Result of FASTA (omim) for
pF1KB7518
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7518, 246 aa
1>>>pF1KB7518 246 - 246 aa - 246 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5864+/-0.000319; mu= 8.6327+/- 0.020
mean_var=95.2121+/-18.969, 0's: 0 Z-trim(117.8): 7 B-trim: 0 in 0/53
Lambda= 0.131440
statistics sampled from 30077 (30084) to 30077 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.353), width: 16
Scan time: 6.840
The best scores are: opt bits E(85289)
NP_005457 (OMIM: 602984) mediator of RNA polymeras ( 246) 1657 323.9 1.6e-88
NP_001271140 (OMIM: 602984) mediator of RNA polyme ( 257) 1651 322.8 3.6e-88
NP_001271138 (OMIM: 602984) mediator of RNA polyme ( 253) 1633 319.4 3.8e-87
NP_001271139 (OMIM: 602984) mediator of RNA polyme ( 181) 1065 211.6 7.6e-55
>>NP_005457 (OMIM: 602984) mediator of RNA polymerase II (246 aa)
initn: 1657 init1: 1657 opt: 1657 Z-score: 1710.3 bits: 323.9 E(85289): 1.6e-88
Smith-Waterman score: 1657; 100.0% identity (100.0% similar) in 246 aa overlap (1-246:1-246)
10 20 30 40 50 60
pF1KB7 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 TAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPE
190 200 210 220 230 240
pF1KB7 KRMRLQ
::::::
NP_005 KRMRLQ
>>NP_001271140 (OMIM: 602984) mediator of RNA polymerase (257 aa)
initn: 1671 init1: 1651 opt: 1651 Z-score: 1703.8 bits: 322.8 E(85289): 3.6e-88
Smith-Waterman score: 1651; 99.6% identity (100.0% similar) in 246 aa overlap (1-246:1-246)
10 20 30 40 50 60
pF1KB7 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 TAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPE
190 200 210 220 230 240
pF1KB7 KRMRLQ
:::::.
NP_001 KRMRLHYIILSIKINSC
250
>>NP_001271138 (OMIM: 602984) mediator of RNA polymerase (253 aa)
initn: 1643 init1: 874 opt: 1633 Z-score: 1685.5 bits: 319.4 E(85289): 3.8e-87
Smith-Waterman score: 1633; 97.2% identity (97.2% similar) in 253 aa overlap (1-246:1-253)
10 20 30 40 50 60
pF1KB7 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL
10 20 30 40 50 60
70 80 90 100 110
pF1KB7 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRV-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 ------LTAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFSFYKLTAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQ
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 RQRVDALLLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQRVDALLLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTV
190 200 210 220 230 240
240
pF1KB7 SAKGPPEKRMRLQ
:::::::::::::
NP_001 SAKGPPEKRMRLQ
250
>>NP_001271139 (OMIM: 602984) mediator of RNA polymerase (181 aa)
initn: 1065 init1: 1065 opt: 1065 Z-score: 1105.6 bits: 211.6 E(85289): 7.6e-55
Smith-Waterman score: 1065; 97.5% identity (98.1% similar) in 162 aa overlap (1-162:1-162)
10 20 30 40 50 60
pF1KB7 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 TAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDAL
::::::::::::::::::::::::::::::::::: :. ::
NP_001 TAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQAKAWRKACSSGSNKERGRTYTRNCK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPE
NP_001 T
246 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 08:23:46 2016 done: Fri Nov 4 08:23:47 2016
Total Scan time: 6.840 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]