FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7511, 125 aa 1>>>pF1KB7511 125 - 125 aa - 125 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1140+/-0.000234; mu= 9.7097+/- 0.015 mean_var=119.4932+/-23.467, 0's: 0 Z-trim(125.5): 60 B-trim: 0 in 0/60 Lambda= 0.117328 statistics sampled from 49284 (49353) to 49284 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.871), E-opt: 0.2 (0.579), width: 16 Scan time: 4.400 The best scores are: opt bits E(85289) NP_006390 (OMIM: 612476) basic leucine zipper tran ( 125) 825 148.6 2.5e-36 NP_061134 (OMIM: 612470) basic leucine zipper tran ( 127) 327 64.3 6.1e-11 NP_612465 (OMIM: 614983) basic leucine zipper tran ( 274) 244 50.5 1.8e-06 XP_016876463 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 211 44.7 5.9e-05 XP_016876464 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 211 44.7 5.9e-05 NP_001128520 (OMIM: 608657) jun dimerization prote ( 163) 211 44.7 5.9e-05 NP_569736 (OMIM: 608657) jun dimerization protein ( 163) 211 44.7 5.9e-05 XP_005267389 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 211 44.7 5.9e-05 XP_016876462 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 211 44.7 5.9e-05 NP_001128519 (OMIM: 608657) jun dimerization prote ( 163) 211 44.7 5.9e-05 XP_016876461 (OMIM: 608657) PREDICTED: jun dimeriz ( 174) 211 44.8 6.2e-05 NP_001128521 (OMIM: 608657) jun dimerization prote ( 174) 211 44.8 6.2e-05 NP_001193413 (OMIM: 603148) cyclic AMP-dependent t ( 124) 208 44.1 6.9e-05 NP_001193417 (OMIM: 603148) cyclic AMP-dependent t ( 124) 208 44.1 6.9e-05 XP_016876460 (OMIM: 608657) PREDICTED: jun dimeriz ( 206) 211 44.8 7e-05 NP_001665 (OMIM: 603148) cyclic AMP-dependent tran ( 181) 208 44.3 9.1e-05 XP_005273203 (OMIM: 603148) PREDICTED: cyclic AMP- ( 181) 208 44.3 9.1e-05 NP_001025458 (OMIM: 603148) cyclic AMP-dependent t ( 181) 208 44.3 9.1e-05 XP_011507881 (OMIM: 603148) PREDICTED: cyclic AMP- ( 181) 208 44.3 9.1e-05 XP_016857172 (OMIM: 612470) PREDICTED: basic leuci ( 138) 202 43.1 0.00015 NP_005429 (OMIM: 136515) fos-related antigen 1 iso ( 271) 189 41.2 0.0011 NP_001287785 (OMIM: 136515) fos-related antigen 1 ( 205) 187 40.8 0.0012 XP_016859226 (OMIM: 601575) PREDICTED: fos-related ( 287) 187 40.9 0.0015 NP_005244 (OMIM: 601575) fos-related antigen 2 [Ho ( 326) 187 41.0 0.0016 XP_005258748 (OMIM: 164772) PREDICTED: protein fos ( 237) 183 40.2 0.0021 NP_006723 (OMIM: 164772) protein fosB isoform 1 [H ( 338) 183 40.3 0.0027 NP_005243 (OMIM: 164810) proto-oncogene c-Fos [Hom ( 380) 177 39.3 0.0059 >>NP_006390 (OMIM: 612476) basic leucine zipper transcri (125 aa) initn: 825 init1: 825 opt: 825 Z-score: 773.1 bits: 148.6 E(85289): 2.5e-36 Smith-Waterman score: 825; 100.0% identity (100.0% similar) in 125 aa overlap (1-125:1-125) 10 20 30 40 50 60 pF1KB7 MPHSSDSSDSSFSRSPPPGKQDSSDDVRRVQRREKNRIAAQKSRQRQTQKADTLHLESED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MPHSSDSSDSSFSRSPPPGKQDSSDDVRRVQRREKNRIAAQKSRQRQTQKADTLHLESED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAASTPSPPEVVYSAHAFHQPHVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAASTPSPPEVVYSAHAFHQPHVSS 70 80 90 100 110 120 pF1KB7 PRFQP ::::: NP_006 PRFQP >>NP_061134 (OMIM: 612470) basic leucine zipper transcri (127 aa) initn: 333 init1: 295 opt: 327 Z-score: 317.4 bits: 64.3 E(85289): 6.1e-11 Smith-Waterman score: 327; 54.3% identity (77.2% similar) in 92 aa overlap (16-104:25-116) 10 20 30 40 50 pF1KB7 MPHSSDSSDSSFSRSPPPGKQDSSDDVRRVQRREKNRIAAQKSRQRQTQKA : : .:. :: :.:.::::::.:::.::..::::: NP_061 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA 10 20 30 40 50 60 60 70 80 90 100 pF1KB7 DTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAAS---TPSPPEVVY : :: : :.::..:. ::.:: .::::::..: .:. :: .: .: .: :: NP_061 DKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDP 70 80 90 100 110 120 110 120 pF1KB7 SAHAFHQPHVSSPRFQP NP_061 VAGCLPR >>NP_612465 (OMIM: 614983) basic leucine zipper transcri (274 aa) initn: 263 init1: 230 opt: 244 Z-score: 237.2 bits: 50.5 E(85289): 1.8e-06 Smith-Waterman score: 244; 47.0% identity (74.7% similar) in 83 aa overlap (21-103:12-94) 10 20 30 40 50 60 pF1KB7 MPHSSDSSDSSFSRSPPPGKQDSSDDVRRVQRREKNRIAAQKSRQRQTQKADTLHLESED : . . .: ...::: :::.:::..:.:::.:: . :. NP_612 MHLCGGNGLLTQTDPKEQQRQLKKQKNRAAAQRSRQKHTDKADALHQQHES 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 LEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAASTPSPPEVVYSAHAFHQPHVSS :::.: ::::::..: :: ... .:. :: :: . :: .: NP_612 LEKDNLALRKEIQSLQAELAWWSRTLHVHERLCPMDCASCSAPGLLGCWDQAEGLLGPGP 60 70 80 90 100 110 pF1KB7 PRFQP NP_612 QGQHGCREQLELFQTPGSCYPAQPLSPGPQPHDSPSLLQCPLPSLSLGPAVVAEPPVQLS 120 130 140 150 160 170 >>XP_016876463 (OMIM: 608657) PREDICTED: jun dimerizatio (163 aa) initn: 206 init1: 186 opt: 211 Z-score: 209.9 bits: 44.7 E(85289): 5.9e-05 Smith-Waterman score: 211; 35.5% identity (71.0% similar) in 93 aa overlap (12-103:57-149) 10 20 30 40 pF1KB7 MPHSSDSSDSSFSRSPPPGKQD-SSDDVRRVQRREKNRIAA ... : : :.. . .. :: .:::::..:: XP_016 SSALTVEELKYADIRNLGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAA 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB7 QKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAAST . :... .... :. ::: :: .:: :. .:..: .: . . .:: :.: : : . :. XP_016 ARCRNKKKERTEFLQRESERLELMNAELKTQIEELKQERQQLILMLNRHRPTCIVRTDSV 90 100 110 120 130 140 110 120 pF1KB7 PSPPEVVYSAHAFHQPHVSSPRFQP .: XP_016 KTPESEGNPLLEQLEKK 150 160 >>XP_016876464 (OMIM: 608657) PREDICTED: jun dimerizatio (163 aa) initn: 206 init1: 186 opt: 211 Z-score: 209.9 bits: 44.7 E(85289): 5.9e-05 Smith-Waterman score: 211; 35.5% identity (71.0% similar) in 93 aa overlap (12-103:57-149) 10 20 30 40 pF1KB7 MPHSSDSSDSSFSRSPPPGKQD-SSDDVRRVQRREKNRIAA ... : : :.. . .. :: .:::::..:: XP_016 SSALTVEELKYADIRNLGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAA 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB7 QKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAAST . :... .... :. ::: :: .:: :. .:..: .: . . .:: :.: : : . :. XP_016 ARCRNKKKERTEFLQRESERLELMNAELKTQIEELKQERQQLILMLNRHRPTCIVRTDSV 90 100 110 120 130 140 110 120 pF1KB7 PSPPEVVYSAHAFHQPHVSSPRFQP .: XP_016 KTPESEGNPLLEQLEKK 150 160 >>NP_001128520 (OMIM: 608657) jun dimerization protein 2 (163 aa) initn: 206 init1: 186 opt: 211 Z-score: 209.9 bits: 44.7 E(85289): 5.9e-05 Smith-Waterman score: 211; 35.5% identity (71.0% similar) in 93 aa overlap (12-103:57-149) 10 20 30 40 pF1KB7 MPHSSDSSDSSFSRSPPPGKQD-SSDDVRRVQRREKNRIAA ... : : :.. . .. :: .:::::..:: NP_001 SSALTVEELKYADIRNLGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAA 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB7 QKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAAST . :... .... :. ::: :: .:: :. .:..: .: . . .:: :.: : : . :. NP_001 ARCRNKKKERTEFLQRESERLELMNAELKTQIEELKQERQQLILMLNRHRPTCIVRTDSV 90 100 110 120 130 140 110 120 pF1KB7 PSPPEVVYSAHAFHQPHVSSPRFQP .: NP_001 KTPESEGNPLLEQLEKK 150 160 >>NP_569736 (OMIM: 608657) jun dimerization protein 2 is (163 aa) initn: 206 init1: 186 opt: 211 Z-score: 209.9 bits: 44.7 E(85289): 5.9e-05 Smith-Waterman score: 211; 35.5% identity (71.0% similar) in 93 aa overlap (12-103:57-149) 10 20 30 40 pF1KB7 MPHSSDSSDSSFSRSPPPGKQD-SSDDVRRVQRREKNRIAA ... : : :.. . .. :: .:::::..:: NP_569 SSALTVEELKYADIRNLGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAA 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB7 QKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAAST . :... .... :. ::: :: .:: :. .:..: .: . . .:: :.: : : . :. NP_569 ARCRNKKKERTEFLQRESERLELMNAELKTQIEELKQERQQLILMLNRHRPTCIVRTDSV 90 100 110 120 130 140 110 120 pF1KB7 PSPPEVVYSAHAFHQPHVSSPRFQP .: NP_569 KTPESEGNPLLEQLEKK 150 160 >>XP_005267389 (OMIM: 608657) PREDICTED: jun dimerizatio (163 aa) initn: 206 init1: 186 opt: 211 Z-score: 209.9 bits: 44.7 E(85289): 5.9e-05 Smith-Waterman score: 211; 35.5% identity (71.0% similar) in 93 aa overlap (12-103:57-149) 10 20 30 40 pF1KB7 MPHSSDSSDSSFSRSPPPGKQD-SSDDVRRVQRREKNRIAA ... : : :.. . .. :: .:::::..:: XP_005 SSALTVEELKYADIRNLGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAA 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB7 QKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAAST . :... .... :. ::: :: .:: :. .:..: .: . . .:: :.: : : . :. XP_005 ARCRNKKKERTEFLQRESERLELMNAELKTQIEELKQERQQLILMLNRHRPTCIVRTDSV 90 100 110 120 130 140 110 120 pF1KB7 PSPPEVVYSAHAFHQPHVSSPRFQP .: XP_005 KTPESEGNPLLEQLEKK 150 160 >>XP_016876462 (OMIM: 608657) PREDICTED: jun dimerizatio (163 aa) initn: 206 init1: 186 opt: 211 Z-score: 209.9 bits: 44.7 E(85289): 5.9e-05 Smith-Waterman score: 211; 35.5% identity (71.0% similar) in 93 aa overlap (12-103:57-149) 10 20 30 40 pF1KB7 MPHSSDSSDSSFSRSPPPGKQD-SSDDVRRVQRREKNRIAA ... : : :.. . .. :: .:::::..:: XP_016 SSALTVEELKYADIRNLGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAA 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB7 QKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAAST . :... .... :. ::: :: .:: :. .:..: .: . . .:: :.: : : . :. XP_016 ARCRNKKKERTEFLQRESERLELMNAELKTQIEELKQERQQLILMLNRHRPTCIVRTDSV 90 100 110 120 130 140 110 120 pF1KB7 PSPPEVVYSAHAFHQPHVSSPRFQP .: XP_016 KTPESEGNPLLEQLEKK 150 160 >>NP_001128519 (OMIM: 608657) jun dimerization protein 2 (163 aa) initn: 206 init1: 186 opt: 211 Z-score: 209.9 bits: 44.7 E(85289): 5.9e-05 Smith-Waterman score: 211; 35.5% identity (71.0% similar) in 93 aa overlap (12-103:57-149) 10 20 30 40 pF1KB7 MPHSSDSSDSSFSRSPPPGKQD-SSDDVRRVQRREKNRIAA ... : : :.. . .. :: .:::::..:: NP_001 SSALTVEELKYADIRNLGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAA 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB7 QKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAAST . :... .... :. ::: :: .:: :. .:..: .: . . .:: :.: : : . :. NP_001 ARCRNKKKERTEFLQRESERLELMNAELKTQIEELKQERQQLILMLNRHRPTCIVRTDSV 90 100 110 120 130 140 110 120 pF1KB7 PSPPEVVYSAHAFHQPHVSSPRFQP .: NP_001 KTPESEGNPLLEQLEKK 150 160 125 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:19:00 2016 done: Fri Nov 4 08:19:01 2016 Total Scan time: 4.400 Total Display time: -0.050 Function used was FASTA [36.3.4 Apr, 2011]