FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7447, 272 aa
1>>>pF1KB7447 272 - 272 aa - 272 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0614+/-0.000325; mu= 16.7104+/- 0.020
mean_var=75.5878+/-14.710, 0's: 0 Z-trim(116.4): 64 B-trim: 18 in 1/50
Lambda= 0.147519
statistics sampled from 27488 (27556) to 27488 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.323), width: 16
Scan time: 6.900
The best scores are: opt bits E(85289)
NP_060393 (OMIM: 613331) E3 ubiquitin-protein liga ( 272) 1891 411.5 8.5e-115
XP_016863824 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 285) 1644 358.9 5.9e-99
XP_016863825 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 285) 1644 358.9 5.9e-99
XP_016863823 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 289) 1642 358.5 7.9e-99
NP_001159845 (OMIM: 613331) E3 ubiquitin-protein l ( 289) 1642 358.5 7.9e-99
XP_011530357 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 545) 1482 324.7 2.3e-88
NP_001002266 (OMIM: 613335) E3 ubiquitin-protein l ( 291) 1190 262.3 7.3e-70
NP_659458 (OMIM: 613335) E3 ubiquitin-protein liga ( 291) 1190 262.3 7.3e-70
XP_016871383 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 291) 1190 262.3 7.3e-70
XP_011537797 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 291) 1190 262.3 7.3e-70
XP_011537796 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1129 249.6 9.7e-66
XP_011537795 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1129 249.6 9.7e-66
XP_011537794 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1129 249.6 9.7e-66
XP_006717767 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1129 249.6 9.7e-66
XP_005271861 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1129 249.6 9.7e-66
NP_001269795 (OMIM: 613335) E3 ubiquitin-protein l ( 573) 1129 249.6 9.7e-66
NP_001005415 (OMIM: 613332) E3 ubiquitin-protein l ( 246) 300 72.9 6.7e-13
NP_057580 (OMIM: 613332) E3 ubiquitin-protein liga ( 246) 300 72.9 6.7e-13
XP_016882342 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 246) 300 72.9 6.7e-13
NP_848545 (OMIM: 613333) E3 ubiquitin-protein liga ( 253) 296 72.0 1.2e-12
XP_011526349 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 256) 288 70.3 4e-12
XP_011526348 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 256) 288 70.3 4e-12
NP_065865 (OMIM: 608208) E3 ubiquitin-protein liga ( 410) 268 66.2 1.1e-10
NP_001096032 (OMIM: 613338) E3 ubiquitin-protein l ( 402) 263 65.2 2.3e-10
XP_016864504 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 154) 258 63.7 2.3e-10
XP_011541431 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 280) 261 64.6 2.3e-10
XP_011541433 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 280) 261 64.6 2.3e-10
XP_011541432 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 280) 261 64.6 2.3e-10
XP_016864433 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 460) 258 64.1 5.2e-10
XP_011512238 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 637) 258 64.3 6.7e-10
XP_011512236 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 791) 258 64.3 7.8e-10
NP_005876 (OMIM: 613297) E3 ubiquitin-protein liga ( 910) 258 64.4 8.7e-10
XP_006722826 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 176) 249 61.9 9.6e-10
NP_001005416 (OMIM: 613332) E3 ubiquitin-protein l ( 176) 249 61.9 9.6e-10
NP_001257589 (OMIM: 613297) E3 ubiquitin-protein l ( 862) 255 63.7 1.3e-09
NP_612405 (OMIM: 613336) E3 ubiquitin-protein liga ( 346) 247 61.7 2.1e-09
XP_005257163 (OMIM: 613337) PREDICTED: probable E3 ( 752) 201 52.2 3.4e-06
XP_005257160 (OMIM: 613337) PREDICTED: probable E3 ( 799) 201 52.2 3.5e-06
NP_001275709 (OMIM: 613337) probable E3 ubiquitin- ( 799) 201 52.2 3.5e-06
XP_011522739 (OMIM: 613337) PREDICTED: probable E3 ( 807) 201 52.2 3.6e-06
NP_689811 (OMIM: 613337) probable E3 ubiquitin-pro ( 808) 201 52.2 3.6e-06
NP_001094345 (OMIM: 613337) probable E3 ubiquitin- ( 808) 201 52.2 3.6e-06
XP_005257159 (OMIM: 613337) PREDICTED: probable E3 ( 824) 201 52.2 3.6e-06
XP_011522738 (OMIM: 613337) PREDICTED: probable E3 ( 825) 201 52.2 3.6e-06
XP_005257157 (OMIM: 613337) PREDICTED: probable E3 ( 825) 201 52.2 3.6e-06
NP_001275708 (OMIM: 613337) probable E3 ubiquitin- ( 846) 201 52.2 3.7e-06
XP_005257155 (OMIM: 613337) PREDICTED: probable E3 ( 862) 201 52.2 3.8e-06
XP_011522737 (OMIM: 613337) PREDICTED: probable E3 ( 862) 201 52.2 3.8e-06
XP_005257153 (OMIM: 613337) PREDICTED: probable E3 ( 863) 201 52.2 3.8e-06
XP_005257154 (OMIM: 613337) PREDICTED: probable E3 ( 863) 201 52.2 3.8e-06
>>NP_060393 (OMIM: 613331) E3 ubiquitin-protein ligase M (272 aa)
initn: 1891 init1: 1891 opt: 1891 Z-score: 2182.0 bits: 411.5 E(85289): 8.5e-115
Smith-Waterman score: 1891; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272)
10 20 30 40 50 60
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVCPSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVCPSTQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 DICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIMETKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIMETKLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 PLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 WTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFSCNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 WTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFSCNVN
190 200 210 220 230 240
250 260 270
pF1KB7 TDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
::::::::::::::::::::::::::::::::
NP_060 TDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
250 260 270
>>XP_016863824 (OMIM: 613331) PREDICTED: E3 ubiquitin-pr (285 aa)
initn: 1640 init1: 1640 opt: 1644 Z-score: 1897.6 bits: 358.9 E(85289): 5.9e-99
Smith-Waterman score: 1644; 91.6% identity (96.2% similar) in 261 aa overlap (12-272:25-285)
10 20 30 40
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP
: :.... . ...:. :. . .::::::::::
XP_016 MPLHQISVIPARETASNGRNSMGRNKEKNKEVENEKSPGRSASRSSNISKASSPTTGTAP
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 RSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 LCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 KQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDT
190 200 210 220 230 240
230 240 250 260 270
pF1KB7 AKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
250 260 270 280
>>XP_016863825 (OMIM: 613331) PREDICTED: E3 ubiquitin-pr (285 aa)
initn: 1640 init1: 1640 opt: 1644 Z-score: 1897.6 bits: 358.9 E(85289): 5.9e-99
Smith-Waterman score: 1644; 91.6% identity (96.2% similar) in 261 aa overlap (12-272:25-285)
10 20 30 40
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP
: :.... . ...:. :. . .::::::::::
XP_016 MPLHQISVIPARETASNGRNSMGRNKEKNKEVENEKSPGRSASRSSNISKASSPTTGTAP
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 RSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 LCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 KQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDT
190 200 210 220 230 240
230 240 250 260 270
pF1KB7 AKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
250 260 270 280
>>XP_016863823 (OMIM: 613331) PREDICTED: E3 ubiquitin-pr (289 aa)
initn: 1640 init1: 1640 opt: 1642 Z-score: 1895.2 bits: 358.5 E(85289): 7.9e-99
Smith-Waterman score: 1642; 96.3% identity (98.8% similar) in 246 aa overlap (27-272:44-289)
10 20 30 40 50
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVC
..:. :. . .:::::::::::::::::::
XP_016 RIPNNTRTPEISGDLADASQTSTLNEKSPGRSASRSSNISKASSPTTGTAPRSQSRLSVC
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB7 PSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIME
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB7 TKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVL
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB7 EWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFS
200 210 220 230 240 250
240 250 260 270
pF1KB7 CNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
::::::::::::::::::::::::::::::::::::
XP_016 CNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
260 270 280
>>NP_001159845 (OMIM: 613331) E3 ubiquitin-protein ligas (289 aa)
initn: 1640 init1: 1640 opt: 1642 Z-score: 1895.2 bits: 358.5 E(85289): 7.9e-99
Smith-Waterman score: 1642; 96.3% identity (98.8% similar) in 246 aa overlap (27-272:44-289)
10 20 30 40 50
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVC
..:. :. . .:::::::::::::::::::
NP_001 RIPNNTRTPEISGDLADASQTSTLNEKSPGRSASRSSNISKASSPTTGTAPRSQSRLSVC
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB7 PSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIME
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB7 TKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVL
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB7 EWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEKNFS
200 210 220 230 240 250
240 250 260 270
pF1KB7 CNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
::::::::::::::::::::::::::::::::::::
NP_001 CNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
260 270 280
>>XP_011530357 (OMIM: 613331) PREDICTED: E3 ubiquitin-pr (545 aa)
initn: 1482 init1: 1482 opt: 1482 Z-score: 1707.5 bits: 324.7 E(85289): 2.3e-88
Smith-Waterman score: 1482; 99.1% identity (100.0% similar) in 212 aa overlap (61-272:334-545)
40 50 60 70 80 90
pF1KB7 LSNLFLQASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVH
..::::::::::::::::::::::::::::
XP_011 GSKDMNDAGLQVNNPVQKPPATYDDGSDNLEVCRICHCEGDEESPLITPCRCTGTLRFVH
310 320 330 340 350 360
100 110 120 130 140 150
pF1KB7 QSCLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSCLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAIT
370 380 390 400 410 420
160 170 180 190 200 210
pF1KB7 CVVWSLYVLIDRTAEEIKQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVVWSLYVLIDRTAEEIKQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWR
430 440 450 460 470 480
220 230 240 250 260 270
pF1KB7 RLKAYNRVIFVQNCPDTAKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLKAYNRVIFVQNCPDTAKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVV
490 500 510 520 530 540
pF1KB7 SV
::
XP_011 SV
>--
initn: 220 init1: 184 opt: 212 Z-score: 246.8 bits: 54.4 E(85289): 5.3e-07
Smith-Waterman score: 212; 37.4% identity (62.6% similar) in 115 aa overlap (27-139:44-156)
10 20 30 40 50
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAPRSQSRLSVC
..:. :. . .:::::::::::::::::::
XP_011 RIPNNTRTPEISGDLADASQTSTLNEKSPGRSASRSSNISKASSPTTGTAPRSQSRLSVC
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB7 PSTQDICR--ICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFI
:::::::: : : ..: :: . : ..: .. :. : .:.
XP_011 PSTQDICRSAILHDMSEESFEYCTPVMVLSPAR--KESGKKSVIQRPRRRRKASERYEHA
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB7 METKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNG
: ... .. .::... . :...
XP_011 AEEQIRGRKNDFHLQISSPRWRELYTDSSDSSSTDESHWIQAKRRAQVKFRLSRRRRRNN
140 150 160 170 180 190
>>NP_001002266 (OMIM: 613335) E3 ubiquitin-protein ligas (291 aa)
initn: 1159 init1: 1159 opt: 1190 Z-score: 1375.3 bits: 262.3 E(85289): 7.3e-70
Smith-Waterman score: 1190; 67.8% identity (85.5% similar) in 255 aa overlap (23-272:41-291)
10 20 30 40
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP---RS
.........: .:.:: ...:: :
NP_001 IPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNIS----KAGSPPSASAPAPVSS
20 30 40 50 60
50 60 70 80 90 100
pF1KB7 QSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELC
:: :. ::.::::::::::::.::::::::.:::.:.::::.::.::::::::::::::
NP_001 FSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 KYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
::.:::::::::::::::::::.::::::.::::::::::::::::::::::::::::::
NP_001 KYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 GNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAK
:. .:.::::::::::::::::::::.:::::::::::::.:::::::::.:::::.:.:
NP_001 GQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSK
190 200 210 220 230 240
230 240 250 260 270
pF1KB7 K--LEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
: .::. . : . : . . .:... : :.. :
NP_001 KNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
250 260 270 280 290
>>NP_659458 (OMIM: 613335) E3 ubiquitin-protein ligase M (291 aa)
initn: 1159 init1: 1159 opt: 1190 Z-score: 1375.3 bits: 262.3 E(85289): 7.3e-70
Smith-Waterman score: 1190; 67.8% identity (85.5% similar) in 255 aa overlap (23-272:41-291)
10 20 30 40
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP---RS
.........: .:.:: ...:: :
NP_659 IPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNIS----KAGSPPSASAPAPVSS
20 30 40 50 60
50 60 70 80 90 100
pF1KB7 QSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELC
:: :. ::.::::::::::::.::::::::.:::.:.::::.::.::::::::::::::
NP_659 FSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 KYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
::.:::::::::::::::::::.::::::.::::::::::::::::::::::::::::::
NP_659 KYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 GNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAK
:. .:.::::::::::::::::::::.:::::::::::::.:::::::::.:::::.:.:
NP_659 GQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSK
190 200 210 220 230 240
230 240 250 260 270
pF1KB7 K--LEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
: .::. . : . : . . .:... : :.. :
NP_659 KNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
250 260 270 280 290
>>XP_016871383 (OMIM: 613335) PREDICTED: E3 ubiquitin-pr (291 aa)
initn: 1159 init1: 1159 opt: 1190 Z-score: 1375.3 bits: 262.3 E(85289): 7.3e-70
Smith-Waterman score: 1190; 67.8% identity (85.5% similar) in 255 aa overlap (23-272:41-291)
10 20 30 40
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP---RS
.........: .:.:: ...:: :
XP_016 IPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNIS----KAGSPPSASAPAPVSS
20 30 40 50 60
50 60 70 80 90 100
pF1KB7 QSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELC
:: :. ::.::::::::::::.::::::::.:::.:.::::.::.::::::::::::::
XP_016 FSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 KYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
::.:::::::::::::::::::.::::::.::::::::::::::::::::::::::::::
XP_016 KYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 GNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAK
:. .:.::::::::::::::::::::.:::::::::::::.:::::::::.:::::.:.:
XP_016 GQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSK
190 200 210 220 230 240
230 240 250 260 270
pF1KB7 K--LEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
: .::. . : . : . . .:... : :.. :
XP_016 KNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
250 260 270 280 290
>>XP_011537797 (OMIM: 613335) PREDICTED: E3 ubiquitin-pr (291 aa)
initn: 1159 init1: 1159 opt: 1190 Z-score: 1375.3 bits: 262.3 E(85289): 7.3e-70
Smith-Waterman score: 1190; 67.8% identity (85.5% similar) in 255 aa overlap (23-272:41-291)
10 20 30 40
pF1KB7 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP---RS
.........: .:.:: ...:: :
XP_011 IPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNIS----KAGSPPSASAPAPVSS
20 30 40 50 60
50 60 70 80 90 100
pF1KB7 QSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELC
:: :. ::.::::::::::::.::::::::.:::.:.::::.::.::::::::::::::
XP_011 FSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 KYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
::.:::::::::::::::::::.::::::.::::::::::::::::::::::::::::::
XP_011 KYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 GNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAK
:. .:.::::::::::::::::::::.:::::::::::::.:::::::::.:::::.:.:
XP_011 GQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSK
190 200 210 220 230 240
230 240 250 260 270
pF1KB7 K--LEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
: .::. . : . : . . .:... : :.. :
XP_011 KNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
250 260 270 280 290
272 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 07:55:02 2016 done: Fri Nov 4 07:55:03 2016
Total Scan time: 6.900 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]