FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7449, 188 aa 1>>>pF1KB7449 188 - 188 aa - 188 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7291+/-0.000302; mu= 13.1923+/- 0.019 mean_var=103.7399+/-20.863, 0's: 0 Z-trim(119.9): 28 B-trim: 0 in 0/55 Lambda= 0.125922 statistics sampled from 34521 (34549) to 34521 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.405), width: 16 Scan time: 6.110 The best scores are: opt bits E(85289) NP_005626 (OMIM: 300813,312820) protein SSX1 [Homo ( 188) 1019 194.5 8.4e-50 NP_001265620 (OMIM: 300813,312820) protein SSX1 [H ( 188) 1019 194.5 8.4e-50 NP_783629 (OMIM: 300192,300813) protein SSX2 isofo ( 188) 1015 193.8 1.4e-49 NP_775494 (OMIM: 300542) protein SSX7 [Homo sapien ( 188) 1005 192.0 4.9e-49 NP_066294 (OMIM: 300325) protein SSX3 [Homo sapien ( 188) 985 188.3 6.1e-48 NP_005627 (OMIM: 300326) protein SSX4 isoform a [H ( 188) 967 185.1 5.9e-47 XP_016885248 (OMIM: 300326) PREDICTED: protein SSX ( 188) 967 185.1 5.9e-47 NP_783729 (OMIM: 300327) protein SSX5 isoform b [H ( 188) 961 184.0 1.2e-46 XP_011542251 (OMIM: 300327) PREDICTED: protein SSX ( 188) 961 184.0 1.2e-46 XP_016885247 (OMIM: 300327) PREDICTED: protein SSX ( 188) 961 184.0 1.2e-46 NP_066295 (OMIM: 300327) protein SSX5 isoform a [H ( 229) 878 169.0 5e-42 NP_001265626 (OMIM: 300192,300813) protein SSX2 is ( 214) 806 155.9 4.1e-38 NP_003138 (OMIM: 300192,300813) protein SSX2 isofo ( 223) 806 155.9 4.2e-38 XP_016884919 (OMIM: 300542) PREDICTED: protein SSX ( 223) 789 152.8 3.6e-37 XP_011542187 (OMIM: 300325) PREDICTED: protein SSX ( 170) 771 149.4 2.8e-36 NP_783856 (OMIM: 300326) protein SSX4 isoform b [H ( 153) 529 105.4 4.5e-23 XP_016884920 (OMIM: 300542) PREDICTED: protein SSX ( 129) 526 104.8 5.8e-23 NP_001297143 (OMIM: 609760) histone-lysine N-methy ( 894) 190 44.5 0.00056 NP_064612 (OMIM: 609760) histone-lysine N-methyltr ( 894) 190 44.5 0.00056 XP_011521131 (OMIM: 609759) PREDICTED: probable hi ( 377) 172 40.9 0.0029 XP_005256331 (OMIM: 609759) PREDICTED: probable hi ( 492) 172 41.0 0.0035 NP_001091643 (OMIM: 609759) probable histone-lysin ( 492) 172 41.0 0.0035 XP_011521133 (OMIM: 609759) PREDICTED: probable hi ( 172) 160 38.4 0.0074 >>NP_005626 (OMIM: 300813,312820) protein SSX1 [Homo sap (188 aa) initn: 1051 init1: 1019 opt: 1019 Z-score: 1015.1 bits: 194.5 E(85289): 8.4e-50 Smith-Waterman score: 1019; 81.4% identity (92.6% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFAKRPRDDAKASEKRSKAFDDIAKYFSKEEWEKMKFSEKISCVHMKRKYEAMTK :::::.::::::::::::::::::::::: ::::.::.:::.::::: :.:::.:.:::: NP_005 MNGDDTFAKRPRDDAKASEKRSKAFDDIATYFSKKEWKKMKYSEKISYVYMKRNYKAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFNVTLSLFMRNKRATDSQRNDSDNDRNRGNEVERPQMTFGRLQRIIPKIMPEKPAEEG :::.::: :: ::.::: : :: :::.:: .::.::::::::.::::::::.::::. NP_005 LGFKVTLPPFMCNKQATDFQGNDFDNDHNRRIQVEHPQMTFGRLHRIIPKIMPKKPAEDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SDSKGVPEASGPQNDGKKLCPPGKASSSEKIHERSGPKRGKHAWTHRLRERKQLVIYEEI .::::: ::::::::::.: :::::. ::::..::::::::::::::::::::::::::: NP_005 NDSKGVSEASGPQNDGKQLHPPGKANISEKINKRSGPKRGKHAWTHRLRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDK :::::::. NP_005 SDPEEDDE >>NP_001265620 (OMIM: 300813,312820) protein SSX1 [Homo (188 aa) initn: 1051 init1: 1019 opt: 1019 Z-score: 1015.1 bits: 194.5 E(85289): 8.4e-50 Smith-Waterman score: 1019; 81.4% identity (92.6% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFAKRPRDDAKASEKRSKAFDDIAKYFSKEEWEKMKFSEKISCVHMKRKYEAMTK :::::.::::::::::::::::::::::: ::::.::.:::.::::: :.:::.:.:::: NP_001 MNGDDTFAKRPRDDAKASEKRSKAFDDIATYFSKKEWKKMKYSEKISYVYMKRNYKAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFNVTLSLFMRNKRATDSQRNDSDNDRNRGNEVERPQMTFGRLQRIIPKIMPEKPAEEG :::.::: :: ::.::: : :: :::.:: .::.::::::::.::::::::.::::. NP_001 LGFKVTLPPFMCNKQATDFQGNDFDNDHNRRIQVEHPQMTFGRLHRIIPKIMPKKPAEDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SDSKGVPEASGPQNDGKKLCPPGKASSSEKIHERSGPKRGKHAWTHRLRERKQLVIYEEI .::::: ::::::::::.: :::::. ::::..::::::::::::::::::::::::::: NP_001 NDSKGVSEASGPQNDGKQLHPPGKANISEKINKRSGPKRGKHAWTHRLRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDK :::::::. NP_001 SDPEEDDE >>NP_783629 (OMIM: 300192,300813) protein SSX2 isoform b (188 aa) initn: 1084 init1: 1015 opt: 1015 Z-score: 1011.2 bits: 193.8 E(85289): 1.4e-49 Smith-Waterman score: 1015; 80.9% identity (88.8% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFAKRPRDDAKASEKRSKAFDDIAKYFSKEEWEKMKFSEKISCVHMKRKYEAMTK ::::::::.:: :. :: .::::::::::::::::::: :::: :.:::::::::: NP_783 MNGDDAFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKASEKIFYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFNVTLSLFMRNKRATDSQRNDSDNDRNRGNEVERPQMTFGRLQRIIPKIMPEKPAEEG :::..:: :: :::: : : :: ::: ::::.:::::::::::: : :::::.:::::: NP_783 LGFKATLPPFMCNKRAEDFQGNDLDNDPNRGNQVERPQMTFGRLQGISPKIMPKKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SDSKGVPEASGPQNDGKKLCPPGKASSSEKIHERSGPKRGKHAWTHRLRERKQLVIYEEI .::. ::::::::::::.:::::: ..:::::::::::::.::::::::::::::::::: NP_783 NDSEEVPEASGPQNDGKELCPPGKPTTSEKIHERSGPKRGEHAWTHRLRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDK :::::::. NP_783 SDPEEDDE >>NP_775494 (OMIM: 300542) protein SSX7 [Homo sapiens] (188 aa) initn: 1037 init1: 1005 opt: 1005 Z-score: 1001.4 bits: 192.0 E(85289): 4.9e-49 Smith-Waterman score: 1005; 79.8% identity (89.9% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFAKRPRDDAKASEKRSKAFDDIAKYFSKEEWEKMKFSEKISCVHMKRKYEAMTK ::::::::.::: :. :: .:.::::::::::.:::::: :::: :.:::::::::: NP_775 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFNVTLSLFMRNKRATDSQRNDSDNDRNRGNEVERPQMTFGRLQRIIPKIMPEKPAEEG :::..:: ::.: ::: : :: :::::.::.:::::::: :::::.:::::.:::::: NP_775 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SDSKGVPEASGPQNDGKKLCPPGKASSSEKIHERSGPKRGKHAWTHRLRERKQLVIYEEI .:::::::::: :::::.:::::: :.::::.. :::::::::::::::::::::::::: NP_775 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSGPKRGKHAWTHRLRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDK :::::::. NP_775 SDPEEDDE >>NP_066294 (OMIM: 300325) protein SSX3 [Homo sapiens] (188 aa) initn: 985 init1: 985 opt: 985 Z-score: 981.7 bits: 188.3 E(85289): 6.1e-48 Smith-Waterman score: 985; 78.2% identity (88.3% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFAKRPRDDAKASEKRSKAFDDIAKYFSKEEWEKMKFSEKISCVHMKRKYEAMTK :::::.::.:: :. :: .::::::::::::::::::: :::: :.:::::::::: NP_066 MNGDDTFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKVSEKIVYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFNVTLSLFMRNKRATDSQRNDSDNDRNRGNEVERPQMTFGRLQRIIPKIMPEKPAEEG :::.. : ::::::.:: : :: ::: ::::.:.:::::::::: :.:::::.:::::: NP_066 LGFKAILPSFMRNKRVTDFQGNDFDNDPNRGNQVQRPQMTFGRLQGIFPKIMPKKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SDSKGVPEASGPQNDGKKLCPPGKASSSEKIHERSGPKRGKHAWTHRLRERKQLVIYEEI . :: ::::::::::::.:::::: ..::::. ::::::.::::::::::::::::::: NP_066 NVSKEVPEASGPQNDGKQLCPPGKPTTSEKINMISGPKRGEHAWTHRLRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDK :::::::. NP_066 SDPEEDDE >>NP_005627 (OMIM: 300326) protein SSX4 isoform a [Homo (188 aa) initn: 1002 init1: 967 opt: 967 Z-score: 964.0 bits: 185.1 E(85289): 5.9e-47 Smith-Waterman score: 967; 76.6% identity (88.3% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFAKRPRDDAKASEKRSKAFDDIAKYFSKEEWEKMKFSEKISCVHMKRKYEAMTK ::::::::.::::::. ::: ::::::::::::.:::::: :::: :.:: .::.::: NP_005 MNGDDAFARRPRDDAQISEKLRKAFDDIAKYFSKKEWEKMKSSEKIVYVYMKLNYEVMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFNVTLSLFMRNKRATDSQRNDSDNDRNRGNEVERPQMTFGRLQRIIPKIMPEKPAEEG :::.::: :::.:::.: . :: ::::. :.::::::::: ::::.:::::.::::: NP_005 LGFKVTLPPFMRSKRAADFHGNDFGNDRNHRNQVERPQMTFGSLQRIFPKIMPKKPAEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SDSKGVPEASGPQNDGKKLCPPGKASSSEKIHERSGPKRGKHAWTHRLRERKQLVIYEEI . : ::::::::::::.:::::. :. :::.. :::::::::::::::::::::.:::: NP_005 NGLKEVPEASGPQNDGKQLCPPGNPSTLEKINKTSGPKRGKHAWTHRLRERKQLVVYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDK :::::::. NP_005 SDPEEDDE >>XP_016885248 (OMIM: 300326) PREDICTED: protein SSX4 is (188 aa) initn: 1002 init1: 967 opt: 967 Z-score: 964.0 bits: 185.1 E(85289): 5.9e-47 Smith-Waterman score: 967; 76.6% identity (88.3% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFAKRPRDDAKASEKRSKAFDDIAKYFSKEEWEKMKFSEKISCVHMKRKYEAMTK ::::::::.::::::. ::: ::::::::::::.:::::: :::: :.:: .::.::: XP_016 MNGDDAFARRPRDDAQISEKLRKAFDDIAKYFSKKEWEKMKSSEKIVYVYMKLNYEVMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFNVTLSLFMRNKRATDSQRNDSDNDRNRGNEVERPQMTFGRLQRIIPKIMPEKPAEEG :::.::: :::.:::.: . :: ::::. :.::::::::: ::::.:::::.::::: XP_016 LGFKVTLPPFMRSKRAADFHGNDFGNDRNHRNQVERPQMTFGSLQRIFPKIMPKKPAEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SDSKGVPEASGPQNDGKKLCPPGKASSSEKIHERSGPKRGKHAWTHRLRERKQLVIYEEI . : ::::::::::::.:::::. :. :::.. :::::::::::::::::::::.:::: XP_016 NGLKEVPEASGPQNDGKQLCPPGNPSTLEKINKTSGPKRGKHAWTHRLRERKQLVVYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDK :::::::. XP_016 SDPEEDDE >>NP_783729 (OMIM: 300327) protein SSX5 isoform b [Homo (188 aa) initn: 1020 init1: 961 opt: 961 Z-score: 958.2 bits: 184.0 E(85289): 1.2e-46 Smith-Waterman score: 961; 75.5% identity (89.4% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFAKRPRDDAKASEKRSKAFDDIAKYFSKEEWEKMKFSEKISCVHMKRKYEAMTK :::::::..::: .. :: .:::::::::::..:::::: :::: :.:::::::::: NP_783 MNGDDAFVRRPRVGSQIPEKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFNVTLSLFMRNKRATDSQRNDSDNDRNRGNEVERPQMTFGRLQRIIPKIMPEKPAEEG :::..:: ::::::..: : :: ::: ::::.::.::::::::: :.::: :::::::: NP_783 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SDSKGVPEASGPQNDGKKLCPPGKASSSEKIHERSGPKRGKHAWTHRLRERKQLVIYEEI .:::::::::::::.::.: : :: ..:::... :::::::::::::.:::::::::::: NP_783 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDK :::.:::. NP_783 SDPQEDDE >>XP_011542251 (OMIM: 300327) PREDICTED: protein SSX5 is (188 aa) initn: 1020 init1: 961 opt: 961 Z-score: 958.2 bits: 184.0 E(85289): 1.2e-46 Smith-Waterman score: 961; 75.5% identity (89.4% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFAKRPRDDAKASEKRSKAFDDIAKYFSKEEWEKMKFSEKISCVHMKRKYEAMTK :::::::..::: .. :: .:::::::::::..:::::: :::: :.:::::::::: XP_011 MNGDDAFVRRPRVGSQIPEKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFNVTLSLFMRNKRATDSQRNDSDNDRNRGNEVERPQMTFGRLQRIIPKIMPEKPAEEG :::..:: ::::::..: : :: ::: ::::.::.::::::::: :.::: :::::::: XP_011 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SDSKGVPEASGPQNDGKKLCPPGKASSSEKIHERSGPKRGKHAWTHRLRERKQLVIYEEI .:::::::::::::.::.: : :: ..:::... :::::::::::::.:::::::::::: XP_011 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDK :::.:::. XP_011 SDPQEDDE >>XP_016885247 (OMIM: 300327) PREDICTED: protein SSX5 is (188 aa) initn: 1020 init1: 961 opt: 961 Z-score: 958.2 bits: 184.0 E(85289): 1.2e-46 Smith-Waterman score: 961; 75.5% identity (89.4% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MNGDDAFAKRPRDDAKASEKRSKAFDDIAKYFSKEEWEKMKFSEKISCVHMKRKYEAMTK :::::::..::: .. :: .:::::::::::..:::::: :::: :.:::::::::: XP_016 MNGDDAFVRRPRVGSQIPEKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LGFNVTLSLFMRNKRATDSQRNDSDNDRNRGNEVERPQMTFGRLQRIIPKIMPEKPAEEG :::..:: ::::::..: : :: ::: ::::.::.::::::::: :.::: :::::::: XP_016 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SDSKGVPEASGPQNDGKKLCPPGKASSSEKIHERSGPKRGKHAWTHRLRERKQLVIYEEI .:::::::::::::.::.: : :: ..:::... :::::::::::::.:::::::::::: XP_016 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI 130 140 150 160 170 180 pF1KB7 SDPEEDDK :::.:::. XP_016 SDPQEDDE 188 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 07:56:09 2016 done: Fri Nov 4 07:56:10 2016 Total Scan time: 6.110 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]