FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7506, 240 aa 1>>>pF1KB7506 240 - 240 aa - 240 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3394+/-0.000733; mu= 8.1564+/- 0.045 mean_var=191.7183+/-39.766, 0's: 0 Z-trim(116.2): 171 B-trim: 849 in 1/53 Lambda= 0.092628 statistics sampled from 16565 (16767) to 16565 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.827), E-opt: 0.2 (0.515), width: 16 Scan time: 2.490 The best scores are: opt bits E(32554) CCDS11555.1 DLX4 gene_id:1748|Hs108|chr17 ( 240) 1665 233.6 8.7e-62 CCDS45728.1 DLX4 gene_id:1748|Hs108|chr17 ( 168) 1017 146.9 8e-36 CCDS47647.2 DLX6 gene_id:1750|Hs108|chr7 ( 293) 537 83.0 2.4e-16 CCDS2247.2 DLX1 gene_id:1745|Hs108|chr2 ( 255) 534 82.5 2.9e-16 CCDS2248.1 DLX2 gene_id:1746|Hs108|chr2 ( 328) 426 68.2 7.5e-12 CCDS11556.1 DLX3 gene_id:1747|Hs108|chr17 ( 287) 406 65.5 4.4e-11 >>CCDS11555.1 DLX4 gene_id:1748|Hs108|chr17 (240 aa) initn: 1665 init1: 1665 opt: 1665 Z-score: 1222.7 bits: 233.6 E(32554): 8.7e-62 Smith-Waterman score: 1665; 100.0% identity (100.0% similar) in 240 aa overlap (1-240:1-240) 10 20 30 40 50 60 pF1KB7 MTSLPCPLPGRDASKAVFPDLAPVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MTSLPCPLPGRDASKAVFPDLAPVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EPANPGDSYLSCQQPAALSQPLCGPAEHPQELEADSEKPRLSPEPSERRPQAPAKKLRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EPANPGDSYLSCQQPAALSQPLCGPAEHPQELEADSEKPRLSPEPSERRPQAPAKKLRKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 RTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM 190 200 210 220 230 240 >>CCDS45728.1 DLX4 gene_id:1748|Hs108|chr17 (168 aa) initn: 1008 init1: 1008 opt: 1017 Z-score: 756.6 bits: 146.9 E(32554): 8e-36 Smith-Waterman score: 1017; 89.1% identity (89.7% similar) in 174 aa overlap (70-240:3-168) 40 50 60 70 80 90 pF1KB7 AASPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQP---LCGPAEHPQELEADS :: : .: : :: : : :: CCDS45 MKLSVLPPRSLLAPYTVLCCP---P-----DS 10 20 100 110 120 130 140 150 pF1KB7 EKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 EKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGL 30 40 50 60 70 80 160 170 180 190 200 210 pF1KB7 TQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTS 90 100 110 120 130 140 220 230 240 pF1KB7 GYGNSFGAWYQHHSSDVLASPQMM :::::::::::::::::::::::: CCDS45 GYGNSFGAWYQHHSSDVLASPQMM 150 160 >>CCDS47647.2 DLX6 gene_id:1750|Hs108|chr7 (293 aa) initn: 463 init1: 438 opt: 537 Z-score: 407.0 bits: 83.0 E(32554): 2.4e-16 Smith-Waterman score: 537; 40.6% identity (62.5% similar) in 251 aa overlap (5-240:48-293) 10 20 30 pF1KB7 MTSLPCPLPGRDASKAVFPDLAPVPSVAAAYPLG : : : . :. : .: .: ::: CCDS47 KSAFMEFGQQQQQQQQQQQQQQQQQQQPPPPPPPPPQPHSQQSSPAMA-----GAHYPLH 20 30 40 50 60 70 40 50 60 70 80 pF1KB7 LSPTTAASPNLSYSRPYGHLLSYPYTEPANPGDS-----------YLSCQQPAALSQPLC ..::. . . . : . . :. : . :.: .: . : CCDS47 CLHSAAAAAAAGSHHHHHHQHHHHGSPYASGGGNSYNHRSLAAYPYMSHSQHSPYLQSYH 80 90 100 110 120 130 90 100 110 120 130 140 pF1KB7 GPAEHPQELEADSEKPRLSP-EPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYL . . : :... . . : .: : .. .::.::::::::::::: ::.:::.:::: CCDS47 NSSAAAQTRGDDTDQQKTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYL 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB7 ALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLP ::::::.:::.::::::::::::::::::.::::::.:. .:.: . ..:: :: :: CCDS47 ALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNPHESDPLQGSAALSPRSPALP 200 210 220 230 240 250 210 220 230 240 pF1KB7 SLWDLP---KAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM .::. :. ..: ..: ... ::. .:.. :::: CCDS47 PVWDVSASAKGVSMPPNSYMPGYSHWYSSPHQDTMQRPQMM 260 270 280 290 >>CCDS2247.2 DLX1 gene_id:1745|Hs108|chr2 (255 aa) initn: 498 init1: 404 opt: 534 Z-score: 405.6 bits: 82.5 E(32554): 2.9e-16 Smith-Waterman score: 547; 43.9% identity (63.0% similar) in 262 aa overlap (1-240:3-255) 10 20 30 40 pF1KB7 MTSLPCPLPGRDASKAVF-----PD--LAPVPSVAAAYPL------GLS-PTTAASPN ::..: : . ..:::: :. ..: : . : . : : : : : CCDS22 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 LSYSRPYGHLLSYPYTEPANPGDS--YLSCQQPAALSQPLCGPA-EHPQELEADSEKPRL :.::: : :::.. .. : :.: : : : : : ::::: . CCDS22 SSFSRPLG----YPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPG---ADSEKSTV 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 SPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQV : .: : .. .::.::::::::::::: ::.:::.::::::::::.:::.:::::::: CCDS22 V-EGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQV 120 130 140 150 160 170 170 180 190 200 210 pF1KB7 KIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSG---- ::::::::::.:::.::.... ::. . ..: :::.: :. :.... :: CCDS22 KIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWN-PNSSSGKGSGGNAG 180 190 200 210 220 230 220 230 240 pF1KB7 -YGNSFGAWYQHHSSDVLASPQMM : :. .:: .... .::.: CCDS22 SYIPSYTSWYPSAHQEAMQQPQLM 240 250 >>CCDS2248.1 DLX2 gene_id:1746|Hs108|chr2 (328 aa) initn: 393 init1: 337 opt: 426 Z-score: 326.2 bits: 68.2 E(32554): 7.5e-12 Smith-Waterman score: 426; 46.0% identity (64.0% similar) in 189 aa overlap (50-224:83-264) 20 30 40 50 60 70 pF1KB7 DLAPVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYTE------PANPGDSYLSCQ ::.:. :: : : . .:: CCDS22 SPTLPVSTATDSSYYTNQQHPAGGGGGGGSPYAHMGSYQYQASGLNNVPYSAKSSYDLGY 60 70 80 90 100 110 80 90 100 110 120 130 pF1KB7 QPAALSQPLCGPAEHPQELEADSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLN : : : . : :..: . . :: : .. ::.:::::::::.:: :. CCDS22 TAAYTSYAPYGTSSSP----ANNEPEKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQ 120 130 140 150 160 140 150 160 170 180 190 pF1KB7 QRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFS .:::.::::::::::.:::.::::::::::::::.:::.::. :.. .: . :: . : CCDS22 RRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPSE-QHPGASAS 170 180 190 200 210 220 200 210 220 230 240 pF1KB7 VSPC-SPPL--PSLWDL--PK---AGTLPTSGYGNSFGAWYQHHSSDVLASPQMM :: :::. :. ::. :. .: : :: :.. :. CCDS22 -PPCASPPVSAPASWDFGVPQRMAGGGGPGSG-GSGAGSSGSSPSSAASAFLGNYPWYHQ 230 240 250 260 270 280 CCDS22 TSGSASHLQATAPLLHPTQTPQPHHHHHHHGGGGAPVSAGTIF 290 300 310 320 >>CCDS11556.1 DLX3 gene_id:1747|Hs108|chr17 (287 aa) initn: 410 init1: 342 opt: 406 Z-score: 312.5 bits: 65.5 E(32554): 4.4e-11 Smith-Waterman score: 411; 41.6% identity (58.8% similar) in 221 aa overlap (2-212:18-223) 10 20 30 pF1KB7 MTSLPCPLPGRDAS---KAVFPDL----APVPSVAAAYPLG--L .:: : ..:. .. :: :: . .. : : . CCDS11 MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTV 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 SPTTAASP-NLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPLCGPAEHPQELEA .: : ::. : .: . : :: : : ::: ::. : .. CCDS11 NPYTYHHQFNLNGLAGTG---AYSPKSEYTYGASYR--QYGAYREQPL--PAQDPVSVKE 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 DSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQL . :: : .. ::.::::::::: :: :..:::..:::::::::.::::: CCDS11 E-------PEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQL 120 130 140 150 160 160 170 180 190 200 210 pF1KB7 GLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLP :::::::::::::.:::.::: :.. : . :. . :.. ::: :.::: . .: CCDS11 GLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHS-PNNSDSMACNSPPSPALWDTSSHSTPA 170 180 190 200 210 220 220 230 240 pF1KB7 TSGYGNSFGAWYQHHSSDVLASPQMM CCDS11 PARSQLPPPLPYSASPSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGA 230 240 250 260 270 280 240 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 09:52:40 2016 done: Sat Nov 5 09:52:40 2016 Total Scan time: 2.490 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]