FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7524, 249 aa 1>>>pF1KB7524 249 - 249 aa - 249 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6889+/-0.000899; mu= 10.2894+/- 0.054 mean_var=143.1106+/-27.795, 0's: 0 Z-trim(111.4): 48 B-trim: 94 in 1/52 Lambda= 0.107211 statistics sampled from 12270 (12314) to 12270 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.378), width: 16 Scan time: 2.230 The best scores are: opt bits E(32554) CCDS44813.1 ING4 gene_id:51147|Hs108|chr12 ( 249) 1683 271.2 4.7e-73 CCDS8555.1 ING4 gene_id:51147|Hs108|chr12 ( 248) 1657 267.1 7.7e-72 CCDS44814.1 ING4 gene_id:51147|Hs108|chr12 ( 246) 1642 264.8 3.8e-71 CCDS44815.1 ING4 gene_id:51147|Hs108|chr12 ( 245) 1639 264.4 5.2e-71 CCDS44812.1 ING4 gene_id:51147|Hs108|chr12 ( 225) 1445 234.3 5.3e-62 CCDS44816.1 ING4 gene_id:51147|Hs108|chr12 ( 179) 1064 175.3 2.5e-44 CCDS82586.1 ING5 gene_id:84289|Hs108|chr2 ( 226) 711 120.8 8e-28 CCDS33425.1 ING5 gene_id:84289|Hs108|chr2 ( 240) 711 120.8 8.3e-28 CCDS9516.1 ING1 gene_id:3621|Hs108|chr13 ( 279) 646 110.8 9.9e-25 CCDS82585.1 ING5 gene_id:84289|Hs108|chr2 ( 254) 645 110.6 1e-24 CCDS3833.1 ING2 gene_id:3622|Hs108|chr4 ( 280) 574 99.7 2.2e-21 CCDS9515.1 ING1 gene_id:3621|Hs108|chr13 ( 235) 513 90.2 1.4e-18 CCDS9517.1 ING1 gene_id:3621|Hs108|chr13 ( 422) 515 90.7 1.7e-18 CCDS9518.1 ING1 gene_id:3621|Hs108|chr13 ( 210) 502 88.4 4.1e-18 CCDS5778.1 ING3 gene_id:54556|Hs108|chr7 ( 418) 386 70.8 1.7e-12 >>CCDS44813.1 ING4 gene_id:51147|Hs108|chr12 (249 aa) initn: 1683 init1: 1683 opt: 1683 Z-score: 1425.0 bits: 271.2 E(32554): 4.7e-73 Smith-Waterman score: 1683; 100.0% identity (100.0% similar) in 249 aa overlap (1-249:1-249) 10 20 30 40 50 60 pF1KB7 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 190 200 210 220 230 240 pF1KB7 RCSQERKKK ::::::::: CCDS44 RCSQERKKK >>CCDS8555.1 ING4 gene_id:51147|Hs108|chr12 (248 aa) initn: 865 init1: 865 opt: 1657 Z-score: 1403.3 bits: 267.1 E(32554): 7.7e-72 Smith-Waterman score: 1657; 99.2% identity (99.6% similar) in 249 aa overlap (1-249:1-248) 10 20 30 40 50 60 pF1KB7 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS ::::::::::. :::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 YDSSSSKGKKS-RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 180 190 200 210 220 230 pF1KB7 RCSQERKKK ::::::::: CCDS85 RCSQERKKK 240 >>CCDS44814.1 ING4 gene_id:51147|Hs108|chr12 (246 aa) initn: 862 init1: 862 opt: 1642 Z-score: 1390.8 bits: 264.8 E(32554): 3.8e-71 Smith-Waterman score: 1642; 98.4% identity (98.8% similar) in 249 aa overlap (1-249:1-246) 10 20 30 40 50 60 pF1KB7 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS ::::::: .::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YDSSSSK---EGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 180 190 200 210 220 230 pF1KB7 RCSQERKKK ::::::::: CCDS44 RCSQERKKK 240 >>CCDS44815.1 ING4 gene_id:51147|Hs108|chr12 (245 aa) initn: 859 init1: 859 opt: 1639 Z-score: 1388.3 bits: 264.4 E(32554): 5.2e-71 Smith-Waterman score: 1639; 98.4% identity (98.4% similar) in 249 aa overlap (1-249:1-245) 10 20 30 40 50 60 pF1KB7 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS ::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YDSSSSK----GRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 180 190 200 210 220 230 pF1KB7 RCSQERKKK ::::::::: CCDS44 RCSQERKKK 240 >>CCDS44812.1 ING4 gene_id:51147|Hs108|chr12 (225 aa) initn: 1445 init1: 1445 opt: 1445 Z-score: 1226.6 bits: 234.3 E(32554): 5.3e-62 Smith-Waterman score: 1461; 90.0% identity (90.4% similar) in 249 aa overlap (1-249:1-225) 10 20 30 40 50 60 pF1KB7 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE :::::::::::: .::::::::::::::::::::::: CCDS44 MAAGMYLEHYLD------------------------NLKAEIDKLATEYMSSARSLSSEE 10 20 30 70 80 90 100 110 120 pF1KB7 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB7 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB7 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 160 170 180 190 200 210 pF1KB7 RCSQERKKK ::::::::: CCDS44 RCSQERKKK 220 >>CCDS44816.1 ING4 gene_id:51147|Hs108|chr12 (179 aa) initn: 1080 init1: 1061 opt: 1064 Z-score: 909.4 bits: 175.3 E(32554): 2.5e-44 Smith-Waterman score: 1064; 98.3% identity (98.3% similar) in 172 aa overlap (1-172:1-172) 10 20 30 40 50 60 pF1KB7 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS ::::::::::::::::::::::::::::::::::::::::::::::: : : CCDS44 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSGSILPVWG 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP >>CCDS82586.1 ING5 gene_id:84289|Hs108|chr2 (226 aa) initn: 1003 init1: 580 opt: 711 Z-score: 613.0 bits: 120.8 E(32554): 8e-28 Smith-Waterman score: 1099; 70.3% identity (89.4% similar) in 236 aa overlap (1-236:1-226) 10 20 30 40 50 60 pF1KB7 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE ::..:::::::::::::: ::::::::::.::::::: ::::: ::.::.:....:: .. CCDS82 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD .. :..::.::.::::..::::::::::::::::::::::.::::::::::.: .:.:: CCDS82 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS ..::...: :::: ::::...:.:.. ..:.:..:: .:: : . :. . :. : CCDS82 FESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPK--KKKHK---GGSEF---TDTILS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP ::::::::::::::::::::::::::::::::::::: ::::::::: :::::.:: CCDS82 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGK 180 190 200 210 220 pF1KB7 RCSQERKKK >>CCDS33425.1 ING5 gene_id:84289|Hs108|chr2 (240 aa) initn: 1098 init1: 580 opt: 711 Z-score: 612.7 bits: 120.8 E(32554): 8.3e-28 Smith-Waterman score: 1194; 70.7% identity (89.6% similar) in 249 aa overlap (1-249:1-239) 10 20 30 40 50 60 pF1KB7 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE ::..:::::::::::::: ::::::::::.::::::: ::::: ::.::.:....:: .. CCDS33 MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD .. :..::.::.::::..::::::::::::::::::::::.::::::::::.: .:.:: CCDS33 RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS ..::...: :::: ::::...:.:.. ..:.:..:: .:: : . :. . :. : CCDS33 FESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPK--KKKHK---GGSEF---TDTILS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP ::::::::::::::::::::::::::::::::::::: ::::::::: :::::.:::::: CCDS33 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCP 180 190 200 210 220 230 pF1KB7 RCSQERKKK :: ::..:: CCDS33 RCVQEKRKKK 240 >>CCDS9516.1 ING1 gene_id:3621|Hs108|chr13 (279 aa) initn: 652 init1: 368 opt: 646 Z-score: 557.5 bits: 110.8 E(32554): 9.9e-25 Smith-Waterman score: 646; 39.1% identity (68.8% similar) in 253 aa overlap (6-248:15-262) 10 20 30 40 50 pF1KB7 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMS :.: ::::::.:::.:::: .:::..: . ... :.:. : CCDS95 MLSPANGEQLHLVNYVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDEC---YER 10 20 30 40 50 60 70 80 90 100 pF1KB7 SARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEA-- .: .. .: .:. .:.: . .:.::.:.:.. : :.:... :..:. . ::: CCDS95 FSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQ 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 DLKEKQIESSDYDSSSSKGKKKGRTQKE--KKAARARSK------GKNSDEEAPKTAQKK .: . .:. .. ::. ....: :.. : :.. ..: :.. .. : CCDS95 ELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 LKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEW : ..:: . .. . . .. :.:.::::::::::.:::::::::::: .: ::: CCDS95 EKKAKTSKKKKRSKAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEW 180 190 200 210 220 230 230 240 pF1KB7 FHFACVGLTTKPRGKWFCPRCSQERKKK :::.::::. ::.:::.::.: : .: CCDS95 FHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR 240 250 260 270 >>CCDS82585.1 ING5 gene_id:84289|Hs108|chr2 (254 aa) initn: 628 init1: 507 opt: 645 Z-score: 557.2 bits: 110.6 E(32554): 1e-24 Smith-Waterman score: 645; 59.9% identity (84.2% similar) in 177 aa overlap (11-178:13-187) 10 20 30 40 50 pF1KB7 MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSS : .::::: ::::::::::.::::::: ::::: ::.::.:....:: CCDS82 MGARVTPRDSGGLIGIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 EEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIES .... :..::.::.::::..::::::::::::::::::::::.::::::::::.: .:. CCDS82 DQRVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEG 70 80 90 100 110 120 130 140 150 160 pF1KB7 SDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKK------LKLVRTS---P ::..::...: :::: ::::...:.:.. ..:.:..:: ..: :.: : : CCDS82 SDFESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPKKKKHKGGGNSVLSLPAPSCSEP 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB7 EYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGL : .:.: : CCDS82 EGPVPTVPFLRESGTPPGLFLTQCCFSRWQCCSCPIARRRDRLVRPALKLGSDVQGAKEA 180 190 200 210 220 230 249 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:25:56 2016 done: Fri Nov 4 08:25:56 2016 Total Scan time: 2.230 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]