FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7522, 249 aa 1>>>pF1KB7522 249 - 249 aa - 249 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6238+/-0.000383; mu= 13.6868+/- 0.024 mean_var=73.6324+/-14.747, 0's: 0 Z-trim(113.1): 11 B-trim: 0 in 0/55 Lambda= 0.149465 statistics sampled from 22227 (22236) to 22227 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.261), width: 16 Scan time: 6.740 The best scores are: opt bits E(85289) NP_004119 (OMIM: 189969) general transcription fac ( 249) 1623 359.0 4.4e-99 XP_011533354 (OMIM: 189969) PREDICTED: general tra ( 275) 975 219.3 5.6e-57 XP_016876040 (OMIM: 189969) PREDICTED: general tra ( 149) 970 218.1 7e-57 XP_011533355 (OMIM: 189969) PREDICTED: general tra ( 131) 653 149.7 2.4e-36 XP_016876039 (OMIM: 189969) PREDICTED: general tra ( 193) 653 149.8 3.3e-36 >>NP_004119 (OMIM: 189969) general transcription factor (249 aa) initn: 1623 init1: 1623 opt: 1623 Z-score: 1899.8 bits: 359.0 E(85289): 4.4e-99 Smith-Waterman score: 1623; 100.0% identity (100.0% similar) in 249 aa overlap (1-249:1-249) 10 20 30 40 50 60 pF1KB7 MAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSDKLSLEGIVVQRAECRPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSDKLSLEGIVVQRAECRPAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SENYMRLKRLQIEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDGKRARADK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SENYMRLKRLQIEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDGKRARADK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QHVLDMLFSAFEKHQYYNLKDLVDITKQPVVYLKEILKEIGVQNVKGIHKNTWELKPEYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QHVLDMLFSAFEKHQYYNLKDLVDITKQPVVYLKEILKEIGVQNVKGIHKNTWELKPEYR 190 200 210 220 230 240 pF1KB7 HYQGEEKSD ::::::::: NP_004 HYQGEEKSD >>XP_011533354 (OMIM: 189969) PREDICTED: general transcr (275 aa) initn: 971 init1: 971 opt: 975 Z-score: 1144.0 bits: 219.3 E(85289): 5.6e-57 Smith-Waterman score: 1561; 90.5% identity (90.5% similar) in 275 aa overlap (1-249:1-275) 10 20 30 40 50 60 pF1KB7 MAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNE 10 20 30 40 50 60 70 80 90 100 pF1KB7 DLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSS------------------- ::::::::::::::::::::::::::::::::::::::::: XP_011 DLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSGGSRMTAGVTTVISTSQAS 70 80 90 100 110 120 110 120 130 140 150 pF1KB7 -------DKLSLEGIVVQRAECRPAASENYMRLKRLQIEESSKPVRLSQQLDKVVTTNYK ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGKQDGEDKLSLEGIVVQRAECRPAASENYMRLKRLQIEESSKPVRLSQQLDKVVTTNYK 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 PVANHQYNIEYERKKKEDGKRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVVYLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVANHQYNIEYERKKKEDGKRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVVYLK 190 200 210 220 230 240 220 230 240 pF1KB7 EILKEIGVQNVKGIHKNTWELKPEYRHYQGEEKSD ::::::::::::::::::::::::::::::::::: XP_011 EILKEIGVQNVKGIHKNTWELKPEYRHYQGEEKSD 250 260 270 >>XP_016876040 (OMIM: 189969) PREDICTED: general transcr (149 aa) initn: 970 init1: 970 opt: 970 Z-score: 1142.1 bits: 218.1 E(85289): 7e-57 Smith-Waterman score: 970; 100.0% identity (100.0% similar) in 148 aa overlap (102-249:2-149) 80 90 100 110 120 130 pF1KB7 PASVSAPREHPFVLQSVGGQTLTVFTESSSDKLSLEGIVVQRAECRPAASENYMRLKRLQ :::::::::::::::::::::::::::::: XP_016 MDKLSLEGIVVQRAECRPAASENYMRLKRLQ 10 20 30 140 150 160 170 180 190 pF1KB7 IEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDGKRARADKQHVLDMLFSAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDGKRARADKQHVLDMLFSAF 40 50 60 70 80 90 200 210 220 230 240 pF1KB7 EKHQYYNLKDLVDITKQPVVYLKEILKEIGVQNVKGIHKNTWELKPEYRHYQGEEKSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKHQYYNLKDLVDITKQPVVYLKEILKEIGVQNVKGIHKNTWELKPEYRHYQGEEKSD 100 110 120 130 140 >>XP_011533355 (OMIM: 189969) PREDICTED: general transcr (131 aa) initn: 653 init1: 653 opt: 653 Z-score: 773.6 bits: 149.7 E(85289): 2.4e-36 Smith-Waterman score: 653; 100.0% identity (100.0% similar) in 101 aa overlap (1-101:1-101) 10 20 30 40 50 60 pF1KB7 MAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSDKLSLEGIVVQRAECRPAA ::::::::::::::::::::::::::::::::::::::::: XP_011 DLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSGGSRMTAGVTTVISTSQAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SENYMRLKRLQIEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDGKRARADK XP_011 KGKQDGEGQSA 130 >>XP_016876039 (OMIM: 189969) PREDICTED: general transcr (193 aa) initn: 653 init1: 653 opt: 653 Z-score: 771.0 bits: 149.8 E(85289): 3.3e-36 Smith-Waterman score: 653; 100.0% identity (100.0% similar) in 101 aa overlap (1-101:1-101) 10 20 30 40 50 60 pF1KB7 MAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSDKLSLEGIVVQRAECRPAA ::::::::::::::::::::::::::::::::::::::::: XP_016 DLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSGGSRMTAGVTTVISTSQAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 SENYMRLKRLQIEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDGKRARADK XP_016 KGKQDGEESFLVTQARVQWHDLGSQQPLPPGLKQLSCLSLLSNWDYKCALPTLANYCIFF 130 140 150 160 170 180 249 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:06:36 2016 done: Sat Nov 5 18:06:37 2016 Total Scan time: 6.740 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]