ::.. . : . . ::.
NP_061 MKASSLAFSLLSAAFYLLWTPSTGLKTLNL
10 20 30
70 80 90 100 110 120
pF1KB7 --CLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLLAFY
:.:.:....:...:.::. ..:::: .. :: :.:: :: . ::. ..:: .:
NP_061 GSCVIATNLQEIRNGFSEIRGSVQAKDGNIDIRILRRTESLQDTKPANRCCLLRHLLRLY
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 VDRVFKDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHDNYD
.:::::..: :. ::::::.::::: ..: :: :. . ::: .:: . : ....
NP_061 LDRVFKNYQTPDHYTLRKISSLANSFLTIKKDLRLCHAHMTCHCGEEAMKKYSQILSHFE
100 110 120 130 140 150
190 200 210
pF1KB7 QLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
.:: .::..:.:::::..: :...
NP_061 KLEPQAAVVKALGELDILLQWMEETE
160 170
>>NP_006841 (OMIM: 604136) interleukin-24 isoform 1 prec (206 aa)
initn: 214 init1: 127 opt: 247 Z-score: 308.2 bits: 64.0 E(85289): 2e-10
Smith-Waterman score: 247; 28.4% identity (65.8% similar) in 190 aa overlap (27-207:18-202)
10 20 30 40 50
pF1KB7 MCTEGAFPHRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLG-TILILCSVD
: :.: . ..: : : :: :.:. .:.
NP_006 MNFQQRLQSLWTLARPFCPPLL----ATASQMQMVVLPCLGFTLLLWSQVS
10 20 30 40
60 70 80 90 100 110
pF1KB7 N-HGLRR----CLISTDM-HHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVC
. .: . : .. . ... :.: .: ..::.:.. .. .:. :.:: .. . :
NP_006 GAQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQ-EVLQNVSDAESC
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 CVTKNLLAFYVDRVFKDHQEPNPKI--LRKISSIANSFLYMQKTLRQCQEQRQCHCRQEA
....:: ::. :::.... . .. :...:..::.:. . . :. ::... :. :
NP_006 YLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEMFSIRDSA
110 120 130 140 150 160
180 190 200 210
pF1KB7 TNATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
... . ::.:.:: :.:::.:..:.:..:
NP_006 HRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKFYKL
170 180 190 200
>>NP_001172085 (OMIM: 604136) interleukin-24 isoform 3 p (207 aa)
initn: 216 init1: 127 opt: 247 Z-score: 308.1 bits: 64.0 E(85289): 2e-10
Smith-Waterman score: 247; 28.4% identity (65.8% similar) in 190 aa overlap (27-207:19-203)
10 20 30 40 50
pF1KB7 MCTEGAFPHRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLG-TILILCSVD
: :.: . ..: : : :: :.:. .:.
NP_001 MNFQQRLQSLWTLASRPFCPPLL----ATASQMQMVVLPCLGFTLLLWSQVS
10 20 30 40
60 70 80 90 100 110
pF1KB7 N-HGLRR----CLISTDM-HHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVC
. .: . : .. . ... :.: .: ..::.:.. .. .:. :.:: .. . :
NP_001 GAQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQ-EVLQNVSDAESC
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 CVTKNLLAFYVDRVFKDHQEPNPKI--LRKISSIANSFLYMQKTLRQCQEQRQCHCRQEA
....:: ::. :::.... . .. :...:..::.:. . . :. ::... :. :
NP_001 YLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEMFSIRDSA
110 120 130 140 150 160
180 190 200 210
pF1KB7 TNATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
... . ::.:.:: :.:::.:..:.:..:
NP_001 HRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKFYKL
170 180 190 200
>>XP_011507403 (OMIM: 604136) PREDICTED: interleukin-24 (179 aa)
initn: 199 init1: 127 opt: 242 Z-score: 303.0 bits: 62.9 E(85289): 3.9e-10
Smith-Waterman score: 242; 30.8% identity (71.4% similar) in 133 aa overlap (77-207:44-175)
50 60 70 80 90 100
pF1KB7 WLLGTILILCSVDNHGLRRCLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQI
:.: .: ..::.:.. .. .:. :.::
XP_011 LLWSQVSGAQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQ-EVLQN
20 30 40 50 60 70
110 120 130 140 150 160
pF1KB7 IKPLDVCCVTKNLLAFYVDRVFKDHQEPNPKI--LRKISSIANSFLYMQKTLRQCQEQRQ
.. . : ....:: ::. :::.... . .. :...:..::.:. . . :. ::...
XP_011 VSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEM
80 90 100 110 120 130
170 180 190 200 210
pF1KB7 CHCRQEATNATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
:. : ... . ::.:.:: :.:::.:..:.:..:
XP_011 FSIRDSAHRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKFYKL
140 150 160 170
>>XP_016855610 (OMIM: 604136) PREDICTED: interleukin-24 (179 aa)
initn: 199 init1: 127 opt: 242 Z-score: 303.0 bits: 62.9 E(85289): 3.9e-10
Smith-Waterman score: 242; 30.8% identity (71.4% similar) in 133 aa overlap (77-207:44-175)
50 60 70 80 90 100
pF1KB7 WLLGTILILCSVDNHGLRRCLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQI
:.: .: ..::.:.. .. .:. :.::
XP_016 LLWSQVSGAQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQ-EVLQN
20 30 40 50 60 70
110 120 130 140 150 160
pF1KB7 IKPLDVCCVTKNLLAFYVDRVFKDHQEPNPKI--LRKISSIANSFLYMQKTLRQCQEQRQ
.. . : ....:: ::. :::.... . .. :...:..::.:. . . :. ::...
XP_016 VSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEM
80 90 100 110 120 130
170 180 190 200 210
pF1KB7 CHCRQEATNATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
:. : ... . ::.:.:: :.:::.:..:.:..:
XP_016 FSIRDSAHRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKFYKL
140 150 160 170
215 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 07:50:47 2016 done: Fri Nov 4 07:50:48 2016
Total Scan time: 5.880 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]