FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7518, 246 aa 1>>>pF1KB7518 246 - 246 aa - 246 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1835+/-0.000758; mu= 11.0571+/- 0.046 mean_var=91.4455+/-17.924, 0's: 0 Z-trim(110.6): 9 B-trim: 0 in 0/51 Lambda= 0.134120 statistics sampled from 11712 (11718) to 11712 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.36), width: 16 Scan time: 2.280 The best scores are: opt bits E(32554) CCDS9805.1 MED6 gene_id:10001|Hs108|chr14 ( 246) 1657 330.1 8.5e-91 CCDS73649.1 MED6 gene_id:10001|Hs108|chr14 ( 257) 1651 328.9 2e-90 CCDS61484.1 MED6 gene_id:10001|Hs108|chr14 ( 253) 1633 325.4 2.2e-89 CCDS61483.1 MED6 gene_id:10001|Hs108|chr14 ( 181) 1065 215.5 2e-56 >>CCDS9805.1 MED6 gene_id:10001|Hs108|chr14 (246 aa) initn: 1657 init1: 1657 opt: 1657 Z-score: 1743.6 bits: 330.1 E(32554): 8.5e-91 Smith-Waterman score: 1657; 100.0% identity (100.0% similar) in 246 aa overlap (1-246:1-246) 10 20 30 40 50 60 pF1KB7 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 TAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 LLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPE 190 200 210 220 230 240 pF1KB7 KRMRLQ :::::: CCDS98 KRMRLQ >>CCDS73649.1 MED6 gene_id:10001|Hs108|chr14 (257 aa) initn: 1671 init1: 1651 opt: 1651 Z-score: 1737.0 bits: 328.9 E(32554): 2e-90 Smith-Waterman score: 1651; 99.6% identity (100.0% similar) in 246 aa overlap (1-246:1-246) 10 20 30 40 50 60 pF1KB7 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 TAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 LLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPE 190 200 210 220 230 240 pF1KB7 KRMRLQ :::::. CCDS73 KRMRLHYIILSIKINSC 250 >>CCDS61484.1 MED6 gene_id:10001|Hs108|chr14 (253 aa) initn: 1643 init1: 874 opt: 1633 Z-score: 1718.3 bits: 325.4 E(32554): 2.2e-89 Smith-Waterman score: 1633; 97.2% identity (97.2% similar) in 253 aa overlap (1-246:1-253) 10 20 30 40 50 60 pF1KB7 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRV- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 ------LTAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 LFSFYKLTAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 RQRVDALLLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 RQRVDALLLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTV 190 200 210 220 230 240 240 pF1KB7 SAKGPPEKRMRLQ ::::::::::::: CCDS61 SAKGPPEKRMRLQ 250 >>CCDS61483.1 MED6 gene_id:10001|Hs108|chr14 (181 aa) initn: 1065 init1: 1065 opt: 1065 Z-score: 1126.5 bits: 215.5 E(32554): 2e-56 Smith-Waterman score: 1065; 97.5% identity (98.1% similar) in 162 aa overlap (1-162:1-162) 10 20 30 40 50 60 pF1KB7 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDAL ::::::::::::::::::::::::::::::::::: :. :: CCDS61 TAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQAKAWRKACSSGSNKERGRTYTRNCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPE CCDS61 T 246 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:23:45 2016 done: Fri Nov 4 08:23:46 2016 Total Scan time: 2.280 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]