FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7514, 245 aa
1>>>pF1KB7514 245 - 245 aa - 245 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0466+/-0.000642; mu= 13.8041+/- 0.039
mean_var=129.9519+/-26.356, 0's: 0 Z-trim(115.9): 190 B-trim: 12 in 1/50
Lambda= 0.112508
statistics sampled from 16301 (16508) to 16301 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.822), E-opt: 0.2 (0.507), width: 16
Scan time: 2.690
The best scores are: opt bits E(32554)
CCDS33640.1 ISX gene_id:91464|Hs108|chr22 ( 245) 1733 291.3 3.9e-79
CCDS11972.1 RAX gene_id:30062|Hs108|chr18 ( 346) 378 71.6 7.9e-13
CCDS12112.1 RAX2 gene_id:84839|Hs108|chr19 ( 184) 358 68.0 4.9e-12
CCDS31468.1 ALX4 gene_id:60529|Hs108|chr11 ( 411) 350 67.1 2.1e-11
CCDS819.1 ALX3 gene_id:257|Hs108|chr1 ( 343) 339 65.2 6.3e-11
>>CCDS33640.1 ISX gene_id:91464|Hs108|chr22 (245 aa)
initn: 1733 init1: 1733 opt: 1733 Z-score: 1534.2 bits: 291.3 E(32554): 3.9e-79
Smith-Waterman score: 1733; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245)
10 20 30 40 50 60
pF1KB7 MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 AASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARIN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 LPEARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LPEARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 PTSCCPSAQDQLASAWFPAWITLLPAHPWETQPVPGLPIHQTCIPVLCILPPPHPKWGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PTSCCPSAQDQLASAWFPAWITLLPAHPWETQPVPGLPIHQTCIPVLCILPPPHPKWGSI
190 200 210 220 230 240
pF1KB7 CATST
:::::
CCDS33 CATST
>>CCDS11972.1 RAX gene_id:30062|Hs108|chr18 (346 aa)
initn: 429 init1: 344 opt: 378 Z-score: 343.8 bits: 71.6 E(32554): 7.9e-13
Smith-Waterman score: 379; 35.3% identity (58.9% similar) in 224 aa overlap (20-235:73-281)
10 20 30 40
pF1KB7 MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEAILKRPARRSDMDRP
: .::.. : : :: . . ::
CCDS11 KDDGILGTFPAERGARGAKERDRRLGARPACPKAPEEGSEPSPPPA--PAPAPEYEAPRP
50 60 70 80 90 100
50 60 70 80 90 100
pF1KB7 EGPGEEG-----PGEAAASGSGLEK-PPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHF
: : : :: .. ..: : ..:: .:..:: :::::: ::::::. :.
CCDS11 YCPKEPGEARPSPGLPVGPATGEAKLSEEEQP---KKKHRRNRTTFTTYQLHELERAFEK
110 120 130 140 150
110 120 130 140 150 160
pF1KB7 THYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALPTNL
.:::::. : .::...::::.:::.::::.:::::.:::. . ..:... . ..
CCDS11 SHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEV--SSMKLQDSPL---LSF
160 170 180 190 200 210
170 180 190 200 210 220
pF1KB7 DVAGPTWTSTALRRLAPPTSCCPSAQDQLASAWF-PAWITLLPAHPWET-QPVPGLPIHQ
. . :. : . : .: .. :.. .:. : ::. . : .::.
CCDS11 SRSPPSATLSPLGA-GPGSGGGPAGGALPLESWLGPP----LPGGGATALQSLPGFGPPA
220 230 240 250 260
230 240
pF1KB7 TCIPVLCILPPPHPKWGSICATST
.:. ::: :
CCDS11 QSLPASYTPPPPPPPFLNSPPLGPGLQPLAPPPPSYPCGPGFGDKFPLDEADPRNSSIAA
270 280 290 300 310 320
>>CCDS12112.1 RAX2 gene_id:84839|Hs108|chr19 (184 aa)
initn: 441 init1: 302 opt: 358 Z-score: 329.6 bits: 68.0 E(32554): 4.9e-12
Smith-Waterman score: 358; 39.2% identity (63.6% similar) in 176 aa overlap (57-227:5-169)
30 40 50 60 70 80
pF1KB7 LSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEAAASGSGLEKPPKDQPQEGRKSKRRVR
:::. :. .: : .. : .:..:: :
CCDS12 MFLSPGEGPATEGGGLGPGEEAP---KKKHRRNR
10 20 30
90 100 110 120 130 140
pF1KB7 TTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKI---
::::: :::.::. :. .:::::. : .:::...:::.:::.::::.:::::.::..
CCDS12 TTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESG
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB7 -GNLGAPQQLSEASVALPTNLDVAGPTWTSTALRR-LAPPTSCCPSAQDQLASAWFPAWI
: ..::. : :: ::: : : : :. :.: :. :. . :.
CCDS12 SGAVAAPR-LPEAP-ALP----FARPPAMSLPLEPWLGPGPPAVPGLPRLLGPG--PGLQ
100 110 120 130 140
210 220 230 240
pF1KB7 TLLPAHPWETQPVPGLPIHQTCIPVLCILPPPHPKWGSICATST
. . : . . :. .... . .:
CCDS12 ASFGPHAFAPTFADGFALEEASLRLLAKEHAQALDRAWPPA
150 160 170 180
>>CCDS31468.1 ALX4 gene_id:60529|Hs108|chr11 (411 aa)
initn: 317 init1: 317 opt: 350 Z-score: 318.3 bits: 67.1 E(32554): 2.1e-11
Smith-Waterman score: 357; 35.6% identity (55.0% similar) in 222 aa overlap (19-208:127-338)
10 20 30 40
pF1KB7 MCAEVGPALCRGMERNSLGCCEAPKKLSL-----SFSIEAILKRP--A
: :..: :: : . : :. : :
CCDS31 PQPQPPPQPQPQQQQPQPQPPAQPHLYLQRGACKTPPDGSLKLQEGSSGHSAALQVPCYA
100 110 120 130 140 150
50 60 70 80
pF1KB7 RRSDMDRPEGP------------------GEEGPGEAAASGSGLEKPPKDQPQEGRKSK-
..:.. .:: : : .:: . :.: : .: . .:. :.:
CCDS31 KESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASS--DLPSPLEKADSESNKGKK
160 170 180 190 200 210
90 100 110 120 130 140
pF1KB7 RRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEK
:: :::::. ::.::::.:. ::::::. : ::: : .: :::::.::::.::::::.:.
CCDS31 RRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRER
220 230 240 250 260 270
150 160 170 180 190
pF1KB7 IGNLGAPQQLSEASVALP------TNLDVAGPTWTSTALRRLAPPTSCCPSAQDQLASAW
.:.. . .. :: . .. .:.: .. : :. : : . .
CCDS31 FGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGN--NGAASPVPACVVPCDPVPACM
280 290 300 310 320 330
200 210 220 230 240
pF1KB7 FPAWITLLPAHPWETQPVPGLPIHQTCIPVLCILPPPHPKWGSICATST
: :::
CCDS31 SPH------AHPPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASLSPGLNGYELNGEP
340 350 360 370 380
>>CCDS819.1 ALX3 gene_id:257|Hs108|chr1 (343 aa)
initn: 414 init1: 307 opt: 339 Z-score: 309.6 bits: 65.2 E(32554): 6.3e-11
Smith-Waterman score: 353; 36.1% identity (53.9% similar) in 241 aa overlap (6-240:78-281)
10 20 30
pF1KB7 MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEA
:::: : . : :: .: : . :.
CCDS81 LTRFPACGPLEPYLPEPAKPPAKYLQDLGPGPALNGGHFYE--GPAEAEEKTSKAASFPQ
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB7 ILKRPARRSDMDRPEG-PGEEGPGEAAAS---GSGLEKPPKDQPQEGRKSKRRVRTTFTT
: : . : : . : :: :. . :: : . . .....::: ::::.:
CCDS81 -LPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGL--PDSMELAKNKSKKRRNRTTFST
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB7 EQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNLGAPQQ
::.::::.:. ::::::. : ::: : .: :::::.::::.::::::.:. : .
CCDS81 FQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYG------K
170 180 190 200 210
160 170 180 190 200 210
pF1KB7 LSEASVALPTNLDVAGPTWTSTALRRLAPPTSCCPSAQDQLASAWFPAWITLLPAHPWET
..:. . . :.. . : :. :. :..: : : :
CCDS81 IQEGRNPFTAAYDIS-----------VLPRTDSHPQLQNSL---W---------ASP--G
220 230 240 250
220 230 240
pF1KB7 QPVPGLP--IHQTCIPVLCILPPPHPKWGSICATST
. :: : . :: :. : ::. ::.
CCDS81 SGSPGGPCLVSPEGIPSPCMSPYSHPH-GSVAGFMGVPAPSAAHPGIYSIHGFPPTLGGH
260 270 280 290 300 310
CCDS81 SFEPSSDGDYKSPSLVSLRVKPKEPPGLLNWTT
320 330 340
245 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 08:21:23 2016 done: Fri Nov 4 08:21:23 2016
Total Scan time: 2.690 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]