FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7514, 245 aa 1>>>pF1KB7514 245 - 245 aa - 245 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0466+/-0.000642; mu= 13.8041+/- 0.039 mean_var=129.9519+/-26.356, 0's: 0 Z-trim(115.9): 190 B-trim: 12 in 1/50 Lambda= 0.112508 statistics sampled from 16301 (16508) to 16301 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.822), E-opt: 0.2 (0.507), width: 16 Scan time: 2.690 The best scores are: opt bits E(32554) CCDS33640.1 ISX gene_id:91464|Hs108|chr22 ( 245) 1733 291.3 3.9e-79 CCDS11972.1 RAX gene_id:30062|Hs108|chr18 ( 346) 378 71.6 7.9e-13 CCDS12112.1 RAX2 gene_id:84839|Hs108|chr19 ( 184) 358 68.0 4.9e-12 CCDS31468.1 ALX4 gene_id:60529|Hs108|chr11 ( 411) 350 67.1 2.1e-11 CCDS819.1 ALX3 gene_id:257|Hs108|chr1 ( 343) 339 65.2 6.3e-11 >>CCDS33640.1 ISX gene_id:91464|Hs108|chr22 (245 aa) initn: 1733 init1: 1733 opt: 1733 Z-score: 1534.2 bits: 291.3 E(32554): 3.9e-79 Smith-Waterman score: 1733; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245) 10 20 30 40 50 60 pF1KB7 MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 AASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARIN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LPEARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LPEARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PTSCCPSAQDQLASAWFPAWITLLPAHPWETQPVPGLPIHQTCIPVLCILPPPHPKWGSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 PTSCCPSAQDQLASAWFPAWITLLPAHPWETQPVPGLPIHQTCIPVLCILPPPHPKWGSI 190 200 210 220 230 240 pF1KB7 CATST ::::: CCDS33 CATST >>CCDS11972.1 RAX gene_id:30062|Hs108|chr18 (346 aa) initn: 429 init1: 344 opt: 378 Z-score: 343.8 bits: 71.6 E(32554): 7.9e-13 Smith-Waterman score: 379; 35.3% identity (58.9% similar) in 224 aa overlap (20-235:73-281) 10 20 30 40 pF1KB7 MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEAILKRPARRSDMDRP : .::.. : : :: . . :: CCDS11 KDDGILGTFPAERGARGAKERDRRLGARPACPKAPEEGSEPSPPPA--PAPAPEYEAPRP 50 60 70 80 90 100 50 60 70 80 90 100 pF1KB7 EGPGEEG-----PGEAAASGSGLEK-PPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHF : : : :: .. ..: : ..:: .:..:: :::::: ::::::. :. CCDS11 YCPKEPGEARPSPGLPVGPATGEAKLSEEEQP---KKKHRRNRTTFTTYQLHELERAFEK 110 120 130 140 150 110 120 130 140 150 160 pF1KB7 THYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALPTNL .:::::. : .::...::::.:::.::::.:::::.:::. . ..:... . .. CCDS11 SHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEV--SSMKLQDSPL---LSF 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB7 DVAGPTWTSTALRRLAPPTSCCPSAQDQLASAWF-PAWITLLPAHPWET-QPVPGLPIHQ . . :. : . : .: .. :.. .:. : ::. . : .::. CCDS11 SRSPPSATLSPLGA-GPGSGGGPAGGALPLESWLGPP----LPGGGATALQSLPGFGPPA 220 230 240 250 260 230 240 pF1KB7 TCIPVLCILPPPHPKWGSICATST .:. ::: : CCDS11 QSLPASYTPPPPPPPFLNSPPLGPGLQPLAPPPPSYPCGPGFGDKFPLDEADPRNSSIAA 270 280 290 300 310 320 >>CCDS12112.1 RAX2 gene_id:84839|Hs108|chr19 (184 aa) initn: 441 init1: 302 opt: 358 Z-score: 329.6 bits: 68.0 E(32554): 4.9e-12 Smith-Waterman score: 358; 39.2% identity (63.6% similar) in 176 aa overlap (57-227:5-169) 30 40 50 60 70 80 pF1KB7 LSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEAAASGSGLEKPPKDQPQEGRKSKRRVR :::. :. .: : .. : .:..:: : CCDS12 MFLSPGEGPATEGGGLGPGEEAP---KKKHRRNR 10 20 30 90 100 110 120 130 140 pF1KB7 TTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKI--- ::::: :::.::. :. .:::::. : .:::...:::.:::.::::.:::::.::.. CCDS12 TTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESG 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB7 -GNLGAPQQLSEASVALPTNLDVAGPTWTSTALRR-LAPPTSCCPSAQDQLASAWFPAWI : ..::. : :: ::: : : : :. :.: :. :. . :. CCDS12 SGAVAAPR-LPEAP-ALP----FARPPAMSLPLEPWLGPGPPAVPGLPRLLGPG--PGLQ 100 110 120 130 140 210 220 230 240 pF1KB7 TLLPAHPWETQPVPGLPIHQTCIPVLCILPPPHPKWGSICATST . . : . . :. .... . .: CCDS12 ASFGPHAFAPTFADGFALEEASLRLLAKEHAQALDRAWPPA 150 160 170 180 >>CCDS31468.1 ALX4 gene_id:60529|Hs108|chr11 (411 aa) initn: 317 init1: 317 opt: 350 Z-score: 318.3 bits: 67.1 E(32554): 2.1e-11 Smith-Waterman score: 357; 35.6% identity (55.0% similar) in 222 aa overlap (19-208:127-338) 10 20 30 40 pF1KB7 MCAEVGPALCRGMERNSLGCCEAPKKLSL-----SFSIEAILKRP--A : :..: :: : . : :. : : CCDS31 PQPQPPPQPQPQQQQPQPQPPAQPHLYLQRGACKTPPDGSLKLQEGSSGHSAALQVPCYA 100 110 120 130 140 150 50 60 70 80 pF1KB7 RRSDMDRPEGP------------------GEEGPGEAAASGSGLEKPPKDQPQEGRKSK- ..:.. .:: : : .:: . :.: : .: . .:. :.: CCDS31 KESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASS--DLPSPLEKADSESNKGKK 160 170 180 190 200 210 90 100 110 120 130 140 pF1KB7 RRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEK :: :::::. ::.::::.:. ::::::. : ::: : .: :::::.::::.::::::.:. CCDS31 RRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRER 220 230 240 250 260 270 150 160 170 180 190 pF1KB7 IGNLGAPQQLSEASVALP------TNLDVAGPTWTSTALRRLAPPTSCCPSAQDQLASAW .:.. . .. :: . .. .:.: .. : :. : : . . CCDS31 FGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGN--NGAASPVPACVVPCDPVPACM 280 290 300 310 320 330 200 210 220 230 240 pF1KB7 FPAWITLLPAHPWETQPVPGLPIHQTCIPVLCILPPPHPKWGSICATST : ::: CCDS31 SPH------AHPPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASLSPGLNGYELNGEP 340 350 360 370 380 >>CCDS819.1 ALX3 gene_id:257|Hs108|chr1 (343 aa) initn: 414 init1: 307 opt: 339 Z-score: 309.6 bits: 65.2 E(32554): 6.3e-11 Smith-Waterman score: 353; 36.1% identity (53.9% similar) in 241 aa overlap (6-240:78-281) 10 20 30 pF1KB7 MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEA :::: : . : :: .: : . :. CCDS81 LTRFPACGPLEPYLPEPAKPPAKYLQDLGPGPALNGGHFYE--GPAEAEEKTSKAASFPQ 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB7 ILKRPARRSDMDRPEG-PGEEGPGEAAAS---GSGLEKPPKDQPQEGRKSKRRVRTTFTT : : . : : . : :: :. . :: : . . .....::: ::::.: CCDS81 -LPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGL--PDSMELAKNKSKKRRNRTTFST 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB7 EQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNLGAPQQ ::.::::.:. ::::::. : ::: : .: :::::.::::.::::::.:. : . CCDS81 FQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYG------K 170 180 190 200 210 160 170 180 190 200 210 pF1KB7 LSEASVALPTNLDVAGPTWTSTALRRLAPPTSCCPSAQDQLASAWFPAWITLLPAHPWET ..:. . . :.. . : :. :. :..: : : : CCDS81 IQEGRNPFTAAYDIS-----------VLPRTDSHPQLQNSL---W---------ASP--G 220 230 240 250 220 230 240 pF1KB7 QPVPGLP--IHQTCIPVLCILPPPHPKWGSICATST . :: : . :: :. : ::. ::. CCDS81 SGSPGGPCLVSPEGIPSPCMSPYSHPH-GSVAGFMGVPAPSAAHPGIYSIHGFPPTLGGH 260 270 280 290 300 310 CCDS81 SFEPSSDGDYKSPSLVSLRVKPKEPPGLLNWTT 320 330 340 245 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:21:23 2016 done: Fri Nov 4 08:21:23 2016 Total Scan time: 2.690 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]