FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7515, 127 aa 1>>>pF1KB7515 127 - 127 aa - 127 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7437+/-0.000244; mu= 7.9088+/- 0.016 mean_var=152.5276+/-30.024, 0's: 0 Z-trim(126.3): 49 B-trim: 7 in 2/55 Lambda= 0.103848 statistics sampled from 51739 (51807) to 51739 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.879), E-opt: 0.2 (0.607), width: 16 Scan time: 5.870 The best scores are: opt bits E(85289) NP_061134 (OMIM: 612470) basic leucine zipper tran ( 127) 867 139.3 1.6e-33 XP_016857172 (OMIM: 612470) PREDICTED: basic leuci ( 138) 453 77.4 7.7e-15 NP_006390 (OMIM: 612476) basic leucine zipper tran ( 125) 327 58.4 3.5e-09 NP_612465 (OMIM: 614983) basic leucine zipper tran ( 274) 249 47.1 2e-05 NP_001193417 (OMIM: 603148) cyclic AMP-dependent t ( 124) 199 39.3 0.002 NP_001193413 (OMIM: 603148) cyclic AMP-dependent t ( 124) 199 39.3 0.002 XP_005273203 (OMIM: 603148) PREDICTED: cyclic AMP- ( 181) 199 39.4 0.0027 NP_001665 (OMIM: 603148) cyclic AMP-dependent tran ( 181) 199 39.4 0.0027 NP_001025458 (OMIM: 603148) cyclic AMP-dependent t ( 181) 199 39.4 0.0027 XP_011507881 (OMIM: 603148) PREDICTED: cyclic AMP- ( 181) 199 39.4 0.0027 XP_016876464 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 197 39.1 0.0031 NP_001128519 (OMIM: 608657) jun dimerization prote ( 163) 197 39.1 0.0031 NP_569736 (OMIM: 608657) jun dimerization protein ( 163) 197 39.1 0.0031 XP_016876462 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 197 39.1 0.0031 NP_001128520 (OMIM: 608657) jun dimerization prote ( 163) 197 39.1 0.0031 XP_016876463 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 197 39.1 0.0031 XP_005267389 (OMIM: 608657) PREDICTED: jun dimeriz ( 163) 197 39.1 0.0031 NP_001128521 (OMIM: 608657) jun dimerization prote ( 174) 197 39.1 0.0032 XP_016876461 (OMIM: 608657) PREDICTED: jun dimeriz ( 174) 197 39.1 0.0032 XP_016876460 (OMIM: 608657) PREDICTED: jun dimeriz ( 206) 197 39.2 0.0036 NP_001287785 (OMIM: 136515) fos-related antigen 1 ( 205) 191 38.3 0.0067 >>NP_061134 (OMIM: 612470) basic leucine zipper transcri (127 aa) initn: 867 init1: 867 opt: 867 Z-score: 723.0 bits: 139.3 E(85289): 1.6e-33 Smith-Waterman score: 867; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KB7 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 DKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDP 70 80 90 100 110 120 pF1KB7 VAGCLPR ::::::: NP_061 VAGCLPR >>XP_016857172 (OMIM: 612470) PREDICTED: basic leucine z (138 aa) initn: 605 init1: 437 opt: 453 Z-score: 387.4 bits: 77.4 E(85289): 7.7e-15 Smith-Waterman score: 453; 71.4% identity (81.9% similar) in 105 aa overlap (1-105:1-100) 10 20 30 40 50 60 pF1KB7 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDP ::::: : ... .: .: .: :.: . .:. : : .: XP_016 DKLHE----LMERTIFLITQIRSLGFILSH-SFSLRPHAYTCIILQLGRGAAPYQELALK 70 80 90 100 110 pF1KB7 VAGCLPR XP_016 ASKDLSEEWATIPCSCLCRGWCV 120 130 >>NP_006390 (OMIM: 612476) basic leucine zipper transcri (125 aa) initn: 333 init1: 295 opt: 327 Z-score: 285.9 bits: 58.4 E(85289): 3.5e-09 Smith-Waterman score: 327; 54.3% identity (77.2% similar) in 92 aa overlap (25-116:16-104) 10 20 30 40 50 60 pF1KB7 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA : : .:. :: :.:.::::::.:::.::..::::: NP_006 MPHSSDSSDSSFSRSPPPGKQDSSDDVRRVQRREKNRIAAQKSRQRQTQKA 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 DKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDP : :: : :.::..:. ::.:: .::::::..: .:. :: .: .: .: :: NP_006 DTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAAS---TPSPPEVVY 60 70 80 90 100 pF1KB7 VAGCLPR NP_006 SAHAFHQPHVSSPRFQP 110 120 >>NP_612465 (OMIM: 614983) basic leucine zipper transcri (274 aa) initn: 270 init1: 224 opt: 249 Z-score: 218.4 bits: 47.1 E(85289): 2e-05 Smith-Waterman score: 249; 47.4% identity (84.2% similar) in 76 aa overlap (29-104:12-86) 10 20 30 40 50 60 pF1KB7 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA : .:....:.... .:::.::::::.:.:.:: NP_612 MHLCGGNGLLTQTDPKEQQRQLKK-QKNRAAAQRSRQKHTDKA 10 20 30 40 70 80 90 100 110 120 pF1KB7 DKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDP : ::...::::..: ::.:: .: :: ...:. ::..::. NP_612 DALHQQHESLEKDNLALRKEIQSLQAELAWWSRTLHVHERLCPMDCASCSAPGLLGCWDQ 50 60 70 80 90 100 pF1KB7 VAGCLPR NP_612 AEGLLGPGPQGQHGCREQLELFQTPGSCYPAQPLSPGPQPHDSPSLLQCPLPSLSLGPAV 110 120 130 140 150 160 >>NP_001193417 (OMIM: 603148) cyclic AMP-dependent trans (124 aa) initn: 283 init1: 198 opt: 199 Z-score: 182.3 bits: 39.3 E(85289): 0.002 Smith-Waterman score: 199; 41.7% identity (75.0% similar) in 72 aa overlap (31-102:25-96) 10 20 30 40 50 60 pF1KB7 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA .::.:.:: ::::.:..:: . :.:. .:. NP_001 MSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKT 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 DKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDP . :..: :.::. :. :. .: .: .: .:: :. :. : NP_001 ECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFI 60 70 80 90 100 110 pF1KB7 VAGCLPR NP_001 QQIKEGTLQS 120 >>NP_001193413 (OMIM: 603148) cyclic AMP-dependent trans (124 aa) initn: 283 init1: 198 opt: 199 Z-score: 182.3 bits: 39.3 E(85289): 0.002 Smith-Waterman score: 199; 41.7% identity (75.0% similar) in 72 aa overlap (31-102:25-96) 10 20 30 40 50 60 pF1KB7 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA .::.:.:: ::::.:..:: . :.:. .:. NP_001 MSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKT 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 DKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDP . :..: :.::. :. :. .: .: .: .:: :. :. : NP_001 ECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFI 60 70 80 90 100 110 pF1KB7 VAGCLPR NP_001 QQIKEGTLQS 120 >>XP_005273203 (OMIM: 603148) PREDICTED: cyclic AMP-depe (181 aa) initn: 268 init1: 198 opt: 199 Z-score: 180.2 bits: 39.4 E(85289): 0.0027 Smith-Waterman score: 199; 41.7% identity (75.0% similar) in 72 aa overlap (31-102:82-153) 10 20 30 40 50 60 pF1KB7 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA .::.:.:: ::::.:..:: . :.:. .:. XP_005 KHLCHRMSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKT 60 70 80 90 100 110 70 80 90 100 110 120 pF1KB7 DKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDP . :..: :.::. :. :. .: .: .: .:: :. :. : XP_005 ECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFI 120 130 140 150 160 170 pF1KB7 VAGCLPR XP_005 QQIKEGTLQS 180 >>NP_001665 (OMIM: 603148) cyclic AMP-dependent transcri (181 aa) initn: 268 init1: 198 opt: 199 Z-score: 180.2 bits: 39.4 E(85289): 0.0027 Smith-Waterman score: 199; 41.7% identity (75.0% similar) in 72 aa overlap (31-102:82-153) 10 20 30 40 50 60 pF1KB7 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA .::.:.:: ::::.:..:: . :.:. .:. NP_001 KHLCHRMSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKT 60 70 80 90 100 110 70 80 90 100 110 120 pF1KB7 DKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDP . :..: :.::. :. :. .: .: .: .:: :. :. : NP_001 ECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFI 120 130 140 150 160 170 pF1KB7 VAGCLPR NP_001 QQIKEGTLQS 180 >>NP_001025458 (OMIM: 603148) cyclic AMP-dependent trans (181 aa) initn: 268 init1: 198 opt: 199 Z-score: 180.2 bits: 39.4 E(85289): 0.0027 Smith-Waterman score: 199; 41.7% identity (75.0% similar) in 72 aa overlap (31-102:82-153) 10 20 30 40 50 60 pF1KB7 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA .::.:.:: ::::.:..:: . :.:. .:. NP_001 KHLCHRMSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKT 60 70 80 90 100 110 70 80 90 100 110 120 pF1KB7 DKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDP . :..: :.::. :. :. .: .: .: .:: :. :. : NP_001 ECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFI 120 130 140 150 160 170 pF1KB7 VAGCLPR NP_001 QQIKEGTLQS 180 >>XP_011507881 (OMIM: 603148) PREDICTED: cyclic AMP-depe (181 aa) initn: 268 init1: 198 opt: 199 Z-score: 180.2 bits: 39.4 E(85289): 0.0027 Smith-Waterman score: 199; 41.7% identity (75.0% similar) in 72 aa overlap (31-102:82-153) 10 20 30 40 50 60 pF1KB7 MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKA .::.:.:: ::::.:..:: . :.:. .:. XP_011 KHLCHRMSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKT 60 70 80 90 100 110 70 80 90 100 110 120 pF1KB7 DKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDP . :..: :.::. :. :. .: .: .: .:: :. :. : XP_011 ECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFI 120 130 140 150 160 170 pF1KB7 VAGCLPR XP_011 QQIKEGTLQS 180 127 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:21:58 2016 done: Fri Nov 4 08:21:58 2016 Total Scan time: 5.870 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]