FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7447, 272 aa
1>>>pF1KB7447 272 - 272 aa - 272 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2343+/-0.000775; mu= 15.9783+/- 0.047
mean_var=77.2912+/-15.113, 0's: 0 Z-trim(109.4): 27 B-trim: 6 in 1/50
Lambda= 0.145885
statistics sampled from 10839 (10865) to 10839 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.334), width: 16
Scan time: 2.440
The best scores are: opt bits E(32554)
CCDS3806.1 MARCH1 gene_id:55016|Hs108|chr4 ( 272) 1891 407.0 7.1e-114
CCDS54814.1 MARCH1 gene_id:55016|Hs108|chr4 ( 289) 1642 354.7 4.4e-98
CCDS7213.1 MARCH8 gene_id:220972|Hs108|chr10 ( 291) 1190 259.5 1.9e-69
CCDS60519.1 MARCH8 gene_id:220972|Hs108|chr10 ( 573) 1129 246.9 2.4e-65
CCDS12202.1 MARCH2 gene_id:51257|Hs108|chr19 ( 246) 300 72.2 4.1e-13
CCDS4141.1 MARCH3 gene_id:115123|Hs108|chr5 ( 253) 296 71.3 7.6e-13
CCDS33376.1 MARCH4 gene_id:57574|Hs108|chr2 ( 410) 268 65.6 6.5e-11
>>CCDS3806.1 MARCH1 gene_id:55016|Hs108|chr4 (272 aa)
initn: 1891 init1: 1891 opt: 1891 Z-score: 2157.9 bits: 407.0 E(32554): 7.1e-114
Smith-Waterman score: 1891; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272)
10 20 30 40 50 60
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVCPSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS38 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVCPSTQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 DICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIMETKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS38 DICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIMETKLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 PLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS38 PLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 WTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFSCNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS38 WTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFSCNVN
190 200 210 220 230 240
250 260 270
pF1KB7 TDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
::::::::::::::::::::::::::::::::
CCDS38 TDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
250 260 270
>>CCDS54814.1 MARCH1 gene_id:55016|Hs108|chr4 (289 aa)
initn: 1640 init1: 1640 opt: 1642 Z-score: 1874.3 bits: 354.7 E(32554): 4.4e-98
Smith-Waterman score: 1642; 96.3% identity (98.8% similar) in 246 aa overlap (27-272:44-289)
10 20 30 40 50
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVC
..:. :. . .:::::::::::::::::::
CCDS54 RIPNNTRTPEISGDLADASQTSTLNEKSPGRSASRSSNISKASSPTTGTAPRSQSRLSVC
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB7 PSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIME
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB7 TKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVL
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB7 EWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFS
200 210 220 230 240 250
240 250 260 270
pF1KB7 CNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
::::::::::::::::::::::::::::::::::::
CCDS54 CNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
260 270 280
>>CCDS7213.1 MARCH8 gene_id:220972|Hs108|chr10 (291 aa)
initn: 1159 init1: 1159 opt: 1190 Z-score: 1360.2 bits: 259.5 E(32554): 1.9e-69
Smith-Waterman score: 1190; 67.8% identity (85.5% similar) in 255 aa overlap (23-272:41-291)
10 20 30 40
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP---RS
.........: .:.:: ...:: :
CCDS72 IPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNIS----KAGSPPSASAPAPVSS
20 30 40 50 60
50 60 70 80 90 100
pF1KB7 QSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELC
:: :. ::.::::::::::::.::::::::.:::.:.::::.::.::::::::::::::
CCDS72 FSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 KYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
::.:::::::::::::::::::.::::::.::::::::::::::::::::::::::::::
CCDS72 KYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 GNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAK
:. .:.::::::::::::::::::::.:::::::::::::.:::::::::.:::::.:.:
CCDS72 GQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSK
190 200 210 220 230 240
230 240 250 260 270
pF1KB7 K--LEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
: .::. . : . : . . .:... : :.. :
CCDS72 KNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
250 260 270 280 290
>>CCDS60519.1 MARCH8 gene_id:220972|Hs108|chr10 (573 aa)
initn: 1116 init1: 1116 opt: 1129 Z-score: 1286.8 bits: 246.9 E(32554): 2.4e-65
Smith-Waterman score: 1129; 70.1% identity (85.7% similar) in 231 aa overlap (46-272:343-573)
20 30 40 50 60 70
pF1KB7 KSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVCP--STQDICRICHCEGDEE
.: :.. . : .. :.:::::::::.:
CCDS60 FEDSTSAKLKSRVLRAPLCSTEKDSDLDCPSPFSEKLPPISPVSTSGDVCRICHCEGDDE
320 330 340 350 360 370
80 90 100 110 120 130
pF1KB7 SPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTS
:::::::.:::.:.::::.::.::::::::::::::::.:::::::::::::::::::.:
CCDS60 SPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSS
380 390 400 410 420 430
140 150 160 170 180 190
pF1KB7 ERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPFWTKLVVVAIGFTG
:::::.:::::::::::::::::::::::::::::::. .:.::::::::::::::::::
CCDS60 ERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVVVAIGFTG
440 450 460 470 480 490
200 210 220 230 240 250
pF1KB7 GLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKK--LEKNFSCNVNTDIKDAVVVPV
::.:::::::::::::.:::::::::.:::::.:.:: .::. . : . : . .
CCDS60 GLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENKHGYGICH
500 510 520 530 540 550
260 270
pF1KB7 PQTGANSLPSAEGGPPEVVSV
.:... : :.. :
CCDS60 SDTNSSCCTEPEDTGAEIIHV
560 570
>>CCDS12202.1 MARCH2 gene_id:51257|Hs108|chr19 (246 aa)
initn: 265 init1: 220 opt: 300 Z-score: 348.8 bits: 72.2 E(32554): 4.1e-13
Smith-Waterman score: 300; 30.7% identity (62.0% similar) in 163 aa overlap (57-218:58-216)
30 40 50 60 70 80
pF1KB7 QDAKLSNLFLQASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTL
:: .::::: :: . :..:: :::::
CCDS12 ATGLGPPQYVAQVTSRDGRLLSTVIRALDTPSDGPFCRICH-EGANGECLLSPCGCTGTL
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB7 RFVHQSCLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHV
::.:::..:..::.: ::::. .: .: . .:: .: : .:.: . :... .
CCDS12 GAVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPRPLTEWLKDPGPRTEKRTLCCDMVCFL
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB7 IAITCVVWSLYVLIDRTAEEIKQGND-NGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVY
. .. : .. . . .... .. ..: . : .. . .: :: . .:..:
CCDS12 FITPLAAISGWLCLRGAQDHLRLHSQLEAVGLIALTIALFTIYVLWT--LVSFRYHCQLY
150 160 170 180 190 200
210 220 230 240 250 260
pF1KB7 VQLWRRLKAYNRVIFVQNCPDTAKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGG
. ::. . :.
CCDS12 SE-WRKTNQKVRLKIREADSPEGPQHSPLAAGLLKKVAEETPV
210 220 230 240
>>CCDS4141.1 MARCH3 gene_id:115123|Hs108|chr5 (253 aa)
initn: 269 init1: 230 opt: 296 Z-score: 344.1 bits: 71.3 E(32554): 7.6e-13
Smith-Waterman score: 296; 30.2% identity (63.0% similar) in 192 aa overlap (62-248:70-253)
40 50 60 70 80 90
pF1KB7 SNLFLQASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQ
.::::: ::. . :..::.::::: .:.
CCDS41 YVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRICH-EGSSQEDLLSPCECTGTLGTIHR
40 50 60 70 80 90
100 110 120 130 140 150
pF1KB7 SCLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITC
:::..:..::.: ::::.. : .: : .:: .: . :.: .: ... ..
CCDS41 SCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPL
100 110 120 130 140 150
160 170 180 190 200 210
pF1KB7 VVWSLYVLIDRTAEEIKQGND-NGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWR
.. : .. . ...... .. ..: . . : .. . .: :: . .:..: . ::
CCDS41 ATISGWLCLRGAVDHLHFSSRLEAVGLIALTVALFTIYLFWT--LVSFRYHCRLYNE-WR
160 170 180 190 200 210
220 230 240 250 260
pF1KB7 RLKAYNRVIFVQ----NCPDTAKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGP
: . .:::.. : :.. .: : . :. :..::
CCDS41 RTN--QRVILLIPKSVNVPSNQPSLLGLHSVKRNS--KETVV
220 230 240 250
270
pF1KB7 PEVVSV
>>CCDS33376.1 MARCH4 gene_id:57574|Hs108|chr2 (410 aa)
initn: 195 init1: 169 opt: 268 Z-score: 309.4 bits: 65.6 E(32554): 6.5e-11
Smith-Waterman score: 268; 25.3% identity (51.8% similar) in 253 aa overlap (35-268:130-363)
10 20 30 40 50 60
pF1KB7 HVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVCPSTQD---
.:...: ....: :. : ..
CCDS33 EPPPVPPPPPLPPSSVEDDWGGPATEPPASLLSSASSDDFCKEKTEDRYSLGSSLDSGMR
100 110 120 130 140 150
70 80 90 100 110
pF1KB7 --ICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELC--KYDFIMET
.:::: .: :.. :..:::: :... .:: :: .::. :::: :: : .
CCDS33 TPLCRICF-QGPEQGELLSPCRCDGSVKCTHQPCLIKWISERGCWSCELCYYKYHVIAIS
160 170 180 190 200 210
120 130 140 150 160 170
pF1KB7 KLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLE
.:: .:. ...:. :. .. .. .. :. . : .. .. .:.
CCDS33 TKNPL-QWQAISLTVIEKVQVAAAILGSLFLIASISWLIWSTFSPSAR------------
220 230 240 250 260
180 190 200 210 220
pF1KB7 WPFWTKLVVVAIGFTGGLVFMYVQC---------KVYVQLWRRLKAYNRVIFVQNCPDTA
: : . :. : :: : : .:: ....: .: :. : : : .
CCDS33 WQRQDLLFQICYGMYG---FMDVVCIGLIIHEGPSVY-RIFKRWQAVNQQWKVLNY-DKT
270 280 290 300 310 320
230 240 250 260 270
pF1KB7 KKLEKNFS---CNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
: :: . . : :. . . .: . . . :. : :: .
CCDS33 KDLEDQKAGGRTNPRTSSSTQANIPSSEEETAGTPAPEQGPAQAAGHPSGPLSHHHCAYT
330 340 350 360 370 380
CCDS33 ILHILSHLRPHEQRSPPGSSRELVMRVTTV
390 400 410
272 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 07:55:01 2016 done: Fri Nov 4 07:55:02 2016
Total Scan time: 2.440 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]